Guest guest Posted December 3, 2004 Report Share Posted December 3, 2004 I'll take a stab at this. Your parathyroid glands make parathyroid hormone which tells your kidneys to make a hormone called Calcitrol which helps to regulate the levels of calcium and phosphorus in your blood. When your kidneys no longer make enough of that hormone, it causes the parathyroid gland to work overtime making more parathyroid hormone in an effort to tell the kidneys they need to make more calcitrol. However, when your kidney function is too low, and no longer able to make enough Calcitrol, the high levels of parathyroid hormone (PTH) in your blood causes your body pulls calcium and phosphorus out of bones. One of the other functions of PTH is to tell your kidneys to get rid of the excess phosphorus in your kidneys, and when your kidneys no longer can do that, the levels of phosphorus also build up hence the need for low phosphorus diets. This high level of PTH over time leads the bones becoming brittle and weak due to the calcium and phosphorus levels being out of whack, and can also lead to renal osteodystrophy in addition to causing itching and bone and joint pain among other things. Hope this makes sense! In a message dated 12/3/2004 6:33:27 PM Pacific Standard Time, cyashleywebb@... writes: > Hi , > When you have a moment, can you please explain the connection between bone > pain and parathyroid hormone? You're (as usual!) one up on me with that > one. > Cy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 3, 2004 Report Share Posted December 3, 2004 Thanks . I appreciate your taking the time on this one! This post is a real keeper. Cy Re: Parathyroid hormone > > I'll take a stab at this. Your parathyroid glands make parathyroid hormone > which tells your kidneys to make a hormone called Calcitrol which helps to > regulate the levels of calcium and phosphorus in your blood. When your kidneys no > longer make enough of that hormone, it causes the parathyroid gland to work > overtime making more parathyroid hormone in an effort to tell the kidneys they > need to make more calcitrol. However, when your kidney function is too low, > and no longer able to make enough Calcitrol, the high levels of parathyroid > hormone (PTH) in your blood causes your body pulls calcium and phosphorus out of > bones. One of the other functions of PTH is to tell your kidneys to get rid > of the excess phosphorus in your kidneys, and when your kidneys no longer can > do that, the levels of phosphorus also build up hence the need for low > phosphorus diets. > > This high level of PTH over time leads the bones becoming brittle and weak > due to the calcium and phosphorus levels being out of whack, and can also lead > to renal osteodystrophy in addition to causing itching and bone and joint pain > among other things. > > Hope this makes sense! > > > > In a message dated 12/3/2004 6:33:27 PM Pacific Standard Time, > cyashleywebb@... writes: > > > Hi , > > When you have a moment, can you please explain the connection between bone > > pain and parathyroid hormone? You're (as usual!) one up on me with that > > one. > > Cy > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2004 Report Share Posted December 4, 2004 That's a pretty good stab . It seems like everytime I talk to someone at dialysis, they are having or have had their parathyroids out. One guy even had to have his out months after having had a successful kidney transplant - but he had been on dialysis for 5 years prior to that. Mine are Ok so far though. Once the numbers can no longer be managed with diet and medication, the paras have to come out. A reasonably quick kidney transplant can prevent this from happnening, but it's not a guarantee. Pierre Re: Parathyroid hormone > > I'll take a stab at this. Your parathyroid glands make parathyroid hormone > which tells your kidneys to make a hormone called Calcitrol which helps to > regulate the levels of calcium and phosphorus in your blood. When your kidneys no > longer make enough of that hormone, it causes the parathyroid gland to work > overtime making more parathyroid hormone in an effort to tell the kidneys they > need to make more calcitrol. However, when your kidney function is too low, > and no longer able to make enough Calcitrol, the high levels of parathyroid > hormone (PTH) in your blood causes your body pulls calcium and phosphorus out of > bones. One of the other functions of PTH is to tell your kidneys to get rid > of the excess phosphorus in your kidneys, and when your kidneys no longer can > do that, the levels of phosphorus also build up hence the need for low > phosphorus diets. > > This high level of PTH over time leads the bones becoming brittle and weak > due to the calcium and phosphorus