Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Blood levels from my central line. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Laurie- THANK YOU SO MUCH! You have relieved my mind. I was told by Dr. H in NY that to have mito you had to have an elevated lactic acid level. Well I've never had mine to be elevated and Dr. Cohen has never made anything of it. I was really panicked after I've had this mito Dx for nearly 2 yrs for another specialist to tell me that. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Laurie- THANK YOU SO MUCH! You have relieved my mind. I was told by Dr. H in NY that to have mito you had to have an elevated lactic acid level. Well I've never had mine to be elevated and Dr. Cohen has never made anything of it. I was really panicked after I've had this mito Dx for nearly 2 yrs for another specialist to tell me that. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Was a little uncertain for a lil bit. I feel alot better now though. I have total trust in Dr. Cohen and his definitive Dx. My muscle biopsy showed the depletion of mitochondria. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Were these blood levels or CSF levels? LILQT4U1984@... wrote: >Was wondering about my lab results. > >My lactate was within normal range. Pyruvate was high. Lactate/Pyruvate >Ratio was low. What would that mean? > >I know you are generally looking for a high lactate. > >Thanks! > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Were these blood levels or CSF levels? LILQT4U1984@... wrote: >Was wondering about my lab results. > >My lactate was within normal range. Pyruvate was high. Lactate/Pyruvate >Ratio was low. What would that mean? > >I know you are generally looking for a high lactate. > >Thanks! > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 The ratio is felt to be the indicator that my docs look at, but I think it is a high ratio, not low (but not sure). My lactate is always in the normal range, although I have never had it drawn during a really bad crash. laurie > From: LILQT4U1984@... > Reply-To: > Date: Mon, 27 Dec 2004 14:56:31 EST > To: , mito > Subject: lactate/pyruvate > > Was wondering about my lab results. > > My lactate was within normal range. Pyruvate was high. Lactate/Pyruvate > Ratio was low. What would that mean? > > I know you are generally looking for a high lactate. > > Thanks! > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 The ratio is felt to be the indicator that my docs look at, but I think it is a high ratio, not low (but not sure). My lactate is always in the normal range, although I have never had it drawn during a really bad crash. laurie > From: LILQT4U1984@... > Reply-To: > Date: Mon, 27 Dec 2004 14:56:31 EST > To: , mito > Subject: lactate/pyruvate > > Was wondering about my lab results. > > My lactate was within normal range. Pyruvate was high. Lactate/Pyruvate > Ratio was low. What would that mean? > > I know you are generally looking for a high lactate. > > Thanks! > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 , You were afraid you didn't have Mito? Sygeek > Laurie- > > THANK YOU SO MUCH! You have relieved my mind. I was told by Dr. H in NY > that to have mito you had to have an elevated lactic acid level. Well I've > never had mine to be elevated and Dr. Cohen has never made anything of it. I > was really panicked after I've had this mito Dx for nearly 2 yrs for another > specialist to tell me that. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 , You were afraid you didn't have Mito? Sygeek > Laurie- > > THANK YOU SO MUCH! You have relieved my mind. I was told by Dr. H in NY > that to have mito you had to have an elevated lactic acid level. Well I've > never had mine to be elevated and Dr. Cohen has never made anything of it. I > was really panicked after I've had this mito Dx for nearly 2 yrs for another > specialist to tell me that. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 I have a specific deficiency in my muscle biopsy, complex II/III confirming mito and my lactate is normal. Pyruvate is high but I was told that a high pyruvate with a normal lactate is useless.. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Rest easy, an elevated lactic acid level is never elevated in some people. I would trust Dr. C. laurie > From: LILQT4U1984@... > Reply-To: > Date: Mon, 27 Dec 2004 15:36:30 EST > To: > Subject: Re: lactate/pyruvate > > Laurie- > > THANK YOU SO MUCH! You have relieved my mind. I was told by Dr. H in NY > that to have mito you had to have an elevated lactic acid level. Well I've > never had mine to be elevated and Dr. Cohen has never made anything of it. I > was really panicked after I've had this mito Dx for nearly 2 yrs for another > specialist to tell me that. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2004 Report Share Posted December 27, 2004 Hi , You are right, they do LOOK for a HIGH Lactate. But if your Lactate is LOW, that doesn't mean that you DON'T have MITO. Most times my Lactate is HIGH, Only once did it come back LOW. Although my Pyruvate is ALWAYS LOW.!! I honestly don't think they are looking at the lactate levels as closely or as much as they did years ago. Most doctors seem to not comment on the results unless it is totally out of the normal ranges. So rest assured, take a deep breath, you have your Mito dx with your muscle biopsy. Gee..that sounds like you should be happy that you have Mito, I didn't mean it to sound that way, you know what I mean. Hugs, Ann-Marie lactate/pyruvate Was wondering about my lab results. My lactate was within normal range. Pyruvate was high. Lactate/Pyruvate Ratio was low. What would that mean? I know you are generally looking for a high lactate. Thanks! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 28, 2004 Report Share Posted December 28, 2004 I had high blood lactate (from arm draw) once, out of about 7 tests. My pyruvate is always low, the ratio of lactate to pyruvate ranged from normal (10 - 20) up to 100 or more (indicative of mitochondrial problems). I have a " light case " of mitochondrial disease, symptom-wise, but interestingly, I've had a high lactate/pyruvate ratio (over 100 sometimes) and zero Complex I activity upon fresh muscle biopsy (I think normal for my age was 100 activity, and normal for older people was 50 activity - I had ZERO), as well as lactic acid buildup in the brain. I think it's difficult to get a good lactate/pyruvate blood test at " the local hospital " , as there are things like not putting on a tourniquet and adding the perchloric acid right away to the sample that most local places wouldn't know about. None of the local blood drawing stations would do it, and my local hospital redid my first set of tests four times before they got it right. Now I call them to make sure they have the materials and staff ready before I go in. I also have taken the prescription for the lab tests to the lab the day before, so they can figure out how many of what kind tubes etc. they need to use for each test. I haven't heard of high pyruvate in mitochondrial disease, but remember most of us have different " flavors " of mitochondrial disease, even if the same complex is affected, so don't let our experiences affect your discussions with your doctor. My doctor had a problem where the nurse had reviewed my results and said they were " okay " because the lactate was normal and the pyruvate was low - usually I guess " low " is considered " good " . When the doctor reviewed my results, she knew they supported the mito disorder diagnosis, and sent me for further tests. Take care, RH > I have a specific deficiency in my muscle biopsy, complex II/III confirming > mito and my lactate is normal. Pyruvate is high but I was told that a high > pyruvate with a normal lactate is useless.. > > > > Quote Link to comment Share on other sites More sharing options...
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