Re: Minocycline side affects

[Guest guest]

on 7/7/01 8:44 AM, Roseanne at roseanne@... wrote:

For me personally, I care more about the many people I have talked to that are testimonies to the fact that Dr. Brown's protocol works wonders for these diseases. That means more to me than any scientist's opinion =0)

~Roseanne~

You go Roseanne! And thanks for clearing that up for us.

deano

[Guest guest]

Does it indicate any where in the article the dose of minocycline that is

given for acne? Could it be that they are using much higher doses than

200mg per day for long periods of time.

Just asking and wondering.

carol/Piney/Canada

rheumatic Minocycline side affects

> Dear Roseanne and group!

>

> In an e-mail dated 06 July 2001, I apprised you of the web page

> http://www.infotech.demon.co.uk/Mino2.htm, which lists potential negative

> side effects of prolonged use of monocycline. This page is an abridge

> version of an editorial which appeared in LUPUS: An International Journal,

> Volume 8 Number 6, 1999, pp 417-418, by Dr Neil McHugh, MB Ch.B,

> FRACP, MD. The first paragraph of that page is " Minocycline is a recent

> addition to the long list of drugs that may cause lupus or at least a

> lupus-like syndrome. The inclusion of minocycline is important given its

> frequent and often prolonged use for the treatment of acne in young

people.

> . . .the use of minocycline remains frequent and awareness of adverse

> effects together with adequate monitoring would seem prudent. "

>

> The above page page does not refer to people who already have lupus, but

> instead to young people with acne who are taking monocycline for prolonged

> periods of time. An interesting two sentences are included as a sideline:

> " In addition to its antibacterial action, minocycline has immunomodulatory

> properties and inhibits the activity of matrix metalloproteinases. It is

> not known which of these properties may explain the modest benefit for

> patients with rheumatoid arthritis. "

>

> To learn more, I did a www.google.com search for " Dr Neil McHugh " and

> found the second web page http://www.infotech.demon.co.uk/Mino.htm, which

> is slightly longer than the first. It was printed in Lupus UK News &

Views,

> Spring 2000 Number 60. Key sentences include the following:

>

> " Minocycline is an antibiotic used most commonly for the treatment of

young

> people with troublesome acne... In the U.K. there were an estimated

800,000

> prescriptions for minocycline in 1993, and 188,000 individuals were

started

> on minocycline for acne in 1995. However use dropped to about 70% of

> previous levels following a report from Leeds in 1996 of the occurrence of

> lupus and hepatitis in some individuals with acne on minocycline. About 50

> cases of lupus associated with the use of minocycline have been reported

in

> the literature, and of course there will be many times that number that go

> unreported... A common pattern of presentation of the syndrome is the

onset

> of swollen painful joints and in some cases a skin rash. Other symptoms

may

> include a fever, sore throat, flu-like symptoms, headache and

depression...

> There is no doubt that minocycline is a useful agent for treating acne

that

> can be a worrying condition especially in young people. Its use will now

be

> tempered with the knowledge that certain side effects including lupus can

> occur with prolonged use, and appropriate monitoring is required. the

> question whether the tetracycline antibiotics including minocycline as a

> group are safe studies to go by, and at least alternative antibiotics are

> generally available. "

>

> I cannot assess the significance of the above information and don't want

to

> be an alarmist. The limited quantitative information presented would

> indicate that only approximately 100 out of 50,000 users are affected, or

> 0.2%. What they could be experiencing is a Herxheimer reaction to a latent

> RA condition which has not yet produced any visible symptoms.

>

> Sincerely, Harald

>

> At 09:44 AM 07/07/2001 -0400, Roseanne wrote:

> >Hello Harald and group. This is in reply to your concern about

> >Minocycline causing autoimmune diseases. The passage you quoted was

> >specifically talking about those who have Lupus, having taken

> >Minocycline. Some Lupus patients have noticed an increase in autoimmune

> >symptoms when taking Minocycline which is why they should consider

another

> >tetracycline. Some doctors prescribe only doxycycline to Lupus patients

> >as a preventative measure...

