Re: CoQ10 and potential drug interactions

[Guest guest]

-Jean

I was given this booklet while having some pretesting done before

surgery at Mt.Auburn Hospital. I was distressed to see that

tricyclics were affected, because Austen takes nortriptyline!

You can definately post this info!!

Gwen

mom to Austen GA2 age 7

-- In Mito , Jean Shepherd wrote:

> Gwen;

>

> Who gave you this booklet? I am quite disturbed by the addition of

> Glyburide to the list of statin drugs. May I copy your post and

let the

> members of the AdultMito list have this information please?

>

> Jean

>

>

>

> Gwen Abele wrote:

>

> > I thought that some of you might be interested in possible drug

> > interactions with CoQ10...which I had never been told of. I was

given

> > a booklet previous to minor surgery I had the other day, warning

of

> > potential problems with combinations of foods, drugs and herbs.

> > Source is from RENAL NUTRITION FORUM, Summer 2001, Vol.20, No.3.

> >

> > CoQ10: immunostimulant/cardiovascular diseases/periodontal disease

> >

> > potential interactions: Statins (eg.lovastatin, cerivastain,

> > pravastatain, simvastatin, atoryvastatin, fluvastatin),

gemfibrozil,

> > tricyclic antidepressants, (e.g., amitriptvline, notriptyline,

> > despramine), glyburide.

> >

> > potential outcomes of interaction: Statins, gemfibrozil, tricyclic

> > antidepressants, and glyburide decreases endogenous levels of

CoQ10.

> >

> > Recommended actions: The significance of drug induced decreases in

> > endogenous CoQ10 levels is uncertain. Supplementation with CoQ10

or

> > increases in the current CoQ10 dosage are potential options to

offset

> > this effect. Monitor INR values and adjust warfarin dose as

necessary.

> >

> > Hope that this info is valuable.

> >

> > Gwen

> > mom to Austen GA2

> >

> >

> >

> > Please contact mito-owner with any problems or

questions.

> >

> >

> >