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Re: Continuous Afib-What next?

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Guy,

The doctors in Cleveland were probably referring to the RACE and AFFIRM

studies/trials that were released earlier this year. You might benefit from

reading the studies, which I found at www.cardiologyonline.com

I too am in continuous afib, and would like to not be in afib, but feel okay and

do everything I did before. I'm on small dosages of Digoxin and Diltiazem to

control the rate and Coumadin to keep the INR between 2.0 and 2.5. If I need a

little pain reliever (like for dental issues) it seems that Tylenol is

preferred.

The individual taking both Aspirin and Coumadin may be doing okay if the INR is

watched closely for coagulation. I can't remember where, but it seems to me

there was a study that indicated no advantage to taking both aspirin and

warfarin. It also seems to be that the risk of digestive system problems is

greater with the aspirin.

Harry (WI)

PS Thanks to all for expressing their opinions and experiences

Re: Continuous Afib-What next?

In a message dated 10/15/2002 1:48:01 PM Central Daylight Time,

john.codling@... writes:

> Guy its here already Doeftilide Tiklosyan in the uSA..

>

> C Uk

>

>

I know about dofetilide but am not familiar with tiklosyan. Is this just

a longer name for dofetilide? I have not chosen to try dofetilide because of

the 3 day stay in the hospital and my concern that if the intake is that

critical then wouldn't metabolism and variations in renal function cause dose

related problems?

Thanks Guy

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Guy,

The doctors in Cleveland were probably referring to the RACE and AFFIRM

studies/trials that were released earlier this year. You might benefit from

reading the studies, which I found at www.cardiologyonline.com

I too am in continuous afib, and would like to not be in afib, but feel okay and

do everything I did before. I'm on small dosages of Digoxin and Diltiazem to

control the rate and Coumadin to keep the INR between 2.0 and 2.5. If I need a

little pain reliever (like for dental issues) it seems that Tylenol is

preferred.

The individual taking both Aspirin and Coumadin may be doing okay if the INR is

watched closely for coagulation. I can't remember where, but it seems to me

there was a study that indicated no advantage to taking both aspirin and

warfarin. It also seems to be that the risk of digestive system problems is

greater with the aspirin.

Harry (WI)

PS Thanks to all for expressing their opinions and experiences

Re: Continuous Afib-What next?

In a message dated 10/15/2002 1:48:01 PM Central Daylight Time,

john.codling@... writes:

> Guy its here already Doeftilide Tiklosyan in the uSA..

>

> C Uk

>

>

I know about dofetilide but am not familiar with tiklosyan. Is this just

a longer name for dofetilide? I have not chosen to try dofetilide because of

the 3 day stay in the hospital and my concern that if the intake is that

critical then wouldn't metabolism and variations in renal function cause dose

related problems?

Thanks Guy

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I was just reading about the surprise of using coumadin and aspirin therapy.

There have been trials going on which will have crept into usage which show

that certain people benefit on lower dosages of the two because of their

different actions on thinning blood. I can't remember where the results were

but if I find a link I will post it.

Fran

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I was just reading about the surprise of using coumadin and aspirin therapy.

There have been trials going on which will have crept into usage which show

that certain people benefit on lower dosages of the two because of their

different actions on thinning blood. I can't remember where the results were

but if I find a link I will post it.

Fran

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>Hi and , I took the combination of Coumadin and Aspirin

because I was highly resistant to Coumadin.....Since it took about

5 or more weeks for my INR to be in the therapeutic level of 2-

3.....The doc felt if the Coumadin was not yet effective, the

aspirin could protect me. For the last three weeks I am no longer

taking aspirin, and also since my INR level was above 3 (it is

3.7) I gave blood, that helped to thin it also, these were mini

phlebs of l50ml to ease the strain on my heart. I gave blood because

in no way was I going to have an electrical cardioversion with my

hemoglobin at 48. Please keep in mind that I had a high hematocrit

(48) and that made my blood especially thick and prone to blood

clots. Before the procedure I also cut out all vegetables except

carrots, corn, tomatoes and iceberg lettuce because I wanted keep my

consumption of Vitamin K to a minimum. My hematocrit is below 42

now, so my I hope my blood viscosity is good....as long as I

remember to hydrate...I tend to go without drinking water sometimes

a little too long...ergo my blood is thicker and more viscous as a

result. I hope that helps to clarify the issue. Regards,Isabelle.

