Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 I take this to keep my DHEA up in the normal range. Dr. did say if you take to much of this it will covert to estrogen. I think he said not to take more then 25 mgs a day. http://www.myvitanet.com/dhea260capph.html Phil Dave <daultman@...> wrote: Can't DHEA convert to estrogen? Mine was low, but Dr told me not to supplement because of e conversion... > Re: high DHEA > > >You are just lucky your body is making it and working dam good. Phil > >wildfoxhunter <wildfoxhunter@...> wrote: >What could make DHEA go up if one is not taking a DHEA supplement? > >My DHEA was high before starting 500iu hCG QD, and remained high after >taking it. What could make it read high, regardless of whether there >is high or low testosterone measured in the same blood sample? > >Could it be some conversion enzyme is lacking? > >WF > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 From what I have researched, DHEA has a high propensity to convert to estrogen. philip georgian <pmgamer18@...> wrote:I take this to keep my DHEA up in the normal range. Dr. did say if you take to much of this it will covert to estrogen. I think he said not to take more then 25 mgs a day. http://www.myvitanet.com/dhea260capph.html Phil Dave <daultman@...> wrote: Can't DHEA convert to estrogen? Mine was low, but Dr told me not to supplement because of e conversion... > Re: high DHEA > > >You are just lucky your body is making it and working dam good. Phil > >wildfoxhunter <wildfoxhunter@...> wrote: >What could make DHEA go up if one is not taking a DHEA supplement? > >My DHEA was high before starting 500iu hCG QD, and remained high after >taking it. What could make it read high, regardless of whether there >is high or low testosterone measured in the same blood sample? > >Could it be some conversion enzyme is lacking? > >WF > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 Works fabuously at what? What symptoms did it cure for her, or what benefits does she now see from it? > Re: high DHEA > > >My wife has been taking DHEA 25 mg. daily for well over a year >now. Works fabulously. > >Ron > >betaine_hcl <no_reply > wrote: > >I tried oral DHEA when I was younger it seemed to help >libido but now all it does is make my breasts itch. >If one took DHEA trandermally as opposed to orally >it would be a better route. I supposely had dose >titrated by DHEA tests which were 150 dollars a pop. >It took 75 mgs orally to raise much. I could tell >the Doc did not like the dose!! No comment though. >He didn't test estrogens >again like he should have. And that dose just made >my breast itch and seemed to irritant the prostate. >That adventure cost me in excess of 800 dollars and likely >over 1000. Later, I trimmed the dose to 50 then 25 then 0. > >DHEA maybe better for women? > > > >> >What could make DHEA go up if one is not taking a DHEA supplement? >> > >> >My DHEA was high before starting 500iu hCG QD, and remained high >after >> >taking it. What could make it read high, regardless of whether >there >> >is high or low testosterone measured in the same blood sample? >> > >> >Could it be some conversion enzyme is lacking? >> > >> >WF >> > >> > >> > >> > >> > >> > >> > >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 does getting your DHEA up to mid range help with Low T issues? what'st the link between the two (DHEA and total T)? philip georgian <pmgamer18@...> wrote:For me that is to low I take this and it has me up to 315 range 80 to 560 ug/dL on a test of DHEA-SO4. http://www.myvitanet.com/dhea260capph.html I take it just before I eat lunch. Her is a link on it. http://www.diagnose-me.com/cond/C11446.html Phil Jack <rockin813@...> wrote: what function does DHEA play? my levels are 159 (range 80-569). is that considered normal? philip georgian <pmgamer18@...> wrote: You are just lucky your body is making it and working dam good. Phil wildfoxhunter <wildfoxhunter@...> wrote: What could make DHEA go up if one is not taking a DHEA supplement? My DHEA was high before starting 500iu hCG QD, and remained high after taking it. What could make it read high, regardless of whether there is high or low testosterone measured in the same blood sample? Could it be some conversion enzyme is lacking? WF Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 When women use DHEA it converts into Testosterone and if she was low that is what made her feel better. Phil Dave <daultman@...