Re: Tracey - Skyler/Barb-clobazam/sleep

[Guest guest]

The major problem with benzodiazapines (and barbiturates actually like

phenobarb) for sleep is that although they can lengthen the time asleep, the

quality of sleep 'changes', in that the periods of REM and non REM sleep

alter. Most epileptics are more prone to seizures in non REM sleep, and as

these periods are longer when on benzos, (the duration of deep REM sleep on

these meds usually reduces, though sometimes a tolerance to this develops

over time and sleep patterns can revert back to normal) there is more time

therefore 'available' for those mom REM sleep seizures to be induced.

Also, there are very few benzos (actually, none...) whose 'active' half

life is sufficient to carry right through till the next morning, meaning

that the risk of inter dose mini withdrawal seizures increases, and with

keto kids, this is usually the time that ketones are at their lowest, so

with the least protection against them.

The 'non active' half life of a lot of these meds is longer, meaning the

hung over sedative effect is still present on waking and can then accumulate

with the next dose (nitrazepam is one of the worst offenders here, but it

applies to a certain degree to most benzos..)

's early am sleep seizures disappeared soon after his regular AED

diazepam was ditched, (first time in over 3 yrs he stoped having them, first

time in over 3 yrs he has not been on a benzo...) but at the same time he

also started having higher early am ketones, so not sure which one did it,

possibly both in combination.

----- Original Message -----

> and then will begin w/the Clobazam

> wean

nocturnal seizures when the sole purpose of our adding it was for the

sleep

> attacks!>.

>

>

> Hi Tracey,

> Wondering more about this. We have the Clobozam here but have not

started it. Also have not finished reading the articles! We put the Keppra

back and it's helping with the drops....but we are plagued daily by the

early morning grand mals. Clobazam can make them worse? Oh great....

> Barb Swoyer

[Guest guest]

The major problem with benzodiazapines (and barbiturates actually like

phenobarb) for sleep is that although they can lengthen the time asleep, the

quality of sleep 'changes', in that the periods of REM and non REM sleep

alter. Most epileptics are more prone to seizures in non REM sleep, and as

these periods are longer when on benzos, (the duration of deep REM sleep on

these meds usually reduces, though sometimes a tolerance to this develops

over time and sleep patterns can revert back to normal) there is more time

therefore 'available' for those mom REM sleep seizures to be induced.

Also, there are very few benzos (actually, none...) whose 'active' half

life is sufficient to carry right through till the next morning, meaning

that the risk of inter dose mini withdrawal seizures increases, and with

keto kids, this is usually the time that ketones are at their lowest, so

with the least protection against them.

The 'non active' half life of a lot of these meds is longer, meaning the

hung over sedative effect is still present on waking and can then accumulate

with the next dose (nitrazepam is one of the worst offenders here, but it

applies to a certain degree to most benzos..)

's early am sleep seizures disappeared soon after his regular AED

diazepam was ditched, (first time in over 3 yrs he stoped having them, first

time in over 3 yrs he has not been on a benzo...) but at the same time he

also started having higher early am ketones, so not sure which one did it,

possibly both in combination.

----- Original Message -----

> and then will begin w/the Clobazam

> wean

nocturnal seizures when the sole purpose of our adding it was for the

sleep

> attacks!>.

>

>

> Hi Tracey,

> Wondering more about this. We have the Clobozam here but have not

started it. Also have not finished reading the articles! We put the Keppra

back and it's helping with the drops....but we are plagued daily by the

early morning grand mals. Clobazam can make them worse? Oh great....

> Barb Swoyer

[Guest guest]

, I am amazed at your enormous knowledge of all things keto.

Where have you learned it all from?

And did you try a blueberry muffin or almond cake for yet???

