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Re: Continuous Afib-What next?

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In a message dated 10/15/2002 9:53:15 AM Central Daylight Time,

turtlezero@... writes:

> I would appreciate any ideas you might have for me.I am in afib all the

> time. Sotalol was tried without success. Thencardioversion-no luck. Now

> back to atenolol, coumadin, and aspirin. On hold right now getting some EP

> opinions.What do you think? Thanks from fuzzy

>

Two cardiologists at the Cleveland Clinic told me that rate control

(atenolol) and " blood thiners " (coumadin) are just as effective as far as

mortality is concerned as rythem control. So if a person is comfortable in

afib the choice of treatment is a wash. I am relatively comfortable in afib

but feel I have more energy and endurance in nsr so I am trying to stay in

nsr for now useing amiodarone. My plan is too stop using it at the first sign

of serious side effects. I hope new drugs with less side effects come along

by then.

Guy in Iowa

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In a message dated 10/15/2002 9:53:15 AM Central Daylight Time,

turtlezero@... writes:

> I would appreciate any ideas you might have for me.I am in afib all the

> time. Sotalol was tried without success. Thencardioversion-no luck. Now

> back to atenolol, coumadin, and aspirin. On hold right now getting some EP

> opinions.What do you think? Thanks from fuzzy

>

Two cardiologists at the Cleveland Clinic told me that rate control

(atenolol) and " blood thiners " (coumadin) are just as effective as far as

mortality is concerned as rythem control. So if a person is comfortable in

afib the choice of treatment is a wash. I am relatively comfortable in afib

but feel I have more energy and endurance in nsr so I am trying to stay in

nsr for now useing amiodarone. My plan is too stop using it at the first sign

of serious side effects. I hope new drugs with less side effects come along

by then.

Guy in Iowa

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In a message dated 10/15/2002 1:48:01 PM Central Daylight Time,

john.codling@... writes:

> Guy its here already Doeftilide Tiklosyan in the uSA..

>

> C Uk

>

>

I know about dofetilide but am not familiar with tiklosyan. Is this just

a longer name for dofetilide? I have not chosen to try dofetilide because of

the 3 day stay in the hospital and my concern that if the intake is that

critical then wouldn't metabolism and variations in renal function cause dose

related problems?

Thanks Guy

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In a message dated 10/15/2002 1:48:01 PM Central Daylight Time,

john.codling@... writes:

> Guy its here already Doeftilide Tiklosyan in the uSA..

>

> C Uk

>

>

I know about dofetilide but am not familiar with tiklosyan. Is this just

a longer name for dofetilide? I have not chosen to try dofetilide because of

the 3 day stay in the hospital and my concern that if the intake is that

critical then wouldn't metabolism and variations in renal function cause dose

related problems?

Thanks Guy

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Guy its here already Doeftilide Tiklosyan in the uSA..

C Uk

In a message dated 10/15/2002 9:53:15 AM Central Daylight Time,

turtlezero@... writes:

> I would appreciate any ideas you might have for me.I am in afib all the

> time. Sotalol was tried without success. Thencardioversion-no luck. Now

> back to atenolol, coumadin, and aspirin. On hold right now getting some EP

> opinions.What do you think? Thanks from fuzzy

>

Two cardiologists at the Cleveland Clinic told me that rate control

(atenolol) and " blood thiners " (coumadin) are just as effective as far as

mortality is concerned as rythem control. So if a person is comfortable in

afib the choice of treatment is a wash. I am relatively comfortable in afib

but feel I have more energy and endurance in nsr so I am trying to stay in

nsr for now useing amiodarone. My plan is too stop using it at the first sign

of serious side effects. I hope new drugs with less side effects come along

by then.

Guy in Iowa

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Guy its here already Doeftilide Tiklosyan in the uSA..

C Uk

In a message dated 10/15/2002 9:53:15 AM Central Daylight Time,

turtlezero@... writes:

> I would appreciate any ideas you might have for me.I am in afib all the

> time. Sotalol was tried without success. Thencardioversion-no luck. Now

> back to atenolol, coumadin, and aspirin. On hold right now getting some EP

> opinions.What do you think? Thanks from fuzzy

>

Two cardiologists at the Cleveland Clinic told me that rate control

(atenolol) and " blood thiners " (coumadin) are just as effective as far as

mortality is concerned as rythem control. So if a person is comfortable in

afib the choice of treatment is a wash. I am relatively comfortable in afib

but feel I have more energy and endurance in nsr so I am trying to stay in

nsr for now useing amiodarone. My plan is too stop using it at the first sign

of serious side effects. I hope new drugs with less side effects come along

by then.

