Re: Need to pick brains on my med tweaking - only for the brave - and it's LLOONNGG!!! hehehehe

June 15, 2005

, have you been tested for insulin and glucose? Insulin

resistance can cause weakness and fatigue. Insulin resistance can

cause obesity and obesity can cause insulin resistance. I'm so tired

after working in the heat all day, I figure I better not comment

about anything you said here until I'm rested.

Chris

> Okay, I know what I WANT to do.. and it would work.. and I know

what I

> should do, but am not sure it would work. Now that I have you all

> confused... wait until you see the res!!!!

>

> ... maybe a seat belt and crash helmet are in order. For sure grab a

> paper an pencil to take notes!!! hehehehee

>

> I have to set up pill boxes tomorrow morning... so the sooner we can

> figure this out.. the better... If we can't.. I'll keep it all the

same

> as it is right now until we come up with an idea as to what my body

is

> trying to tell me.

>

> We all know how hard it is to see yourself sometimes.. and this one

has

> been bugging me.. not knowing quite what I need to shift.

>

> Brief history part.

> RAI about 15 years ago, no thyroid function. Genetic defect, not

> autoimmune, disease or injury.

> Synthroid and it's clones prescribed by docs, maximum dose never

exceeded

> 200 mcg. Ended up needed crutches to walk, ran out of Synthetic T4

and

> money for docs, labs and meds in November '99.

> Got intermittent 'left over' pills from friends an relatives between

> spring '00 to July '02. Basals dropped to temp of 97.0 or slightly

less,

> pulse of 50 and respiration of 10 and now realize I was also

dealing with

> 'air hunger'

> Started self medicating in July '02 with OTC natural, started

> prescription grade natural in July '03.

> My body is very sensitive to adjustments and dosing. Adjustments

are best

> done at 6 to 8 weeks, some have been as long as 12. I find that I

need to

> dose throughout the day, with the final dose at bedtime. Otherwise

I have

> fatigue issues.

>

> Had labs done in Feb '05

> TSH .333 ( .35 - 5.50 ) -- I know range is wrong...

> Free T4 .9 ( .8 - 1.8 )

> Free T3 2.9 ( 2.3 - 4.2 )

>

> Based on these labs, and symptoms I determined I needed to increase.

> Basals were up: Temp 98.2 to 98.4, pulse between 72 and 78,

respiration

> at 18 to 20.

>

> Financial considerations had me choose to maintain my current dose

of

> natural (I had been on this dose since April of '04, holding at the

same

> dose until I could get a ride in for labs), 7 doses of 1/2 grain

per day,

> for a total of 3 1/2 grain per day, taken sublingually. . And use

> synthetic to do my increases. This was done to stretch the stash of

> natural that I have until I can find another source.

> T4 equivalent of 259 mcg

>

> The first increase was to add 25 mcg of T4, taken first thing in the

> morning, empty stomach, along with my first 1/2 dose of natural and

my

> dose of desiccated adrenal, taken sublingually. The rest of my daily

> thyroid schedule remained the same. I didn't notice much of a

> difference.. no 'WHAM' but I had the uncomfortableness that I get

with a

> change in dosage.

> T4 equivalent of 284 mcg

>

> I was stupid, impatient and a smart A & ^% and increased another 25

mcg of

> T4 after 12 days. This hit me a bit harder and I held at this dose

for 60

> days.

> T4 equivalent of 309 mcg

>

> My next scheduled dosage increase included a reduction of natural

and an

> increase of T4 and the addition of T3 (synthetics are both generics)

> My natural dose was still kept in 1/2 grain doses but was changed

to a

> total of 2.5 grain per day

> I then goofed on the cutting and sorting of the synthetics and

ended up

> with a dose of 75 mcg of T4 and 6 1/4 mcg of T3. The synthetics were

> taking first thing in the morning on an empty stomach with my dose

of

> desiccated adrenal.

> T4 equivalent of 285 mcg

>

> I noticed something was off but didn't quite know what. My pill

boxes are

> set up for 12 days at a time, it was when I was setting up pill

boxes

> after that 12 days that I'd sorted the synthetics wrong and decided

to

> jump back to my charted plan....

