Re: I have to vetch about some Dr's

[Guest guest]

I worked with Drs for many years, they HATE you knowing more about stuff

than them LOL, as is always going to be the case with our kids. The most

successful DAN Drs are those with Autism very close in the family.

Trouble is, here in the Uk there are so many disallusioned Drs's they don;t

seem to have umph required to spend 2 hours on the internet and see we aren;t

all talking out of our backsides!!

I am lucky to have a general pediatrician, who reminds be each visit I know

more than him, has both CSB and sbook and has promised to read them. He

will coz he knows I will test him! He took diligent notes about me seemingly

controlling Sam's seizures with B6 Mag and Taurine (he had to ask twice about

that one! AMINO ACID DR!!) and said he'd heard of Magnesium being used in

Neuro problems. Bless him, I'm sure he finds our consults more educational

than I do but he's clinical director for a large urban ped dept and one day,

one

thing will get through and they'll take more notice of him as the top

guy............in the meantime he's good for basic tests and stuff.

Took me 11 other arrogant etc Drs to find him

Mandi in UK

Not sure what is so much fun about sticking your frickin' head in the sand,

but apparently it's many doctors' first choices for pastimes....

Happy Holidays,

[Guest guest]

Medical Hypotheses

Volume 64, Issue 2 , 2005, Pages 312-315

Could one of the most widely prescribed antibiotics amoxicillin/clavulanate “

augmentin™†be a risk factor for autism?

Summary

Autism is an ever increasing problem in the United States. Characterized by

multiple deficits in the areas of communication, development, and behavior;

autistic children are found in every community in this country and abroad.

Recent

findings point to a significant increase in autism which can not be accounted

for by means such as misclassification. The state of California recently

reported a 273% increase in the number of cases between 1987 and 1998. Many

possible causes have been proposed which range from genetics to environment,

with a

combination of the two most likely. Since the introduction of

clavulanate/amoxicillin in the 1980s there has been the increase in numbers of

cases of

autism.

In this study 206 children under the age of three years with autism were

screened by means of a detailed case history. A significant commonality was

discerned and that being the level of chronic otitis media. These children were

found to have a mean number 9.96 bouts of otitis media (with a standard error of

the mean of ±1.83). This represents a sum total for all 206 children of 2052

bouts of otitis media. These children received a mean number of 12.04 courses of

antibiotics (standard error of the mean of ±.125). The sum total number of

courses of antibiotics given to all 206 children was 2480. Of those 893 courses

were Augmentin. with 362 of these Augmentin courses administered under the age

of one year.

A proposed mechanism whereby the production of clavulanate may yield high

levels of urea/ammonia in the child is presented. Further an examination of this

mechanism needs to be undertaken to determine if a subset of children are at

risk for neurotoxicity from the use of clavulanic acid in pharmaceutical

preparations.

Joan Fallon,

1234 Central Avenue, Suite 1B, Yonkers, NY 10704, USA

Received 23 June 2003;  accepted 12 June 2004.  Available online 17 November

2004.

[Guest guest]

By the same token there are children who have never been vaccinated who have

autism. Being closed minded to multiple etiologies is foolish. Vetching

about such a thing is only a disservice to the many children like mine who have

autism and not the usual circumstances, so open up your mind and read the entire

article.

Rich

[Guest guest]

Hello,

Antibiotics cause a lot of oxidative stress - which is seothing that researchers

are finding to be consistent in autism i.e. high level of lipid peroxidation.

I noticed in a psychophysiology text I was studying a few years ago that

anicimycin is given to rats to cause interference with a cognitive function -- I

believe memory, but I wil have to find that reference again. (That will take a

lot of reading to find that one little word - it isn't indexed. I just checked

for it now and did a brief scan -darn!). I am not sure that this is an

antibiotic, but by its name it looks like it could be one -- at least a compound

derived from a fungus or mold.Molds and fungi are powerful things. If you find

out anything further about this me know!

NM

phonesister@... wrote:

Medical Hypotheses

Volume 64, Issue 2 , 2005, Pages 312-315

Could one of the most widely prescribed antibiotics amoxicillin/clavulanate “

augmentin™†be a risk factor for autism?

Summary

Autism is an ever increasing problem in the United States. Characterized by

multiple deficits in the areas of communication, development, and behavior;

autistic children are found in every community in this country and abroad.

Recent

findings point to a significant increase in autism which can not be accounted

for by means such as misclassification. The state of California recently

reported a 273% increase in the number of cases between 1987 and 1998. Many

possible causes have been proposed which range from genetics to environment,

with a

combination of the two most likely. Since the introduction of

clavulanate/amoxicillin in the 1980s there has been the increase in numbers of

cases of

autism.

In this study 206 children under the age of three years with autism were

screened by means of a detailed case history. A significant commonality was

discerned and that being the level of chronic otitis media. These children were

found to have a mean number 9.96 bouts of otitis media (with a standard error of

the mean of ±1.83). This represents a sum total for all 206 children of 2052

bouts of otitis media. These children received a mean number of 12.04 courses of

antibiotics (standard error of the mean of ±.125). The sum total number of

courses of antibiotics given to all 206 children was 2480. Of those 893 courses

were Augmentin. with 362 of these Augmentin courses administered under the age

of one year.

A proposed mechanism whereby the production of clavulanate may yield high

levels of urea/ammonia in the child is presented. Further an examination of this

mechanism needs to be undertaken to determine if a subset of children are at

risk for neurotoxicity from the use of clavulanic acid in pharmaceutical

preparations.

Joan Fallon,

1234 Central Avenue, Suite 1B, Yonkers, NY 10704, USA

Received 23 June 2003; accepted 12 June 2004. Available online 17 November

2004.

[Guest guest]

Interesting, but my daughter never had an ear infection or any antibiotics

until she had her first ear infection at 7. She was already diagnosed with

autism by age 3.

Re: Re: I have to vetch about some Dr's

Medical Hypotheses

Volume 64, Issue 2 , 2005, Pages 312-315

Could one of the most widely prescribed antibiotics amoxicillin/clavulanate

“

augmentin™†be a risk factor for autism?

Summary

Autism is an ever increasing problem in the United States. Characterized by

multiple deficits in the areas of communication, development, and behavior;

autistic children are found in every community in this country and abroad.

Recent

findings point to a significant increase in autism which can not be

accounted

for by means such as misclassification. The state of California recently

reported a 273% increase in the number of cases between 1987 and 1998. Many

possible causes have been proposed which range from genetics to environment,

with a

combination of the two most likely. Since the introduction of

clavulanate/amoxicillin in the 1980s there has been the increase in numbers

of cases of

autism.

In this study 206 children under the age of three years with autism were

screened by means of a detailed case history. A significant commonality was

discerned and that being the level of chronic otitis media. These children

were

found to have a mean number 9.96 bouts of otitis media (with a standard

error of

the mean of ±1.83). This represents a sum total for all 206 children of 2052

bouts of otitis media. These children received a mean number of 12.04

courses of

antibiotics (standard error of the mean of ±.125). The sum total number of

courses of antibiotics given to all 206 children was 2480. Of those 893

courses

were Augmentin. with 362 of these Augmentin courses administered under the

age

of one year.

A proposed mechanism whereby the production of clavulanate may yield high

levels of urea/ammonia in the child is presented. Further an examination of

this

mechanism needs to be undertaken to determine if a subset of children are at

risk for neurotoxicity from the use of clavulanic acid in pharmaceutical

preparations.

Joan Fallon,

1234 Central Avenue, Suite 1B, Yonkers, NY 10704, USA

Received 23 June 2003; accepted 12 June 2004. Available online 17 November

2004.