Re: Endo worried about my liver

[Guest guest]

What are your live function values?

AST, ALT, Ferritin, Hepatitis

Here is a link that lists testosterone as bad for the liver:

http://www.fpnotebook.com/GI187.htm

http://www.pfizer.com/download/uspi_depo_testosterone.pdf

http://www.androgel.com/diagnosis/treating.htm

My opinion: if you have high liver function values, then you better get

checked. I am battling a similar problem. I am very concerned. I think you said

that you don't have hemochromatosis. If so, that's good.

In a message dated 3/29/2004 11:06:36 PM Eastern Standard Time,

nickso@... writes:

I have been happy with my Endo, but now she is saying that she is

worried about some of my high liver counts. I am on 5G Testim and

around the 500 T range (from 95), but I don't have the " good " feeling

as I did when I was on 10 G of Testim for about 2 weeks.

I want to try 10 G of Testim for about a month, see how I feel and

get my T levels on 10G.

She is not wanting me to go to 10G because she believes that TRT is

bad for the liver.

I personally feel that if I was on 10G, I would feel much better and

my stress levels would drop and this in turn would also help my liver.

Any input on the TRT and liver issues?

Thanks in advance,

Nickso

[Guest guest]

Intetresting thought process but I am not so sure. Did you have

your liver values checked prior to TRT? Specifically you need to

know your AST and ALT. Elevated levels on these could well be one

of the causes of your low testosterone.

Just out of habit, as I have had elevated liver values inthe past, I

take 1000 mg of milk thistle and a suppliment called Liv52 daily.

Since doing that my lever values have been normal. Small price to

pay.

y

> I have been happy with my Endo, but now she is saying that she is

> worried about some of my high liver counts. I am on 5G Testim and

> around the 500 T range (from 95), but I don't have the " good "

feeling

> as I did when I was on 10 G of Testim for about 2 weeks.

> I want to try 10 G of Testim for about a month, see how I feel and

> get my T levels on 10G.

>

> She is not wanting me to go to 10G because she believes that TRT

is

> bad for the liver.

> I personally feel that if I was on 10G, I would feel much better

and

> my stress levels would drop and this in turn would also help my

liver.

>

> Any input on the TRT and liver issues?

>

> Thanks in advance,

> Nickso

[Guest guest]

Here was most of my blood work.

Ferritin 290 12-282

SGOT(AST) 33 5-35

SGPT(ALT) 85 7-56

Iron 48 35-158

Hepatitis A Negative

Hepatitis B Core Negative

Hepatitis B Surf Negative

Hepatitis C Negative

Glucose 94 65-110

BUN 15 8-25

Creatinine 1.1 0.8-1.4

Calculated Bun/Creat 13.6 6-28

Sodium 139 133-146

Potassium 4.3 3.5-5.3

Chloride 103 97-110

Carbon Dioxide 27 18-30

Calcium 9.4 8.5-10.5

Protein, Total 7.5 6.0-8.4

Albumin 4.4 2.9-5.0

Calculated Globulin 3.1 2.0-3.8

Calculated A/G Ratio 1.42 0.9-2.5

Bilirubin, Total 1.8 0.1-1.3

Platelet Count 163 130-400

FSH 2.1 1.5-14

LH 2.4 1.0-9.0

Testosterone 172 241-827

TSH 1.1 0.3-5.1

> What are your live function values?

>

> AST, ALT, Ferritin, Hepatitis

>

> Here is a link that lists testosterone as bad for the liver:

> http://www.fpnotebook.com/GI187.htm

>

> http://www.pfizer.com/download/uspi_depo_testosterone.pdf

>

> http://www.androgel.com/diagnosis/treating.htm

>

> My opinion: if you have high liver function values, then you better

get

> checked. I am battling a similar problem. I am very concerned. I

think you said

> that you don't have hemochromatosis. If so, that's good.

>

>

>

>

>

> In a message dated 3/29/2004 11:06:36 PM Eastern Standard Time,

> nickso@c... writes:

> I have been happy with my Endo, but now she is saying that she is

> worried about some of my high liver counts. I am on 5G Testim and

> around the 500 T range (from 95), but I don't have the " good "

feeling

> as I did when I was on 10 G of Testim for about 2 weeks.

> I want to try 10 G of Testim for about a month, see how I feel and

> get my T levels on 10G.

>

> She is not wanting me to go to 10G because she believes that TRT is

> bad for the liver.

> I personally feel that if I was on 10G, I would feel much better

and

> my stress levels would drop and this in turn would also help my

liver.

>

> Any input on the TRT and liver issues?

>

> Thanks in advance,

> Nickso

>

>

>

[Guest guest]

I suffer from secondary hypo as a result of iron overload (hemochromatosis).

My ferritin was 812. I now give blood every week. After giving blood my body

uses a bit of the stored iron when creating replacement blood.

Looking at your labs I believe you need to consult with a gastroenterologist.

Even if he does nothing - you should consider giving blood every six weeks,

or however often the clinic will allow. Maybe you can even get the Dr. to put

you on bloodletting until your Ferritin is below 20. Then give blood every two

months to keep it low. Such action would take iron out of the equation. Also

you can go to www.kimballgenetics.com and take the hemochromatosis gene test.

