Re: I have a Question/Kimi

[Guest guest]

Kimi, when I started my chemo over a year and a half ago, I was in class IV Diffuse proliferative, which is considered to be the most serious with the biggest risk of kidney failure. There are actually 6 classes by World Health Organization, but they do not increase in seriousness the higher up the class. It has nothing to do with that. For example: for many years I was considered Class V Membranous Nephritis and not much was done with it, hoping it'll just stay that way. Then I was upgraded in the seriousness to Class IV and put on chemotherapy immediately. I did have proteinuria for years, and big dosses of it, it was not due to a blockage so I wouldn't know much about that. As far as my reactions. Generally I didn't feel much pain in my kidneys, maybe a dull light pain in my back, but not much of it. I was extremely tired and my nerves were shot. My patience was gone, that was all due to the toxins that have not been filtered out of my body. My creatinine was 3.8 when I was put on chemo, but the decision was mainly made based on the kidney biopsy classifying me with Diffuse proliferative glomerular nephritis.

I'm copying the Classifications from Rheumatology.HSS.edu for your information.

the link if you want to look up more is: http://www.rheumatology.hss.edu/pat/eduPrograms/SLE/lupusNephritis.asp

Classification of Nephritis

The World Health Organization classifies kidney problems in the following way:

Class I - A little protein in the urine, with normal filtering function. These patients may need no treatment other than that needed for their other lupus problems.

Class II - Mesangial change in one area of the glomeruli - The mesangium is the structure that holds up the filtering units in the kidneys. In this class, there are some changes in one area of those units. Depending on how fast those changes are developing, the doctor may want to start treatment.

Class III - Active inflammation but in a patchy fashion with some areas remaining normal. The doctor wants to give advice on treatment

Class IV - Diffuse proliferative glomerular nephritis - Virtually all of the kidney is involved in inflammation.

Class V - Membranous nephritis- New deposits have gotten stuck on the filtering membrane and have not elicited an inflammatory response - The doctor may decide to leave it alone and watch it or to treat it intermittently.

Class VI - Advanced sclerosing (scarring) - The disease is beyond the point where it can be treated with the anti-inflammatory or immunosuppressant medications that normally help lupus. Instead, we treat with medications to try to prevent further scarring, which may or may not work.

I have a Question

Hi everyone!!!! Hope everyone had a beautiful Sunday. I know I did. Ok my creatine (SP) keeps on getting higher and higher my doctor is worried about it he called me himself last week. Because I am not spilling any portien he thinks I might have a blockage somewhere. I had to get more blood work done on friday I will get my results tomorrow and if it is the same or higher i will have to get a ultrasound which i am almost positive i will ended getting a ultrasound done. I am really nervsous about this cause to me it means that the lupus is active again in my kidenys ok here is my question if i do have blockage wouldn't I be hurting somewhere? that is one thing that has me puzzled. I don't know if anyone has this problem or had it but i am really scared I know i am in stage 3 of lupus in my kidenys and from what i am told there are only 4 stage of lupus in the kidneys so yes i am scared of going tomorrow cause i don't know really what i am going into or i should say i don't know how bad i am getting into this. Any kind of anwser will help me out alot I really do appreciate anything here. Everyone is in my thoughts and prayers. I am so happy for you that you finally got some sunshine up there and no cold weather it was hot has hell here today we went out in the woods on the fourwheeler we had a blast came back all dirty but oh well and yes i did cover up with sunscreen i just go wind burnt is all. ok i know i am boring everyone by now so i will let everyone go.

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