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Hi Alison

I have the same problem, and i know its not age related as i'm only

24! However I also have very long hair so its normal to some extent to

lose it more frequently than those with short hair. But sometimes

soooo much comes out and it really worries me! My hair is definately a

lot thinner than when i was younger. From what i have read, excess

hair loss is mostly caused from nutrient deficiencies, which can be

caused by the drugs we take and general ill-health. I also ready that

immune disorders can cause this. I think the best way to help is just

by making sure we have an adequate intake of all the necessary

vitamins and minerals which a multi-vitamin would provide; also zinc

and fish oil supplements really help the hair and also skin. I used

to take fish oil supplements but stopped, i plan on starting again to

see if it helps my hair - i'll let you know! Kate (UK)

>

>

>

>

>

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

> of hair. Especially when I shower and wash my hair or run my hands through

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

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I've been on it for years, but recently have dropped the dose because of

other symptoms from MTX. I'm currently on the lowest dose of MTX I've ever

been on at 15mg per week.. It still could be the issue though... Hum...

Thanks .

-- Re: Hair loss

,

I have heard MTX can cause hair loss. Have you started it recently?

Edited By Moderator

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I've been on it for years, but recently have dropped the dose because of

other symptoms from MTX. I'm currently on the lowest dose of MTX I've ever

been on at 15mg per week.. It still could be the issue though... Hum...

Thanks .

-- Re: Hair loss

,

I have heard MTX can cause hair loss. Have you started it recently?

Edited By Moderator

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Hi ,

Yes, I have hair loss/thinning ever since I started on the methotrexate - which

 was about one month after I was diagnosed with Stills...I am still on it

and my hair is very thin..others say it is not bad at all- they are just being

kind because

I know what it feels like and I see it in the sink every morning.......I really

do not have to comb my hair anymore...just a shake of my head and and that's 

it for 'my style'   lol..I quit running my hands through my hair because I dont

have alot!!

The Doc said it was the meds..

Diane..42

Hi all

Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

of hair. Especially when I shower and wash my hair or run my hands through

my hair. I can run my hands through my hair and easily have 10-20 hairs on

my hands. This can happen multiple times in a day.

I see my RD on Thursday and plan on talking to him about it, but I thought I

d see if anyone else has experienced this problem.

Thanks,

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Hi ,

Yes, I have hair loss/thinning ever since I started on the methotrexate - which

 was about one month after I was diagnosed with Stills...I am still on it

and my hair is very thin..others say it is not bad at all- they are just being

kind because

I know what it feels like and I see it in the sink every morning.......I really

do not have to comb my hair anymore...just a shake of my head and and that's 

it for 'my style'   lol..I quit running my hands through my hair because I dont

have alot!!

The Doc said it was the meds..

Diane..42

Hi all

Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

of hair. Especially when I shower and wash my hair or run my hands through

my hair. I can run my hands through my hair and easily have 10-20 hairs on

my hands. This can happen multiple times in a day.

I see my RD on Thursday and plan on talking to him about it, but I thought I

d see if anyone else has experienced this problem.

Thanks,

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and Kate

I have been taking the fish oil too...didnt help the hair from thinning..

this is from the methotrexate I am on.

Diane..42

Hi Alison

I have the same problem, and i know its not age related as i'm only

24! However I also have very long hair so its normal to some extent to

lose it more frequently than those with short hair. But sometimes

soooo much comes out and it really worries me! My hair is definately a

lot thinner than when i was younger. From what i have read, excess

hair loss is mostly caused from nutrient deficiencies, which can be

caused by the drugs we take and general ill-health. I also ready that

immune disorders can cause this. I think the best way to help is just

by making sure we have an adequate intake of all the necessary

vitamins and minerals which a multi-vitamin would provide; also zinc

and fish oil supplements really help the hair and also skin. I used

to take fish oil supplements but stopped, i plan on starting again to

see if it helps my hair - i'll let you know! Kate (UK)

>

>

>

>

>

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

> of hair. Especially when I shower and wash my hair or run my hands through

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

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and Kate

I have been taking the fish oil too...didnt help the hair from thinning..

this is from the methotrexate I am on.

Diane..42

Hi Alison

I have the same problem, and i know its not age related as i'm only

24! However I also have very long hair so its normal to some extent to

lose it more frequently than those with short hair. But sometimes

soooo much comes out and it really worries me! My hair is definately a

lot thinner than when i was younger. From what i have read, excess

hair loss is mostly caused from nutrient deficiencies, which can be

caused by the drugs we take and general ill-health. I also ready that

immune disorders can cause this. I think the best way to help is just

by making sure we have an adequate intake of all the necessary

vitamins and minerals which a multi-vitamin would provide; also zinc

and fish oil supplements really help the hair and also skin. I used

to take fish oil supplements but stopped, i plan on starting again to

see if it helps my hair - i'll let you know! Kate (UK)

>

>

>

>

>

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

> of hair. Especially when I shower and wash my hair or run my hands through

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

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Guest guest

I've never had a hair loss problem. And I've been on metho. since I was real

little though it's probably because I've had really short hair since I was a

kid. But my Mom had that problem from a beta blocker she was taking and she has

really, really long hair. She's been taking biotin since it helps with hair and

nail growth.

