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http://www.ncbi.nlm.nih.gov/pubmed/8289586

http://www.psychosomaticmedicine.org/cgi/reprint/51/4/441.pdf

Glucose (fasting and area under the curve) was not modified significantly after naltrexone administration. Baseline hormone levels were similar in the two groups, and they did not change after long-term treatment with naltrexone or placebo. In conclusion, these results support the hypothesis of elevated opioid tonus and increased insulin secretion as a possible mechanism of hyperinsulinism in a group of hyperandrogenic women of ovarian origin. This alteration could act as an additional factor in the pathogenesis of insulin resistance found in an important proportion of these patients. see -

http://cat.inist.fr/?aModele=afficheN & cpsidt=2445124

Celia, Scotland.celia@...

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could someone explain what this is saying in plain english please?

http://www.ncbi.nlm.nih.gov/pubmed/8289586

http://www.psychosomaticmedicine.org/cgi/reprint/51/4/441.pdf

Glucose (fasting and area under the curve) was not modified

significantly after naltrexone administration. Baseline hormone levels

were similar in the two groups, and they did not change after long-term

treatment with naltrexone or placebo. In conclusion, these results

support the hypothesis of elevated opioid tonus and increased insulin

secretion as a possible mechanism of hyperinsulinism in a group of

hyperandrogenic women of ovarian origin. This alteration could act as

an additional factor in the pathogenesis of insulin resistance found in

an important proportion of these patients. see -

http://cat.inist.fr/?aModele=afficheN & cpsidt=2445124

thanks

monique

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