Guest guest Posted April 2, 2006 Report Share Posted April 2, 2006 I knew that I read about Sotalol and the kidneys, but, as below, it doesn't damage the kidney, but the dosage needs to be less if the kidneys are damaged because Sotalol would stay in the body longer then. (There was a similar situation with Atenolol, which my husband had been taking earlier.) Re: Sotalol-- " Excretion is predominantly via the kidney in the unchanged form, and therefore lower doses are necessary in conditions of renal impairment. Age per se does not significantly alter the pharmacokinetics of sotalol, but impaired renal function in geriatric patients can increase the terminal elimination half-life, resulting in increased drug accumulation. " http://www.drugs.com/pdr/SOTALOL_HYDROCHLORIDE.html So the relationship between Solatol and the kidney is if that if kidney function is impaired, Sotalol is held in the body longer and the dosage should be less. Shouldn't there be a test to check kidney function before giving Sotalol and again from time to time to see if it has become impaired? - - - (Here's the information for Atenolol that works similarly to Sotalol re the kidney and, in particular, the creatinin level is what should be tested. http://www.drugs.com/pdr/atenolol.html) Jo Anne Re: Sotalol causing renal damage... I think not Dear Everyone I have never heard of sotalol causing renal damage. It is important to check for sotalol levels in people with renal failure because the drug is excreted by the kidneys and a little in the faeces. If you do not check the levels of the drug in the blood the levels maybe come toxic and the worst thing the patient may develop is a very very slow pulse. I am aware that the drug may cause potassium and magnesium levels in the blood to drop (makes it important to take magnesium supplements) but I do not know of any other thing that the drugs does to kidney function. Is the doctor checking renal function because he thinks the person had some renal impairment and this will determine how much sotalol he can give to the patient. Regards Lynda Loretta cleaner@...> wrote: I am on Sotalol and was taking Norvasc before my Sotalol was doubled. I asked my cardiologist if I needed labs to check my kidney/liver function and he said that taking Advil was more damaging to my kidneys than what I am taking. I do get blood work annually, but are the rest of you on antiarrhythmics having labs more often? Loretta Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.