: )

----- Original Message ----

and Kate

I have been taking the fish oil too...didnt help the hair from thinning..

this is from the methotrexate I am on.

Diane..42

Hi Alison

I have the same problem, and i know its not age related as i'm only

24! However I also have very long hair so its normal to some extent to

lose it more frequently than those with short hair. But sometimes

soooo much comes out and it really worries me! My hair is definately a

lot thinner than when i was younger. From what i have read, excess

hair loss is mostly caused from nutrient deficiencies, which can be

caused by the drugs we take and general ill-health. I also ready that

immune disorders can cause this. I think the best way to help is just

by making sure we have an adequate intake of all the necessary

vitamins and minerals which a multi-vitamin would provide; also zinc

and fish oil supplements really help the hair and also skin. I used

to take fish oil supplements but stopped, i plan on starting again to

see if it helps my hair - i'll let you know! Kate (UK)

On 07/04/2008, allison laptop <allisonartpixu (DOT) com> wrote:

>

>

>

>

>

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

> of hair. Especially when I shower and wash my hair or run my hands through

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

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Guest guest

I've never had a hair loss problem. And I've been on metho. since I was real

little though it's probably because I've had really short hair since I was a

kid. But my Mom had that problem from a beta blocker she was taking and she has

really, really long hair. She's been taking biotin since it helps with hair and

nail growth.

: )

----- Original Message ----

and Kate

I have been taking the fish oil too...didnt help the hair from thinning..

this is from the methotrexate I am on.

Diane..42

Hi Alison

I have the same problem, and i know its not age related as i'm only

24! However I also have very long hair so its normal to some extent to

lose it more frequently than those with short hair. But sometimes

soooo much comes out and it really worries me! My hair is definately a

lot thinner than when i was younger. From what i have read, excess

hair loss is mostly caused from nutrient deficiencies, which can be

caused by the drugs we take and general ill-health. I also ready that

immune disorders can cause this. I think the best way to help is just

by making sure we have an adequate intake of all the necessary

vitamins and minerals which a multi-vitamin would provide; also zinc

and fish oil supplements really help the hair and also skin. I used

to take fish oil supplements but stopped, i plan on starting again to

see if it helps my hair - i'll let you know! Kate (UK)

On 07/04/2008, allison laptop <allisonartpixu (DOT) com> wrote:

>

>

>

>

>

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

> of hair. Especially when I shower and wash my hair or run my hands through

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

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Guest guest

just thought i'd add that I have this problem but i'm not on MTX, so

it could just be the condition or maybe the other drugs i am on

(Tocilizumab and Prednisolone)

Kate

>

>

>

>

>

>

>

>

> Hi ,

>

> Yes, I have hair loss/thinning ever since I started on the methotrexate -

> which

>

> was about one month after I was diagnosed with Stills...I am still on it

>

> and my hair is very thin..others say it is not bad at all- they are just

> being kind because

>

> I know what it feels like and I see it in the sink every morning.......I

> really

>

> do not have to comb my hair anymore...just a shake of my head and and

> that's

>

> it for 'my style' lol..I quit running my hands through my hair because I

> dont have alot!!

>

> The Doc said it was the meds..

>

> Diane..42

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

>

> of hair. Especially when I shower and wash my hair or run my hands through

>

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

>

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

>

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

>

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Guest guest

just thought i'd add that I have this problem but i'm not on MTX, so

it could just be the condition or maybe the other drugs i am on

(Tocilizumab and Prednisolone)

Kate

>

>

>

>

>

>

>

>

> Hi ,

>

> Yes, I have hair loss/thinning ever since I started on the methotrexate -

> which

>

> was about one month after I was diagnosed with Stills...I am still on it

>

> and my hair is very thin..others say it is not bad at all- they are just

> being kind because

>

> I know what it feels like and I see it in the sink every morning.......I

> really

>

> do not have to comb my hair anymore...just a shake of my head and and

> that's

>

> it for 'my style' lol..I quit running my hands through my hair because I

> dont have alot!!

>

> The Doc said it was the meds..

>

> Diane..42

>

> Hi all

>

> Has anyone ever had a lot of hair loss with stills? Lately I'm losing a lot

>

> of hair. Especially when I shower and wash my hair or run my hands through

>

> my hair. I can run my hands through my hair and easily have 10-20 hairs on

>

> my hands. This can happen multiple times in a day.

