Guest guest Posted February 10, 2004 Report Share Posted February 10, 2004 How do you diagnose hyperammonemia - Is it stool, urine or blood? My son had a stool pH of 8.2 (ref range 6.0-7.2). The doc did not seem to concerned, but it seems that this would encourage bad bugs. Should I do more testing or supplement with something to get the pH down? Thank you, [ ] Re: butyrate vs alpha ketoglutaric acid > , > > Arginine is the standard of treatment for hyperammonemia. The only form of > butyrate that has been proven to work is sodium butyrate so buyer beware. > Also, bicarbonate is critical in the beginning of the urea cycle which is > where ammonia is released. Bicarb is also a major problem for children with > autism and epilepsy. According to Dr.'s Shaw and Baker most autistic > children are extremely low in bicarb which of course would impair ammonia > excretion -- We had excellent results using Cal/mag butyrate for hyperammonemia. Major improvements came very quickly. We also gave bicarbs 90-120 minutes after meals. We don't bother with this any more as our son's hyperammonemia seems to have resolved itself, although we keep some alpha-keto on hand for occasional use. Steve ======================================================= Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2004 Report Share Posted February 10, 2004 , There are a couple of ways. One is a blood draw testing for ammonia, but it has to be processed immediately and correctly otherwise it may give a false elevated reading. Urine organic acid test can give markers that will indicate an elevation in ammonia. That also has to be interpreted correctly. In health, Mark Schauss www.carbonbased.com [ ] Re: butyrate vs alpha ketoglutaric acid > > > > > , > > > > Arginine is the standard of treatment for hyperammonemia. The only > form of > > butyrate that has been proven to work is sodium butyrate so buyer > beware. > > Also, bicarbonate is critical in the beginning of the urea cycle > which is > > where ammonia is released. Bicarb is also a major problem for > children with > > autism and epilepsy. According to Dr.'s Shaw and Baker most autistic > > children are extremely low in bicarb which of course would impair > ammonia > > excretion > > -- We had excellent results using Cal/mag butyrate for > hyperammonemia. Major improvements came very quickly. We also gave > bicarbs 90-120 minutes after meals. > We don't bother with this any more as our son's hyperammonemia seems > to have resolved itself, although we keep some alpha-keto on hand for > occasional use. > > Steve > > > > > ======================================================= > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2004 Report Share Posted February 10, 2004 Is too much ammonia (not enough acid) in the gut bad?? It would seem that an alkaline environment in the gut would hinder the proper digestion of food? Also, not enough acid to kill the gut bugs. [ ] Re: butyrate vs alpha ketoglutaric acid > > > > > , > > > > Arginine is the standard of treatment for hyperammonemia. The only > form of > > butyrate that has been proven to work is sodium butyrate so buyer > beware. > > Also, bicarbonate is critical in the beginning of the urea cycle > which is > > where ammonia is released. Bicarb is also a major problem for > children with > > autism and epilepsy. According to Dr.'s Shaw and Baker most autistic > > children are extremely low in bicarb which of course would impair > ammonia > > excretion > > -- We had excellent results using Cal/mag butyrate for > hyperammonemia. Major improvements came very quickly. We also gave > bicarbs 90-120 minutes after meals. > We don't bother with this any more as our son's hyperammonemia seems > to have resolved itself, although we keep some alpha-keto on hand for > occasional use. > > Steve > > > > > ======================================================= > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2004 Report Share Posted February 10, 2004 Sorry for so many questions, but which OAT test are indicative of this? [ ] Re: butyrate vs alpha ketoglutaric acid > > > > > , > > > > Arginine is the standard of treatment for hyperammonemia. The only > form of > > butyrate that has been proven to work is sodium butyrate so buyer > beware. > > Also, bicarbonate is critical in the beginning of the urea cycle > which is > > where ammonia is released. Bicarb is also a major problem for > children with > > autism and epilepsy. According to Dr.'s Shaw and Baker most autistic > > children are extremely low in bicarb which of course would impair > ammonia > > excretion > > -- We had excellent results using Cal/mag butyrate for > hyperammonemia. Major improvements came very quickly. We also gave > bicarbs 90-120 minutes after meals. > We don't bother with this any more as our son's hyperammonemia seems > to have resolved itself, although we keep some alpha-keto on hand for > occasional use. > > Steve > > > > > ======================================================= > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2004 Report Share Posted February 10, 2004 , Don't ever be shy about asking questions, this how we all get the answers we need for our kids. Orotate (aka orotic acid) is typically elevated in hyperammonemia. Others that would confirm an ammonia problem include Citrate and Isocitrate (elevated). In health, Mark Schauss www.carbonbased.com [ ] Re: butyrate vs alpha ketoglutaric acid > > > > > > > > > , > > > > > > Arginine is the standard of treatment for hyperammonemia. The only > > form of > > > butyrate that has been proven to work is sodium butyrate so buyer > > beware. > > > Also, bicarbonate is critical in the beginning of the urea cycle > > which is > > > where ammonia is released. Bicarb is also a major problem for > > children with > > > autism and epilepsy. According to Dr.'s Shaw and Baker most autistic > > > children are extremely low in bicarb which of course would impair > > ammonia > > > excretion > > > > -- We had excellent results using Cal/mag butyrate for > > hyperammonemia. Major improvements came very quickly. We also gave > > bicarbs 90-120 minutes after meals. > > We don't bother with this any more as our son's hyperammonemia seems > > to have resolved itself, although we keep some alpha-keto on hand for > > occasional use. > > > > Steve > > > > > > > > > > ======================================================= > > Quote Link to comment Share on other sites More sharing options...
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