>

> snip........ is right. It's the combination - Aspirin and

Coumadin - that

> arose my curiosity. Have you ever come across information why a

> patient would be taking both??

>

> /

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>Hi and , I took the combination of Coumadin and Aspirin

because I was highly resistant to Coumadin.....Since it took about

5 or more weeks for my INR to be in the therapeutic level of 2-

3.....The doc felt if the Coumadin was not yet effective, the

aspirin could protect me. For the last three weeks I am no longer

taking aspirin, and also since my INR level was above 3 (it is

3.7) I gave blood, that helped to thin it also, these were mini

phlebs of l50ml to ease the strain on my heart. I gave blood because

in no way was I going to have an electrical cardioversion with my

hemoglobin at 48. Please keep in mind that I had a high hematocrit

(48) and that made my blood especially thick and prone to blood

clots. Before the procedure I also cut out all vegetables except

carrots, corn, tomatoes and iceberg lettuce because I wanted keep my

consumption of Vitamin K to a minimum. My hematocrit is below 42

now, so my I hope my blood viscosity is good....as long as I

remember to hydrate...I tend to go without drinking water sometimes

a little too long...ergo my blood is thicker and more viscous as a

result. I hope that helps to clarify the issue. Regards,Isabelle.

>

> snip........ is right. It's the combination - Aspirin and

Coumadin - that

> arose my curiosity. Have you ever come across information why a

> patient would be taking both??

>

> /

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>Correction to my previous post:Please note that my hemoglobin was

l6 and my hematocrit was 48.( the ratio is about 1 to 3) Now, my

hemoglobin is l3 and my hematocrit is below 39. Isabelle

> >

Hi and , I took the combination of Coumadin and Aspirin

> because I was highly resistant to Coumadin.....

snip........ is right. It's the combination - Aspirin and

> Coumadin - that

> > arose my curiosity...... > > /

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>Correction to my previous post:Please note that my hemoglobin was

l6 and my hematocrit was 48.( the ratio is about 1 to 3) Now, my

hemoglobin is l3 and my hematocrit is below 39. Isabelle

> >

Hi and , I took the combination of Coumadin and Aspirin

> because I was highly resistant to Coumadin.....

snip........ is right. It's the combination - Aspirin and

> Coumadin - that

> > arose my curiosity...... > > /

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In a message dated 10/17/02 11:04:55 AM Central Daylight Time, manning@...

writes:

> Guy,

>

> The doctors in Cleveland were probably referring to the RACE and AFFIRM

> studies/trials that were released earlier this year. You might benefit

> from reading the studies, which I found at www.cardiologyonline.com

>

>

Harry,

Those were the reports the Cleveland Doctors were refering to. I believe I

have read parts of them.

Guy

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In a message dated 10/17/02 11:04:55 AM Central Daylight Time, manning@...

writes:

> Guy,

>

> The doctors in Cleveland were probably referring to the RACE and AFFIRM

> studies/trials that were released earlier this year. You might benefit

> from reading the studies, which I found at www.cardiologyonline.com

>

>

Harry,

Those were the reports the Cleveland Doctors were refering to. I believe I

have read parts of them.

Guy

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In a message dated 10/17/02 12:41:09 PM Central Daylight Time,

B6426@... writes:

> << The individual taking both Aspirin and Coumadin may be doing okay if the

> INR is watched closely for coagulation. >>

>

> I don't believe the INR reflects the aspirin effect on coagulation since

> aspirin affects a different part of the coagulation system (the platelets)

> than does Coumadin. Coumadin affects the Vitamin K dependent factors.

> Brenta

>

>

I think this is right. So you would be without either clotting assistance and

enhance the chance for uncontrollable bleeding.

Guy

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Isabelle writes: Brenta and Guy: Your information is pertinent and

quite accurate for the majority of people.....but please remember

that I had borderline iron overload with my hgb being l6 and hmt

48.....and sometimes I also put myself on a regime of therapeutic

phlebotomies(give blood)....There is as you well know a fine line

between meds, phlebs,and eating certain foods to thin the blood

(garlic,ginger,ginseng,pineapple,cucumber) and not over thinning

blood. I watch my INR closely and I still clot very fast even

though my INR is above 3....They keep me as of last Tues. two days

a week on Coumadin 7.5mg and l0mg the other days.> I look forward to

a reduction and by next week there may be another reduction since my

hgb will be below l3 and my hmt will be below 39 and my INR may be

higher. These figures are only applicable to me because of

iod......The general concensus for good health is that most women

should be at l4 and 42 and most men should be at l5 and 45 hgb and

hmt respectively. If you have heart disease these levels or somewhat

lower may be very beneficial...in preventing blood clots in addition

to meds. Did not snip because info below is important to know.