>

> I see my RD on Thursday and plan on talking to him about it, but I thought

> I

>

> d see if anyone else has experienced this problem.

>

> Thanks,

>

>

>

>

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Guest guest

,

If it's not a side effect of one of your medications, have you had

your thyroid check? Hair loss is a symptom of under active thyroid.

let us know what you figure out.

Houston

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,

If it's not a side effect of one of your medications, have you had

your thyroid check? Hair loss is a symptom of under active thyroid.

let us know what you figure out.

Houston

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,

If it's not a side effect of one of your medications, have you had

your thyroid check? Hair loss is a symptom of under active thyroid.

let us know what you figure out.

Houston

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Guest guest

Since you know she's taking your nutritional advice, the mostly

likely cause is genetic predisposition. You may suggest that her

family doctor check her thyroid levels. They may be too high or

low, and both can cause hair loss. If she was on thryoid

replacement hormone before surgery, she probably needs an adjustment

in dosage by now anyway.

Other rarer causes could be ringworm, a bad perm job, or autoimmune

problems like lupus.

--Becky , RD

>

> Hi Group,

> I have a pt who is 4 months post-bypass with significant hair

loss.

> She is extremely concerned with this and is doing everything I

tell

> her (protein, MVI, B-complex). Is there anything else that might

help

> this pt not lose anymore hair?? Thank You! -

>

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Hair loss occurs at 3 to 5 months post-op because of a protein deficit in the

first few weeks after surgery. It's a delayed effect. As long as she's getting

enough protein, calories, biotin, zinc, and iron now, the hair loss should stop

and begin regrowing by 6 months post-op. There's not much else she can do. If

it continues for longer than 6 months post-op, then something else is the cause.

Sent via BlackBerry from T-Mobile

Re: hair loss

Since you know she's taking your nutritional advice, the mostly

likely cause is genetic predisposition. You may suggest that her

family doctor check her thyroid levels. They may be too high or

low, and both can cause hair loss. If she was on thryoid

replacement hormone before surgery, she probably needs an adjustment

in dosage by now anyway.

Other rarer causes could be ringworm, a bad perm job, or autoimmune

problems like lupus.

--Becky , RD

>

> Hi Group,

> I have a pt who is 4 months post-bypass with significant hair

loss.

> She is extremely concerned with this and is doing everything I

tell

> her (protein, MVI, B-complex). Is there anything else that might

help

> this pt not lose anymore hair?? Thank You! -

>

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Telogen effluvium (rapid hair shedding) can occur as a result of

rapid weight loss. Nutritional deficiencies can contribute to

increased hair shedding by weakening hair shafts that cause breakage

to the hair and slow regrowth. Principal nutrients that are involved

include vitamin A, certain B vitamins, biotin, vitamin C, copper,

iron, zinc, and protein--all of which are malabsorbed by gastric

bypass patients. Surgery and anesthesia can also result

in temporary hair loss. With time, adequate protein, and vitamin

supplements, hair loss will subside.

See also Neve, H.J., et al. " Reversal of Hair Loss following

Vertical Gastroplasty when Treated with Zinc Sulphate. " Obesity

Surgery. 6(1): 63-65.

Ava

>

> Hi Group,

> I have a pt who is 4 months post-bypass with significant hair

loss.

> She is extremely concerned with this and is doing everything I

tell

> her (protein, MVI, B-complex). Is there anything else that might

help

> this pt not lose anymore hair?? Thank You! -

>

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,

She might need biotin. There is no known toxicity for biotin, although it

is good to be sure magnesium is OK when you supplement biotin. I suspect

the RDA was set far too low because this is a vitamin we get from our

flora, and their production of biotin may be reduced by treatments with

antibiotics.

Please read the articles below to get a feel for a connection between

biotin deficiency and hair loss.

1: J Pediatr. 1985 May;106(5):762-9.

Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic

repercussions, and treatment.

Mock DM, Baswell DL, Baker H, Holman RT, Sweetman L.

