Guest guest Posted March 3, 2001 Report Share Posted March 3, 2001 Anyone have medical abstracts that state that the Western Blot can revert to negative with abx treatment? I have a guy that emailed me that is in a pickle, his wife tested + and ins sent her to a specialist ( ahhuhh ) who said that her WB was neg, so she is now neg and Ins wants abx stopped. TYIA, Pepi Metzler ChocolatesFine Artisan candies, handmade with the finest ingredients. ___~----..,,. // ( )___ ) \.\ // // // \\ // // \\ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2009 Report Share Posted May 2, 2009 Can someone tell me the difference between Igm and Igg on a Western Blot test from Igenex?  I tested positive on the Igm for both igenex and CDC criteria but only tested positive on the Igg igenex criteria...not the igg CDC criteria.  Just wondering what this means... Owner Metro Dogs LLC [ ] Announcement: Under Our Skin (Please share with all you know) Dear Friends, As you may know, it has been quite a busy and eventful year for UNDER OUR SKIN, with accolades from audiences and press worldwide. We've received four " Best Documentary " awards, an " Audience Favorite " award, and top honors from medical and film organizations. We've also been successful in getting the film screened at no charge in over 500 communities nationwide. And with national spots on network TV and radio, our film has brought unprecedented attention to the issue of Lyme disease. But we have more work to do. We are now gearing up for the next phase--the Uncover the Epidemic national outreach campaign, which we're launching in conjunction with our theatrical and educational DVD release this summer. In addition to getting the film before mainstream audiences, we'll be partnering with national organizations interested in issues such as environmental awareness, affordable healthcare and insurance reform. We will also be working to get the film into classrooms, medical schools and libraries, so that the truth about Lyme disease (and the system that has kept it hidden) can no longer be ignored. Unfortunately, we don't have Hollywood studios backing our efforts, so we are financing this work ourselves. Revenue from DVDs sold to date is all going back into outreach and distribution. But it is not enough. We need to raise $100,000 in the next two and half months to continue our vital outreach work, including our awareness tour, advertising, PR and promotional materials. Never before has the Lyme community had a media tool like UNDER OUR SKIN. It is imperative we don't pass up this opportunity to create lasting mainstream awareness and change. As we are a 501©(3) nonprofit, your contributions are fully tax-deductible--and appreciated no matter what you can afford. Donors who contribute $250 or more will receive a signed movie poster and DVD when the " fully loaded " version is available later this summer. Donors who give $1000 or more (by June 1st) will receive these gifts plus recognition in the upcoming DVD discussion booklet. • Make a donation online using the widget bel ow, or go directly to the _UOS " donate " page_ (http://cts.vresp.com/c/?OpenEyePictures/f28692d196/3678ac5816/46c97bd906) . • Copy the widget below and embed it in your own blogs and web pages to help spread the word. • Send a check payable to Open Eye Pictures/UOS and mail to the address below. Thank you so much for your belief in our project and your continued support. Please check out www.underourskin.com to see the impact the film is already having, and how we're poised for more. Best Wishes, Andy Abrahams Producer/Director _UNDER OUR SKIN_ (http://cts.vresp.com/c/?OpenEyePictures/f28692d196/3678ac5816/6dd608d72b) Open Eye Pictures 2656 Bridgeway, Ste 202 Sausalito, CA 94965 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 4, 2009 Report Share Posted May 4, 2009 IgM is a sign of a current infection. IgG is a sign of a past exposure to or past infection by the organism michele, i copied this from a website for you.. Begley - Temporary Placement Manager From: <michelledianecox@...> Subject: Re: [ ] Igg and Igm Date: Saturday, May 2, 2009, 7:11 PM Can someone tell me the difference between Igm and Igg on a Western Blot test from Igenex?  I tested positive on the Igm for both igenex and CDC criteria but only tested positive on the Igg igenex criteria...not the igg CDC criteria.  