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Re: Milk Thistle

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At 03:01 PM 12/4/2002 -0500, you wrote:

>how does milk thistle interfere with Kaletra absorption?

It probably doesn't since the ritonavir improves the lopinavir

absorption. We don't know beyond one small study by Piscitelli which

showed a decline in trough indinavir levels in HIV-Negative volunteers

taking monotherapy IDV. The authors did not feel that this was a clinically

significant finding--i.e., the effect won't impair the ability of IDV to

work (esp. in the context of a cocktail).

But we don't know. Currently, a study of MT in HIV-HCV coinfected people is

being proposed--maybe we'll get some answers. In the meantime, MT may help

if your liver enzymes or histology are out of whack (or if you're

glutathione is low but it is hard to know if that is the case).

I think the modest risk of an effect on PI/ARV level is outweighed by the

potential benefit for improving liver function. I think if I had to take

ARV and with my HCV, I'd take milk thistle.

M.

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At 11:33 AM 12/4/2002 -0800, you wrote:

>You're aware I assume that Milk Thistle interferes with the levels of

>Kaletra and other PI's in the blood.

>( Assuming of course that you are on PI's)

Oh--just saw this. What are you basing this on? The Piscitelli data? Or the

in vitro data? Or is there something new?

M.

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At 01:40 PM 12/4/2002 -0800, you wrote:

>I do not the exact science behind it, but my Doctor ( Julio Montaner )

>tested my blood and drug levels in my blood throughout the day at three

>hour intervals for an entire 12 hour period. There was overwhelming

>evidence that after ingesting Milk Thistle the amount of Kaletra in my

>blood became ( to quote my Doctor here ) " Dangerously Low " .

>He retested my blood again the same way without the Milk Thistle ( about a

>month later ) ( I had stopped the Milk Thistle for this entire period)

>The Kaletra was absorbed properly and showed normal and effective levels

>in my blood.

>Interesting enough, my T4's starting rising soon after I discontinued the

>Milk Thistle.

Ah! Now that is interesting and disturbing news. Sadly, it's also the

single best way for each person to find out what works and what does

not--statistics don't mean squat after all. It's your blood/body that

counts first.

In general, for others, tho, this serves as a cautionary tale!!

M.

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I am taking Agenerase, Trizivir and Viread.

Supplements: I am also taking

Milk Thisle

5THP

multivitamins

Niacin(no flush) 500mg.

CoQ10

L-Carnitine 2x500mg

Any ideas / warnings?

Thanks JL

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  • 8 months later...

Can anyone recommend a reputable brand of milk thistle? There are so

many different brands on the market that it makes selection difficult.

Does anyone know if the Solgar brand is any good?

What are the side effects (if any) that I should watch out for when

taking milk thistle?

Solgar is good. Anything made by Jarrow Formulas is also we trust.

Vergel

Director, Program for Wellness Restoration (PoWeR)

An all volunteer non profit 501 © 3 organization

www.medibolics.com

www.facialwasting.org

www.atac-usa.org

Subscribe to a free lipodystrophy email list by sending an email to:

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At 01:05 PM 8/13/2003 +0000, you wrote:

>Can anyone recommend a reputable brand of milk thistle? There are so

>many different brands on the market that it makes selection difficult.

>Does anyone know if the Solgar brand is any good?

>What are the side effects (if any) that I should watch out for when

>taking milk thistle?

I'd recommend you start milk thistle on the same day you get bloodwork.

Another study in HIV-negative volunteers found no serious effect of milk

thistle on indinavir levels. This suggests it should not mess with your

antivirals but we don't know.

Happily, it looks like FIAR will have its first clinical study starting

soon, looking at milk thistle in people with HIV and hep C. The study will

be taking place at Mt. Sinai in New York.

As to side effects, they are pretty rare. Gastrointestinal effects may

occur; they're usually pretty mild. Rash can occur in some people. Nausea

and vomiting have been reported--but these are all very rare occurrences.

Still, forewarned is forearmed. It has been tested in many clinical

settings and found to be extremely well tolerated.

For brands, a good question. I do not know about the Solgar brand for sure.

