Infection with Hepatitis C Virus Genotype 4 in the United States

[Guest guest]

thank you for posting this info, andy. Blessings, Satya

[ ] Infection with hepatitis C virus genotype 4 in the United States

Infection with hepatitis C virus genotype 4 in the United States JOURNAL OF CLINICAL GASTROENTEROLOGY. JAN 2004; 38 (1) : 68-71 Lyra, AC; Ramrakhiani, S; Bacon, BR; Di-Bisceglie, AM Background: Hepatitis C virus genotype differences seem to be ofconsiderable clinical significance because they affect responses toantiviral therapy. HCV genotype 4 is rare in the United Sates and there arefew published data regarding response to therapy in patients with HCVgenotype 4 infection. Objectives: To assess epidemiologic factors associated with HCVgenotype 4 infection in United States and to describe the response rate totherapy with the combination of alpha interferon and ribavirin. Methods: All hepatologists in our Division were asked for informationabout patients they had treated with HCV genotype 4. In addition, wesearched the computer database from Saint Louis University Hospital in thelast 40 months (1999 to 2002). Twenty HCV genotype 4 patients wereidentified. A retrospective chart review was performed to collectinformation about their demographics, risk factors for acquisition ofinfection, baseline laboratory studies and response to antiviral therapy. Results: A risk factor for exposure to HCV was noted in 14 cases(70%); 12 patients had a history of illicit drug use, whereas a history ofblood transfusion was detected in three cases; I patient had both riskfactors. Only 4 of 20 individuals had fibrosis stage 3 or 4 on liverbiopsy. Seventeen patients were treated, 14 of whom completed therapy; 10patients were sustained responders. Conclusions: As with other HCV genotypes, most patients with HCVgenotype 4 in the United States acquire the infection through intravenousdrug use, liver disease is often mild to moderate in severity and 59% ofour patients had a sustained virologic response after combination therapywith interferon and ribavirin.

[Guest guest]

At 10:54 AM 01/15/2004, thecelestialspirit wrote:

>some may also be resistant to posting articles because if some here don't

>agree with each word, you will be challenged endlessly and your post

>picked apart to shreds.

Satya you seem to be unable to grasp the concept of a discussion group is

to discuss. What better to discuss than the articles posted?

> That can make it unpleasant to post.

Your too personally attached to your posts.

> noticed a couple people who hardly ever post, did so last week, and were

> shot down immediately. One was scolded for posting something considered

> old news

No one was scolded just informed that a lot more is known about the product

than the old forward looking statement indicated.

regards,

BobK

[Guest guest]

At 07:49 AM 01/16/2004, thecelestialspirit wrote:

>that's not the way I remember it, Bob.

Somehow that isn't suprising!

>Anyway, who says to discuss something you have to post evidence and

>research studies? Ever hear of a philosophical discussion, Bob?

Sure I have heard of philosophical discussions. Philosophical discussion

of HCV, in my estimation, would not help you, I or anyone else deal with HCV.

>No problem, I share my IDEAS on other groups.......Anyway, at least I HAVE

>my OWN thoughts/ideas, and don't have to base every one of them on what

>someone else has " proved " by some study!......

I have read some of your ideas, presented on other groups, that pertain to

HCV. The problem with your ideas is that many of the concepts you are

putting forth are so ill conceived and rife with msiconceptions, stemming

from a basic lack of knowledge of HCV virus and virus in general, that all

they do is cloud the issue with misinformation. To me HCV is not something

to be philosophical about. Facts about virus and especially the hepatitis

C virus are much more pertinent than someones irrelavent musings about

such. Misconceptions and misinformation do not help anyone in dealing with

HCV or any other disease. What they do is prevent forward progress by

clinging to arcane ideas which are based, not in facts, but in

opinion. Case in point your recent diatribe on jovo (HCV is not a virus

ect) was quite humorous and further demonstrates large holes in your

understanding on what a virus is and how they work let alone the different

types of virus.

Perhaps when I get back from fishing I canhelp you overcome these

misconceptions....not with philosophical discussions about virus but with

facts and those pesky dry studies you find so tedious to read.

regards,

BobK

[Guest guest]

that's not the way I remember it, Bob. Anyway, who says to discuss something you have to post evidence and research studies? Ever hear of a philosophical discussion, Bob? I have lots of IDEAS I'd like to discuss, and there aren't necessarily any studies needed to do that. People can present ideas and/or opinions as well as facts. This can stimulate the intellect just the same as reading some dry study. ......don't worry, I wouldn't try to do that here, since you and andy would never "allow" it. No problem, I share my IDEAS on other groups.......Anyway, at least I HAVE my OWN thoughts/ideas, and don't have to base every one of them on what someone else has "proved" by some study!...... blessings! Satya

Re: [ ] Infection with hepatitis C virus genotype 4 in the United States

At 10:54 AM 01/15/2004, thecelestialspirit wrote:>some may also be resistant to posting articles because if some here don't >agree with each word, you will be challenged endlessly and your post >picked apart to shreds.Satya you seem to be unable to grasp the concept of a discussion group is to discuss. What better to discuss than the articles posted?> That can make it unpleasant to post.Your too personally attached to your posts.> noticed a couple people who hardly ever post, did so last week, and were > shot down immediately. One was scolded for posting something considered > old newsNo one was scolded just informed that a lot more is known about the product than the old forward looking statement indicated.regards,BobK

[Guest guest]

that's your opinion, Bob, and you're certainly entitled to it! Have a good time fishing. No thanks on helping with my misconceptions when you get back. I already have a date. blessings! Satya

Re: [ ] Infection with hepatitis C virus genotype 4 in the United States

At 07:49 AM 01/16/2004, thecelestialspirit wrote:>that's not the way I remember it, Bob.Somehow that isn't suprising!>Anyway, who says to discuss something you have to post evidence and >research studies? Ever hear of a philosophical discussion, Bob?Sure I have heard of philosophical discussions. Philosophical discussion of HCV, in my estimation, would not help you, I or anyone else deal with HCV.>No problem, I share my IDEAS on other groups.......Anyway, at least I HAVE >my OWN thoughts/ideas, and don't have to base every one of them on what >someone else has "proved" by some study!......I have read some of your ideas, presented on other groups, that pertain to HCV. The problem with your ideas is that many of the concepts you are putting forth are so ill conceived and rife with msiconceptions, stemming from a basic lack of knowledge of HCV virus and virus in general, that all they do is cloud the issue with misinformation. To me HCV is not something to be philosophical about. Facts about virus and especially the hepatitis C virus are much more pertinent than someones irrelavent musings about such. Misconceptions and misinformation do not help anyone in dealing with HCV or any other disease. What they do is prevent forward progress by clinging to arcane ideas which are based, not in facts, but in opinion. Case in point your recent diatribe on jovo (HCV is not a virus ect) was quite humorous and further demonstrates large holes in your understanding on what a virus is and how they work let alone the different types of virus.Perhaps when I get back from fishing I canhelp you overcome these misconceptions....not with philosophical discussions about virus but with facts and those pesky dry studies you find so tedious to read.regards,BobK