> wrote: Works fabuously at what? What symptoms did it cure for her, or what benefits does she now see from it? > Re: high DHEA > > >My wife has been taking DHEA 25 mg. daily for well over a year >now. Works fabulously. > >Ron > >betaine_hcl <no_reply > wrote: > >I tried oral DHEA when I was younger it seemed to help >libido but now all it does is make my breasts itch. >If one took DHEA trandermally as opposed to orally >it would be a better route. I supposely had dose >titrated by DHEA tests which were 150 dollars a pop. >It took 75 mgs orally to raise much. I could tell >the Doc did not like the dose!! No comment though. >He didn't test estrogens >again like he should have. And that dose just made >my breast itch and seemed to irritant the prostate. >That adventure cost me in excess of 800 dollars and likely >over 1000. Later, I trimmed the dose to 50 then 25 then 0. > >DHEA maybe better for women? > > > >> >What could make DHEA go up if one is not taking a DHEA supplement? >> > >> >My DHEA was high before starting 500iu hCG QD, and remained high >after >> >taking it. What could make it read high, regardless of whether >there >> >is high or low testosterone measured in the same blood sample? >> > >> >Could it be some conversion enzyme is lacking? >> > >> >WF >> > >> > >> > >> > >> > >> > >> > >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 i take it this stuff is non-prescription. i didn't realize DHEA was linked to T levels. I'll go ahead and purchase this stuff as it's the only level that is considered low in lab given ranges. all my other stuff is right around the median for lab ranges given with exception of LH (slightly on the higher side but well within range). Thanks for your post. philip georgian <pmgamer18@...> wrote: For me that is to low I take this and it has me up to 315 range 80 to 560 ug/dL on a test of DHEA-SO4. http://www.myvitanet.com/dhea260capph.html I take it just before I eat lunch. Her is a link on it. http://www.diagnose-me.com/cond/C11446.html Phil Jack <rockin813@...> wrote: what function does DHEA play? my levels are 159 (range 80-569). is that considered normal? philip georgian <pmgamer18@...> wrote: You are just lucky your body is making it and working dam good. Phil wildfoxhunter <wildfoxhunter@...> wrote: What could make DHEA go up if one is not taking a DHEA supplement? My DHEA was high before starting 500iu hCG QD, and remained high after taking it. What could make it read high, regardless of whether there is high or low testosterone measured in the same blood sample? Could it be some conversion enzyme is lacking? WF Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 Not for me my levels stayed the same but my fatigue got better. Phil Jack <rockin813@...> wrote: does getting your DHEA up to mid range help with Low T issues? what'st the link between the two (DHEA and total T)? philip georgian <pmgamer18@...> wrote:For me that is to low I take this and it has me up to 315 range 80 to 560 ug/dL on a test of DHEA-SO4. http://www.myvitanet.com/dhea260capph.html I take it just before I eat lunch. Her is a link on it. http://www.diagnose-me.com/cond/C11446.html Phil Jack <rockin813@...> wrote: what function does DHEA play? my levels are 159 (range 80-569). is that considered normal? philip georgian <pmgamer18@...> wrote: You are just lucky your body is making it and working dam good. Phil wildfoxhunter <wildfoxhunter@...> wrote: What could make DHEA go up if one is not taking a DHEA supplement? My DHEA was high before starting 500iu hCG QD, and remained high after taking it. What could make it read high, regardless of whether there is high or low testosterone measured in the same blood sample? Could it be some conversion enzyme is lacking? WF Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 DHEA is a precursor hormone, the body converts it to any of several different hormones, including testosterone AND estrogen. The book ADRENAL FATIGUE has a pretty good description of this...and also how testosterone is made in the adrenal glands as well as the testicles. > Re: high DHEA > > >i take it this stuff is non-prescription. i didn't realize >DHEA was linked to T levels. I'll go ahead and purchase this >stuff as it's the only level that is considered low in lab >given ranges. all my other stuff is right around the median >for lab ranges given with exception of LH (slightly on the >higher side but well within range). > >Thanks for your post. > > >philip georgian <pmgamer18@...> wrote: >For me that is to low I take this and it has me up to 315 >range 80 to 560 ug/dL on a test of DHEA-SO4. >http://www.myvitanet.com/dhea260capph.html >I take it just before I eat lunch. >Her is a link on it. http://www.diagnose-me.com/cond/C11446.html >Phil > >Jack <rockin813@...> wrote: >what function does DHEA play? my levels are 159 (range >80-569). is that considered normal? > > >philip georgian <pmgamer18@...