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Re: HepB titer level question

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Hi Debi,

We have had our son's HepB titer measured 2x in the past couple of years. The

test says " Hep B Surface Antibody " and values >10 have been reported by the CDC

to be consistent with immunity to Hepatitis B. Ours was drawn through Pfeiffer

Treatment Center and the lab they used for this test was Laboratory Corporation

of America.

Good Luck,

[ ] HepB titer level question

I took Allie for her well visit today. He agreed to all my test

request and wrote out orders. When I asked about HepB titer level

check, he told me there is no way to check the level, only if there

is a presence of antibody or not. Is this true? I find it hard to

believe, esp when I told him that I wanted to check it because that

is when she regressed. He probably is also aware by now that I've

filed for vaccine compensation, even though he was not the ped at

the time.

If there is a specific test, what is the technical order for it?

TIA,

Debi

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SO they do give a number and a reference range? That's what I

thought! That misleader!

Debi

> Hi Debi,

>

> We have had our son's HepB titer measured 2x in the past couple of

years. The test says " Hep B Surface Antibody " and values >10 have

been reported by the CDC to be consistent with immunity to Hepatitis

B. Ours was drawn through Pfeiffer Treatment Center and the lab

they used for this test was Laboratory Corporation of America.

>

> Good Luck,

>

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> I took Allie for her well visit today. He agreed to all my test

> request and wrote out orders. When I asked about HepB titer level

> check, he told me there is no way to check the level, only if there

> is a presence of antibody or not.

Then I would ask him for this test, to see if antibody is present. If

it comes back with the level, then both of you will be pleasantly

surprised. If it does not, but indicates presence of antibodies, then

perhaps you can use that result to request your medical exemption.

Dana

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I would love to hear how you resolve this. My daughter will come due

for a booster in a few years. Thanks.

---

In , " Debi " <fightingautism@y...>

wrote:

> I took Allie for her well visit today. He agreed to all my test

> request and wrote out orders. When I asked about HepB titer level

> check, he told me there is no way to check the level, only if there

> is a presence of antibody or not. Is this true? I find it hard to

> believe, esp when I told him that I wanted to check it because that

> is when she regressed. He probably is also aware by now that I've

> filed for vaccine compensation, even though he was not the ped at

> the time.

>

> If there is a specific test, what is the technical order for it?

>

> TIA,

> Debi

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A yr ago they told my hiv nephew to get hep -b he did.

So where is it?Appears his body ate it. My take is

theyve all been set up for cancer or hiv. He has no

hep- b in him according to the test.

--- Tim & Owczarzak <owczarzak@...> wrote:

> Hi Debi,

>

> We have had our son's HepB titer measured 2x in the

> past couple of years. The test says " Hep B Surface

> Antibody " and values >10 have been reported by the

> CDC to be consistent with immunity to Hepatitis B.

> Ours was drawn through Pfeiffer Treatment Center and

> the lab they used for this test was Laboratory

> Corporation of America.

>

> Good Luck,

>

> [ ] HepB titer level

> question

>

>

> I took Allie for her well visit today. He agreed

> to all my test

> request and wrote out orders. When I asked about

> HepB titer level

> check, he told me there is no way to check the

> level, only if there

> is a presence of antibody or not. Is this true? I

> find it hard to

> believe, esp when I told him that I wanted to

> check it because that

> is when she regressed. He probably is also aware

> by now that I've

> filed for vaccine compensation, even though he was

> not the ped at

> the time.

>

> If there is a specific test, what is the technical

> order for it?

>

> TIA,

> Debi

>

>

>

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Robbie,

Saying you have titres means that you still are producing antibodies to

something, so if you have zero titres, that means you are not making

antibodies specific to that germ.

I don't exactly have good news about this, but there is a haplotype

(genetic difference) that makes it impossible for some people to make

antibodies to the hepatitis B surface antigen that is in the

vaccine. Exposure to the hep B vaccine is probably very bad for people

with this HLA A1-B8-DR3 haplotype and especially if they have HIV. The

problem is that their intracellular molecules that are supposed to hold

antigen have trouble binding this antigen enough to carry it to the cell

surface where it can be recognized by other immune cells that will initiate

the first steps to the antibody-making process.

Please write me offlist, and I will give you some posts I wrote on this

many years ago when I realized that the population given the Hep B was in

the same risk category as the people who are at risk for HIV, which means

they were some of the first people to actually be given this new vaccine

about twenty years ago before it became mandatory for children. The use of

the HepB vaccine, and the onslaught of the AIDS epidemic came at the same

time in our country. The AIDS epidemic in Africa came on the wings of a

huge World Health Organization program to immunize Africa for many

things. (I would guess they may have vulnerable haplotypes to other

germs/antigens that their ancestors in Africa were not exposed to...but

probably not the HepB...something else.)

The literature says that this particular haplotype (A1-B8-DR3) is commonly

known to be especially at risk for HIV infection turning into AIDS. This

haplotype is very common: one of the most prevalent haplotypes in those who

are descended from ancestors from England, Scotland, Ireland, and parts of

Northern Europe.