Just wondering what this means... Owner Metro Dogs LLC Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 5, 2009 Report Share Posted May 5, 2009 That is good to know...because on my Lyme western blot test I had a lot of igg and igm bands that showed up and was curious what the difference was. Â Thanks! Owner Metro Dogs LLC P/973.417.1380 F/201.435.1487 www.metrodogs.biz Re: [ ] Igg and Igm Date: Saturday, May 2, 2009, 7:11 PM Can someone tell me the difference between Igm and Igg on a Western Blot test from Igenex? Â I tested positive on the Igm for both igenex and CDC criteria but only tested positive on the Igg igenex criteria...not the igg CDC criteria. Â Just wondering what this means... Owner Metro Dogs LLC Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 5, 2009 Report Share Posted May 5, 2009 I believe that this is, in essence, true. But I wonder... if it's that cut and dry why we don't have a test that can tell us if we WERE infected versus if we ARE infected. I never have been able to comprehend (maybe it's Lyme-brain?) why it's so bloody hard to be able to test for current infection in a treated Lyme patient. I'd have so many medical issues clearer if I just had that answer! I'd always understood that one denotes acute infection, the other long term infection...? (OR) > > From: <michelledianecox@...> > Subject: Re: [ ] Igg and Igm > > Date: Saturday, May 2, 2009, 7:11 PM > > > > Can someone tell me the difference between Igm and Igg on a Western Blot test from Igenex? Â I tested positive on the Igm for both igenex and CDC criteria but only tested positive on the Igg igenex criteria...not the igg CDC criteria. Â Just wondering what this means... > > > Owner > Metro Dogs LLC > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 There are exceptions to every rule. " IgM antibodies, when present in high numbers, represent a new active infection or an existing infection that has become reactivated. " " To recap, depending on the numbers, IgM is a sign of a current infection. IgG is a sign of a current infection, or of a past exposure to or past infection by the organism. " http://www.anapsid.org/lyme/wb.html " Serological testing for Lyme disease usually consists of testing for the IgM antibody which peaks between three to six weeks after the infection, and may persist throughout the course of the disease and may remain elevated for years after clinical remission. The IgG antibody will rise after the initial IgM peak. " http://74.125.93.132/search?q=cache:PRWvsuaEBQIJ:www.cambridgebiomedical.com/pdf\ s/TB050%2520Burgdorferi%2520IgG%2520IgM%2520Antibodies%252008-05-07.pdf+Igm+%26+\ Igg+%26+lyme & cd=29 & hl=en & ct=clnk & gl=us It can get very confusing. Having IgM antibodies does not necessarily mean a current infection. Likewise IgG can also mean a current infection. It is not black and white. I have had Lyme disease for 35 years and still have positive IgM antibodies. I have now chronic arthritic Lyme disease due to being undiagnosed for so many years. Every joint in my body in affected. V > > > > From: <michelledianecox@...> > > Subject: Re: [ ] Igg and Igm > > > > Date: Saturday, May 2, 2009, 7:11 PM > > > > Can someone tell me the difference between Igm and Igg on a Western Blot test from Igenex? Â I tested positive on the Igm for both igenex and CDC criteria but only tested positive on the Igg igenex criteria...not the igg CDC criteria. Â Just wondering what this means... > > > > > > Owner > > Metro Dogs LLC > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 One word greed. There is a band that is 100% indicator of Lyme. But due to the IDSA members having rights in proposed vaccinations that target this band they have gotten it removed as an indicator. Its sickening. > [ ] Re: Igg and Igm > > I believe that this is, in essence, true. But I wonder... if > it's that cut and dry why we don't have a test that can tell > us if we WERE infected versus if we ARE infected. > > I never have been able to comprehend (maybe it's Lyme-brain?) > why it's so bloody hard to be able to test for current > infection in a treated Lyme patient. I'd have so many medical > issues clearer if I just had that answer! > > I'd always understood that one denotes acute infection, the > other long term infection...? > > (OR) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 I just wanted to post few things about IGg's and IGm's that I learned. First for the " normal " understanding of these: Igm antibody's are short-term and appear within a few weeks after being exposed to some antigen (bacteria, protein, etc) After this, the Iggs appear. They have a much longer half-life in the body and the body will keep producing them which is how you build immunity. The body usually does not continue to generate Igm's after the initial infection. Even while you are still infected. As I said above, this is the " normal " way the body works. There seems to be evidence that in long term lyme infections the Igg bands will disappear completely over time (years), and Igm's will sometimes be present. The Igenics lab site has some information on this. http://www.igenex.com/lymeset2.htm If you google lyme igm, you can find other references. dave Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 Which band is the 100% indicator of Lyme? Sent from my iPhone On 6-May-09, at 10:27 AM, " " <msadams@...