Re: Clinical Trial at NIH--RH and genetic testing

[Guest guest]

Here's a quote from Dr. Vladutiu on the yield of genetic testing in

respiratory chain disorders: " I predict that only in a minority of

cases will we be fortunate enough to find a single gene defect

(mitochondrial DNA or nuclear DNA) that is causative. In fact, in a

published study of 2,000 specimens referred for mtDNA mutation

analysis, Dr. Lee-Jun Wong's laboratory found a causative mutation

in under 7%. This ballpark yield in large-scale studies has been

echoed in at least 2 other laboratories. "

Source: http://www.rgbgl.org/research/respiratorychain.htm

Barbara

> >

> > Thanks Ruth for bringing this to my attention.

> >

> > http://clinicaltrials.gov/ct/show/NCT00025870?order=4

> >

> > Alice