Take care

, Mum to Francesca, Keto Kid since Sept 03, drug free since May

04

> The major problem with benzodiazapines (and barbiturates actually

like

> phenobarb) for sleep is that although they can lengthen the time

asleep, the

> quality of sleep 'changes', in that the periods of REM and non REM

sleep

> alter. Most epileptics are more prone to seizures in non REM sleep,

and as

> these periods are longer when on benzos, (the duration of deep REM

sleep on

> these meds usually reduces, though sometimes a tolerance to this

develops

> over time and sleep patterns can revert back to normal) there is

more time

> therefore 'available' for those mom REM sleep seizures to be

induced.

> Also, there are very few benzos (actually, none...)

whose 'active' half

> life is sufficient to carry right through till the next morning,

meaning

> that the risk of inter dose mini withdrawal seizures increases, and

with

> keto kids, this is usually the time that ketones are at their

lowest, so

> with the least protection against them.

> The 'non active' half life of a lot of these meds is longer,

meaning the

> hung over sedative effect is still present on waking and can then

accumulate

> with the next dose (nitrazepam is one of the worst offenders here,

but it

> applies to a certain degree to most benzos..)

> 's early am sleep seizures disappeared soon after his

regular AED

> diazepam was ditched, (first time in over 3 yrs he stoped having

them, first

> time in over 3 yrs he has not been on a benzo...) but at the same

time he

> also started having higher early am ketones, so not sure which one

did it,

> possibly both in combination.

>

>

>

> ----- Original Message -----

> From: " Barbara Swoyer "

>

> > and then will begin w/the Clobazam

> > wean

worsening

> > nocturnal seizures when the sole purpose of our adding it was

for the

> sleep

> > attacks!>.

> >

> >

> > Hi Tracey,

> > Wondering more about this. We have the Clobozam here but have

not

> started it. Also have not finished reading the articles! We put

the Keppra

> back and it's helping with the drops....but we are plagued daily by

the

> early morning grand mals. Clobazam can make them worse? Oh

great....

> > Barb Swoyer

[Guest guest]

, I am amazed at your enormous knowledge of all things keto.

Where have you learned it all from?

And did you try a blueberry muffin or almond cake for yet???

Take care

, Mum to Francesca, Keto Kid since Sept 03, drug free since May

04

> The major problem with benzodiazapines (and barbiturates actually

like

> phenobarb) for sleep is that although they can lengthen the time

asleep, the

> quality of sleep 'changes', in that the periods of REM and non REM

sleep

> alter. Most epileptics are more prone to seizures in non REM sleep,

and as

> these periods are longer when on benzos, (the duration of deep REM

sleep on

> these meds usually reduces, though sometimes a tolerance to this

develops

> over time and sleep patterns can revert back to normal) there is

more time

> therefore 'available' for those mom REM sleep seizures to be

induced.

> Also, there are very few benzos (actually, none...)

whose 'active' half

> life is sufficient to carry right through till the next morning,

meaning

> that the risk of inter dose mini withdrawal seizures increases, and

with

> keto kids, this is usually the time that ketones are at their

lowest, so

> with the least protection against them.

> The 'non active' half life of a lot of these meds is longer,

meaning the

> hung over sedative effect is still present on waking and can then

accumulate

> with the next dose (nitrazepam is one of the worst offenders here,

but it

> applies to a certain degree to most benzos..)

> 's early am sleep seizures disappeared soon after his

regular AED

> diazepam was ditched, (first time in over 3 yrs he stoped having

them, first

> time in over 3 yrs he has not been on a benzo...) but at the same

time he

> also started having higher early am ketones, so not sure which one

did it,

> possibly both in combination.

>

>

>

> ----- Original Message -----

> From: " Barbara Swoyer "

>

> > and then will begin w/the Clobazam

> > wean

worsening

> > nocturnal seizures when the sole purpose of our adding it was

for the

> sleep

> > attacks!>.

> >

> >

> > Hi Tracey,

> > Wondering more about this. We have the Clobozam here but have

not

> started it. Also have not finished reading the articles! We put

the Keppra

> back and it's helping with the drops....but we are plagued daily by

the

> early morning grand mals. Clobazam can make them worse? Oh

great....

> > Barb Swoyer