Guest guest Posted October 28, 2002 Report Share Posted October 28, 2002 Welcome, Joan! Sorry you've experienced nausea and headaches after taking methotrexate. Those are two well-known side-effects of the drug. http://www.rxlist.com/cgi/generic/mtx_ad.htm I hope changing to the injectable form helps. How long have you been administering it that way? Although I don't know how much you are taking right now, you may ask your physician if you can increase your folic acid to help. Yes, MTX does have a very good track record in the treatment of RA. Good luck! [ ] Methotrexate side effects > Hello, > > Ive had RA for 30years on and off, and obviously tried many drugs. At the moment I have been prescribed Methotrexate, and have been trying it since July. However I experienced some nausea and quite bad headaches for a couple of days after taking it. My specialist suggested trying it by injections and this I am doing at the moment. The dose has been reduced to only 5mg to see if it makes a difference, but I would be interested to know if anyone else has had the same problem. I also take Diclofenac and Folic Acid. I read that Methotrexate on the whole is a good treatment for RA and wonder if the side efffects are related to Mtx or maybe some other cause unrelated. Any help would be much appreciated. > > Joan. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2002 Report Share Posted October 28, 2002 Hi Joan B. I was on oral mtx and it gave me terrible stomach aches and diarrhea. When I took it through injections, I had no side effects at all except for fatigue the day after. Not only are the side effects less by injection, the meds are more effective. a > Hello, > > Ive had RA for 30years on and off, and obviously tried many drugs. At the > moment I have been prescribed Methotrexate, and have been trying it since > July. However I experienced some nausea and quite bad headaches for a couple > of days after taking it. My specialist suggested trying it by injections and > this I am doing at the moment. The dose has been reduced to only 5mg to see > if it makes a difference, but I would be interested to know if anyone else has > had the same problem. I also take Diclofenac and Folic Acid. I read that > Methotrexate on the whole is a good treatment for RA and wonder if the side > efffects are related to Mtx or maybe some other cause unrelated. Any help > would be much appreciated. > > Joan. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2002 Report Share Posted October 29, 2002 Joan: I too, take mtx orally. It always has left me nauseous, headachy and diarrhea. I recently was off it for three weeks due to being on antiobiotics and I could sure notice the difference. I hope you will do better as time goes on. Jan in SC Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2002 Report Share Posted October 29, 2002 Hi a, Thanks for reply. Youve probably heard the saying a little knowledge is a dangerous thing, Im finding the reverse is true. The internet is undoudtedly a wonderful tool, but some of the information you discover about the medication you take is quite scary. I have gone along for many years not really concerned about side effects until one day I typed in Search Methotrexate just for curiosity. Well you can imagine the reams of info that came back. So much so that I actually postponed going on it for a year. (a bad flare-up changed my mind) However Im still struggling to ignore all the bad news it seemed to bring. How do you cope with it all. Joan From: a Sent: Tuesday, October 29, 2002 3:16 AM Subject: Re: [ ] Methotrexate side effects Hi Joan B. I was on oral mtx and it gave me terrible stomach aches and diarrhea. When I took it through injections, I had no side effects at all except for fatigue the day after. Not only are the side effects less by injection, the meds are more effective. a > Hello, > > Ive had RA for 30years on and off, and obviously tried many drugs. At the > moment I have been prescribed Methotrexate, and have been trying it since > July. However I experienced some nausea and quite bad headaches for a couple > of days after taking it. My specialist suggested trying it by injections and > this I am doing at the moment. The dose has been reduced to only 5mg to see > if it makes a difference, but I would be interested to know if anyone else has > had the same problem. I also take Diclofenac and Folic Acid. I read that > Methotrexate on the whole is a good treatment for RA and wonder if the side > efffects are related to Mtx or maybe some other cause unrelated. Any help > would be much appreciated. > > Joan. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 4, 2002 Report Share Posted November 4, 2002 Joan, There are some days I want to bury my head in the sand and not know or care what any of these drug do to me as long as I get relief. The internet has made me afraid to take certain meds, but it has also made me feel better about taking certain meds. We have to keep in mind that the long list of potential side effects are just that  potential side effects. It doesn't mean it will happen. Most serious side effects are very rare, but must be listed so that we know what to watch for. There are many more people that have had good things to say about mtx. Now that you¹re aware of the potential side effects, you¹ll know to see your doctor if anything isn¹t quite right. a > Hi a, > Thanks for reply. Youve probably heard the saying a little knowledge is a > dangerous thing, Im finding the reverse is true. The internet is undoudtedly > a wonderful tool, but some of the information you discover about the > medication you take is quite scary. I > have gone along for many years not really concerned about side effects until > one day I typed in Search Methotrexate just for curiosity. Well you can > imagine the reams of info that came back. So much so that I actually postponed > going on it for a year. (a bad flare-up changed my mind) However Im still > struggling to ignore all the bad news it seemed to bring. How do you cope > with it all. > Joan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2006 Report Share Posted September 12, 2006 hi must be quick bc hard to sit long. have had a series of bad infections,, liver and pancreatic activity since i used mtx in l994. has anyone else had similar prblems? i'm very, very weak, too. drs are mystified. chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2006 Report Share Posted September 15, 2006 Wow I have no experience to share with you (and hopefully wont, sorry!) I've been off and on Methotrexate for a while, its done a decent job so far. I just wanted to write to say Im so sorry you are going through so much. Youre in my thoughts and prayers. --- podunkescape <podunkescape@...> wrote: > hi > must be quick bc hard to sit long. have had a > series of bad > infections,, liver and pancreatic activity since i > used mtx in l994. > has anyone else had similar prblems? i'm very, very > weak, too. drs are > mystified. chris > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2008 Report Share Posted March 23, 2008 Lynn, I have gotten cold sores my whole life, usually only once or twice a year. I started methotrexate about 6 months ago and ever since them have had 3 of them. They never occur inside my mouth, only around the lips and I even had one under my nose. I also noticed after starting the MTX it takes longer for them to heal. Just make sure you are taking your folic acid. That is supposed to help. Good luck! Quote Link to comment Share on other sites More sharing options...
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