Re: Medication Side-effects

[Guest guest]

Has anyone ever experienced severe side-effects from taking either a large dose

of Indocin (75mg+) or methotrexate? Thanks.

[Editor's Note: I'm curious as to why you would ask this question. Virtually

any medication, if taken in a large enough dose, can cause very severe side

effects. Indocin and MTX are powerful drugs in their own right even when taken

at normally prescribed doses. No medication should EVER be taken above the

prescribed dose without first consulting with your doctor. Damage from an

overdose could be irreparable and even deadly. Kathy F.]

[Guest guest]

I recently discovered that Indocin can really affect your blood pressure. I

had been taking 75mg timed release capsules twice a day for years. I was

also having a hard time controlling my blood pressure. At my last

Rheumatologist appt., my Dr. had me cut back to once a day. That was

frightening to have to cut back, but I seem to be doing ok. Becky

[ ] Re: Medication Side-effects

Has anyone ever experienced severe side-effects from taking either a large

dose of Indocin (75mg+) or methotrexate? Thanks.

[Editor's Note: I'm curious as to why you would ask this question.

Virtually any medication, if taken in a large enough dose, can cause very

severe side effects. Indocin and MTX are powerful drugs in their own right

even when taken at normally prescribed doses. No medication should EVER be

taken above the prescribed dose without first consulting with your doctor.

Damage from an overdose could be irreparable and even deadly. Kathy F.]

[Guest guest]

Leonora: I second Kathy's Editor's Note. However, if you're still

curious: 200 mg. of Indocin in 24 hours is as high as you ever want

to go, and the effects of overdose center around the stomach (nausea,

vomiting, etc.) and head (intense headaches). Not pretty.

As for methotrexate: you want to stay under 25 mg. a week (generally

considered the max oral dose); and as for " side effects " , severe is

the word: those who experience the severe side effects of MTX are no

longer around to detail the " experiences " .

D.

> Has anyone ever experienced severe side-effects from taking either

a large dose of Indocin (75mg+) or methotrexate? Thanks.

>

>

>

> [Editor's Note: I'm curious as to why you would ask this

question. Virtually any medication, if taken in a large enough dose,

can cause very severe side effects. Indocin and MTX are powerful

drugs in their own right even when taken at normally prescribed

doses. No medication should EVER be taken above the prescribed dose

without first consulting with your doctor. Damage from an overdose

could be irreparable and even deadly. Kathy F.]