> wrote: >You are just lucky your body is making it and working dam good. Phil > >wildfoxhunter <wildfoxhunter@...> wrote: >What could make DHEA go up if one is not taking a DHEA supplement? > >My DHEA was high before starting 500iu hCG QD, and remained high after >taking it. What could make it read high, regardless of whether there >is high or low testosterone measured in the same blood sample? > >Could it be some conversion enzyme is lacking? > >WF > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 If your primary and go on HCG your adrenal glands will make T. Phil Dave <daultman@...> wrote: DHEA is a precursor hormone, the body converts it to any of several different hormones, including testosterone AND estrogen. The book ADRENAL FATIGUE has a pretty good description of this...and also how testosterone is made in the adrenal glands as well as the testicles. > Re: high DHEA > > >i take it this stuff is non-prescription. i didn't realize >DHEA was linked to T levels. I'll go ahead and purchase this >stuff as it's the only level that is considered low in lab >given ranges. all my other stuff is right around the median >for lab ranges given with exception of LH (slightly on the >higher side but well within range). > >Thanks for your post. > > >philip georgian <pmgamer18@...> wrote: >For me that is to low I take this and it has me up to 315 >range 80 to 560 ug/dL on a test of DHEA-SO4. >http://www.myvitanet.com/dhea260capph.html >I take it just before I eat lunch. >Her is a link on it. http://www.diagnose-me.com/cond/C11446.html >Phil > >Jack <rockin813@...> wrote: >what function does DHEA play? my levels are 159 (range >80-569). is that considered normal? > > >philip georgian <pmgamer18@...> wrote: >You are just lucky your body is making it and working dam good. Phil > >wildfoxhunter <wildfoxhunter@...> wrote: >What could make DHEA go up if one is not taking a DHEA supplement? > >My DHEA was high before starting 500iu hCG QD, and remained high after >taking it. What could make it read high, regardless of whether there >is high or low testosterone measured in the same blood sample? > >Could it be some conversion enzyme is lacking? > >WF > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 7, 2005 Report Share Posted November 7, 2005 Remember the bioavailability of oral DHEA is a mere 3% which means that you are actually getting only 3/4 of a mg from that 25mg capsule that you are swallowing. If you take the powder from that gelcap and mix it with lotion or petroleum jelly and rub it into your skin, you are likely to get 8mg of this androgen. The transdermal absorption rate is 33%. A lot of other factors can effect DHEA levels besides direct DHEA supplementation. Hormones morph into one another constantly (intracrinology). The excerpt below from a recent study of hormone blood level measurements elaborates on this. I have a larger portion of the text from this study on my web page (finally finished) about the unreliability of blood level hormone testing at http://infowoman.freewebpage.org/HormoneTests.html (This webpage explains our prevailing belief in the futility of hormone tests as a guide for determining my husband's optimal dose of Letrozole (aromatase inhibitor) in answer to those who recommended testing. BTW he's doing much better. Obviously E2 levels are on the rise. (Perhaps by now probably back up too high.) Fatigue has diminished and libido and erectile function restored. Next week he plans to resume the therapy at a greatly reduced dose. Will post again as to progress. The excerpt about DHEA levels: " Traditionally, circulating hormone levels have been used as the main indicators of tissue exposure. However, intracrinology plays a pivotal role in androgen metabolism, such that the active androgens exert their effects in the same cells in which they are synthesized, without release into the pericellular compartment. DHEA and DHEAS are converted in extragonadal target tissues, such as the brain, bone, and adipose, either to androstenedione or testosterone that may then be aromatized to estrone or estradiol or converted by 5-reductase to dihydrotestosterone in the same cells. Thus androgenic effects vary according to individual variations in the amount and activity of the enzymes 5-reductase and aromatase, and individual differences in the androgen-receptor response. " Circulating Androgen Levels and Self-reported Sexual Function in Women R. , MD, PhD; L. on, MD; Donath, MA; Robin J. Bell, MD, PhD JAMA. 2005;294:91-96. Access via PURCHASE ACCESS Vol. 294 No. 1, July 6, 2005 http://jama.ama- assn.org/cgi/content/full/294/1/91 