Guy in Iowa

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Hi Fuzzy:

I was in permanent Afib for years. Various meds and cardioversions were

unsuccessful. Then along came Dofetilide/Tikoysyn - and after the second dose I

was finally in NSR. Except for four episodes in two years, I have remained in

NSR.

http://www.pfizer.com/hml/know/knowtikosyn.html

This is one of many sites pertaining to Dofetilide in our *Link* section under

*Medications....check em out!

http://groups.yahoo.com/group/AFIBsupport/links

Ellen

(NSR on Dofetilide)

****************************************

----- Original Message -----

From: fuzzyturtle2002

I would appreciate any ideas you might have for me.I am in afib all the time.

Sotalol was tried without success. (snip) Fuzzy

*****************

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In a message dated 10/15/2002 3:16:10 PM Pacific Daylight Time,

guygooch@... writes:

<< I know about dofetilide but am not familiar with tiklosyan. Is this

just

a longer name for dofetilide? >>

Dofetilide and Tikosyn are one and the same drug.

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In a message dated 10/15/2002 3:16:10 PM Pacific Daylight Time,

guygooch@... writes:

<< I know about dofetilide but am not familiar with tiklosyan. Is this

just

a longer name for dofetilide? >>

Dofetilide and Tikosyn are one and the same drug.

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same drug not sure if i have the spelling right though.

> Re: Continuous Afib-What next?

>

> In a message dated 10/15/2002 3:16:10 PM Pacific Daylight Time,

> guygooch@... writes:

>

> << I know about dofetilide but am not familiar with tiklosyan. Is this

> just

> a longer name for dofetilide? >>

>

> Dofetilide and Tikosyn are one and the same drug.

>

>

> Web Page - http://groups.yahoo.com/group/AFIBsupport

> FAQ - http://groups.yahoo.com/group/AFIBsupport/files/Administrative/faq.htm

> For more information: http://www.dialsolutions.com/af

> Unsubscribe: AFIBsupport-unsubscribe

> List owner: AFIBsupport-owner

> For help on how to use the group, including how to drive it via email,

> send a blank email to AFIBsupport-help

>

> Nothing in this message should be considered as medical advice, or should be

acted upon without consultation with one's physician.

>

>

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same drug not sure if i have the spelling right though.

> Re: Continuous Afib-What next?

>

> In a message dated 10/15/2002 3:16:10 PM Pacific Daylight Time,

> guygooch@... writes:

>

> << I know about dofetilide but am not familiar with tiklosyan. Is this

> just

> a longer name for dofetilide? >>

>

> Dofetilide and Tikosyn are one and the same drug.

>

>

> Web Page - http://groups.yahoo.com/group/AFIBsupport

> FAQ - http://groups.yahoo.com/group/AFIBsupport/files/Administrative/faq.htm

> For more information: http://www.dialsolutions.com/af

> Unsubscribe: AFIBsupport-unsubscribe

> List owner: AFIBsupport-owner

> For help on how to use the group, including how to drive it via email,

> send a blank email to AFIBsupport-help

>

> Nothing in this message should be considered as medical advice, or should be

acted upon without consultation with one's physician.

>

>

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Hi Fuzzy,

This is the kind of afib I am dealing with also. Sorry, I dont have

an answer, I too am searching for the " elusive " cure. But I do have

a question: Why coumadin and aspirin? What dose of coumadin are you

taking? Would appreciate a response.

/

> Now back to atenolol, coumadin, and aspirin. On hold right now

getting some EP opinions.What do you think? Thanks from fuzzy

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Hi , are you asking why patients with AF should be taking Aspirin or

Wafarin?

If I am correct then the reason is when in AF and especially when in paroxysmal

AF your heart kick in and out of AF. This may cause clots to develop in the

Atria, when the heart goes back to NSR it could kick the clot out into the

system and cause a stroke. It is felt that patients with AF should be put onto

this type of therapy to prevent a stroke.

In the UK this is the first line in treatment in AF. In the USA I am not so

sure.

Best regards

C

PS I met a guy on the maze board who was the British Judo coach and because of

the sport he would not take either of the above because of bruising and bleeds.

He had a Few minior strokes that left him with no sight in his left eye and one

hand useless. I think this is better to be safe than sorry.

> This is the kind of afib I am dealing with also. Sorry, I dont have

> an answer, I too am searching for the " elusive " cure. But I do have

> a question: Why coumadin and aspirin? What dose of coumadin are you

> taking? Would appreciate a response.