levels being out of whack, and can also lead > to renal osteodystrophy in addition to causing itching and bone and joint pain > among other things. > > Hope this makes sense! > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2004 Report Share Posted December 4, 2004 Good morning Pierre, You are right and I forgot to mention that my Neph told me that the parathyroids almost always do have to come out sooner or later with chronic renal failure. Our little kidneys are such important organs and do so much more than just make urine. My PTH is already more than double what it should be, but I still have been spared the itching thank goodness. In a message dated 12/4/2004 10:25:21 AM Eastern Standard Time, " Pierre Lachaine " writes: > >That's a pretty good stab . > >It seems like everytime I talk to someone at dialysis, they are having or >have had their parathyroids out. One guy even had to have his out months >after having had a successful kidney transplant - but he had been on >dialysis for 5 years prior to that. Mine are Ok so far though. > >Once the numbers can no longer be managed with diet and medication, the >paras have to come out. A reasonably quick kidney transplant can prevent >this from happnening, but it's not a guarantee. > >Pierre > > Re: Parathyroid hormone > > >> >> I'll take a stab at this. Your parathyroid glands make parathyroid >hormone >> which tells your kidneys to make a hormone called Calcitrol which helps to >> regulate the levels of calcium and phosphorus in your blood. When your >kidneys no >> longer make enough of that hormone, it causes the parathyroid gland to >work >> overtime making more parathyroid hormone in an effort to tell the kidneys >they >> need to make more calcitrol. However, when your kidney function is too >low, >> and no longer able to make enough Calcitrol, the high levels of >parathyroid >> hormone (PTH) in your blood causes your body pulls calcium and phosphorus >out of >> bones. One of the other functions of PTH is to tell your kidneys to get >rid >> of the excess phosphorus in your kidneys, and when your kidneys no longer >can >> do that, the levels of phosphorus also build up hence the need for low >> phosphorus diets. >> >> This high level of PTH over time leads the bones becoming brittle and weak >> due to the calcium and phosphorus levels being out of whack, and can also >lead >> to renal osteodystrophy in addition to causing itching and bone and joint >pain >> among other things. >> >> Hope this makes sense! >> >> >> > > > > > >To edit your settings for the group, go to our Yahoo Group >home page: >http://groups.yahoo.com/group/iga-nephropathy/ > >To unsubcribe via email, >iga-nephropathy-unsubscribe >Visit our companion website at www.igan.ca. The site is entirely supported by donations. If you would like to help, go to: >http://www.igan.ca/id62.htm > >Thank you > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 8, 2004 Report Share Posted December 8, 2004 This is good one , I am gonna save it Thanks Aruna --- W4JC@... wrote: > I'll take a stab at this. Your parathyroid glands > make parathyroid hormone > which tells your kidneys to make a hormone called > Calcitrol which helps to > regulate the levels of calcium and phosphorus in > your blood. When your kidneys no > longer make enough of that hormone, it causes the > parathyroid gland to work > overtime making more parathyroid hormone in an > effort to tell the kidneys they > need to make more calcitrol. However, when your > kidney function is too low, > and no longer able to make enough Calcitrol, the > high levels of parathyroid > hormone (PTH) in your blood causes your body pulls > calcium and phosphorus out of > bones. One of the other functions of PTH is to tell > your kidneys to get rid > of the excess phosphorus in your kidneys, and when > your kidneys no longer can > do that, the levels of phosphorus also build up > hence the need for low > phosphorus diets. > > This high level of PTH over time leads the bones > becoming brittle and weak > due to the calcium and phosphorus levels being out > of whack, and can also lead > to renal osteodystrophy in addition to causing > itching and bone and joint pain > among other things. > > Hope this makes sense! > > > > In a message dated 12/3/2004 6:33:27 PM Pacific > Standard Time, > cyashleywebb@... writes: > > > Hi , > > When you have a moment, can you please explain the > connection between bone > > pain and parathyroid hormone? You're (as usual!) > one up on me with that > > one. > > Cy > > > > [Non-text portions of this message have been > removed] > > __________________________________________________ Quote Link to comment Share on other sites More sharing options...
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