Guest guest Posted May 23, 2010 Report Share Posted May 23, 2010 One week is not very long.Is your Hashimoto's being treated sufficiently with replacement hormone. Fatigue, pain, depression, and constipation are all symptoms of hypothyroidism. Were these symptoms not as noticeable before you began LDN? If LDN is going to help your Hashi's it may take longer than you expect and probably a higher dose. But don't go too fast titering your dose. That could be too much shock to your system.Have you had very recent thyroid/adrenal labs? Do you plan to? Might be a good idea.The liquid will last for sure 30 days if prepped with distilled water and refrigerated.JackieFrom: maryellenmu@... <maryellenmu@...>Subject: [low dose naltrexone] 1 week on ldnlow dose naltrexone Date: Sunday, May 23, 2010, 9:53 AMI am on 1.5 ml of the mixed liquid and am having a lot of problems with depression/' I have hashimoto, fibro, chronic fatigue, pain, constipation, adrenal problems. Taking meds for thyroid and adrenal. The depression just seems to be getting worse. Has anyone experienced this.I don't care if i eat or get out of the bed.Also how long is the liquid ldn in the refigerator.Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2010 Report Share Posted May 23, 2010 On Sun, 23 May 2010 10:53:26 -0400, maryellenmu@... <maryellenmu@...> wrote:> I am on 1.5 ml of the mixed liquid and am having a lot of problems with > depression/' I have hashimoto, fibro, chronic fatigue, pain, > constipation, adrenal problems. Taking meds for thyroid and adrenal. > The depression just seems to be getting worse. Has anyone experienced > this.I don't care if i eat or get out of the bed.>> Also how long is the liquid ldn in the refigerator.>> ThanksAre you taking it at night?When I started LDN (for Crohn's, RA, asthma), and when my husband did too (post-polio syndrome), we both felt very edgy at first if we were awake when it started kicking in (the opioid blockade went into effect). Neither of us had/has the complication of adrenal problems or hishimoto's. But if you're not taking it at night, I would recommend doing so.n ______________________________A funny, touching gift book for cat lovers. Signed copies, free shipping (U.S., reduced elsewhere): Confessions of a Cataholic: My Life With the 10 Cats Who Caused My Addiction by n Van Til www.wordpowerpublishing.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 24, 2010 Report Share Posted May 24, 2010 If the liquid is in a Brown glass ,it is good up to a month. Depression is very much related to thyroid.are you being treated good with dessicated hormones or only levo. If you do not have high blood pressure you can try 3x500 on empty stomach of D-Phenylalnine.it will help with the fibro pains. http://www.iherb.com/ProductDetails.aspx?pid=8607 if you decide to buy at iherb.com you get 5 dollars off on your First order with this code ZAH179 Watch these films about fibro and maybe you can learn something there.he says that people with fibro have also serotone shortage.5-http is the answer there http://www.youtube.com/watch?v=vPGdqpMxU24 & translated=1 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2010 Report Share Posted May 26, 2010 > The liquid will last for sure 30 days if prepped with distilled water and refrigerated. > Jackie Research has shown that the liquid LDN will last at least 90 days in the refrigerator and at least 30 days unrefrigerated. We keep ours beside the bed to remember to take it as we are falling asleep. Francie http://www.LDN-for-MS.com My Story Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2010 Report Share Posted May 26, 2010 I think the 90 day date refers to pharmacy compounded LDN liquid.JackieFrom: FrancieS <francie@...>Subject: [low dose naltrexone] Re: 1 week on ldnlow dose naltrexone Date: Wednesday, May 26, 2010, 11:06 AM> The liquid will last for sure 30 days if prepped with distilled water and refrigerated.> JackieResearch has shown that the liquid LDN will last at least 90 days in the refrigerator and at least 30 days unrefrigerated. We keep ours beside the bed to remember to take it as we are falling asleep.Franciehttp://www.LDN-for-MS.com My Story------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2010 Report Share Posted May 27, 2010 Thanks for this info, Francie. It's important for people to know realistic parameters to work with. -- At 11:06 AM 5/26/2010, you wrote: > > The liquid will last for sure 30 days if prepped with distilled water > and refrigerated. > > Jackie > >Research has shown that the liquid LDN will last at least 90 days in the >refrigerator and at least 30 days unrefrigerated. We keep ours beside the >bed to remember to take it as we are falling asleep. > >Francie >http://www.LDN-for-MS.com My Story ~~~ There is no way to peace; peace is the way ~~~~ --A.J. Muste Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2010 Report Share Posted May 27, 2010 I repeat, it is my understanding that the 90 day limit is for pharmacy compounded LDN liquid. Anyone who has used liquid for pets from Skip's Pharmacy may be aware it comes with a 30 day expiration. Has Francie determined if that liquid with a 90 limit has not had preservatives added?For homemade liquid I would rather be safe and go with a thirty day limit. How many here use a new sterile syringe for each dosing?Jackie> > The liquid will last for sure 30 days if prepped with distilled water > and refrigerated.> > Jackie>>Research has shown that the liquid LDN will last at least 90 days in the >refrigerator and at least 30 days unrefrigerated. We keep ours beside the >bed to remember to take it as we are falling asleep.