Re: Barb/Tracey - Clobazam anyone?

[Guest guest]

Hmm, for , klonipin (clonaz) was the opp, it hyped him up, (but without

positive seizure benefit so even that didn't help here) and clobazam turned him

into a slug; diaz was kind of in between, and nitrazepam (mogadon) - well, as it

is primarily a sleeping tab, I don't need to expand on how that one affected him

However, is one of those kids where meds like the sedating

anthistamines did the opp to him - he used to turn into a livewire on them, so

I suppose indivdual metabolisms comes into play as well.

From what I gather, there are no benzos with an 'active' half life long enough

to get away with once a day dosing - we tried night only for a while with

too, but we ran into too many problems the next day as his blood level dropped

back down, like a mini withdrawal phase each day till his next dose started

peaking again. Do you not see that with Skyler?

How is he doing overall at the mo?

----- Original Message -----

From: tflourie@...

Barb-

As you know, Skyler is on Clobazam...40 mgs (and he's about 135 lbs). This

is our third go-round on it and yes, weaning is awful and yes, patients

develop tolerance.

For him, it was a blessing of a benzo...as it is ~60% less sedating than

most of the benzo's used for AED's (Klonopin, Tranxene). Those drugs

actually

exacerbated his seizures due to the sedation.

We have always dosed his Clobazam at night...just thinking you might try

that w/Jake and see is he's less sedated.

I wish I could remember the dose we started Skyler on (when he was 6, I

think), but the old brain cells (MINE!!) just don't fire like they used to.

Wishing you the best...

Tracey