There may be a reasonable defence against this conversion into AIDS if your

nephew will work hard at enhancing his sulfur chemistry. There has been a

huge amount of research done on this in Germany, and I would be glad to

share that with you if you will write offlist.

At 07:39 PM 9/12/2003 -0700, you wrote:

>A yr ago they told my hiv nephew to get hep -b he did.

>So where is it?Appears his body ate it. My take is

>theyve all been set up for cancer or hiv. He has no

>hep- b in him according to the test.

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Well, the issue is already resolved. She won't be having any more

vaccines.

Debi

> I would love to hear how you resolve this. My daughter will come

due

> for a booster in a few years. Thanks.

>

> -

--

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Robbie,

Do you have anyone in your family with celiac disease, or dermatitis

herpetiformis, hepatitis, Sjogren's syndrome, congenital rubella, systemic

sclerosis, AIDS, CMV infection or IgA deficiency? People with the set of

immunological genes, HLA A1 B8 DR3 are at increased risk to the hepatitis

vaccine and to developing the listed conditions. Part of the problem may

come from the associated TNF gene which makes you make too much TNF. TNF

really gets inflammation going in a big way, which sounds like what

happened in your children.

Clin Exp Immunol. 1993 Apr;92(1):14-8. Related Articles, Links

Polymorphic MHC ancestral haplotypes affect the activity of tumour

necrosis factor-alpha.

Abraham LJ, French MA, Dawkins RL.

Department of Clinical Immunology, Royal Perth Hospital, Australia.

It remains unclear which MHC loci are involved in susceptibility to

autoimmune diseases and immune deficiencies. We have chosen to evaluate

whether different alleles of tumour necrosis factor-alpha (TNF-alpha) are

important, as TNF has been implicated in the etiology of many immunological

disorders. We have shown previously that a restriction fragment length

polymorphism in the TNF region correlates with MHC ancestral haplotypes. We

therefore examined the effect of ancestral haplotype on the activity of

TNF-alpha in culture supernatants of lymphoblastoid cell lines. The results

demonstrate that TNF-alpha activity in supernatants of 8.1 (A1, B8, DR3)

cell lines was higher than that present in the supernatants from cells

homozygous for eight different MHC ancestral haplotypes, and indicate that

polymorphisms in TNF-alpha, or in other MHC genes that regulate TNF, may be

responsible for the 8.1 phenotype.

PMID: 8096802 [PubMed - indexed for MEDLINE]

Med J Aust. 2002 Dec 2-16;177(11-12):664-7. Related Articles, Links

[Click here to read]

Gregg's congenital rubella patients 60 years later.

Forrest JM, Turnbull FM, Sholler GF, Hawker RE, FJ, Doran TT,

Burgess MA.

Royal andra Hospital for Children, Locked Bag 4001, Westmead, NSW.

jillf@...

BACKGROUND: In 1941, a Sydney ophthalmologist, Norman McAlister Gregg,

correctly identified the link between congenital cataracts in infants and

maternal rubella early in pregnancy. Fifty of Gregg's subjects with

congenital rubella, born in 1939-1944, were reviewed in 1967 and again in

1991. We reviewed this cohort in 2000-2001, 60 years after their

intrauterine infection. METHODS: The subjects underwent full clinical

assessment, plus pathology tests, an ophthalmological and cardiological

review (including electrocardiography and echocardiography) and HLA

histocompatibility testing. RESULTS: Since they were first seen in 1967, 10

have died (cardiovascular causes [4], malignant disease [4], AIDS [1], and

hepatitis C-related cirrhosis [1]). All surviving men came for review (19)

and 13 women (eight women declined). Echocardiography showed mild aortic

valve sclerosis in 68%. The prevalence of diabetes (22%), thyroid disorders

(19%), early menopause (73%) and osteoporosis (12.5%) was increased

compared with the Australian population; 41% had undetectable levels of

rubella antibodies. The frequency of HLA-A1 (44%) and HLA-B8 (34%) antigens

was increased, and the haplotype HLA-A1, B8, DR3, said to be highly

associated with many autoimmune conditions, was present in 25%.

CONCLUSIONS: This cohort of people with congenital rubella has illuminated

our understanding of viral teratogenesis.

Publication Types:

* Biography

* Historical Article

Personal Name as Subject:

* Gregg NM

At 06:49 PM 9/12/2003 -0700, you wrote:

>Hep -B is infamous for brain swelling and they know

>it. Just tell them to take it themselfs. Assure them

>your child is not attanding an orgie with lots of

>i.v.drugs. My first kid[typical with 1 sensory issue ]

>went into resp distress ,suffered brain swelling and

>some seizure like activity. 40 min. after hep -b. Fast

>forward 2nd child asd with brain herniation[which is

>end result of brain swelling not treated] kid # 1

>spent 10 days in hosp. got under controll. Kid 2

>should have never been given hep-b shot!Had mild resp.

>problems they told me was asthma[funny it disappeared

>when no more shots were given]But is left w/a brain

>herniation from the swelling. Tell the m.ds to screw!

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