> >~Roseanne~

>

> ++++++++++++++++++++++++++++++++++++++++++++++++++

> INCREASING SALES THROUGH IMPROVED MARKETING

> Harald Weiss, Technical Marketing Group

> 4911 Royce Road, Irvine, CA 92612, USA

> Phone: (949) 786-1403, Fax: (949) 786-1403

> http://www.tmgp.com, hw@...

> ++++++++++++++++++++++++++++++++++++++++++++++++++

>

> To unsubscribe, email: rheumatic-unsubscribeegroups

>

>

>

[Guest guest]

Bob and group,

Monocycline dosages causing lupus in the treatment of acne were 50 mg to

100 mg per day -- same as for RA. Please see

http://bmj.com/cgi/content/full/312/7024/169?view=full & pmid=8563540

Regards, Harald

At 10:15 PM 07/08/2001 -0500, Bob Zarn wrote:

>Does it indicate anywhere in the article the dose of minocycline that is

>given for acne? Could it be that they are using much higher doses than

>200mg per day for long periods of time.

>

>Just asking and wondering.

>

>carol/Piney/Canada

[Guest guest]

My doctor used Doxy for acne, my daughter has used it but in a small dose and it has worked for well for her. She is not using it anymore though because the doctor gave her a different medication not anything to do with the Doxy though it just made more sense in her situation.

My friends daughter also still uses Doxy but again it is a much lower dose. I was told that it would not cause any kinda of long term problems but maybe that is because it is the Doxy and not the Mino?

Peace,

Sherry

--- Original Message -----

From: Bob Zarn

Roseanne ; rheumatic ; Harald Weiss, Technical Marketing Group

Sent: Sunday, July 08, 2001 11:15 PM

Subject: Re: rheumatic Minocycline side affects

Does it indicate any where in the article the dose of minocycline that isgiven for acne? Could it be that they are using much higher doses than200mg per day for long periods of time.Just asking and wondering.carol/Piney/Canada rheumatic Minocycline side affects> Dear Roseanne and group!>> In an e-mail dated 06 July 2001, I apprised you of the web page> http://www.infotech.demon.co.uk/Mino2.htm, which lists potential negative> side effects of prolonged use of monocycline. This page is an abridge> version of an editorial which appeared in LUPUS: An International Journal,> Volume 8 Number 6, 1999, pp 417-418, by Dr Neil McHugh, MB Ch.B,> FRACP, MD. The first paragraph of that page is "Minocycline is a recent> addition to the long list of drugs that may cause lupus or at least a> lupus-like syndrome. The inclusion of minocycline is important given its> frequent and often prolonged use for the treatment of acne in youngpeople.> . . .the use of minocycline remains frequent and awareness of adverse> effects together with adequate monitoring would seem prudent.">> The above page page does not refer to people who already have lupus, but> instead to young people with acne who are taking monocycline for prolonged> periods of time. An interesting two sentences are included as a sideline:> "In addition to its antibacterial action, minocycline has immunomodulatory> properties and inhibits the activity of matrix metalloproteinases. It is> not known which of these properties may explain the modest benefit for> patients with rheumatoid arthritis.">> To learn more, I did a www.google.com search for "Dr Neil McHugh" and> found the second web page http://www.infotech.demon.co.uk/Mino.htm, which> is slightly longer than the first. It was printed in Lupus UK News & Views,> Spring 2000 Number 60. Key sentences include the following:>> "Minocycline is an antibiotic used most commonly for the treatment ofyoung> people with troublesome acne... In the U.K. there were an estimated800,000> prescriptions for minocycline in 1993, and 188,000 individuals werestarted> on minocycline for acne in 1995. However use dropped to about 70% of> previous levels following a report from Leeds in 1996 of the occurrence of> lupus and hepatitis in some individuals with acne on minocycline. About 50> cases of lupus associated with the use of minocycline have been reportedin> the literature, and of course there will be many times that number that go> unreported... A common pattern of presentation of the syndrome is theonset> of swollen painful joints and in some cases a skin rash. Other symptomsmay> include a fever, sore throat, flu-like symptoms, headache anddepression...> There is no doubt that minocycline is a useful agent for treating acnethat> can be a worrying condition especially in young people. Its use will nowbe> tempered with the knowledge that certain side effects including lupus can> occur with prolonged use, and appropriate monitoring is required. the> question whether the tetracycline antibiotics including minocycline as a> group are safe studies to go by, and at least alternative antibiotics are> generally available.">> I cannot assess the significance of the above information and don't wantto> be an alarmist. The limited quantitative information presented would> indicate that only approximately 100 out of 50,000 users are affected, or> 0.2%. What they could be experiencing is a Herxheimer reaction to a latent> RA condition which has not yet produced any visible symptoms.>> Sincerely, Harald>> At 09:44 AM 07/07/2001 -0400, Roseanne wrote:> >Hello Harald and group. This is in reply to your concern about> >Minocycline causing autoimmune diseases. The passage you quoted was> >specifically talking about those who have Lupus, having taken> >Minocycline. Some Lupus patients have noticed an increase in autoimmune> >symptoms when taking Minocycline which is why they should consideranother> >tetracycline. Some doctors prescribe only doxycycline to Lupus patients> >as a preventative measure...> >~Roseanne~>> ++++++++++++++++++++++++++++++++++++++++++++++++++> INCREASING SALES THROUGH IMPROVED MARKETING> Harald Weiss, Technical Marketing Group> 4911 Royce Road, Irvine, CA 92612, USA> Phone: (949) 786-1403, Fax: (949) 786-1403> http://www.tmgp.com, hw@...> ++++++++++++++++++++++++++++++++++++++++++++++++++>> To unsubscribe, email: rheumatic-unsubscribeegroups>>>