>

> /

>

>

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If you are not the intended recipient, please advise the sender immediately

by reply e-mail and delete this message and any attachments

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In a message dated 10/16/2002 7:22:30 AM Pacific Daylight Time,

john.codling@... writes:

<< , are you asking why patients with AF should be taking Aspirin or

Wafarin?

>>

I think was asking if he is taking aspirin along with Coumadin. I would

ask the same question because I think that's rather unusual. My doctor told

me when I started taking Coumadin that I must discontinue all aspirin because

it would intensify the anticoagulant effect of the Coumadin. He approved of

Tylenol, which I then switched to for headaches and other pain. However, his

nurse told me that even Tylenol has a degree of blood thinning effect, but

not as great as that of aspirin.

in sinus in Seattle (Day 147)

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In a message dated 10/16/2002 7:22:30 AM Pacific Daylight Time,

john.codling@... writes:

<< , are you asking why patients with AF should be taking Aspirin or

Wafarin?

>>

I think was asking if he is taking aspirin along with Coumadin. I would

ask the same question because I think that's rather unusual. My doctor told

me when I started taking Coumadin that I must discontinue all aspirin because

it would intensify the anticoagulant effect of the Coumadin. He approved of

Tylenol, which I then switched to for headaches and other pain. However, his

nurse told me that even Tylenol has a degree of blood thinning effect, but

not as great as that of aspirin.

in sinus in Seattle (Day 147)

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In a message dated 10/16/2002 7:22:30 AM Pacific Daylight Time,

john.codling@... writes:

<< , are you asking why patients with AF should be taking Aspirin or

Wafarin?

>>

I think was asking if he is taking aspirin along with Coumadin. I would

ask the same question because I think that's rather unusual. My doctor told

me when I started taking Coumadin that I must discontinue all aspirin because

it would intensify the anticoagulant effect of the Coumadin. He approved of

Tylenol, which I then switched to for headaches and other pain. However, his

nurse told me that even Tylenol has a degree of blood thinning effect, but

not as great as that of aspirin.

in sinus in Seattle (Day 147)

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For the group( requested more info)My EP has me on 50mg atenolol twice a

day, a regular aspirin in theAM, and 5 mg coumadin in the evening. I had a heart

attack in 1996and was put on atenolol and aspirin. Then when the afib started

afew months later the coumadin was started. Thanks from Fuzzy

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For the group( requested more info)My EP has me on 50mg atenolol twice a

day, a regular aspirin in theAM, and 5 mg coumadin in the evening. I had a heart

attack in 1996and was put on atenolol and aspirin. Then when the afib started

afew months later the coumadin was started. Thanks from Fuzzy

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For the group( requested more info)My EP has me on 50mg atenolol twice a

day, a regular aspirin in theAM, and 5 mg coumadin in the evening. I had a heart

attack in 1996and was put on atenolol and aspirin. Then when the afib started

afew months later the coumadin was started. Thanks from Fuzzy

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Thanks, Fuzzy, for the details. It is a rather unusual combination.

Did your doc ever explain to you what the advantages are of combining

Aspirin and Coumadin?

For a few days (because of tendinitis) I have been adding as many as

2 Ibuprofins daily with my docs approval. Short term he was not

concerned.

I assume, you still go for regular P/T tests, aiming for an INR

between 2 and 3?

/

> For the group( requested more info)My EP has me on 50mg

atenolol twice a day, a regular aspirin in theAM, and 5 mg coumadin

in the evening. I had a heart attack in 1996and was put on atenolol

and aspirin. Then when the afib started afew months later the

coumadin was started. Thanks from Fuzzy

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Hi ,

is right. It's the combination - Aspirin and Coumadin - that

arose my curiosity. Have you ever come across information why a

patient would be taking both??

/

>

> Hi , are you asking why patients with AF should be taking

Aspirin or Wafarin?

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<< The individual taking both Aspirin and Coumadin may be doing okay if the

INR is watched closely for coagulation. >>

I don't believe the INR reflects the aspirin effect on coagulation since

aspirin affects a different part of the coagulation system (the platelets)

than does Coumadin. Coumadin affects the Vitamin K dependent factors.

Brenta

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<< The individual taking both Aspirin and Coumadin may be doing okay if the

INR is watched closely for coagulation. >>

I don't believe the INR reflects the aspirin effect on coagulation since

aspirin affects a different part of the coagulation system (the platelets)

than does Coumadin. Coumadin affects the Vitamin K dependent factors.

Brenta

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