DMSO

[Guest guest]

DMSO carries stuff with it into the bloodstream that has a smaller molecular

weight than it does. It's a pretty small molecule, smaller than many bacteria.

I use a rule of thumb not to put anything with it I wouldn't put in my mouth.

If you're concerned, find the molecular weight of the substance you're

considering for transport. You can find an MSDS on most stuff (tho' not

necessarily your brand or that of the product you're using) with an internet

search.

saralou

apply only to Laboratories products

DMSO has the empirical formula C2H6OS, and a molecular weight of 78.13.

Molecular weight: 78.13, C 30.74%, H 7.74%, O 20.48%, S 41.43%, melting point

18.45°C (supercools easily), and a boiling point of 189°C. CAS# 67-68-5 "

http://www.jacoblab.com/dmso_protocols.htm

http://www.bulkmsm.com/research/msm/page12.htm

http://www.priondata.org/data/A_DMSO.html DMSO has the ability to pass

through every tissue and Cell Membrane of the body except the Enamel of Teeth,

fingernails and Hair without destroying the integrity of these tissues and Cell

Membranes (i.e. it is a membrane penetrate). DMSO also permits the passage of a

number of compounds across the barriers of Cell Membranes.

a.. readily absorbed when administered topically onto human Skin - peak levels

occur after 4-8 hours. Topical administered DMSO is slightly less bioavailable

than orally ingested DMSO.

b.. Orally ingested DMSO is also rapidly absorbed and reaches a blood serum

peak in 4 hours and becomes undetectable after 120 hours.

c.. readily crosses the Blood-Brain Barrier (this property of DMSO allows its

utilization as an effective vehicle for transporting other substances that may

not normally cross the Blood-Brain Barrier). e.g. Transport Into Brain of

Buthionine Sulfoximine, an inhibitor of Glutathione Synthesis, is Facilitated By

Esterification & Administration of Dimethyl Sulfoxide. Steinherz R, Martensson

J, Wellner D, Meister A: Brain Research. 518:115-9, 1990. (Abstract 2390716).

Caution: many of the industrial grade DMSO solutions intended for use as

solvents have an acid or Acetone contamination of several percent. Acetone

contamination can lead to serious medical consequences - because of its small

molecular weight, Acetone is readily carried into the blood by

Acetone-contaminated DMSO.

Full chemistry review: http://www.dmso.org/articles/information/szmant.html

The DMSO molecule is ten-sided with a center occupied by a Sulfur atom. It

contains two methyl groups - an oxygen atom and a nonbinding electron pair -

located at the points of the tetrahydron.

Molecular weight: 78.15

Freezing point: 68 degrees Fahrenheit

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Re: [ ] Overnight Cure?

I don't know much one can aceept as valid the following from the BC Cancer

Agency (Whatever that is) or someone selling DMSO. However, at least we will

know more about it. Joe C.

History of DMSO

" A by-product of paper manufacturing, it was first synthesized in 1866. As

medication, DMSO was used initially in the 1960's. Following FDA [Food and

Drug Administration] approval for experimental use, it was applied in

topical form to relieve pain, reduce swelling, heal injuries such as muscle

strains and sprains, and treat arthritis. " (Cassileth)

DMSO was first reported in 1963 by Stanley , M.D. of the University of

Oregon Medical School. claimed that " DMSO could penetrate skin and

produce local analgesia, decrease pain, and promote healing of injured

tissue. " (Hafner)

" Today, DMSO is approved only to treat interstitial cystitis (a bladder

disorder) and as veterinary therapy to reduce swelling in horses and dogs.