Biotin deficiency associated with total parenteral nutrition is an emerging

clinical problem; criteria for diagnosis and dosage for treatment are

unclear. We

have diagnosed and successfully treated biotin deficiency in three

patients. Each

patient had alopecia totalis, hypotonia, and developmental delay. Two developed

the characteristic scaly periorificial dermatitis; one had only an intermittent

scaly rash on the cheeks and occipital scalp. Zinc and essential fatty acid

supplements were adequate; serum zinc levels and triene/tetraene ratios

confirmed

sufficiency of these nutrients. None of the patients received biotin prior to

diagnosis, and each had decreased excretion of urinary biotin and increased

urinary excretion of organic acids diagnostic of deficiency of two

biotin-dependent enzymes (methylcrotonyl-coenzyme A carboxylase and

priopionyl-coenzyme A carboxylase). Only one patient had a plasma biotin

concentration below the normal range (Ochromonicas danica assay). The rash,

alopecia, and neurologic findings responded dramatically to biotin therapy (100

micrograms/day in all patients; an initial larger dose of 1 mg/day for 1 week

plus 10 mg/day for 7 weeks in one patient), and did not recur. However,

abnormal

organic acid excretion persisted in one patient who did not receive the larger

dose. We conclude that plasma biotin concentration does not reflect biotin

status

in all cases and speculate that the biotin supplement currently recommended for

pediatric patients (20 micrograms/day) may not be adequate therapy for biotin

deficiency and might not even be adequate to maintain normal biotin status

during

TPN.

Publication Types:

Case Reports

Research Support, Non-U.S. Gov't

Research Support, U.S. Gov't, P.H.S.

PMID: 3923177 [PubMed - indexed for MEDLINE]

2: JPEN J Parenter Enteral Nutr. 1984 May-Jun;8(3):311-4.

Biotin deficiency in a patient with short bowel syndrome during home parenteral

nutrition.

Khalidi N, Wesley JR, Thoene JG, Whitehouse WM Jr, Baker WL.

A 54-year-old woman with short bowel syndrome was supported with home

parenteral

nutrition. Six months after receiving 2200 kcal/day of balanced home parenteral

nutrition without biotin, she developed biotin deficiency with complete hair

loss, eczematous dermatitis, waxy pallor, lethargy, and hypersthesias .

Blood and

urine samples were collected prior to treatment. Serum zinc was 64

micrograms/dl

(nl 50-150 micrograms/dl), and the triene/tetraene ratio was 0.068 (nl 0.4),

thereby ruling out zinc and essential fatty acid deficiencies. Serum biotin was

332 pg/ml (nl 520 +/- 220 pg/ml), and urine biotin was 5.22 ng/mg of creatinine

(nl 4.3-95 with a mean of 30.2 ng/mg creatinine). The same parenteral nutrition

regimen was contained and oral biotin was administered (10 mg/day). After 3 wk,

serum and urine biotin levels were 650 pg/ml and 35.6 ng/mg creatinine,

respectively. New hair growth was evident and all of her other symptoms

resolved.

Intravenous biotin was then provided (5 mg/day) for a month after which

serum and

urine biotin levels were 1316 pg/ml and 178 ng/mg creatine, respectively. The

patient has been subsequently maintained on an intravenous multivitamin product

containing 60 micrograms biotin per daily dose and remains free of signs and

symptoms of biotin deficiency.

Publication Types:

Case Reports

PMID: 6429370 [PubMed - indexed for MEDLINE]

3: J Am Acad Dermatol. 1983 Jul;9(1):97-103.

Alopecia and periorificial dermatitis in biotin-responsive multiple carboxylase

deficiency.

ML, Packman S, Cowan MJ.

Three siblings with infantile-onset biotin-responsive multiple carboxylase

deficiency are described. Recognition of the characteristic dermatologic

manifestations, alopecia and periorificial dermatitis, should result in early

diagnosis and institution of potentially lifesaving therapy with biotin. Other

metabolic disorders may present a similar clinical picture. Immunologic

dysfunction and/or aberration in lipid or branched chain amino acid metabolism

may be the common pathophysiologic link in some or all of these disorders.

Publication Types:

Case Reports

Research Support, Non-U.S. Gov't

Research Support, U.S. Gov't, P.H.S.

PMID: 6886110 [PubMed - indexed for MEDLINE]

4: Am J Clin Nutr. 1983 Feb;37(2):185-7.

Possible biotin deficiency in adults receiving long-term total parenteral

nutrition.

Innis SM, Allardyce DB.

Two adult patients receiving total parenteral nutrition on a long-term home

basis

presented with severe loss of hair. Both patients had extensive gut resection,

consumed no biotin orally and received no biotin parenterally. Supplementation

with Berroca-C, one ampule containing 200 micrograms biotin per day resulted in

gradual regrowth of healthy hair. The patients now receive a parenteral

solution

containing biotin and have shown no recurrence of alopecia. It is suggested

that

biotin deficiency can occur in the adult when no preformed biotin is

provided to

the body and the contribution of this vitamin from intestinal microbial

biosynthesis is compromised.

Publication Types:

Case Reports

PMID: 6401910 [PubMed - indexed for MEDLINE]

5: Pediatrics. 1981 Oct;68(4):553-8.

Clinical and metabolic abnormalities in a boy with dietary deficiency of

biotin.

Sweetman L, Surh L, Baker H, RM, Nyhan WL.