> Natural dose held at 2.5 grain per day, taken in half grain doses,

T4 125

> mcg, T3 25 mcg

> T4 equivalent of 335 mcg

>

> I started using the progesterone creme on May 28th. This last dose

> adjustment was begun on June 4th. To 'buffer' the jump in thyroid I

> increased my adrenal glandular by 25 %.

>

> The progesterone creme is my official wonder creme. It stopped my

24 hour

> per day sweats. I still over heated on hot days, while being active

but

> quickly cooled down. I slept deeply and restoratively and had a day

or

> two of 'wandering thoughts' *wink*

>

> On day 13 of using the creme I had a bad night sleeping. On day 14

of the

> creme I had a bad night sleeping. It was the last day to use the

creme

> until my period starts and I start counting days again. (I'm pre

> menopausal so the schedule is to start the creme that 12th day

after the

> beginning of the period and use for 14 days and then stop. Waiting

for

> the start of the period and then beginning the count again.)

>

> My first two nights without creme I slept well. Third day was high

stress

> and I had a bad night, that is not unusual for me when stressed.

Last

> night I slept very well.

>

> During this whole period since starting the creme we've had hot

weather,

> for me, and some of those days hot for others, and a lot of

humidity -

> with storms. I handled the hot humid days while on the creme better

than

> I have in over ten years.

>

> My last day on the creme was last Friday... It's now Wednesday.

Tuesday

> and today we've had a break in the weather, the temp has dropped.

It was

> in the 60s this morning, down from the 80s that we've been having

yet I

> was over heating badly. Even going out in the breeze or sitting in

front

> of the fan I was having trouble feeling comfortable. I was sweating

> profusely. I was working on my chores... some cooking, some dishes

and

> vacuuming. I was taking breaks in between because I felt too warm.

When I

> was all done and came back in here to sit down I got chilled after a

> while... my clothes were soaked with sweat and I was sitting by an

open

> window.

>

> After my clothes dried I became warm again. I'm in the sitting part

of my

> day... for the last four hours now... and still feel warm.. not

hot...

> not enough to turn on the fan... but warm.

>

> My period has not yet started. I don't get PMS, I have no warning

> symptoms.. I just watch for spotting. The last six months or so I

start

> spotting in the early morning.. which is supposed to be the time of

day

> that the body, with healthy adrenals, is supposed to start it. Over

night

> or later day starts are supposed to be signals that the body is out

of

> balance.

>

> Sunday, Monday, Tuesday and today, Wednesday I have had severe early

> morning fatigue, this has not been usual for me for, geez.. two

years?

> Unless I've been chronically short on sleep... and even then, I'm

usually

> a morning person and even short on sleep I tend to pick up after the

> second dose of natural (on my old, pre synthetic, dosing schedule)

>

> Monday and Tuesday I went and laid down for an hour to 'recharge'.

Today

> I forced myself not to and I'm dragging butt, now. I want to sleep.

It's

> 5 pm. I'm 12 hours into my normal day. I have another 5 hours

before my

> regular sleep time.... I should not be this wasted.

>

> Okay... now you have all the factors, I think....

>

> I WANT to go back to all naturals, but I need to stretch what I

have with

> the synthetic.

> I want to stay on the creme every day, but don't know if that is

exactly

> wise since I'm not yet (I don't think) in menopause and my cycles

have

> been regular and 'normal'

> I do NOT want to increases my T4 equivalent. I want that to remain

> stable, at the 335 equivalent that I'm now at, for at least 60 days

and

> then re evaluate.

>

> Keeping in mind that the 'standard' dose of T4 is said to be 1 mcg

per

> pound of body weight for FULL replacement and I'm considerably over

335

> in weight. I tend to believe that I'm still not at my optimal

dose... but

> have had noticeable improvements since beginning my increases in

> February. I still feel that there is room for improvement but I also

> realize that for as many years that I was underdosed that I may have

> permanent damage that may not be correctable, regardless of my

dose, or

> source, of hormone.

>

> So. What do the rest of you see?

