LEF Colorectal cancer adjuvant protocol

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Health Concern

Colorectal cancer

Identifying and eradicating the causative factors responsible for the

development of colorectal cancer is of the utmost importance to those

individuals who are at high-risk for developing the disease and to those

who have been diagnosed with colorectal cancer. These factors include

diet, lifestyle, exercise, tobacco and alcohol use, parity, hormone use,

energy intake, and nonsteroidal anti-inflammatory drug (NSAID) use.

The following is a summary of what an individual with colorectal cancer

(either colon cancer or rectal cancer) should consider and discuss with

their physician, as an adjuvant approach to conventional colorectal

cancer therapy:

Cimetidine, 800 mg each night for 12 continuous months.

Curcumin, 10,800 mg, in divided doses of four 900-mg capsules 3 times a

day.

Lightly caffeinated green tea extract, 5,250 mg in divided doses of five

350-mg capsules 3 times daily with meals. If caffeine interferes with

sleep, take decaffeinated capsules in the evening. Each capsule should

contain at least 100 mg of epigallocatechin gallate (EGCG).

Se-methylselenocysteine, 200-400 mcg daily in divided doses.

Fish oil, 8 capsules of a supplement called Mega EPA supply 3200 mg of

EPA and 2400 mg of DHA.

Vitamin E succinate, 800-1200 IU daily.

Gamma E Tocopherol/Tocotrienols, 200 mg daily.

Vitamin D3, 4000-6000 IU, taken daily on an empty stomach with monthly

blood testing to monitor for toxicity. Reduce dosage at 6 months.

Water-soluble vitamin A, 100,000-300,000 IU daily, with monthly blood

testing to monitor for toxicity. Reduce dosage at 6 months (refer to

Appendix A: Vitamin A Precautions).

Modified citrus pectin, 15 grams daily in 3 divided doses.

Whey protein concentrate isolate, 10-20 grams three times daily.

Resveratrol, 20 mg daily.

Vitamin C, 4000-12,000 mg in divided doses throughout the day.

CoQ10, 100-300 mg daily.

Life Extension Mix, 3 tablets 3 times daily. (Patients with advanced

colon cancer may want to avoid Life Extension Mix and other

multivitamins since they all contain folic acid. While folic acid may be

the most effective nutrient to prevent colon cancer, in advanced stages,

or in combination with certain chemotherapy drugs, folic acid may be

detrimental because it may facilitate hypermethylation in colon cancer

cells.)

http://www.lef.org/protocols/prtcl-148.shtml