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Re: Cordyceps???

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Never tried it, but I found this:

The History of Cordyceps

(This article courtesy of R-Garden Internationale)

Cordyceps is a fungus, like mushrooms, reishi, shitake, etc., but

belongs to

a different family, which represents only 2% of all the fungus grown

in the

world. A mature Cordyceps can measure from 2 to 5 inches in height

and up to

1 1/2 inches in diameter.

According to botanical classification, Cordyceps Sinensis can only

be found

in some isolated places in the southwestern part of China, such as

Quihai

and Tibet, 12,000 or more feet above sea level. The ecology of these

areas

is not found in any other part of the world. Due to the harsh

environment

and consequently very small production, wild Cordyceps is usually

very

expensive, selling for up to $1000 for 100 grams in Japan. And yet,

the

supply can hardly meet the demand.

The Medicine and Science Academy of China began an earnest research

effort

on Cordyceps more than 20 years ago by forming a team of 200 experts

from

various disciplines. After 10 years of intensive and exhaustive

studies, a

particular kind of Cordyceps from Quihai providence was selected for

pilot

production due to its resistance to disease, its fast growth,

nutritional

content, and easy adaptability to many growing media. A production

technology was developed and commercial production began a few years

ago.

Cordyceps was first mentioned as an anti-aging herb around 1700 BC

during

the Yin Dynasty. The first Emperor of the Chin Dynasty (259 BC -

210 BC) paid 1 ounce of gold for a few days' portion of Cordyceps.

Two

books written in the 15th and 18th centuries by Tibetan scholars

described

Cordyceps in great detail. In 1726, a French missionary sent some

Cordyceps

from China to Paris. A Mr. Reaumur introduced the product at a

scientific

gathering and wrote a paper the next year about Cordyceps, which

started the

research effort in Europe. In 1728, Cordyceps was first imported

into Japan.

In the classical Chinese medicinal texts such as New Herbs, Herbal

Pharmacology, and Herbal Classification, Cordyceps was described in

great

detail as a very effective herb for treating circulatory,

respiratory,

immune, sexual dysfunction, as well as a host of other health

problems. It

was also classified as a general health tonic because of its ability

to

improve energy, stamina, appetite and sleeping patterns.

In the early 1970's the Chinese government researchers began

collecting and

cultivating more than 200 species of wild Cordyceps Sinensis. After

extensive studies, one kind was selected for commercial production.

Extensive research and clinical studies have been carried out using

scientific procedures and standards that verify the product's safety

and

health benefits.

Laboratory Tests

The calmative effect of Cordyceps on the central nervous system is

quite

noticeable. When 5 grams per Kilogram of weight of Cordyceps is

injected

into the abdominal cavity of mice, obvious sedative results are

produced and

it prolongs the sleeping time of the mice. It can also reduce the

spasm of

the mice due to the toxic effect of nicotine and reduces the death

rate of

these mice. Cordyceps can increase the spleen weight of laboratory

mice

suffering from gamma ray radiation. It can also increase the total

DNA, RNA,

and protein content in the spleen of these mice. Cordyceps can

increase the

macrophage cell production, possibly due to the increase of DNA,

RNA, and

protein which increases the new cell growth in the mice's spleens.

Cordyceps can slow down the heart beat, increase the blood supply to

the

coronary arteries and also increase the total blood volume output of

the

heart of laboratory frogs. It can prolong the survival time of mice

under

hypo-oxygenated conditions. It also relaxes the blood vessel walls

so that

the blood flow to the heart is increased and the blood pressure is

lowered.

Cordyceps can relax the bronchial walls of laboratory mice as well

as having

sedative, antitussive, and anti-inflammatory properties, thus it can

be

effective against cough, phlegm, asthma, and other respiratory

ailments.

Cordyceps also increases the adrenaline production of laboratory

mice.

Cordyceps acts as a very potent male sex hormone. It increased the

testicle

weight of laboratory mice.

Cordyceps has the ability to increase the ATP production in the

mitochondria

of human cells and thus increases the energy level of the people

taking this

product. Three grams per kilogram of weight can increase the SOD

content in

mice's liver tissue, prevent or decrease the formation of Peroxide

lipids,

and prevent or decrease the formation of oxidise enzyme in the

brain. So its

anti-aging effects are obvious.

Several in vitro studies indicate that Cordyceps can control the

growth of

certain kinds of bacteria in the human body.

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> Does anyone have experience with Cordycep mushrooms? My doc told

me

> they increase sex drive, but he doesn't know which mechanism it

works

> on.

>

> If anyone has tried them, and found an increase in LH or T levels

or

> a decrease in E, please let me know.

>

> Thanks!!!

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Thanks tallen,

I did a search on this before and never found any studies relating it

to hormones, it would be interesting if someone came across such a

study...

Thanks!!!

> > Does anyone have experience with Cordycep mushrooms? My doc told

> me

> > they increase sex drive, but he doesn't know which mechanism it

> works

> > on.

> >

> > If anyone has tried them, and found an increase in LH or T levels

> or

> > a decrease in E, please let me know.

> >

> > Thanks!!!

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Guest guest

How about these?

Life Sci. 2004 Jul 16;75(9):1051-62. Related Articles, Links

In vivo stimulatory effect of Cordyceps sinensis mycelium and its

fractions on reproductive functions in male mouse.