Dietary deficiency of biotin was documented in an 11-year-old retarded boy as a

consequence of a dietary prescription containing raw eggs. Clinical

manifestations were alopecia totalis and an erythematous, exfoliative

dermatosis.

Metabolic characteristics included increased excretion of

3-methylcrotonylglycine, 3-hydroxyisovaleric acid, 3-hydroxypropionic acid,

methylcitric acid, and lactic acid, as well as a propensity for the development

of ketosis. The activities of propionyl coenzyme A carboxylase and

3-methylcrotonyl coenzyme A carboxylase in extracts of leukocytes were

deficient.

Treatment with biotin and the removal of raw eggs, which contain the

biotin-binding protein, avidin, from the diet led to the reversal of all of the

clinical and metabolic manifestations observed.

Publication Types:

Case Reports

Research Support, U.S. Gov't, Non-P.H.S.

Research Support, U.S. Gov't, P.H.S.

PMID: 7322688 [PubMed - indexed for MEDLINE]

6: Lancet. 1979 Jul 21;2(8134):118-20.

Biotin-responsive alopecia and developmental regression.

BM, Hosking G, Green A, Pollitt R, Bartlett K, Taitz LS.

A 10-month-old boy presented with dermatitis and alopecia and became severely

hypotonic. Screening for urinary organic acids revealed a large quantity of

3-hydroxyisovaleric acid and raised levels of beta-methylcrotonylglycine and

3-hydroxypropionate. Activities of propionyl CoA carboxylase,

beta-methylcrotonyl

CoA carboxylase, and pyruvate carboxylase in cultured fibroblasts were normal.

Treatment with oral biotin resulted in a dramatic clinical improvement, which

might therefore suggest a defect in biotin absorption or transport.

Publication Types:

Case Reports

PMID: 88555 [PubMed - indexed for MEDLINE]

7: Pol Med J. 1966;5(2):447-52.

Effect of biotin on hair roots and sebum excretion in women with diffuse

alopecia.

Pawlowski A, Kostanecki W.

Publication Types:

Clinical Trial

Controlled Clinical Trial

PMID: 4223823 [PubMed - indexed for MEDLINE]

At 08:19 PM 4/17/2008, you wrote:

>Hi Group,

>I have a pt who is 4 months post-bypass with significant hair loss.

>She is extremely concerned with this and is doing everything I tell

>her (protein, MVI, B-complex). Is there anything else that might help

>this pt not lose anymore hair?? Thank You! -

>

>

No virus found in this outgoing message.

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Version: 7.5.519 / Virus Database: 269.23.0/1379 - Release Date: 4/15/2008 6:10

PM

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"Some time ago there was a posting on compounded rogain with other ingredients. It was affordable and had better results. I've decided to hang on to what little hair I have left and any info on this subject and where to obtain this is much appreciated."I just use generic minoxidil. It's available at any drug store or grocery store, next to brand name Rogaine. Sometimes, Rogaine has good coupons that make it as cheap as generic.JB

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I developed this product but the manufacturer closed down, so I am looking for a new onehttp://regenase.com/ Regards, VergelPoWeRUSA.orgFrom: AZ <bayconoeggs@...> Sent: Mon, September 13, 2010 7:40:42 PMSubject: Hair loss

Some time ago there was a posting on compounded rogain with other ingredients. It was affordable and had better results. I've decided to hang on to what little hair I have left and any info on this subject and where to obtain this is much appreciated.------------------------------------Welcome to our group!If you received this email from someone who forwarded it to you and would like to join this group, send a blank email to -subscribe and you will get an email with instructions to follow.You can chose to receive single emails or a daily digest (collection of emails). You can post pictures, images, attach files and search by keyword old postings in the group.For those of you who are members already and want to switch from single emails to digest or vice

versa, visit www., click on , then on "edit my membership" and go down to your selection. The list administrator does not process any requests, so this is a do-it-yourself easy process ! :)Thanks for joining. You will learn and share a lot in this group!NOTE: I moderate, approve or disapprove emails before they are posted. Please follow the guidelines shown in the homepage. I will not allow rudeness, sexually explicit material, attacks, and anyone who does not follow the rules. If you are not OK with this, please do not join the group. Forward this email to anyone who may benefit from this information! Thanks!In Health, Vergel (PoWeRTX@...)List Founder and Moderator

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"I developed this product but the manufacturer closed down, so I am looking for a "I think the use of an antifungal as a baldness treatment is quite misguided. Ketoconazole resistance in the community is already a problem; this can only worsen it, more rapidly.JB