Thistlyn has been used in a variety of tests and may be one of the best.

Made by Nature's Way. Other good companies that I think are reputable

include Thorne Research, Phytopharmica, Pacific Biologics, Herb Pharm--but

I'm not sure if they make milk thistle that's easily obtainable. I have

used the Solgar brand and it seems OK. Consumerlabs has not yet done a test

of milk thistle so far.

Once the study gets its FDA IND cleared, we'll be underway and a more

formal announcement will go out. When we do, we'll be testing the batch and

lot independently to assure identity, potency and purity. Meantime, we have

to wait for the GMP rulemaking to become effective, however, I think a lot

of the companies are trying to do a decent job.

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Make sure you are not on protease inhibitors when you take milk thistle as this supplement has been clinically shown to drastically reduce PI inhibitors in the blood.

Re: Milk Thistle

Can anyone recommend a reputable brand of milk thistle? There are so many different brands on the market that it makes selection difficult.Does anyone know if the Solgar brand is any good?What are the side effects (if any) that I should watch out for when taking milk thistle?Solgar is good. Anything made by Jarrow Formulas is also we trust. VergelDirector, Program for Wellness Restoration (PoWeR)An all volunteer non profit 501 © 3 organizationwww.medibolics.comwww.facialwasting.orgwww.atac-usa.orgSubscribe to a free lipodystrophy email list by sending an email to:lipodystrophy-subscribe

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  • 2 years later...
Guest guest

I tried replying to this before, but for some reason it never

posted.

The South American herbs sound really incredible. Is it good for

general hypoglycemia? I wonder what the plants are?

Thanks for all the info. Hope you had a good weekend and are well.

Still looking forward to receiving your cookbook.

Aloha, L

>

>

>

> I do like the whole form of a herb is possible as well as teas.

Certain

> herbs like dandelion, dandelion leaf, nettle, cleavers etc I prefer

as

> teas. The tourble sometimes is administration - and I don't drink

that

> much liquid - still it is energy too not just quantity. Using

tablets

> and powders, and capsules (I am not a tincture fan though some are -

I

> don't like the alcohol or the glycerine though some herbs are more

> soluable that way or aspects of them are more soluable in alcohol

than

> water) is more isolated but also more potent for some conditons or

when

> you want a fast and replicable effect. The bigger the front the

bigger

> the back. you do have to be more aware of interactions, medication,

> condition and also the cumulative effect of what the individial is

> taking. one herb on its own may not be too yin or too yang but if

taking

> severel....

>

> Another herb that seems to work well as a tea is a blend of two

south

> american herbs - called Milagor De Sal Selva which I have been

drinking

> - it has phenomenol effects for type 2 diabetes and although I have

type

> 1 and dont notice immediate beenfits it has some general protective

> qualities - and I really like it now - it has kind of the taste of

> cloves without any heat at all mixed with the taste of good bancha.

> Really nice!

>

> I have heard there is a new more bioavailable form of Milk Thistle -

> Purecaps make it as well as some other companies. I am really

impressed

> by their quality

>

>

> Ilanit

>

> --------------------------------------------------------------------

----

>

> Little Tree Pty Limited, Melbourne, Australia (Little Tree). ®

> registered trademark, © copyright 2003. All rights reserved. This

email

> message and attachments may contain information that is

confidential to

> Little Tree. If you are not the intended recipient you cannot use,

> distribute, forward or copy the message or attachments. In such a

case,

> please notify the sender by return email and erase all copies of

the

> message and attachments. The sender of this email message does not

allow

> the recipient to forward this email message or attachments in whole

or

> in part by means of the internet. Opinions, conclusions and other

> information in this message and attachments that do not relate to

the

> official business of Little Ttree are neither given nor endorsed by

it.

> This email message and any attachments are subject to copyright.

>

>

>

> Ms Ilanit Tof

> B.A. (Psychophysiology/Psychology)

> Advanced Diploma Healing with Wholefoods

> PhD Holistic Nutrition (candidate)

>

> Little Tree Oriental Healing Arts

> Helping you grow to new heights of wellbeing

> with Oriental Traditions and Modern Nutrition

>

> ilanit@...