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 Just as a side note - wouldn't taking DHEA in an oral form be similar to taking T orally? Drake > > Remember the bioavailability of oral DHEA is a mere 3% which means > that you are actually getting only 3/4 of a mg from that 25mg capsule > that you are swallowing. > > If you take the powder from that gelcap and mix it with lotion or > petroleum jelly and rub it into your skin, you are likely to get 8mg > of this androgen. The transdermal absorption rate is 33%. > > A lot of other factors can effect DHEA levels besides direct DHEA > supplementation. Hormones morph into one another constantly > (intracrinology). > > The excerpt below from a recent study of hormone blood level > measurements elaborates on this. > > I have a larger portion of the text from this study on my web page > (finally finished) about the unreliability of blood level hormone > testing at > http://infowoman.freewebpage.org/HormoneTests.html > (This webpage explains our prevailing belief in the futility of > hormone tests as a guide for determining my husband's optimal dose of > Letrozole (aromatase inhibitor) in answer to those who recommended > testing. > > BTW he's doing much better. Obviously E2 levels are on the rise. > (Perhaps by now probably back up too high.) Fatigue has diminished > and libido and erectile function restored. Next week he plans to > resume the therapy at a greatly reduced dose. Will post again as to > progress. > > The excerpt about DHEA levels: > " Traditionally, circulating hormone levels have been used as the main > indicators of tissue exposure. However, intracrinology plays a > pivotal role in androgen metabolism, such that the active androgens > exert their effects in the same cells in which they are synthesized, > without release into the pericellular compartment. DHEA and DHEAS are > converted in extragonadal target tissues, such as the brain, bone, > and adipose, either to androstenedione or testosterone that may then > be aromatized to estrone or estradiol or converted by 5-reductase to > dihydrotestosterone in the same cells. Thus androgenic effects vary > according to individual variations in the amount and activity of the > enzymes 5-reductase and aromatase, and individual differences in the > androgen-receptor response. " > > Circulating Androgen Levels and Self-reported Sexual Function in > Women > R. , MD, PhD; L. on, MD; Donath, MA; > Robin J. Bell, MD, PhD > JAMA. 2005;294:91-96. Access via PURCHASE ACCESS > Vol. 294 No. 1, July 6, 2005 http://jama.ama- > assn.org/cgi/content/full/294/1/91 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 i went to GNC and saw the DHEA vitamins...25mg time release. the guy behind the counter is taking them. he says it converts to T and has a positive effect for him. he's 40 ish years old..no T levels checked but knows he's declining as he ages. i bought some vitamins and will be taking them. i wonder if i should take separate from the TRT..maybe give this stuff a try first for a week or so to see if there's a positive effect...and if not, than continue with the TRT. reason being is my testes are currently producting T..just not at high levels as i want. philip georgian <pmgamer18@...> wrote: Not for me my levels stayed the same but my fatigue got better. Phil Jack <rockin813@...> wrote: does getting your DHEA up to mid range help with Low T issues? what'st the link between the two (DHEA and total T)? philip georgian <pmgamer18@...> wrote:For me that is to low I take this and it has me up to 315 range 80 to 560 ug/dL on a test of DHEA-SO4. http://www.myvitanet.com/dhea260capph.html I take it just before I eat lunch. Her is a link on it. http://www.diagnose-me.com/cond/C11446.html Phil Jack <rockin813@...> wrote: what function does DHEA play? my levels are 159 (range 80-569). is that considered normal? philip georgian <pmgamer18@...> wrote: You are just lucky your body is making it and working dam good. Phil wildfoxhunter <wildfoxhunter@...