> Are my fatigue symptoms related to a delayed stress thing from the

large

> jump in dosage that I made 11 days ago? (remember I have no

remaining

> thyroid function, so it's not a drop in natural production

triggered by

> the dosage adjustment)

> Is it due to stopping the progesterone creme?

> Is it because the progesterone creme did a lot to balance my

suspected

> estrogen dominance and I used up more thyroid hormone during that

time

> and now am in a slump (shortage) of available hormone?

> Is it because I really really don't convert/handle/tolerate

synthetic

> well enough for it to give my body what it needs and this shift may

have

> left me short of usable hormone?

>

> I haven't changed anything with any of my other supplements or

vitamins..

> except for opening a two new bottles which I did about 8 weeks

ago, I

> opened new bottles of adrenal Glandular and selenium. The adrenal

was the

> same brand/source that I've been using for over two years. The

selenium

> was the same formulation but from a different source than what I

used the

> year previous.

>

> I've had no extra physical exertion the last couple of months.

>

> Light bulb moment... I ran out of calcium 4 days ago and I've been

out of

> my regular vitamin C for about 2 months.... All though dropping

either of

> these shouldn't make a difference I add them anyway, cuz they may

mean

> something.

>

> Okay.. more factors, sorry...

>

> Does anyone see anything that I'm not catching... I'm at a stage

right

> now were I'm flubbergusted and just want it fixed.. you guys KNOW

what I

> mean... and I don't want to do something stupid... it's easier to

see

> something in someone else than it is yourself... that's why I'm

laying it

> all out for you guys, to see if you can see something I'm missing.

>

> I'll be setting up the pill boxes between 8 and 10 Thursday morning.

>

> Topper () *can I take a nap now???? Please???? I've been a good

> girl, I vacuumed without being asked...... *

June 15, 2005

, have you been tested for insulin and glucose? Insulin

resistance can cause weakness and fatigue. Insulin resistance can

cause obesity and obesity can cause insulin resistance. I'm so tired

after working in the heat all day, I figure I better not comment

about anything you said here until I'm rested.

Chris

> Okay, I know what I WANT to do.. and it would work.. and I know

what I

> should do, but am not sure it would work. Now that I have you all

> confused... wait until you see the res!!!!

>

> ... maybe a seat belt and crash helmet are in order. For sure grab a

> paper an pencil to take notes!!! hehehehee

>

> I have to set up pill boxes tomorrow morning... so the sooner we can

> figure this out.. the better... If we can't.. I'll keep it all the

same

> as it is right now until we come up with an idea as to what my body

is

> trying to tell me.

>

> We all know how hard it is to see yourself sometimes.. and this one

has

> been bugging me.. not knowing quite what I need to shift.

>

> Brief history part.

> RAI about 15 years ago, no thyroid function. Genetic defect, not

> autoimmune, disease or injury.

> Synthroid and it's clones prescribed by docs, maximum dose never

exceeded

> 200 mcg. Ended up needed crutches to walk, ran out of Synthetic T4

and

> money for docs, labs and meds in November '99.

> Got intermittent 'left over' pills from friends an relatives between

> spring '00 to July '02. Basals dropped to temp of 97.0 or slightly

less,

> pulse of 50 and respiration of 10 and now realize I was also

dealing with

> 'air hunger'

> Started self medicating in July '02 with OTC natural, started

> prescription grade natural in July '03.

> My body is very sensitive to adjustments and dosing. Adjustments

are best

> done at 6 to 8 weeks, some have been as long as 12. I find that I

need to

> dose throughout the day, with the final dose at bedtime. Otherwise

I have

> fatigue issues.

>

> Had labs done in Feb '05

> TSH .333 ( .35 - 5.50 ) -- I know range is wrong...

> Free T4 .9 ( .8 - 1.8 )

> Free T3 2.9 ( 2.3 - 4.2 )

>

> Based on these labs, and symptoms I determined I needed to increase.

> Basals were up: Temp 98.2 to 98.4, pulse between 72 and 78,

respiration

> at 18 to 20.

