Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 -I believe that mitochondria are inherited only from the mother. http://www.mostgene.org/gd/gdvol10b.htm Mitochondria are passed from generation to generation only through maternal egg cells where they are abundant. Those present in sperm are concentrated in the tail and do not contribute to the compliment of the fertilized zygote. Molecular genetic tracking of polymorphic or variable regions through families and even across the millenia of human evolution confirm maternal inheritance of mitochondrial DNA. http://www.genetics.com.au/Genetics2004/FactSheets/8.asp CAN MUTATIONS IN THE MITOCHONDRIAL GENES BE INHERITED? The number of mitochondria in every cell of a person's body varies from a few to hundreds. All of these mitochondria, and therefore the DNA within the mitochondria, descend from the small number of mitochondria present in the original egg cell at the time of that person's conception. The sperm does not contribute any mitochondria to the baby. Thus an individual's mitochondria are only inherited from his or her mother. An abnormality in one of the mitochondrial genes can therefore be passed by the mother in her egg cells. As most of the mother's egg cells carry the same mitochondrial mutation, the risk of this mother having another affected child with the mitochondrial disorder is high. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 -I believe that mitochondria are inherited only from the mother. http://www.mostgene.org/gd/gdvol10b.htm Mitochondria are passed from generation to generation only through maternal egg cells where they are abundant. Those present in sperm are concentrated in the tail and do not contribute to the compliment of the fertilized zygote. Molecular genetic tracking of polymorphic or variable regions through families and even across the millenia of human evolution confirm maternal inheritance of mitochondrial DNA. http://www.genetics.com.au/Genetics2004/FactSheets/8.asp CAN MUTATIONS IN THE MITOCHONDRIAL GENES BE INHERITED? The number of mitochondria in every cell of a person's body varies from a few to hundreds. All of these mitochondria, and therefore the DNA within the mitochondria, descend from the small number of mitochondria present in the original egg cell at the time of that person's conception. The sperm does not contribute any mitochondria to the baby. Thus an individual's mitochondria are only inherited from his or her mother. An abnormality in one of the mitochondrial genes can therefore be passed by the mother in her egg cells. As most of the mother's egg cells carry the same mitochondrial mutation, the risk of this mother having another affected child with the mitochondrial disorder is high. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 -I believe that mitochondria are inherited only from the mother. http://www.mostgene.org/gd/gdvol10b.htm Mitochondria are passed from generation to generation only through maternal egg cells where they are abundant. Those present in sperm are concentrated in the tail and do not contribute to the compliment of the fertilized zygote. Molecular genetic tracking of polymorphic or variable regions through families and even across the millenia of human evolution confirm maternal inheritance of mitochondrial DNA. http://www.genetics.com.au/Genetics2004/FactSheets/8.asp CAN MUTATIONS IN THE MITOCHONDRIAL GENES BE INHERITED? The number of mitochondria in every cell of a person's body varies from a few to hundreds. All of these mitochondria, and therefore the DNA within the mitochondria, descend from the small number of mitochondria present in the original egg cell at the time of that person's conception. The sperm does not contribute any mitochondria to the baby. Thus an individual's mitochondria are only inherited from his or her mother. An abnormality in one of the mitochondrial genes can therefore be passed by the mother in her egg cells. As most of the mother's egg cells carry the same mitochondrial mutation, the risk of this mother having another affected child with the mitochondrial disorder is high. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 It would depend on if your problem is in your nuclear or your mitrochondira dna. My son's " defect " in nuculear from both his father and from me. His mito are not getting the correct instructions on how to process. My own and my husband's defects had to have come from one or the other of our parents as we both have one bad gene. I did hear of a mito passing down to a child this last year from the father which they had thought was impossible. Twana I was just > wondering how many here think they inherited mito from their father. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 It would depend on if your problem is in your nuclear or your mitrochondira dna. My son's " defect " in nuculear from both his father and from me. His mito are not getting the correct instructions on how to process. My own and my husband's defects had to have come from one or the other of our parents as we both have one bad gene. I did hear of a mito passing down to a child this last year from the father which they had thought was impossible. Twana I was just > wondering how many here think they inherited mito from their father. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 It would depend on if your problem is in your nuclear or your mitrochondira dna. My son's " defect " in nuculear from both his father and from me. His mito are not getting the correct instructions on how to process. My own and my husband's defects had to have come from one or the other of our parents as we both have one bad gene. I did hear of a mito passing down to a child this last year from the father which they had thought was impossible. Twana I was just > wondering how many here think they inherited mito from their father. Quote Link to comment Share on other sites More sharing options...
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