Huang YL, Leu SF, Liu BC, Sheu CC, Huang BM.

Department of Cell Biology and Anatomy, College of Medicine,

National Cheng Kung University, #1, Ta-Hsueh Road, Tainan, Taiwan

70101, ROC.

Cordyceps sinensis (CS), an Ascomycetes fungus parasitic to

Lepidoptera larvae, has been traditionally used as nutritious food

for the enhancement on sexual performance and the restitution of

impairment in sexual function in Chinese society. We have previously

demonstrated the stimulatory effect of CS and its fractions on

steroidogenesis both on primary mouse Leydig cells and MA-10 mouse

Leydig tumor cells. In the present studies, we determined the in

vivo effects of CS and its fractions on steroidogenesis in mouse.

Different concentrations of CS and CS fractions (0.02 and 0.2 mg/g

body weight) were fed to immature or mature mice from 1 to 7 days.

The plasma levels of testosterone were evaluated by

radioimmunoassay. The weights of reproductive organs were also

determined. Results illustrated that CS significantly induced plasma

testosterone levels both in immature and mature mice in 3 and/or 7

days treatment (p < 0.05). F2 and F3 at 0.02 and/or 0.2 mg/g body

weight for different feeding duration could also significantly

stimulated plasma testosterone levels both in immature and mature

mice (p < 0.05). In general, CS, F2 and F3 didn't have considerable

effect on the weights of reproductive organs. Taken together, these

studies illustrate that CS and its fractions significantly

stimulated in vivo mouse testosterone production.

PMID: 15207653 [PubMed - in process]

: Life Sci. 2003 Sep 5;73(16):2127-36. Related Articles, Links

In vivo and in vitro stimulatory effects of Cordyceps sinensis on

testosterone production in mouse Leydig cells.

Hsu CC, Huang YL, Tsai SJ, Sheu CC, Huang BM.

Department of Cell Biology and Anatomy, College of Medicine,

National Cheng Kung University, 1 University Road, 701 Tainan,

Taiwan.

The in vivo and in vitro effects of Cordyceps sinensis (CS) and its

extracted fractions on the secretion of testosterone in mice were

studied. CS, F2 (water soluble protein), and F3 (poorly water

soluble polysaccharide and protein) significantly stimulated in

vitro testosterone production in purified mouse Leydig cells.

However, F1 (water soluble polysaccharide) had no effect (p>0.05).

F2 and F3 stimulated in vitro testosterone production in dose- and

time-dependent relationships with maximal responses at 3 mg/ml for 3

h (p<0.05). An in vivo study illustrated that testosterone levels in

plasma were significantly increased by CS, F2, and F3, respectively

(p<0.05). Because CS, F2, and F3 stimulated both in vitro and in

vivo testosterone secretions in mice, it is possible that CS might

contribute to an alternative medicine for the treatment of some

reproductive problems caused by insufficient testosterone levels in

human males.

PMID: 12899935 [PubMed - indexed for MEDLINE]

FEBS Lett. 2003 May 22;543(1-3):140-3. Related Articles, Links

Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig

cell steroidogenesis.

Hsu CC, Tsai SJ, Huang YL, Huang BM.

Department of Cell Biology and Anatomy, College of Medicine,

National Cheng Kung University, #1 Ta-Hsueh Road, 701, Tainan,

Taiwan.

We demonstrate the mechanism by which Cordyceps sinensis (CS)

mycelium regulates Leydig cell steroidogenesis. Mouse Leydig cells

were treated with forskolin, H89, phorbol 12-myristate 13-acetate,

staurosporine, or steroidogenic enzyme precursors with or without 3

mg/ml CS; then testosterone production was determined. H89, but not

phorbol 12-myristate 13-acetate or staurosporine, decreased CS-

treated Leydig cell steroidogenesis. CS inhibited Leydig cell

steroidogenesis by suppressing the activity of P450scc enzyme, but

not 3beta-hydroxysteroid dehydrogenase, 17alpha-hydroxylase, 20alpha-

hydroxylase, or 17beta-hydroxysteroid dehydrogenase enzymes. Thus,

CS activated the cAMP-protein kinase A signal pathway, but not

protein kinase C, and attenuated P45scc enzyme activity to reduce

human chorionic gonadotropin-stimulated steroidogenesis in purified

mouse Leydig cells.

PMID: 12753921 [PubMed - indexed for MEDLINE]

> > > Does anyone have experience with Cordycep mushrooms? My doc

told

> > me

> > > they increase sex drive, but he doesn't know which mechanism

it

> > works

> > > on.

> > >

> > > If anyone has tried them, and found an increase in LH or T

levels

> > or

> > > a decrease in E, please let me know.

> > >

> > > Thanks!!!

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Hi Tallen,

Thanks it looks like it does increase T levels as well!!!

> > > > Does anyone have experience with Cordycep mushrooms? My doc

> told

> > > me

> > > > they increase sex drive, but he doesn't know which mechanism

> it

> > > works

> > > > on.

> > > >

> > > > If anyone has tried them, and found an increase in LH or T

> levels

> > > or

> > > > a decrease in E, please let me know.

> > > >

> > > > Thanks!!!

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