> wrote: What could make DHEA go up if one is not taking a DHEA supplement? My DHEA was high before starting 500iu hCG QD, and remained high after taking it. What could make it read high, regardless of whether there is high or low testosterone measured in the same blood sample? Could it be some conversion enzyme is lacking? WF Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 > > i went to GNC and saw the DHEA vitamins...25mg time release. the guy behind the counter is taking them. he says it converts to T and has a positive effect for him. he's 40 ish years old..no T levels checked but knows he's declining as he ages. i bought some vitamins and will be taking them. i wonder if i should take separate from the TRT..maybe give this stuff a try first for a week or so to see if there's a positive effect...and if not, than continue with the TRT. reason being is my testes are currently producting T..just not at high levels as i want. > If you discontinue t, use the time to get diagnostic tests (primary vs secondary). I wouldn't try to rely on DHEA as a substitute for trt. There is a big difference between " can convert " and " does convert " . Testosterone is made from cholesterol. Having high cholesterol doesn't necessarily mean you have high testosterone. At this point you don't know what testosterone levels will even be needed to address your symptoms. Brad Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 > > Just as a side note - > > wouldn't taking DHEA in an oral form be similar to taking T orally? > > Drake > hmm. Not exactly. Taking oral DHEA did boost my DHEA-S rather effectively. Taking unmodified t orally doesn't boost your t levels effectively because the liver metabolizes the t on first pass. A huge dose might work. Brad Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 good point brad. thanks for the info. i guess like Phil, i can do both the DHEA and TRT. it shouldn't hurt...and my E2 readings are 17 after week of TRT..while my DHT is 300pts over the max (range 100 - 550)...can care less about the MPB. in my earlier posts i mentioned i was back to normal...and that was after 10 days of TRT..i discontinued though cuz i felt bloated....and then 2 days later i started feeling so good and felt good for abou a week before getting back to before the TRT...i should've stuck with it and let my body get adjusted to it and wait the bloated feeling out. i guess i'll do both for a while and go from there. dhea vitamins can't hurt..and im only doing the 50mg Testim (5g tube of Testim1%). thanks again for posts. brad999us <no_reply > wrote: > > i went to GNC and saw the DHEA vitamins...25mg time release. the guy behind the counter is taking them. he says it converts to T and has a positive effect for him. he's 40 ish years old..no T levels checked but knows he's declining as he ages. i bought some vitamins and will be taking them. i wonder if i should take separate from the TRT..maybe give this stuff a try first for a week or so to see if there's a positive effect...and if not, than continue with the TRT. reason being is my testes are currently producting T..just not at high levels as i want. > If you discontinue t, use the time to get diagnostic tests (primary vs secondary). I wouldn't try to rely on DHEA as a substitute for trt. There is a big difference between " can convert " and " does convert " . Testosterone is made from cholesterol. Having high cholesterol doesn't necessarily mean you have high testosterone. At this point you don't know what testosterone levels will even be needed to address your symptoms. Brad Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 So HCG will stimulate the adrenals as well as the testes (when secondary)? Just want to make sure I read that right. WF > > If your primary and go on HCG your adrenal glands will make T. > Phil Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 Bingo again to Phil! Ron philip georgian <pmgamer18@...> wrote: When women use DHEA it converts into Testosterone and if she was low that is what made her feel better. Phil Dave <daultman@...> wrote: Works fabuously at what? What symptoms did it cure for her, or what benefits does she now see from it? > Re: high DHEA > > >My wife has been taking DHEA 25 mg. daily for well over a year >now. Works fabulously. > >Ron > >betaine_hcl <no_reply > wrote: > >I tried oral DHEA when I was younger it seemed to help >libido but now all it does is make my breasts itch. >If one took DHEA trandermally as opposed to orally >it would be a better route. I supposely had dose >titrated by DHEA tests which were 150 dollars a pop. >It took 75 mgs orally to raise much. I could tell >the Doc did not like the dose!! No comment though. >He didn't test estrogens >again like he should have. And that dose just made >my breast itch and seemed to irritant the prostate. >That adventure cost me in excess of 800 dollars and likely >over 1000. Later, I trimmed the dose to 50 then 25 then 0. > >DHEA maybe better for women? > > > >> >What could make DHEA go up if one is not taking a DHEA supplement? >> > >> >My DHEA was high before starting 500iu hCG QD, and remained high >after >> >taking it. What could make it read high, regardless of whether >there >> >is high or low testosterone measured in the same blood sample? >> > >> >Could it be some conversion enzyme is lacking? >> > >> >WF >> > >> > >> > >> > >> > >> > >> > >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 Well this guy is miss informed taking DHEA will not make ones T go up much worth measuring. It will make a womens T go up but not a mans. Phil Jack <rockin813@...