>

> Financial considerations had me choose to maintain my current dose

of

> natural (I had been on this dose since April of '04, holding at the

same

> dose until I could get a ride in for labs), 7 doses of 1/2 grain

per day,

> for a total of 3 1/2 grain per day, taken sublingually. . And use

> synthetic to do my increases. This was done to stretch the stash of

> natural that I have until I can find another source.

> T4 equivalent of 259 mcg

>

> The first increase was to add 25 mcg of T4, taken first thing in the

> morning, empty stomach, along with my first 1/2 dose of natural and

my

> dose of desiccated adrenal, taken sublingually. The rest of my daily

> thyroid schedule remained the same. I didn't notice much of a

> difference.. no 'WHAM' but I had the uncomfortableness that I get

with a

> change in dosage.

> T4 equivalent of 284 mcg

>

> I was stupid, impatient and a smart A & ^% and increased another 25

mcg of

> T4 after 12 days. This hit me a bit harder and I held at this dose

for 60

> days.

> T4 equivalent of 309 mcg

>

> My next scheduled dosage increase included a reduction of natural

and an

> increase of T4 and the addition of T3 (synthetics are both generics)

> My natural dose was still kept in 1/2 grain doses but was changed

to a

> total of 2.5 grain per day

> I then goofed on the cutting and sorting of the synthetics and

ended up

> with a dose of 75 mcg of T4 and 6 1/4 mcg of T3. The synthetics were

> taking first thing in the morning on an empty stomach with my dose

of

> desiccated adrenal.

> T4 equivalent of 285 mcg

>

> I noticed something was off but didn't quite know what. My pill

boxes are

> set up for 12 days at a time, it was when I was setting up pill

boxes

> after that 12 days that I'd sorted the synthetics wrong and decided

to

> jump back to my charted plan....

> Natural dose held at 2.5 grain per day, taken in half grain doses,

T4 125

> mcg, T3 25 mcg

> T4 equivalent of 335 mcg

>

> I started using the progesterone creme on May 28th. This last dose

> adjustment was begun on June 4th. To 'buffer' the jump in thyroid I

> increased my adrenal glandular by 25 %.

>

> The progesterone creme is my official wonder creme. It stopped my

24 hour

> per day sweats. I still over heated on hot days, while being active

but

> quickly cooled down. I slept deeply and restoratively and had a day

or

> two of 'wandering thoughts' *wink*

>

> On day 13 of using the creme I had a bad night sleeping. On day 14

of the

> creme I had a bad night sleeping. It was the last day to use the

creme

> until my period starts and I start counting days again. (I'm pre

> menopausal so the schedule is to start the creme that 12th day

after the

> beginning of the period and use for 14 days and then stop. Waiting

for

> the start of the period and then beginning the count again.)

>

> My first two nights without creme I slept well. Third day was high

stress

> and I had a bad night, that is not unusual for me when stressed.

Last

> night I slept very well.

>

> During this whole period since starting the creme we've had hot

weather,

> for me, and some of those days hot for others, and a lot of

humidity -

> with storms. I handled the hot humid days while on the creme better

than

> I have in over ten years.

>

> My last day on the creme was last Friday... It's now Wednesday.

Tuesday

> and today we've had a break in the weather, the temp has dropped.

It was

> in the 60s this morning, down from the 80s that we've been having

yet I

> was over heating badly. Even going out in the breeze or sitting in

front

> of the fan I was having trouble feeling comfortable. I was sweating

> profusely. I was working on my chores... some cooking, some dishes

and

> vacuuming. I was taking breaks in between because I felt too warm.

When I

> was all done and came back in here to sit down I got chilled after a

> while... my clothes were soaked with sweat and I was sitting by an

open

> window.

>

> After my clothes dried I became warm again. I'm in the sitting part

of my

> day... for the last four hours now... and still feel warm.. not

hot...

> not enough to turn on the fan... but warm.

>

> My period has not yet started. I don't get PMS, I have no warning

> symptoms.. I just watch for spotting. The last six months or so I

start

> spotting in the early morning.. which is supposed to be the time of

day

> that the body, with healthy adrenals, is supposed to start it. Over

night

> or later day starts are supposed to be signals that the body is out

of

> balance.