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JBInteresting observation, although your term "misguided" is assuming resistance that develops to trandermal exposure of ketoconazole.I talked to the makers of Nizoral shampoo and they have not had any reports of ketoconazole resistance. But of course, they may not have a lot of immune compromised patients. I have used it for 10 years with no problems. I have had no fungal infections at all. And I have 200 CD4 cells. I have had no occurrence of Candida. It is hard to say what would happen in a person with detectable HIV viral load with under 100 CD4 cells. Would they have fungal resistance if they used a tiny amount of ketoconazole in a shampoo or gel? I would love to see a reference on

that,Wikipedia has a reference on your comment. http://en.wikipedia.org/wiki/Ketoconazole Regards, VergelPoWeRUSA.orgFrom: Barrow <barrowster@...> Sent: Wed, September 15, 2010 12:10:03 PMSubject: Re: Hair loss

"I developed this product but the manufacturer closed down, so I am looking for a "I think the use of an antifungal as a baldness treatment is quite misguided. Ketoconazole resistance in the community is already a problem; this can only worsen it, more rapidly.JB

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"As an antiandrogen, ketoconazole operates through at least two mechanisms of action. First, and most notably, high oral doses of ketoconazole (e.g. 400 mg 3x/day) block both testicular and adrenal androgen biosynthesis, leading to a reduction in circulating testosterone levels.[15] Ketoconazole produces this effect through inhibition of cytochrome P450 and 17,20-lyase, which are involved in the synthesis and degradation of steroids, including the precursors of testosterone. Due to its efficacy at reducing systemic androgen levels, ketoconazole has been used as a treatment for androgen-dependent prostate cancer.[16] Second, ketoconazole is an androgen receptor antagonist, competing with androgens such as testosterone and DHT for androgen receptor binding. This effect is thought to be quite weak, even with high oral doses of ketoconazole.[17]"Just like Proscar, but more........On Sep 15, 2010, at 6:07 PM, Vergel wrote:JBInteresting observation, although your term "misguided" is assuming resistance that develops to trandermal exposure of ketoconazole.I talked to the makers of Nizoral shampoo and they have not had any reports of ketoconazole resistance. But of course, they may not have a lot of immune compromised patients. I have used it for 10 years with no problems. I have had no fungal infections at all. And I have 200 CD4 cells. I have had no occurrence of Candida. It is hard to say what would happen in a person with detectable HIV viral load with under 100 CD4 cells. Would they have fungal resistance if they used a tiny amount of ketoconazole in a shampoo or gel? I would love to see a reference on that,Wikipedia has a reference on your comment. http://en.wikipedia.org/wiki/Ketoconazole Regards, VergelPoWeRUSA.orgFrom: Barrow <barrowster@...> Sent: Wed, September 15, 2010 12:10:03 PMSubject: Re: Hair loss"I developed this product but the manufacturer closed down, so I am looking for a "I think the use of an antifungal as a baldness treatment is quite misguided. Ketoconazole resistance in the community is already a problem; this can only worsen it, more rapidly.JB

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JBNizoral shampoo and hair gels contain less than 10 mg of ketoconazole per dose, which is NOT ingested orally. The penetration of that ketoconazole is minimal into the blood stream and it is mostly uptaken by hair follicles. To extrapolate the statement that you pasted to the transdermal use is a big jump. No lowering of free testosterone happens at that tiny transdermal dose. And besides, only 30% of that tiny dose is uptaken.Believe me, I will never take anything that lowers my testosterone! Regards, VergelPoWeRUSA.orgFrom: Barrow <barrowster@...> Vergel <nelsonvergel@...>Cc: Sent: Wed, September 15, 2010 5:25:13 PMSubject: Re: Re: Hair loss

"As an antiandrogen, ketoconazole operates through at least two mechanisms of action. First, and most notably, high oral doses of ketoconazole (e.g. 400 mg 3x/day) block both testicular and adrenal androgen biosynthesis, leading to a reduction in circulating testosterone levels.[15] Ketoconazole produces this effect through inhibition of cytochrome P450 and 17,20-lyase, which are involved in the synthesis and degradation of steroids, including the precursors of testosterone. Due to its efficacy at reducing systemic androgen levels, ketoconazole has been used as a treatment for androgen-dependent prostate cancer.[16] Second, ketoconazole is an androgen receptor antagonist, competing with androgens such as testosterone and DHT for androgen receptor binding. This effect is thought to be quite weak, even with high oral doses of ketoconazole.[17]"Just like Proscar, but more........On Sep 15, 2010, at 6:07 PM, Vergel wrote:JBInteresting observation, although your term "misguided" is assuming resistance that develops to trandermal exposure of ketoconazole.I talked to the makers of Nizoral shampoo and they have not had any reports of ketoconazole resistance. But of course, they may not have a lot of immune compromised patients. I have used it for 10 years with no problems. I have had no fungal infections at all. And I have 200 CD4 cells. I have had no occurrence of Candida. It is hard to say what would happen in a person with detectable HIV viral load with under 100 CD4 cells. Would they have fungal resistance if they