> www.littletree.com.au

> <http://www.littletree.com.au>

> <http://www.littletree.com.au> <http://www.littletree.com.au>

> <http://www.littletree.com.au>

>

> --------------------------------------------------------------------

----

>

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Guest guest

leslieanneashburn wrote:

I tried

replying to this before, but for some reason it never

posted.

The South American herbs sound really incredible. Is it good for

general hypoglycemia? I wonder what the plants are?

they are listed on some of the websites if you search for Milagor de la

selva.

I think one is for the liver and one for the pancreas but they have

systemic effects. the look like bark. now when I have bancha, I almost

wish it was Milagro de la selva.

there is quite a spefic way to boil it for ten minutes then steep

overnight.

I am not familiar with the individual herbs but know that it is said

that there is a "cure" for everything in the rainforest of the amazon!

Ilanit Tof - Signature

Ilanit

Ms Ilanit Tof

B.A. (Psychophysiology/Psychology)

Advanced Diploma Healing with Wholefoods

PhD Holistic Nutrition (candidate)

Little Tree Oriental Healing Arts

Helping you grow to new heights of wellbeing

with Oriental Traditions and Modern Nutrition

ilanit@...

www.littletree.com.au

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Guest guest

We just finished a great Healing Earth film series here at the

University of Hawaii. It featured alternative modes of healing from

all over the world, including Hawaii. Some of what we saw was about

the curanderas from Mexico and South America. (I just realized that

Milagro de la Selva means Miracle from the Jungle.)

One movie showed about the indigenous community in the jungles of

Peru and some of their incredible herbs. I loved how the researcher

traveling and studying the healing herbs and the culture of the

medicine men only created documentation for them to keep in their own

language, so that it would not be exploited by wealthier nations. He

took a lot of flack about not publishing the results in peer reviewed

journals, but he didn't care!

There is a company called Amazon Rain Forest that sells things like

vitamins, supplements, chocolate, and tea using these herbs. Their

skin care line seems really pure and nice, but it's a network

marketing system which I'm not quite so fond of.

I have been to the Ecuadorian Amazon rainforest. It's really

incredible.

>

> > I tried replying to this before, but for some reason it never

> > posted.

> >

> > The South American herbs sound really incredible. Is it good for

> > general hypoglycemia? I wonder what the plants are?

>

>

> they are listed on some of the websites if you search for Milagor

de la

> selva.

>

> I think one is for the liver and one for the pancreas but they have

> systemic effects. the look like bark. now when I have bancha, I

almost

> wish it was Milagro de la selva.

>

> there is quite a spefic way to boil it for ten minutes then steep

overnight.

>

> I am not familiar with the individual herbs but know that it is

said

> that there is a " cure " for everything in the rainforest of the

amazon!

>

> >

>

> Ilanit

>

> --------------------------------------------------------------------

----

>

> Little Tree Pty Limited, Melbourne, Australia (Little Tree). ®

> registered trademark, © copyright 2003. All rights reserved. This

email

> message and attachments may contain information that is

confidential to

> Little Tree. If you are not the intended recipient you cannot use,

> distribute, forward or copy the message or attachments. In such a

case,

> please notify the sender by return email and erase all copies of

the

> message and attachments. The sender of this email message does not

allow

> the recipient to forward this email message or attachments in whole

or

> in part by means of the internet. Opinions, conclusions and other

> information in this message and attachments that do not relate to

the

> official business of Little Ttree are neither given nor endorsed by

it.

> This email message and any attachments are subject to copyright.

>

>

>

> Ms Ilanit Tof

> B.A. (Psychophysiology/Psychology)

> Advanced Diploma Healing with Wholefoods

> PhD Holistic Nutrition (candidate)

>

> Little Tree Oriental Healing Arts

> Helping you grow to new heights of wellbeing

> with Oriental Traditions and Modern Nutrition

>

> ilanit@...

> www.littletree.com.au

> <http://www.littletree.com.au>

> <http://www.littletree.com.au> <http://www.littletree.com.au>

> <http://www.littletree.com.au>

>

> --------------------------------------------------------------------

----

>

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