[edsaware] Re: article on EDS and osteoporosis

[Guest guest]

Please be aware that Dr. Atul Deodhar's research on EDS and Osteoporosis was

a small study and did not adjust for age, weight, smoking, and other factors

related to osteoporosis risk. I have spoken with him personally about his

study and he admits that the research by Dr. Carbone is more in-depth

and more accurate. Dr. Carbone's study adjusted the results for other risk

factors and found that people with EDS are prone to osteoporosis not because

of EDS itself, but rather due to other factors, such as lack of exercise.

This is logical, as many EDSers do not get adequate exercise because of

fears of joint injury.

Both articles were published in EDS Today, Spring-Summer 2001

http://www.edstoday.org/newsletter/SS2001.htm

Abstract

Osteoporos Int. 2000;11(5):388-92. Related Articles, Links

Bone density in Ehlers-Danlos syndrome.

Carbone L, Tylavsky FA, Bush AJ, Koo W, Orwoll E, Cheng S.

Department of Medicine, University of Tennessee, Memphis 38163, USA.

Ehlers-Danlos Syndrome (EDS) is the most common inherited disorder of

connective tissue recognized. The objectives of the present study were to

determine bone mineral density (BMD) and biochemical markers of bone

metabolism in EDS. Twenty-three subjects with Type III EDS and 23 matched

controls underwent BMD measurement by dual-Energy X-ray absorptiometry (DXA)

of the lumbar spine and femoral neck. Health history questionnaires and

biochemical markers of bone and connective tissue metabolism were also

assessed. No significant differences in BMD at the lumbar spine or

differences in biochemical markers of bone and connective tissue metabolism

were found between EDS subjects and controls. EDS subjects had a

significantly decreased BMD at the femoral neck compared with controls, but

this difference disappeared after adjustment for body height, weight and

physical activity levels.

PMID: 10912839 [PubMed - indexed for MEDLINE]

[Guest guest]

> Thanks for this information, Barb! Boy, your household must have

> lots of interesting discussions, as knowledgeable as you all are!

What makes you think we talk to each other? : ) Kerry and I are too busy

in school. I email and IM more with my parents than I speak to them, even

though they live downstairs!

-Barb

[Guest guest]

> > Thanks for this information, Barb! Boy, your household must have

> > lots of interesting discussions, as knowledgeable as you all

are!

>

> What makes you think we talk to each other? : ) Kerry and I are

too busy

> in school. I email and IM more with my parents than I speak to

them, even

> though they live downstairs!

>

> -Barb

Sounds like MOST busy families these days! Computers/email are

sometimes both a blessing and a curse.