> wrote: > > > One word greed. > > There is a band that is 100% indicator of Lyme. But due to the IDSA > members > having rights in proposed vaccinations that target this band they have > gotten it removed as an indicator. Its sickening. > > > [ ] Re: Igg and Igm > > > > I believe that this is, in essence, true. But I wonder... if > > it's that cut and dry why we don't have a test that can tell > > us if we WERE infected versus if we ARE infected. > > > > I never have been able to comprehend (maybe it's Lyme-brain?) > > why it's so bloody hard to be able to test for current > > infection in a treated Lyme patient. I'd have so many medical > > issues clearer if I just had that answer! > > > > I'd always understood that one denotes acute infection, the > > other long term infection...? > > > > (OR) > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 7, 2009 Report Share Posted May 7, 2009 Can you please tell me what band is the 100% indicator of Lyme? Owner RE: [ ] Igg and Igm One word greed. There is a band that is 100% indicator of Lyme. But due to the IDSA members having rights in proposed vaccinations that target this band they have gotten it removed as an indicator. Its sickening. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 8, 2009 Report Share Posted May 8, 2009 From http://www.mdjunction.com/forums/lyme-disease-support-forums/general-support /154688-any1-have-1-band-pos-wb-then-igenix-more-band- See the bold section below.. ==================================================================== Here is the website for Igenex to help understand what the western blot means: http://www.igenex.com/lymeopt2.htm As has been mentioned, 41+ is non-specific for lyme but only testing positive for that band on most lyme tests does not rule anything in or out. The following are the bands are described by Igenex as somewhat-specific Lyme antibodies of importance in the IgG test: 23-25 kDa (Osp C); 31 kDa (Osp A); 34 kDa (Osp ; 39 kDa; 41 kDa; and 83-93 kDa7. ( " kDa " is used for molecular weight designations and " Osp " refers to outer surface protein of the bacteria.) For the IgM test, the CDC criteria for a positive result are two of the following three bands: 23-25 kDa (Osp C); 39 kDa; and/or 41 kDa.8,9 IGeneX adds the 31 kDa (Osp A), and/or the 34 kDa (Osp which were removed when there was an effort to create a vaccine for Lyme as these were the proteins that were used to try to create the vaccine. Looking at a test of mine from last year, Igenex reported on the following bands: 18, 22, 23-25, 28, 30, 31, 34, 39, 41, 45, 58, 66, 73, 83 - 93. When you receive the results, the " important " bands are double starred (I've seen a lot of these things!) which are the ones I mentioned above. It's always important to remember, though, that lyme should be a clinical diagnosis, not just the result of a seropositive test. Hope this isn't too much information at once. ====================================================== More on testing... http://www.ilads.org/files/burrascano_0905.pdf http://www.geocities.com/HotSprings/Oasis/6455/western-blot.txt > RE: [ ] Igg and Igm > > One word greed. > > > > There is a band that is 100% indicator of Lyme. But due to > the IDSA members > > having rights in proposed vaccinations that target this band > they have > > gotten it removed as an indicator. Its sickening. > > > > ------------------------------------ > > For free up to date information about Lyme disease and the known > co-infections delivered to your email address see: > Robynns_Lyme_List/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 10, 2009 Report Share Posted May 10, 2009 Thank you! Â That was very very helpful =) Owner Metro Dogs LLC RE: [ ] Igg and Igm From http://www.mdjunction.com/forums/lyme-disease-support-forums/general-support /154688-any1-have-1-band-pos-wb-then-igenix-more-band- See the bold section below.. Quote Link to comment Share on other sites More sharing options...
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