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Sylvia,

After reading your mention of immune related illnesses in the

dedication, I didn't read the first part but jumped ahead to your

autoimmune and immune system section because the subject

interests me as I've reversed autoimmune disorders in the past.

Without thinking about it you made a good point for undenatured

whey on page 70. It is designed to be easily assimilated by the

highly permeable intestinal mucosa of baby mammals because they

do not have a well-enough developed intestinal wall or immune

system to tolerate adult foods. Whey is awesome for the immune

system.

I think you could have made it more clear that 70% of the immune

system is in the tissues immediately adjacent to the digestive

tract, rather than saying 70% of the immune system is " in the

digestive tract " .

On page 75 you mention you have lactose intolerance; it can be

eliminated by culturing a better bowel ecology with inulin and

other prebiotics, according to this British Medical Journal

study http://pmj.bmjjournals.com/cgi/content/full/80/946/447

which also points out that " probiotics have been shown clearly to

boost immunity in the elderly. "

Lots of similar work, some of it on my website, refutes the

concept of keeping microflora in the intestine to a minimum, a

concept championed by Elaine Gottchall and Michio Kushi, both of

whom you mention. These works are now long in the tooth even

though Kusi's book was revised in 1994, and we are leagues ahead

of where we were 12 years ago in terms of understanding how bowel

bacteria and prebiotics work. An important part of what we know

is that the probiotic bacteria mut be active, not simply added as

an already worked-out culture, to outcompete on the bowel lining;

competition requires active fermentation of prebiotics, which is

against the advice of both works.

Also, on page 78, although you did specify acidophilus I think

you meant to include other acid-producing lactobacilli in your

definition of probiotic. But lactobacilli are already naturally

higher numerically in the elderly gut, and get this -- so are

pathogenic organisms, so obviously lactobacilli are not stellar

performers as probiotics compared to bifidobacteria, small

fluctuations of which result in large numeric changes to

pathogens as well as lactobacilli. See Tungland's

Comprehensive Scientific Review on my website for more aong those

lines, including references.

Further, you recommend on page 78 against milk proteins, based on

your personal experience and your exposure to the NotMilk agenda,

even quoting some of it elsewhere; I'd suggest that you should

revise the language a bit for your second edition and perhaps

note for your readers that milk proteins are an issue only to a

fairly small minority. For the record, NotMilk prints what

satisfies their platform; note if you go there www.notmilk.com

you'll see that the articles are liberally sprinkled with

innuendo and speculation, arguably a hallmark of the agenda sites

but not of objective health reporting. A good rule of thumb is to

beware the taint of the agenda sites generally if you use them at

all, and be careful if you don't want to be tarred by the same

brush when you do quote such a site.

Moving on, according to this study in Blood Journal, platelet-

derived microparticles generated during thrombus formation

associate with local fibrin (the coagulating protein):

http://www.bloodjournal.org/cgi/content/abstract/87/11/4651

With this in mind, the platelet activation and clotting you

describe on page 75, is aggravated by the presence of higher than

normal amounts of the clotting protein fibrin in the elderly

because production of plasmin, the body's only natural enzyme to

break it down, falls off with age. The result is reduced

circulation and spontaneous clotting as blood coagulates more

easily.

This suggests increasing the dissolution of the fibrin to

youthful values will support biological function, and it does;

Taking fibrinolytic enzymes reduces clotting risk including heart

attack and stroke, without warfarin, and also reduces the clot-

forming effect of platelet activation by mast cells, i.e. with

little free fibrin to bind to you won't get the degree of

clotting that we would call excessive.

Blockbuster All Clear is an enzyme blend chosen by many

professionals: http://www.goodhealth.nu/us/1400 because it

contains nattokinase, serapeptase and Seaprose-S, all good

fibrinolytics with slightly different properties of dissolving

excess clotting. It also contains protease and lipase to help

scar tissue, fibrosis, adhesion and plaque dissolution.

On page 81 you state that the immune system must top the

replication rate of the infecting virus. Actually, because the

white blood cells operate many times before they die, they don't

actually have to match in numbers, and maintaining their

robustness and activity are much more important.

This is an important point I was going to get into on the candida

list anyway; nothing beats systemic candida like a robust and

aggressive immune response, and nothing makes the immune response

more robust and aggresive than using undenatured whey with

Transfer Factor Plus Advanced Formula.

Imagine having more than four times the immune response afforded

by natural killer cells, PLUS direct conferred immunity to a wide

range of specific organisms, PLUS natural immunomodulators in

both products to control an autoimmune or hyperensitive immune

condition, PLUS all the glutathione the white blood cells need to

work, and they need lots.

On page 83, your comment " high cholesterol or peri-vascular

disease can be caused by intestinal mucosal erosion " indicates an

acceptance of one or more of the cholesterol myths. High

cholesterol is not a disease and there has been no evidence to

show it causes disease, although if one is under oxidative stress

low-density cholesterol can certainly oxidize if it's present,

which is why we take antioxidants like vitamin E and C, and the

trace metal selenium. For more information, see the well

referenced and aptly titled " The Cholesterol Myths " by the

world's foremost cholesterol researcher, Uffe Ravnskov:

http://www.ravnskov.nu/cholesterol.htm

I don't want to make the posts very long so I'll sign off for

now. We can dicuss a few points out of the first half your ebook

later if you like, but frankly, given the errors and omissions on

the 20 pages or so I have commented on so far, I think you should

have made clear at the outset that it is an opinion piece, and

represent it only as what you prefer for yourself.

Duncan Crow

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