>

> Sunday, Monday, Tuesday and today, Wednesday I have had severe early

> morning fatigue, this has not been usual for me for, geez.. two

years?

> Unless I've been chronically short on sleep... and even then, I'm

usually

> a morning person and even short on sleep I tend to pick up after the

> second dose of natural (on my old, pre synthetic, dosing schedule)

>

> Monday and Tuesday I went and laid down for an hour to 'recharge'.

Today

> I forced myself not to and I'm dragging butt, now. I want to sleep.

It's

> 5 pm. I'm 12 hours into my normal day. I have another 5 hours

before my

> regular sleep time.... I should not be this wasted.

>

> Okay... now you have all the factors, I think....

>

> I WANT to go back to all naturals, but I need to stretch what I

have with

> the synthetic.

> I want to stay on the creme every day, but don't know if that is

exactly

> wise since I'm not yet (I don't think) in menopause and my cycles

have

> been regular and 'normal'

> I do NOT want to increases my T4 equivalent. I want that to remain

> stable, at the 335 equivalent that I'm now at, for at least 60 days

and

> then re evaluate.

>

> Keeping in mind that the 'standard' dose of T4 is said to be 1 mcg

per

> pound of body weight for FULL replacement and I'm considerably over

335

> in weight. I tend to believe that I'm still not at my optimal

dose... but

> have had noticeable improvements since beginning my increases in

> February. I still feel that there is room for improvement but I also

> realize that for as many years that I was underdosed that I may have

> permanent damage that may not be correctable, regardless of my

dose, or

> source, of hormone.

>

> So. What do the rest of you see?

> Are my fatigue symptoms related to a delayed stress thing from the

large

> jump in dosage that I made 11 days ago? (remember I have no

remaining

> thyroid function, so it's not a drop in natural production

triggered by

> the dosage adjustment)

> Is it due to stopping the progesterone creme?

> Is it because the progesterone creme did a lot to balance my

suspected

> estrogen dominance and I used up more thyroid hormone during that

time

> and now am in a slump (shortage) of available hormone?

> Is it because I really really don't convert/handle/tolerate

synthetic

> well enough for it to give my body what it needs and this shift may

have

> left me short of usable hormone?

>

> I haven't changed anything with any of my other supplements or

vitamins..

> except for opening a two new bottles which I did about 8 weeks

ago, I

> opened new bottles of adrenal Glandular and selenium. The adrenal

was the

> same brand/source that I've been using for over two years. The

selenium

> was the same formulation but from a different source than what I

used the

> year previous.

>

> I've had no extra physical exertion the last couple of months.

>

> Light bulb moment... I ran out of calcium 4 days ago and I've been

out of

> my regular vitamin C for about 2 months.... All though dropping

either of

> these shouldn't make a difference I add them anyway, cuz they may

mean

> something.

>

> Okay.. more factors, sorry...

>

> Does anyone see anything that I'm not catching... I'm at a stage

right

> now were I'm flubbergusted and just want it fixed.. you guys KNOW

what I

> mean... and I don't want to do something stupid... it's easier to

see

> something in someone else than it is yourself... that's why I'm

laying it

> all out for you guys, to see if you can see something I'm missing.

>

> I'll be setting up the pill boxes between 8 and 10 Thursday morning.

>

> Topper () *can I take a nap now???? Please???? I've been a good

> girl, I vacuumed without being asked...... *

June 15, 2005

, have you been tested for insulin and glucose? Insulin

resistance can cause weakness and fatigue. Insulin resistance can

cause obesity and obesity can cause insulin resistance. I'm so tired

after working in the heat all day, I figure I better not comment

about anything you said here until I'm rested.

Chris

> Okay, I know what I WANT to do.. and it would work.. and I know

what I

> should do, but am not sure it would work. Now that I have you all

> confused... wait until you see the res!!!!

