Re: Endorphins only at night?

[Guest guest]

How does LDN work?

http://www.low dose naltrexone.org/#How_does_LDN_work_

>

> Can someone please point me to some science behind the Bihari statement that:

" endorphins are made only between two and four in the

> morning " . I can't find any reference to nighttime endorphin production.

>

> Endorphins are also obviously produced during the day when it comes to sex,

" Runners High " , pain, spicy foods, etc.

>

[Guest guest]

Someone stated here that one can get 70% endorphin boost at night and 30% endorphin boost during the day. I'm still on the 9AM dosing. Where this is in print, I don't know.

[low dose naltrexone] Endorphins only at night?

Can someone please point me to some science behind the Bihari statement that: "endorphins are made only between two and four in themorning". I can't find any reference to nighttime endorphin production. Endorphins are also obviously produced during the day when it comes to sex, "Runners High", pain, spicy foods, etc.

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[Guest guest]

I recently had a Drs appointmnet and I asked if I should take it during the day or something to that effect and he was very adamant(sp?) that it should only be taken at night. I trust him very much and he has been very supportive with letters for my employer.

FYI

PS I had been taking it for months during the day because I had trouble sleeping at night. But with new meds and CPAP, I am sleeping more solidly now and much longer!! Feeling better.

Posted by: "JOYCE MARTINO" jam2006@... jam2006@...

Fri Feb 12, 2010 9:20 am (PST)

Someone stated here that one can get 70% endorphin boost at night and 30% endorphin boost during the day. I'm still on the 9AM dosing. Where this is in print, I don't know. [low dose naltrexone] Endorphins only at night?Can someone please point me to some science behind the Bihari statement that: "endorphins are made only between two and four in themorning". I can't find any reference to nighttime endorphin production. Endorphins are also obviously produced during the day when it comes to sex, "Runners High",

pain, spicy foods, etc.

[Guest guest]

Dr Zagon, in an interview with Boyle Bradley, confessed to being the source

of the misinformation about the " necessity " of night dosage. He has retracted

that, based on the extensive animal studies at Penn State, and says a person can

take it anytime. He recommends day time dosing to anyone who has experienced

lingering side effects from the night time dosing.

Anyone who may want to chase this down, go to Bradley's blog talk radio web

site and listen to the interview with Dr. Zagon. You will hear it from him

there, with all of the detail of his explanation.

Best, Mike

>

> I recently had a Drs appointmnet and I asked if I should take it during the

day or something to that effect and he was very adamant(sp?) that it should only

be taken at night. I trust him very much and he has been very supportive with

letters for my employer.

>  

> FYI

> PS I had been taking it for months during the day because I had trouble

sleeping at night. But with new meds and CPAP, I am sleeping more solidly now

and much longer!! Feeling better.

>  

>  

> Posted by: " JOYCE MARTINO " jam2006@...   jam2006@...

> Fri Feb 12, 2010 9:20 am (PST)

>

>

> Someone stated here that one can get 70% endorphin boost at night and 30%

endorphin boost during the day. I'm still on the 9AM dosing. Where this is in

print, I don't know.

>

> [low dose naltrexone] Endorphins only at night?

>

> Can someone please point me to some science behind the Bihari statement that:

" endorphins are made only between two and four in the

> morning " . I can't find any reference to nighttime endorphin production.

>

> Endorphins are also obviously produced during the day when it comes to sex,

" Runners High " , pain, spicy foods, etc.

>

[Guest guest]

dr zagon cannot change the fact that endorphines are produced between 2-4 am.dr zagon have little experience with treating people.the doctors with more experience with people like dr bihari,dr berkson and dr mccandless recomend to take it after 22.00.

dr skip is of the same mind.

dr mccandless developed specially the transdermal cream for the autists children so the parents can smear it after 22.00 without waking the children.

[Guest guest]

Quote:

" The brief blockade of opioid receptors between 2 a.m. and 4 a.m. that is caused

by taking LDN at bedtime each night is BELIEVED to produce a prolonged

up-regulation of vital elements of the immune system by causing an increase in

endorphin and enkephalin production. [Emphasis added.] "

It's a theory, an educated guess as to why LDN works. We can't say for certain

that it's a fact until enough scientific research has been conducted. It's

entirely possible that Dr. Bihari's theory will eventually be disproven.

Fortunately for us, LDN still works even if we don't know for sure why it works.

> >

> > Can someone please point me to some science behind the Bihari statement

that: " endorphins are made only between two and four in the

> > morning " . I can't find any reference to nighttime endorphin production.

> >

> > Endorphins are also obviously produced during the day when it comes to sex,

" Runners High " , pain, spicy foods, etc.

> >

[Guest guest]

What dosage and frequency should my physician prescribe?

http://www.low dose naltrexone.org/#What_dosage_and_frequency

LDN Taken of a Morning vs Night

http://ldn.proboards.com/index.cgi?board=forum & action=display & thread=1219

Why I do Bihari dosing protocol over Zagon/Gilhool

http://ldn.proboards.com/index.cgi?board=links & action=display & thread=1470

LDN-day/night dosing controversy/research

http://ldn.proboards.com/index.cgi?board=forum & action=display & thread=1541

Mechanisms involved in beneficial effect of LDN

http://ldn.proboards.com/index.cgi?board=forum & action=display & thread=1297

Speaking for myself, I have experimented with morning dosing, skipping doses,

increasing and reducing doses and find taking 4.5mgs LDN every night at 10pm to

be right for me and my multiple sclerosis. I have been a member of this group

for almost five years and have been using LDN since March 2005 and most LDN

users I know follow almost the same protocol and successfully. 3-4.mgs every

night between the hours of 9pm and 3am.

Art

>

> Can someone please point me to some science behind the Bihari statement that:

" endorphins are made only between two and four in the

> morning " . I can't find any reference to nighttime endorphin production.

>

> Endorphins are also obviously produced during the day when it comes to sex,

" Runners High " , pain, spicy foods, etc.

>

[Guest guest]

Dr. Tom Gilhooly says that taking LDN at night is not necessary, and he

recommends taking it during the day to minimize the impact on sleep.

See:

http://glasgowldn2009.com/2009/02/ldn-dose-timing/

Be sure to also read the comments on that page.

>

> dr zagon cannot change the fact that endorphines are produced between 2-4

am.dr zagon have little experience with treating people.the doctors with more

experience with people like dr bihari,dr berkson and dr mccandless recomend to

take it after 22.00.

> dr skip is of the same mind.

> dr mccandless developed specially the transdermal cream for the autists

children so the parents can smear it after 22.00 without waking the children.

>

[Guest guest]

every one must choose his doctor.i think that dr berkson and mccandless are the good once.everyone is free to choose.ifit is impossible to take at night then better in the day then nothing.it is second best and many were telling their experience about it.