My gene test came back negative. However, my Dad was just diagnosed with

hemochromatosis too. The gene test isn't perfect because it doesn't include all

known variants, but its better than nothing.

I only know about one type of iron overload - hemochromatosis. Your levels,

while not dramatic by any means are much higher than the ideal which is below

150 for a man. You need to get that checked out. Iron overload causes secondary

hypogonadism. BTW, don't worry that your serum iron is well within normal, it

is possible to have iron overload but normal serum iron.

Also noticed that your bilrubin is high.

Get checked for liver disease.

Make sure you don't take any vitamin C supplements, acetominiphin, cook with

or eat from cast iron, and shy from alcohol.

sources:

www.ironoverload.org

www.irondisorders.org

www.americanhs.org

Take this serious.

Have you ever used steroids?

Good luck,

In a message dated 3/30/2004 11:58:47 AM Eastern Standard Time,

nickso@... writes:

Here was most of my blood work.

Ferritin 290 12-282

SGOT(AST) 33 5-35

SGPT(ALT) 85 7-56

Iron 48 35-158

Hepatitis A Negative

Hepatitis B Core Negative

Hepatitis B Surf Negative

Hepatitis C Negative

Glucose 94 65-110

BUN 15 8-25

Creatinine 1.1 0.8-1.4

Calculated Bun/Creat 13.6 6-28

Sodium 139 133-146

Potassium 4.3 3.5-5.3

Chloride 103 97-110

Carbon Dioxide 27 18-30

Calcium 9.4 8.5-10.5

Protein, Total 7.5 6.0-8.4

Albumin 4.4 2.9-5.0

Calculated Globulin 3.1 2.0-3.8

Calculated A/G Ratio 1.42 0.9-2.5

Bilirubin, Total 1.8 0.1-1.3

Platelet Count 163 130-400

FSH 2.1 1.5-14

LH 2.4 1.0-9.0

Testosterone 172 241-827

TSH 1.1 0.3-5.1

[Guest guest]

Thanks for the info (this has opened my eyes and I have already left

a message for my doc)

I have never used steroids, but do like my beer.

I have always had stomach issues and also suffer from Irritable Bowel

Syndrome, all of these were listed in the links you sent. I do have

idiopathic secondary hypogonadism.

Yes, I also noticed my bilrubin was high and I have always had nice

dark skin, but don't spend much time in the sun.

I did have a liver sonogram and it came back normal.

I do take vitamin C supplements since it is " the thing to do "

I will keep pressing.

Anyone else have issues with high iron and low T?

Nickso

> I suffer from secondary hypo as a result of iron overload

(hemochromatosis).

> My ferritin was 812. I now give blood every week. After giving

blood my body

> uses a bit of the stored iron when creating replacement blood.

>

> Looking at your labs I believe you need to consult with a

gastroenterologist.

> Even if he does nothing - you should consider giving blood every

six weeks,

> or however often the clinic will allow. Maybe you can even get the

Dr. to put

> you on bloodletting until your Ferritin is below 20. Then give

blood every two

> months to keep it low. Such action would take iron out of the

equation. Also

> you can go to www.kimballgenetics.com and take the hemochromatosis

gene test.

> My gene test came back negative. However, my Dad was just diagnosed

with

> hemochromatosis too. The gene test isn't perfect because it doesn't

include all

> known variants, but its better than nothing.

>

> I only know about one type of iron overload - hemochromatosis. Your

levels,

> while not dramatic by any means are much higher than the ideal

which is below

> 150 for a man. You need to get that checked out. Iron overload

causes secondary

> hypogonadism. BTW, don't worry that your serum iron is well within

normal, it

> is possible to have iron overload but normal serum iron.

>

> Also noticed that your bilrubin is high.

>

> Get checked for liver disease.

>

> Make sure you don't take any vitamin C supplements, acetominiphin,

cook with

> or eat from cast iron, and shy from alcohol.

>

> sources:

>

> www.ironoverload.org

> www.irondisorders.org

> www.americanhs.org

>

> Take this serious.

>

> Have you ever used steroids?

>

> Good luck,

>

>

>

>

> In a message dated 3/30/2004 11:58:47 AM Eastern Standard Time,

> nickso@c... writes:

> Here was most of my blood work.

>

> Ferritin 290 12-282

> SGOT(AST) 33 5-35

> SGPT(ALT) 85 7-56

> Iron 48 35-158

>

> Hepatitis A Negative

> Hepatitis B Core Negative

> Hepatitis B Surf Negative

> Hepatitis C Negative

>

> Glucose 94 65-110

> BUN 15 8-25

> Creatinine 1.1 0.8-1.4

> Calculated Bun/Creat 13.6 6-28

> Sodium 139 133-146

> Potassium 4.3 3.5-5.3

> Chloride 103 97-110

> Carbon Dioxide 27 18-30

> Calcium 9.4 8.5-10.5

> Protein, Total 7.5 6.0-8.4

> Albumin 4.4 2.9-5.0

> Calculated Globulin 3.1 2.0-3.8

> Calculated A/G Ratio 1.42 0.9-2.5

> Bilirubin, Total 1.8 0.1-1.3

> Platelet Count 163 130-400

> FSH 2.1 1.5-14

> LH 2.4 1.0-9.0

> Testosterone 172 241-827

> TSH 1.1 0.3-5.1

>

>

>