>

> ... maybe a seat belt and crash helmet are in order. For sure grab a

> paper an pencil to take notes!!! hehehehee

>

> I have to set up pill boxes tomorrow morning... so the sooner we can

> figure this out.. the better... If we can't.. I'll keep it all the

same

> as it is right now until we come up with an idea as to what my body

is

> trying to tell me.

>

> We all know how hard it is to see yourself sometimes.. and this one

has

> been bugging me.. not knowing quite what I need to shift.

>

> Brief history part.

> RAI about 15 years ago, no thyroid function. Genetic defect, not

> autoimmune, disease or injury.

> Synthroid and it's clones prescribed by docs, maximum dose never

exceeded

> 200 mcg. Ended up needed crutches to walk, ran out of Synthetic T4

and

> money for docs, labs and meds in November '99.

> Got intermittent 'left over' pills from friends an relatives between

> spring '00 to July '02. Basals dropped to temp of 97.0 or slightly

less,

> pulse of 50 and respiration of 10 and now realize I was also

dealing with

> 'air hunger'

> Started self medicating in July '02 with OTC natural, started

> prescription grade natural in July '03.

> My body is very sensitive to adjustments and dosing. Adjustments

are best

> done at 6 to 8 weeks, some have been as long as 12. I find that I

need to

> dose throughout the day, with the final dose at bedtime. Otherwise

I have

> fatigue issues.

>

> Had labs done in Feb '05

> TSH .333 ( .35 - 5.50 ) -- I know range is wrong...

> Free T4 .9 ( .8 - 1.8 )

> Free T3 2.9 ( 2.3 - 4.2 )

>

> Based on these labs, and symptoms I determined I needed to increase.

> Basals were up: Temp 98.2 to 98.4, pulse between 72 and 78,

respiration

> at 18 to 20.

>

> Financial considerations had me choose to maintain my current dose

of

> natural (I had been on this dose since April of '04, holding at the

same

> dose until I could get a ride in for labs), 7 doses of 1/2 grain

per day,

> for a total of 3 1/2 grain per day, taken sublingually. . And use

> synthetic to do my increases. This was done to stretch the stash of

> natural that I have until I can find another source.

> T4 equivalent of 259 mcg

>

> The first increase was to add 25 mcg of T4, taken first thing in the

> morning, empty stomach, along with my first 1/2 dose of natural and

my

> dose of desiccated adrenal, taken sublingually. The rest of my daily

> thyroid schedule remained the same. I didn't notice much of a

> difference.. no 'WHAM' but I had the uncomfortableness that I get

with a

> change in dosage.

> T4 equivalent of 284 mcg

>

> I was stupid, impatient and a smart A & ^% and increased another 25

mcg of

> T4 after 12 days. This hit me a bit harder and I held at this dose

for 60

> days.

> T4 equivalent of 309 mcg

>

> My next scheduled dosage increase included a reduction of natural

and an

> increase of T4 and the addition of T3 (synthetics are both generics)

> My natural dose was still kept in 1/2 grain doses but was changed

to a

> total of 2.5 grain per day

> I then goofed on the cutting and sorting of the synthetics and

ended up

> with a dose of 75 mcg of T4 and 6 1/4 mcg of T3. The synthetics were

> taking first thing in the morning on an empty stomach with my dose

of

> desiccated adrenal.

> T4 equivalent of 285 mcg

>

> I noticed something was off but didn't quite know what. My pill

boxes are

> set up for 12 days at a time, it was when I was setting up pill

boxes

> after that 12 days that I'd sorted the synthetics wrong and decided

to

> jump back to my charted plan....

> Natural dose held at 2.5 grain per day, taken in half grain doses,

T4 125

> mcg, T3 25 mcg

> T4 equivalent of 335 mcg

>

> I started using the progesterone creme on May 28th. This last dose

> adjustment was begun on June 4th. To 'buffer' the jump in thyroid I

> increased my adrenal glandular by 25 %.

>

> The progesterone creme is my official wonder creme. It stopped my

24 hour

> per day sweats. I still over heated on hot days, while being active

but

> quickly cooled down. I slept deeply and restoratively and had a day

or

> two of 'wandering thoughts' *wink*

>

> On day 13 of using the creme I had a bad night sleeping. On day 14

of the

> creme I had a bad night sleeping. It was the last day to use the

creme

> until my period starts and I start counting days again. (I'm pre

> menopausal so the schedule is to start the creme that 12th day

after the

> beginning of the period and use for 14 days and then stop. Waiting

for

> the start of the period and then beginning the count again.)