> wrote: i went to GNC and saw the DHEA vitamins...25mg time release. the guy behind the counter is taking them. he says it converts to T and has a positive effect for him. he's 40 ish years old..no T levels checked but knows he's declining as he ages. i bought some vitamins and will be taking them. i wonder if i should take separate from the TRT..maybe give this stuff a try first for a week or so to see if there's a positive effect...and if not, than continue with the TRT. reason being is my testes are currently producting T..just not at high levels as i want. philip georgian <pmgamer18@...> wrote: Not for me my levels stayed the same but my fatigue got better. Phil Jack <rockin813@...> wrote: does getting your DHEA up to mid range help with Low T issues? what'st the link between the two (DHEA and total T)? philip georgian <pmgamer18@...> wrote:For me that is to low I take this and it has me up to 315 range 80 to 560 ug/dL on a test of DHEA-SO4. http://www.myvitanet.com/dhea260capph.html I take it just before I eat lunch. Her is a link on it. http://www.diagnose-me.com/cond/C11446.html Phil Jack <rockin813@...> wrote: what function does DHEA play? my levels are 159 (range 80-569). is that considered normal? philip georgian <pmgamer18@...> wrote: You are just lucky your body is making it and working dam good. Phil wildfoxhunter <wildfoxhunter@...> wrote: What could make DHEA go up if one is not taking a DHEA supplement? My DHEA was high before starting 500iu hCG QD, and remained high after taking it. What could make it read high, regardless of whether there is high or low testosterone measured in the same blood sample? Could it be some conversion enzyme is lacking? WF Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 HCG will activate cells we don't know about as per Dr. . Phil wildfoxhunter <wildfoxhunter@...> wrote: So HCG will stimulate the adrenals as well as the testes (when secondary)? Just want to make sure I read that right. WF > > If your primary and go on HCG your adrenal glands will make T. > Phil Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 Why?? I am wondering because I bought some DHEA and find that I get irritable taking just the .25mg time released. Is that due to DHT production or what? I didn't feel better on it I felt achy all over. TIA Svario --------------------------------- FareChase - Search multiple travel sites in one click. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2005 Report Share Posted November 8, 2005 I can't say I hope you stoped taking it. Phil Savario <savario2000@...> wrote: Why?? I am wondering because I bought some DHEA and find that I get irritable taking just the .25mg time released. Is that due to DHT production or what? I didn't feel better on it I felt achy all over. TIA Svario --------------------------------- FareChase - Search multiple travel sites in one click. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2005 Report Share Posted November 9, 2005 Yeah I stopped taking it. --------------------------------- FareChase - Search multiple travel sites in one click. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2005 Report Share Posted November 9, 2005 The 3% oral bioavailability figure for DHEA that is touted about on different websites is apparently taken from a 1996 rat study (I've copied the abstract below). ---- Thank you . The absorption rates from this study are also cited by other researchers, and given my abysmal past experience with oral hormones, I have been more than willing to accept these numbers. You are certainly correct about the research in your paragraph below. In studies of hypogonadal men and older persons of mixed gender with hormonal deficiencies, the DHEA was indeed administered orally. A good collection of studies is found in this document: http://www.ccjm.org/PDFFILES/Olech11_05.pdf -----There are at least a half-dozen other actual human studies that show that a 25-50mg oral dose of DHEA gives a very significant increase in DHEA and (more importantly) DHEA-S levels, increasing levels from low normal (and even from well below normal in 's patients) to at least mid-range. So obviously, oral bioavailability is reasonable. In humans, oral bioavailability is probably more on the order of 10 times 3%, or 30%.