Re: MODY

[Guest guest]

Hi,

I have lived through what you have described, except no one knew about it

15-20 years ago. You are fortunate indeed to have a diagnosis and a treatment

plan. Hope that all works well and that those horrible lows.

Gail

[Guest guest]

GREETINGS --

The following might be old hat to you, but if not it might provide

some lead for your own research. The article comes from the Diabeto

Valens website and offers some additional insight regarding this rare

form of the disease.

wambo1941

PS As an aside here it sounds like you were experiencing a " honeymoon

period " soon after being diagnosed that was short lived.

Maturity Onset Diabetes Of the Young (MODY)

Introduction:

Often have we come across people, who have told us that they have

been diagnosed with diabetes either in their childhood or in their

adolescent years. We might sometimes shrug it off as an early

diagnosis or feel sorry for the person and just forget it. But this

kind of diabetes is widely prevalent and often goes unrecognized.

Scientifically termed as MODY (Maturity Onset Diabetes of the Young),

it affects 1-2% of people with diabetes.

There are three main factors associated with MODY:

Diabetes often develops before the age of 25.

Diabetes runs in families from one generation to the next.

Diabetes may be treated by diet or oral medications and does not

always need insulin treatment.

MODY runs in families:

Of the many causes for the onset of diabetes in people, family

history is one. MODY runs in families, due to the passing of a

defective gene from the parents to their offspring by a mode called

Autosomal Dominant Inheritance. In this method the defective gene

from any one of the parents can cause the disease to manifest this is

quite unlike the other method called Autosomal dominance in which two

genes, one from each of the parents is needed to manifest the

disease. All children of an affected parent with MODY have a 50%

chance of inheriting the affected gene and developing MODY

themselves. It is important that MODY be recognized as early as

possible because there are different types of MODY. By finding out

which type of MODY a person has, the most appropriate treatment for

them can be determined. As it runs in families, it is important to

realize that even other family members are at a risk of inheriting

it.

The different types of MODY

MODY is caused by change in a single gene. A lot of research has been

done in this regard and 5 genes have been identified and isolated,

which are believed to trigger the onset of MODY.

> Hey yall--

> I hope everyone is having a great last month of summer! I'm new to

> this group but so far it seems great and I'm glad to be part of it.

I

> live just outside Washington, DC, but I'm vacationing in Vermont

for

> the month of August. I was diagnosed with Type I diabetes 2 1/2

years

> ago and its been a series of ups and downs since then. After being

> first diagnosed, I was hospitalized, etc. However, my diabetes was

> not really progressing (which was great news!) and my A1C's were at

a

> non-diabetic level, so they thought I might have slowly progressing

> type I. However, I began to have a series of really bad,

unexplained

> lows which lasted a few weeks but eventually went away. More

recently

> I had another unexplained low and had to be hospitalized. I had

been

> sick much of this year and this just made things worse. About a

month

> later I had another series of lows. At this point I was really

> feeling miserable and so I went to the Joslin Diabetes Center in

> Boston. They began doing lots of tests, and eventually through a

> place in London, found out that I have MODY (mature onset diabetes

in

> the young). Not much is known about MODY as it is a rare form of

> diabetes which was frustrating. About a month afterwards I was

still

> feeling very sick, and was diagnosed with Fibromyalgia. This year

has

> been a real struggle for me in terms of my health, I ended up

missing

> about 40 days of school. Sorry to ramble on and on... I was

> wondering, does anyone else have MODY or know anything about it?

I'm

> still trying to learn about it and how to best manage it. I hope

> everyone else is doing well, sorry this post was so long!!

>

> Best,

>

> PrettyInPink1331@a...