>

> My first two nights without creme I slept well. Third day was high

stress

> and I had a bad night, that is not unusual for me when stressed.

Last

> night I slept very well.

>

> During this whole period since starting the creme we've had hot

weather,

> for me, and some of those days hot for others, and a lot of

humidity -

> with storms. I handled the hot humid days while on the creme better

than

> I have in over ten years.

>

> My last day on the creme was last Friday... It's now Wednesday.

Tuesday

> and today we've had a break in the weather, the temp has dropped.

It was

> in the 60s this morning, down from the 80s that we've been having

yet I

> was over heating badly. Even going out in the breeze or sitting in

front

> of the fan I was having trouble feeling comfortable. I was sweating

> profusely. I was working on my chores... some cooking, some dishes

and

> vacuuming. I was taking breaks in between because I felt too warm.

When I

> was all done and came back in here to sit down I got chilled after a

> while... my clothes were soaked with sweat and I was sitting by an

open

> window.

>

> After my clothes dried I became warm again. I'm in the sitting part

of my

> day... for the last four hours now... and still feel warm.. not

hot...

> not enough to turn on the fan... but warm.

>

> My period has not yet started. I don't get PMS, I have no warning

> symptoms.. I just watch for spotting. The last six months or so I

start

> spotting in the early morning.. which is supposed to be the time of

day

> that the body, with healthy adrenals, is supposed to start it. Over

night

> or later day starts are supposed to be signals that the body is out

of

> balance.

>

> Sunday, Monday, Tuesday and today, Wednesday I have had severe early

> morning fatigue, this has not been usual for me for, geez.. two

years?

> Unless I've been chronically short on sleep... and even then, I'm

usually

> a morning person and even short on sleep I tend to pick up after the

> second dose of natural (on my old, pre synthetic, dosing schedule)

>

> Monday and Tuesday I went and laid down for an hour to 'recharge'.

Today

> I forced myself not to and I'm dragging butt, now. I want to sleep.

It's

> 5 pm. I'm 12 hours into my normal day. I have another 5 hours

before my

> regular sleep time.... I should not be this wasted.

>

> Okay... now you have all the factors, I think....

>

> I WANT to go back to all naturals, but I need to stretch what I

have with

> the synthetic.

> I want to stay on the creme every day, but don't know if that is

exactly

> wise since I'm not yet (I don't think) in menopause and my cycles

have

> been regular and 'normal'

> I do NOT want to increases my T4 equivalent. I want that to remain

> stable, at the 335 equivalent that I'm now at, for at least 60 days

and

> then re evaluate.

>

> Keeping in mind that the 'standard' dose of T4 is said to be 1 mcg

per

> pound of body weight for FULL replacement and I'm considerably over

335

> in weight. I tend to believe that I'm still not at my optimal

dose... but

> have had noticeable improvements since beginning my increases in

> February. I still feel that there is room for improvement but I also

> realize that for as many years that I was underdosed that I may have

> permanent damage that may not be correctable, regardless of my

dose, or

> source, of hormone.

>

> So. What do the rest of you see?

> Are my fatigue symptoms related to a delayed stress thing from the

large

> jump in dosage that I made 11 days ago? (remember I have no

remaining

> thyroid function, so it's not a drop in natural production

triggered by

> the dosage adjustment)

> Is it due to stopping the progesterone creme?

> Is it because the progesterone creme did a lot to balance my

suspected

> estrogen dominance and I used up more thyroid hormone during that

time

> and now am in a slump (shortage) of available hormone?

> Is it because I really really don't convert/handle/tolerate

synthetic

> well enough for it to give my body what it needs and this shift may

have

> left me short of usable hormone?

>

> I haven't changed anything with any of my other supplements or

vitamins..