It is under study for conditions including arthritis, sprains, and a skin

disorder known as scleroderma. DMSO is also used to deliver drugs through

the skin and to preserve living cells when they are frozen. " (Cassileth)

DMSO can travel through the skin and into tissue - Dr. Stanley

suggested that it might become a vehicle for administering cancer drugs into

tumours. (CA)

" There is some evidence that DMSO can also protect against radiation

damage. " (Dunlop)

DMSO received publicity as a painkiller when a U.S. governor reported that

his wife, who was dying of bone cancer, had used veterinarian DMSO to

relieve her pain. (Dunlop)

Proponent / Advocate Claims

" DMSO stimulates various parts of the immune system and scavenges hydroxyl

radicals, the most potent of free radicals. Since free radicals promote

tumor growth, this may be one of the mechanisms by which DMSO interferes

with the development of cancer. It may also explain why patients who receive

DMSO while undergoing either chemotherapy or radiation (both which generate

free radicals in order to kill cancer cells) are far less prone to such side

effects as hair loss, nausea, and dry mouth. " (Diamond)

" Both DMSO and retinoic acid (RA) were found to be effective in reducing

cell growth. DMSO, however, was found to be the stronger inhibitor. " (Grunt)

" Dose-dependent protection against tumor development was afforded by

allopurinol and DMSO. " (Salim)

Supporters believe that DMSO can cut through a protein shell surrounding

cancer cells and so may assist medications and the immune system in

attacking cancer cells. (Ontario)

It is also believed that DMSO can decrease the energy level of cancer cells

and cause them to become benign. (Ontario)

The principal proponent is Mrs. Mildred , owner and administrator of

the Degenerative Disease Medical Center in Las Vegas. Mrs. is editor

of Preventive Health News, a monthly tabloid that promotes DMSO as a

treatment for arthritis, mental illness, emphysema and cancer.

In the past 2 years, the Centre claims to have " treated 30 patients with

advanced brain tumors using intravenous and oral laetrile, DMSO and

" metabolic therapy " , which consists of vitamins, enzymes and coffee

retention enemas. They claim that their study indicated that the 30 patients

are in various stages of regression. Six patients exhibited decrease in size

of the tumor to total remission. This was based on brain scan results. Two

have had partial regression based on independent brain scans and two have

had prolongation of life. " (CA)

Procaine hydrochloride, a local anesthetic, is also given intravenously to

cancer patients receiving treatment at The Center because it is believed

that it increases the speed with which their pain is relieved. (CA)

Life Extension Products advertises: " DMSO could be one of the most effective

anti-cancer agents known, it has the properties desired in any cancer drug

and has been used successfully with chemotherapy. " (Consumer Reports)

Professional Evaluation / Critique

" In study with rats, DMSO had no effect when used alone against prostate

cancer but, again, when combined with other therapeutic agents, the doses

could be lowered and the same effects achieved. " (Diamond)

" Some studies have shown that DMSO increases the metastatic [cancer

spreading] potential of tumor cells. " (Maehara)

" The only approved uses of DMSO in the United States are for treating

interstitial cystitis (a rare type of bladder inflammation) and as a

veterinary drug to reduce swelling due to trauma in horses and dogs. "

(Hafner)

An in vitro study (Bentel) showed invasiveness and metastatic potential

(potential for the cancer to invade and spread) were enhanced after culture

with DMSO.

Toxicity / Risks

" Industrial-grade DMSO should never be used because contaminants could

produce serious reactions. " (Hafner)

" Intravenous administration of DMSO may cause damage to liver, kidneys,

blood-forming organs and central nervous system. " (Ontario)

DMSO may cause headaches, dizziness, nausea, and sedation. (Ontario)

DMSO was found to cause damage to the gastric mucosa. (Sorbye)

Eye changes in experimental animals resulted in the discontinuation of the

use of DMSO for human illnesses in the 1960s. (CA)

" Dimethyl sulfoxide causes superficial mucosal damage to the gastric mucosa

and increased secretion of fluid into the stomach. " (Sorbye)

DMSO could prove fatal if used as a retention enema. As the Life Extension

ad stated, DMSO does " take other products with it " as it " passes through

body tissue. " In the rectum, these " other products " might include bacterial

toxins that DMSO could carry through the intestinal wall and into the

bloodstream.

" For a person who is already weakened by cancer, the effect of the absorbed

toxins could be life-threatening. " (Consumer Reports)

" Never mix DMSO with any chemical or drug and then apply it to the skin, as

the proper DMSO dosage for such a combination unknown and could be harmful,

cautions Dr. Callebout. " (Diamond)