>Brenta writes: > << The individual taking both Aspirin and Coumadin

may be doing okay if the

> > INR is watched closely for coagulation. I don't believe the INR

reflects the aspirin effect on coagulation since aspirin affects a

different part of the coagulation system (the platelets)> than does

Coumadin. Coumadin affects the Vitamin K dependent factors.

Brenta, I think this is right. So you would be without either

clotting assistance and enhance the chance for uncontrollable

bleeding.

> Guy

>

>

>

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Isabelle writes: Brenta and Guy: Your information is pertinent and

quite accurate for the majority of people.....but please remember

that I had borderline iron overload with my hgb being l6 and hmt

48.....and sometimes I also put myself on a regime of therapeutic

phlebotomies(give blood)....There is as you well know a fine line

between meds, phlebs,and eating certain foods to thin the blood

(garlic,ginger,ginseng,pineapple,cucumber) and not over thinning

blood. I watch my INR closely and I still clot very fast even

though my INR is above 3....They keep me as of last Tues. two days

a week on Coumadin 7.5mg and l0mg the other days.> I look forward to

a reduction and by next week there may be another reduction since my

hgb will be below l3 and my hmt will be below 39 and my INR may be

higher. These figures are only applicable to me because of

iod......The general concensus for good health is that most women

should be at l4 and 42 and most men should be at l5 and 45 hgb and

hmt respectively. If you have heart disease these levels or somewhat

lower may be very beneficial...in preventing blood clots in addition

to meds. Did not snip because info below is important to know.

>Brenta writes: > << The individual taking both Aspirin and Coumadin

may be doing okay if the

> > INR is watched closely for coagulation. I don't believe the INR

reflects the aspirin effect on coagulation since aspirin affects a

different part of the coagulation system (the platelets)> than does

Coumadin. Coumadin affects the Vitamin K dependent factors.

Brenta, I think this is right. So you would be without either

clotting assistance and enhance the chance for uncontrollable

bleeding.

> Guy

>

>

>

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fuzzyturtle2002 wrote:

> I would appreciate any ideas you might have for me.I am in afib all

> the time. Sotalol was tried without success. Thencardioversion-no

> luck. Now back to atenolol, coumadin, and aspirin. On hold right now

> getting some EP opinions.What do you think? Thanks from fuzzy

>

>

> Have you tried Flecainide (Tambocor)?

Have you considered Pulmonary Vein Ablation (Focal Catheter

Ablation)? It's a low risk procedure with a high success rate.

A-FibFriend Steve

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fuzzyturtle2002 wrote:

> I would appreciate any ideas you might have for me.I am in afib all

> the time. Sotalol was tried without success. Thencardioversion-no

> luck. Now back to atenolol, coumadin, and aspirin. On hold right now

> getting some EP opinions.What do you think? Thanks from fuzzy

>

>

> Have you tried Flecainide (Tambocor)?

Have you considered Pulmonary Vein Ablation (Focal Catheter

Ablation)? It's a low risk procedure with a high success rate.

A-FibFriend Steve

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fuzzyturtle2002 wrote:

> I would appreciate any ideas you might have for me.I am in afib all

> the time. Sotalol was tried without success. Thencardioversion-no

> luck. Now back to atenolol, coumadin, and aspirin. On hold right now

> getting some EP opinions.What do you think? Thanks from fuzzy

>

>

> Have you tried Flecainide (Tambocor)?

Have you considered Pulmonary Vein Ablation (Focal Catheter

Ablation)? It's a low risk procedure with a high success rate.

A-FibFriend Steve

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Isn't it more common to try the available medications then move on to

ablations than the other way around?

> Have you tried Flecainide (Tambocor)?

Have you considered Pulmonary Vein Ablation (Focal Catheter

Ablation)? It's a low risk procedure with a high success rate.

A-FibFriend Steve

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