> except for opening a two new bottles which I did about 8 weeks

ago, I

> opened new bottles of adrenal Glandular and selenium. The adrenal

was the

> same brand/source that I've been using for over two years. The

selenium

> was the same formulation but from a different source than what I

used the

> year previous.

>

> I've had no extra physical exertion the last couple of months.

>

> Light bulb moment... I ran out of calcium 4 days ago and I've been

out of

> my regular vitamin C for about 2 months.... All though dropping

either of

> these shouldn't make a difference I add them anyway, cuz they may

mean

> something.

>

> Okay.. more factors, sorry...

>

> Does anyone see anything that I'm not catching... I'm at a stage

right

> now were I'm flubbergusted and just want it fixed.. you guys KNOW

what I

> mean... and I don't want to do something stupid... it's easier to

see

> something in someone else than it is yourself... that's why I'm

laying it

> all out for you guys, to see if you can see something I'm missing.

>

> I'll be setting up the pill boxes between 8 and 10 Thursday morning.

>

> Topper () *can I take a nap now???? Please???? I've been a good

> girl, I vacuumed without being asked...... *

June 15, 2005

I will be brave..( hiding in corner/watching for flying objects)

Assuming your natural is equal to Armour, Armour being 9 mcg of T3

what is your daily T3 dosage?

You have a TSH reading but not sure if that is good or bad, it could

mean that having no thyroid your body is not getting enough hormone

and is signalling for more..or it could mean nothing as you have a

genetic defect.

Your T4 is really low, with the amount of T4 you are taking I would

say huge conversion problem, and wonder if maybe you are wasting

money on T4 meds. Did you get a total T4 done to see if your body

has a conversion problem or an absorbsion problem?

Your T3 is the medication your body actually uses and it could use

some improvement.

From Merck..

Thyroxine-binding globulin (TBG) is most commonly increased in

pregnancy, by estrogen therapy or oral contraceptives, and in the

acute phase of infectious hepatitis. TBG may also be increased

genetically by an X-linked abnormality.

TBG is decreased primarily by anabolic steroids, including

testosterone, and by excess amounts of corticosteroids. TBG may also

be decreased genetically. Finally, large doses of drugs such as

phenytoin and aspirin and their derivatives displace T4 from its

binding sites on TBG,

Measurement of thyroglobulin: The thyroid is the only source of this

iodinated high molecular weight glycoprotein, which is readily

detectable in normal patients and is usually elevated in patients

with nontoxic and toxic goiter. The principle use of serum

thyroglobulin is in evaluating patients after near-total or total

thyroidectomy with or without 131I ablation for differentiated

thyroid cancer. Normal or elevated serum thyroglobulin values

indicate the presence of residual normal or malignant thyroid tissue

in patients receiving TSH suppressive doses of L-thyroxine or after

withdrawal of L-thyroxine.

You had a very high level of RAI , and being 15 yrs post RAI if you

had any Thyroid function left it has now gone.. Thyroglobulin is

produced by the Thyroid only..its use is to bind and Unbind T4 and

T3 hormones, if you have very little still circulating your system

then your adrenal supplements would supress it and your progesterone

supplement would increase it..by increasing it you have a slower

release of your hormones instead of the thyroid hormone in/out you

are getting now..a reverse T3 test of total would tell you if your

body is flushing the hormones out or if it was sotred and not

available for use.

If money was not an option I really wonder if you would do better on

having a pharmacy compound a time released T3 only medication for

you. By formulating it time released it would in a sense take the

place of the thyroglobulin that is binds your hormones until the

body signals to release it.

As far as the cream goes I am not too sure about that. Obviously

your body needs it. You felt good on it.

I have seen it dosed from anywhere from 5-10 days, alone or in

combination with Estrogen..and I have seen it used daily but not on

a 14 day cycle..

Daily is when your body is low and needs replacement..the 5-10 day

dosing is used to stimulate for ovulation..a lot of times they use

it in younger woman who are delayed in starting a cycle or for those

who skip cycles.. it could be by using it longer you messed up your

cycle and it is letting you know..or it could be that you need a

lower daily dose on a continuous basis?

June 15, 2005