>>Francie>http://www.LDN-for-MS.com My Story~~~ There is no way to peace; peace is the way ~~~~ --A.J. Muste------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2010 Report Share Posted May 27, 2010 I would like to know more about Francie's experiences and knowledge base. I would be horrified to hear that anyone was using a brand new syringe every time they dosed with LDN. What a huge creation of waste. -- At 05:18 AM 5/27/2010, you wrote: >I repeat, it is my understanding that the 90 day limit is for pharmacy >compounded LDN liquid. Anyone who has used liquid for pets from Skip's >Pharmacy may be aware it comes with a 30 day expiration. Has Francie >determined if that liquid with a 90 limit has not had preservatives added? > >For homemade liquid I would rather be safe and go with a thirty day >limit. How many here use a new sterile syringe for each dosing? > >Jackie > > > > > > The liquid will last for sure 30 days if prepped with distilled water > > and refrigerated. > > > Jackie > > > >Research has shown that the liquid LDN will last at least 90 days in the > >refrigerator and at least 30 days unrefrigerated. We keep ours beside the > >bed to remember to take it as we are falling asleep. > > > >Francie > ><http://www.LDN-for-MS.com>http://www.LDN-for-MS.com My Story > > >~~~ There is no way to peace; peace is the way ~~~~ > --A.J. Muste > > > >------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2010 Report Share Posted May 27, 2010 When dissolved in distilled water, does the LDN stay in suspension? Does it dissolve? You can always wash out a syringe. You don’t have to put it into your mouth, you can drop it on a spoon. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2010 Report Share Posted May 28, 2010 The liquid LDN that we make from pills bought from Mexico lasts at least 30 days unrefrigerated. Research has shown that it lasts at least 90 days refrigerated. I hope this helps, Francie > I think the 90 day date refers to pharmacy compounded LDN liquid. > Jackie > > > > The liquid will last for sure 30 days if prepped with distilled water and refrigerated. > > Jackie > > Research has shown that the liquid LDN will last at least 90 days in the refrigerator and at least 30 days unrefrigerated. We keep ours beside the bed to remember to take it as we are falling asleep. > > Francie > http://www.LDN-for-MS.com My Story Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2010 Report Share Posted May 28, 2010 > I would like to know more about Francie's experiences and knowledge base. > > I would be horrified to hear that anyone was using a brand new syringe every time they dosed with LDN. What a huge creation of waste. > > -- I really don't have any medical background, although I do have degrees in genetics, with minors in anatomy and physiology. We manage a large ranch, which had up until recently 130+ horses, 50+ dogs, a small herd of llamas, and one cat. I take LDN for my MS and feel that I am in total remission after 10 years of a downhill battle with conventional therapies and drugs totaling nearly $3,000 per month. That goodness, I lost my insurance so that I could find LDN. You can find our background here: <http://www.Kristull.com> I am not sure where the somebody got the idea to use a new syringe every night. I do try to remember to trade it out every month or so. I do agree that it would be a horrible waste, but since it is not important to stay sterile, it just has not been necessary. It is not being injected with the syringe, just drunk. We have had no problem with this. I did get out a new syringe when I had to dose a horse and used the one from bedside :-) I try to impart only my own personal experience, or those that seem to be generally accepted, or that have actually been tested, with results published. From July 1, 2009 on this newsgroup: Here is what Larry Frieders the pharmacist had to say: STABILITY OF NALTREXONE From: " Larry J. Frieders " <larry@t...> Date: Wed Mar 3, 2004 5:44 pmSubject: NOT 1 day... NOT 1 week...BUT a MONTH or MORE! Naltrexone is quite stable in water. I am quoting from Trissel's book, " Stability of Compounded Formulations " , Second Edition, page 266 " Stability- indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively. " This is a reference book that every compounder OUGHT to have on hand. 4 degrees C is refrigeration and 25 degrees C is room temperature. We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it " stopped working " . Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 > I know that there are general rules. For instance, when Frontline for Dogs first came out, it was required to have a 2 year exp date, since they had not yet proved that it lasted longer than that. Once they had samples over two years old with no deterioration, they were allowed to remove the exp date. I think it is probably a good idea for Skip to put a 30 day exp date on liquid LDN, since we never know how it is actually being treated once dispensed, and nobody has proven scientifically that it is still good. I know that we have had no problem with using LDN made from dissolved from 50mg pills and kept at room temperature next to the bed. But since a pill only lasts about 18 days, we have not tested past 30 days ourselves. I hope this is more clear. Francie http://LDN-for-MS.com My Story ******************** > At 05:18 AM 5/27/2010, you wrote: > >I repeat, it is my understanding that the 90 day limit is for pharmacy > >compounded LDN liquid. Anyone who has used liquid for pets from Skip's > >Pharmacy may be aware it comes with a 30 day expiration. Has Francie > >determined if that liquid with a 90 limit has not had preservatives added? > > > >For homemade liquid I would rather be safe and go with a thirty day > >limit. How many here use a new sterile syringe for each dosing? > > > >Jackie Quote Link to comment Share on other sites More sharing options...
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