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HELP Please PXR Rifampin?--- pruritus-- UK Tim

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To be

honest Tim, I would not worry too much about the Rifampin too much if at

all. There are studies that are on the PSC Literature site that

keeps up for us that it flips some switch on the genes I think…PXR or

something…but I can’t find it. probably knows exactly

what I mean and could find it for you toute suite but I can’t. And

I can’t remember what the benefit is either, so am I worthless today or


And yes the general population should not

be on a long term antibiotic, but I don’t know if those rules apply for

PSCers. I am not taking Noah off of it because of preconceived ideas like

that. No itch Noah has had is worth taking him off. His hands and

feet were so bad at one point he would bleed and we are so not going

back. Keep in mind, some PSCers take daily meds to prevent cholangitis


This is just my 2 cents and hopefully

others will pipe up with theirs.


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