used a tiny amount of ketoconazole in a shampoo or gel? I would love to see a reference on that,Wikipedia has a reference on your comment. http://en.wikipedia.org/wiki/Ketoconazole Regards, VergelPoWeRUSA.orgFrom: Barrow <barrowster@...> Sent: Wed, September 15, 2010 12:10:03 PMSubject: Re: Hair loss"I developed this product but the manufacturer closed down, so I am looking for a "I think the use of an antifungal as a baldness treatment is quite misguided. Ketoconazole resistance in the community is already a problem; this can only worsen it, more rapidly.JB

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If you are a man with MPB, you need to lower DHT levels inside of the

hair follicles or you will most assuredly lose your hair. The best drug

for doing just that is Avodart. That may not be the case for women

though.

>

>

> HAIR LOSS

> _http://www.drlwilson.com/ARTICLES/HAIR%20LOSS.htm_

> (http://www.drlwilson.com/ARTICLES/HAIR%20LOSS.htm)

> by Lawrence , MD

>

> Hair loss affects at least one fourth of the population, and probably

more

> like half. It is a very annoying and disfiguring, especially for

women,

> who often suffer from it beginning around age 30 or so. Nutritional

> balancing may often help this condition. The following imbalances

are associated

> with hair loss. As they are corrected, many clients report that

their hair

> loss has stopped or at least slowed significantly. In most cases,

the

> hair grows back in if the problem has begun in the past year or two.

>

>

> NUTRIENT DEFICIENCIES

>

>

> Hair is called a soft tissue, and is also considered a connective

tissue

> of the body. It is similar in composition to skin, fingernails,

toenails

> and other connective tissue. These tissues require many nutrients,

> particularly B-complex vitamins, vitamins C and E, sulfur, calcium,

magnesium, zinc,

> bioavailable copper and others.

>

>

> Those with hair loss should first make sure they are getting plenty

of

> general good nutrition. This is best accomplished by taking a

> multi-vitamin-mineral product and by eating animal protein daily such

as meats, eggs, and

> preferably raw or organic dairy products. The other important food

group

> is plenty of cooked vegetables each day. Eat at least two large

servings of

> cooked vegetables.

>

>

> Raw vegetables. Sadly, these do not provide as many minerals, in our

> experience, because most people cannot thoroughly digest raw food.

The

> minerals are locked in the fibrous vegetable matter and it passes

through one

> undigested. Also, raw food of all types is too yin. Read more about

this

> situation in the article entitled _Raw Food_

> (http://www.drlwilson.com/ARTICLES/Raw%20Food192.htm) .

>

>

> A YIN CONDITION OF THE BODY

>

>

> An observation is that most women and some men with hair loss are in

a

> very yin condition of the body chemistry. Yin means cold and

expanded in

> Chinese medical terminology and in macrobiotics. If, for example,

the hair

> shaft is slightly loose in the follicle, the hair may fall out much

easier

> than if the follicle were more yang.

>

>

> A yang rising condition is definitely associated with hair loss. A

> variant of a yin condition of the body is called in acupuncture terms

yang

> rising. It occurs when the body is very yin, usually with a low

thyroid

> condition, and then it reacts by trying to become more yang, but in a

half-hearted

> or inadequate manner.

>

> This pattern is revealed easily on a properly performed hair mineral

> analysis. We call it a four highs pattern. It occurs when four

macrominerals †"

> calcium, magnesium, sodium and potassium †" are all above their

ideal

> levels. This interesting mineral pattern and acupuncture tendency is

discussed

> more in an article on this website entitled _Four Highs Pattern_

> (http://www.drlwilson.com/ARTICLES/four%20high%20electrolytes.htm) .

>

>

> How to make the body more yang. To do this quickly, one needs to eat

more

> cooked vegetables, with some cooked meats, and soft cooked eggs.

These

> are more yang foods.

>

> Also, it is necessary to avoid yin foods, such as all sweets, all

sugars,

> and most if not all raw food. One must avoid most fruit and all

fruit

> juices and other yin beverages such as alcohol, soda pop and

sweetened tea.

>

> We find, for example, that many women with hair loss eat a lot of

fruit

> and salads, both of which are very yin in macrobiotic terms. Many

have been

> or still are leaning toward vegetarian diets as well. This can

contribute

> to hair loss in some cases.

>

> To make the body more yang one should also be careful not to take too

many

> vitamins and mineral supplements as all are yin to some degree. Even

> herbs or homeopathic remedies are quite yin and should be minimized

as well.

> Most are even more yin than raw food, for example.