----- Also the effects that men on this forum have reported from oral doses of DHEA cannot be a fluke. Certainly thyroid replacement hormone works via oral administration. And while I am fond of stating that oral E & P HRT did not work for me and does not work for many others, the truth is that it produced a marginal decrease of hot flashes. So perhaps I needed my mindset shaken. I am still not going to embrace the oral administration of sex hormones. The risk factor from cancer, liver damage and other ills has to be magnified by the oral route as well as the larger doses needed to work. I'm more comfortable with a vaginal daily dose of 5mg DHEA than the 25mg or 125 mg that I might need to swallow to achieve the same effect. But I will concede that oral DHEA probably works better than I have been insisting. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2011 Report Share Posted April 30, 2011 Many thanks Sheila. I'll have a look at those webpages. The Cortisol Levels were: Sample 1 @ 8am = 11.9 (Range 12-22) Low Sample 2 @ 12pm = 16.9 (Range 5.0-9.0)High Sample 3 @ 5pm = 36.5 (Range 3.0-7.0) Contaminated! Sample 4 @ 11pm = 1.9 (Range 1.0-3.0) Normal Sample 3 was contaminated. At the time I wondered why there were little tiny flecks of brown in it, then I remembered much later that I'd eaten a small crispy cake a couple of hours before, and this is still in some teeth. Nevermind! I don't seem to have any problems with the Thyroid. The doctor didn't seem to worry at my results. But I'll give them to you anyway: T4 = 133.0 (R 58-154) TSH = 1.05 (R 0.4-4.0) FT4 = 16.1 (R 10-22) FT3 = 5.58 (R 2.8-6.5) FT4:FT3 Ratio = 2.9 (R 2.0-4.5) RT3 = 0.57 (R 0.14-0.54) High TG = 20.0 (R 0-40) TPO = 10 (R 0-35) The only thing there was a high RT3. So I'm not on any Thyroid meds and I haven't seen an Endo. either, as we never thought it was needed. Many thanks for your time again Sheila. It's always much appreciated. > > , we need the reference ranges for each of the cortisol tests done - > at 8.00a.m. - 12 Noon, 4.00p.m. and again at midnight. Can you send us these > please and what the results were for each of those times. Why was the sample > contaminated? > > Are you seeing an endocrinologist? If you Google DHEA you will find a lot of > references to thyroid problems, adrenal diseases and Cushing's. I doubt that > low iron is a cause of your high DHEA. There is really no way to diagnose > outside of a good doctor. Have you recently started her thyroid meds? You > can get high DHEA when adjusting the medication or when taking too high a > dose. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 1, 2011 Report Share Posted May 1, 2011 Hi , Your cortisol levels overall don't look bad, apart from the contaminated one..... maybe some Nutri adrenal extra would help to get it all regulated..... The dhea is produced by both the adrenal glands and the ovaries... apparantly high levels can point towards insulin resistance and high stress..... (I just did a google search)... Maybe with NAX it will all calm down? What is worrying is the high level of reverse t3. If you have too much reverse t3 compared with free t3 i.e a ratio of less than 20... (yours is 9.7) then the body is making too much reverse t3 and breaking down the T4, when it should be converting the t4 into t3. The problem with this situation is that the reverse t3 stops the cells from using the free t3, so you get hypothyroid symptoms, and in fact are hypothyroid, although the T4 and T3 look ok. Usually the advice is to take t3 only and stop T4 until it is all out of the system and there is nothing to cause the reverse t3 to be manufactured. But... if you aren't taking any meds then you can't stop taking t4. It may be that you aren't converting the t4 into t3 because of lack of selenium? How do you feel? I'm assuming you feel tired and weary which is why you have had the tests...... Are you taking plenty of Vitamin C? How are your Ferritin, Folate, Iron, B12 Magnesium and D3 levels? They can all affect thyroid conversion and uptake.... It's a matter of placing all the pieces of the puzzle together.... something, somewhere isn't optimal.... you just have to work out what it is..... > > > I don't seem to have any problems with the Thyroid. The doctor didn't seem to worry at my results. But I'll give them to you anyway: > > T4 = 133.0 (R 58-154) > TSH = 1.05 (R 0.4-4.0) > FT4 = 16.1 (R 10-22) > FT3 = 5.58 (R 2.8-6.5) > FT4:FT3 Ratio = 2.9 (R 2.0-4.5) > RT3 = 0.57 (R 0.14-0.54) High > TG = 20.0 (R 0-40) > TPO = 10 (R 0-35) > > The only thing there was a high RT3. Quote Link to comment Share on other sites More sharing options...
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