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Re: Progesterone and Fibroid Growth Info

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Hi Ann

I found this very interesting. I was diagnosed with a small fibroid

about 1cm during a lap for endo and uterus repair, in June last

year. After my surgery, my gynie put me on 3 x 10mg

medroxyprogesterone a day to control the endo.

After one week, I noticed a pain in my lower right side, at that

time it was just a niggle and wasnt always there. Within a month it

had increased to very sharp intense pain, that stabbed about 3 times

a day. After the 6th week, I started a pain diary and realised that

the pain was coming within half an hour of taking my tablet. I went

to the gynie and told him what was happening and that I thought the

tablets were causing this pain. He laughed me off, saying it wasnt

possible.

After the second month, I couldnt take the pain anymore, it was 24

hours a day 7 days a week, and pushed my GP to give me an US. This

is when I was told that my fibroid was now 4.5cm x 2.5cm, and

pulling my repaired uterus over.

I went back and told the doc what was found, and still was told that

this wasnt the cause of my pain. I decided to stop taking the

tablets because I was convinced there was a link.

Within 3 weeks, the pain decreased by 25%. Now 8 weeks later, the

pain is niggling all the time, and only intense when I have done

alot of walking or standing for long periods.

I am a hundred percent sure that the medroxyprogesterone is the

culprit, and as I havent had another US done since the end of

October I am unsure how big the fibroid is now.

I might just pass the link onto my gynie and ask him to read it, as

I found it fascinating to say the least. Thanks for the info.

Suziedee

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Suzi,

Your doc may well dismiss the information, claiming that info from

the internet can't be trusted. I do believe that I've posed some

valid questions though regarding the possible influence of estrone

versus progesterone in the luteal phase contributing to fibroid

growth.

They haven't done enough research yet in my mind, not enough to be

conclusive or to take into account the different life stages we are

in and differences between our hormonal situations.

I had two women write back to me about this post (you are the 3rd) --

one told me that progesterone has helped her tremendously, another

told me of how using a phytoestrogen gel rapidly grew her fibroid. I

have yet to meet anyone whose fibroid grew using progesterone but

that doesn't mean it can't. [ladies please write back if you have had

growth that you believed is linked to progesterone]

Also, consider the fact the progesterone primes the estrogen

receptors -- that might be why RU-486 works. So, does RU-486 block

progesterone from doing what it does, or does it block progesterone

from helping estrogen do what it does. Chicken or egg -- they don't

know.

--Ann

> I might just pass the link onto my gynie and ask him to read it, as

> I found it fascinating to say the least. Thanks for the info.

>

> Suziedee

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Hi Ann..

I wrote to Eisinger (who conducted the Mifepristone study in Rochester)

about this His reply was theoretically Aygestin could cause fibroid growth, but

if it was helping to control bleeding I should stay on it. I have been on

continuous Aygestin for 3 months and today at a check-up my gyn said that my

uterus was a bit smaller 10 weeks vs 12 weeks 7 months ago. That doesn't mean

that the fibroids are smaller...but probably they haven't grown

diane

Re: Progesterone and Fibroid Growth Info

I had two women write back to me about this post (you are the 3rd) --

one told me that progesterone has helped her tremendously, another

told me of how using a phytoestrogen gel rapidly grew her fibroid. I

have yet to meet anyone whose fibroid grew using progesterone but

that doesn't mean it can't. [ladies please write back if you have had

growth that you believed is linked to progesterone]

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Ann,

I read a book all about perimenapause -

" What your Doc may not tell you about perimenapause " By Dr.

Lee. Facinating information on the estrogen dominance that happens

to us as we age. (lack of regular ovulation therefore less and less

progesterone) Anyway, to make a long story short, he said to use

this natural progesterone cream to balance the estrogen. I did do

this when I found out I had a fibroid. He even said it could help

shrink fibroids!! I tried it along with his diet & nutrition

stuff. Unfortunately my fibroid did grow a lot bigger and now I am

having a UFE this week. I stopped the cream when I had my 1st

frightening episode with hemmoraging and gushing. I was disapointed

that the cream did not help me. I felt the book made so much sense

and tried his things but I guess it didn't work with me. Jen

-- In uterinefibroids , " donovann70 "

wrote:

> Suzi,

>

> Your doc may well dismiss the information, claiming that info from

> the internet can't be trusted. I do believe that I've posed some

> valid questions though regarding the possible influence of estrone

> versus progesterone in the luteal phase contributing to fibroid

> growth.

>

> They haven't done enough research yet in my mind, not enough to be

> conclusive or to take into account the different life stages we

are

> in and differences between our hormonal situations.

>

> I had two women write back to me about this post (you are the

3rd) --

> one told me that progesterone has helped her tremendously, another

> told me of how using a phytoestrogen gel rapidly grew her fibroid.

I

> have yet to meet anyone whose fibroid grew using progesterone but

> that doesn't mean it can't. [ladies please write back if you have

had

> growth that you believed is linked to progesterone]

>

> Also, consider the fact the progesterone primes the estrogen

> receptors -- that might be why RU-486 works. So, does RU-486 block

> progesterone from doing what it does, or does it block

progesterone

> from helping estrogen do what it does. Chicken or egg -- they

don't

> know.

>

>

> --Ann

>

>

>

> > I might just pass the link onto my gynie and ask him to read it,

as

> > I found it fascinating to say the least. Thanks for the info.

> >

> > Suziedee

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I have posted many many times that I feel my fibroid grew from

progesterone use.

Gerri

> ----- Original Message -----

> From: donovann70

> I

> have yet to meet anyone whose fibroid grew using progesterone

but

> that doesn't mean it can't. [ladies please write back if you

have had

> growth that you believed is linked to progesterone]

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Just yesterday, my Doc gave me a script for Provera. It is pinned to my cork

board. I doubt very much if I will have it filled. My bleed ing is scant to

mod, I cant tell if it is a period, or just bleeding. But, my Hbg is 12.5

today, up from 10 two days ago. Hurray for red wine and one/a/day with iron.

Sue Wolcott, RN

Mt. Shatsa, CA

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