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Enthesopathy Aubrey--Thanks

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Thank you

Aubrey. So is this kind of like a growing pain? Noah has it in his hips,

knees, and ankles bilaterally. When it moves to the hips it really makes him

hobble. Yesterday he was not suffering, but when the doctor probed him it made

him jump. I guess the doctor knew the spot to hit.

Will Celebrex

help? Any ideas on the Ketoprofen cream?

As always, you

are the bomb. Say hello to Caroline.

Mom of Zoe (13) My very normal (teenager normal) soccer player;

Noah (8 1/2) Indeterminate colitis, PSC, Osteopenia (1-4

lumbar vertebrae), Enthesopathy;

Aidan (4 1/2) Moderately-severe SNHL bilaterally

Recycle

Yourself

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Organ Donor

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Both of the drugs you mention are pain relievers as well as being

non-steroidal anti-inflammatories. So they will reduce the

pain/discomfort. I would imagine the topical product would be best if

he had discomfort in only one location that was close to the surface

ie, ankle, knee, etc. A hip joint is kind of deep, but it may help.

Taking an oral medication like this runs the risk of ulcers, despite it

being a COX-2 drug which supposedly has less risk of ulcers. Since

these conditions tend to last months, taking an oral drug would extend

the risk of ulcers and bleeding. Tylenol might be a good choice as

well.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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As Arne mentioned, it's unlikely to help because it's not directed at

the problem. Sulfasalazine helps inflammation of the lining of the gut,

but doesn't work in other areas. Now, it may help. But I would be very,

very surprised. It would be more likely that Asacol, a fancy form of

aspirin, which is poorly absorbed into the circulation but works

locally on the gut, may help. The small amount absorbed can reduce

inflammation in other areas. I've noticed this myself when I've had to

increase my Asacol dosage because of flares of my UC. During those

times some of my arthritis discomfort seems better. But only minimally.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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