>

>

> Sauna therapy and coffee enemas. To improve the yin/yang balance of

the

> body much faster, add the use of a near infrared sauna daily and do

one or

> two coffee enemas daily. Coffee enemas are better than colonic

irrigation to

> make the body more yang. We do not recommend drinking coffee,

although

> one cup of regular coffee is okay.

>

>

> COPPER AND THYROID IMBALANCES

>

>

> Most women and men who are losing their hair have a copper imbalance.

> Copper is absolutely required for connective tissue integrity, which

includes

> the proper structure and function of the hair. Often those with hair

loss

> have symptoms of copper imbalance such as varicose veins, migraines

or

> other headaches, PMS, mood swings or others. Vegetarian diets are

also known

> to worsen copper imbalances.

>

>

> Copper and the thyroid. Medical science knows well that a low

thyroid

> causes dry, brittle and usually falling hair. Copper is just one

factor that

> can cause a low thyroid. Most with hair loss have a low thyroid

condition,

> even though the T3, T4 and TSH levels may appear normal in the blood

serum.

>

> On hair mineral analyses, a low thyroid is revealed by a slow

oxidation

> rate, and more specifically by an elevated calcium/potassium ratio.

This

> indicates a low thyroid effect, even if the levels of thyroid

hormones are

> normal. In other words, one may have plenty of thyroid hormones, but

they are

> not acting at a cellular level in the proper way. For some reason,

the

> hormones are less effective. This very confusing topic is discussed

in

> detail in an article on this website entitled _Thyroid Imbalances_

> (http://www.drlwilson.com/ARTICLES/thyroid.htm) .

>

> Other reasons for thyroid imbalance include low iodine, high mercury,

> other toxic metals in the body, or high levels of the iodine

antagonists †"

> bromine, fluorine and chlorine.

>

>

> DEHYDRATION

>

>

> Some with hair loss simply are dehydrated. This is quite common.

Adults

> usually need 3 quarts of drinking water every day or sometimes more

in warm

> or dry climates, or if one is physically active.

>

> Some people drink the wrong kind of water †" usually reverse

osmosis water,

> also called drinking water or purified water. Most often, this does

not

> hydrate the body well enough, and this can contribute to hair loss.

>

> Other people drink enough spring water or carbon-filtered tap water,

but

> they drink coffee, caffeinated tea, soda pop, other caffeinated foods

or

> beverages, sweet juices or alcohol. All of these dehydrate the body

badly.

> These do not count as part of the three quarts daily of pure water

that

> everyone needs. In fact, they should be minimized since they can

cause

> dehydration.

>

>

> IMPAIRED CIRCULATION INVOLVING THE SCALP

>

>

> A more unusual cause of hair loss is impaired circulation to the

scalp.

> One might have arteriosclerosis of the arteries leading to the head

or

> scalp, for example. Perhaps more of the blood reaching the head is

needed

> inside the brain, so less may go to the hair follicles, which then

may suffer

> malnutrition and toxin buildup as a result.

>

> Tension in the fascia or even the muscles of the neck might also

> contribute to hair loss by interfering a little with circulation to

the scalp.

> Massaging the scalp might help in these cases, and is a good idea

anyway when

> one is taking a shower, for instance.

>

> Often a nutritional balancing program will help with generalized

tension

> in the neck and back, and will slowly reverse arteriosclerosis and

> atherosclerosis if that has set in.

>

>

> CALCIUM OR OTHER TOXIC DEPOSITS IN THE HAIR FOLLICLES

>

>

> Another imbalance seen on a few hair mineral analyses is a buildup of

what

> is called metastatic or biounavailable calcium in the soft tissues of

the

> body, which includes the skin and hair follicles. This could also

cause

> dysfunction of the hair follicles and hair loss.

>

> At times, other toxins will affect the scalp. These might be due to

a

> skin care product such as a shampoo, hair dye or other product that

is

> somewhat toxic. Other causes are iron, manganese or other chemicals

in the water

> used for bathing and drinking. This cause for hair loss requires

stopping

> the use of the toxic product, and perhaps filtering the bathing water

if it

> is toxic, which is not common.

>

>

> A COMPLETE NUTRITIONAL BALANCING PROGRAM IS BEST

>

>

> While you can try making the changes above, the best procedure is

usually

> to begin a complete nutritional balancing program. The reason for

this is

> that many causes for hair loss, including hidden copper toxicity, are

quite

> deep. They will not be revealed on any medical or holistic test, and

must

> be slowly uncovered or unwound over a period of months or longer.

>

> In order to do this, we recommend a nutritional balancing program

based

> upon a properly performed and correctly interpreted hair mineral

analysis.

> This is the only way I know of to correctly monitor progress and make

sure

> that you are moving in the right direction.

>

>

>

>

>

>

>

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