[Guest guest]

I could be wrong, but from what I've read, the lupus-like symptoms are from

mino and are not seen in doxy. I know of a few people who have responded

great to doxy. It may just depend on the mycoplasm tests done up front as to

which is best for each individual.

deano

From: " Sherry " <tifkas@...>

Date: Mon, 9 Jul 2001 15:52:01 -0400

<rheumatic >

Subject: Re: rheumatic Minocycline side affects

My doctor used Doxy for acne, my daughter has used it but in a small dose

and it has worked for well for her. She is not using it anymore though

because the doctor gave her a different medication not anything to do with

the Doxy though it just made more sense in her situation.

My friends daughter also still uses Doxy but again it is a much lower dose.

I was told that it would not cause any kinda of long term problems but maybe

that is because it is the Doxy and not the Mino?

Peace,

Sherry

[Guest guest]

sherry, in my opinion, if you have every had a tick-bit or live in tick endemic area, (or people in your church, as you have mentioned) have lyme, then I would treat your daughters acne with doxy. Remember Lyme is far more infectious than most doctors (99%) know. In fact, irrespective of the Lyme, I would treat her with doxy because many of these autoimmune disorders have unknow infectious cause that might brew for years and years and may be transmissible to family members. using the doxy may help with the acne but it might also suppress some nasty infections. for what its worth (fwiw) kathy

Re: rheumatic Minocycline side affects

Does it indicate any where in the article the dose of minocycline that isgiven for acne? Could it be that they are using much higher doses than200mg per day for long periods of time.Just asking and wondering.carol/Piney/Canada rheumatic Minocycline side affects> Dear Roseanne and group!>> In an e-mail dated 06 July 2001, I apprised you of the web page> http://www.infotech.demon.co.uk/Mino2.htm, which lists potential negative> side effects of prolonged use of monocycline. This page is an abridge> version of an editorial which appeared in LUPUS: An International Journal,> Volume 8 Number 6, 1999, pp 417-418, by Dr Neil McHugh, MB Ch.B,> FRACP, MD. The first paragraph of that page is " Minocycline is a recent> addition to the long list of drugs that may cause lupus or at least a> lupus-like syndrome. The inclusion of minocycline is important given its> frequent and often prolonged use for the treatment of acne in youngpeople.> . . .the use of minocycline remains frequent and awareness of adverse> effects together with adequate monitoring would seem prudent. " >> The above page page does not refer to people who already have lupus, but> instead to young people with acne who are taking monocycline for prolonged> periods of time. An interesting two sentences are included as a sideline:> " In addition to its antibacterial action, minocycline has immunomodulatory> properties and inhibits the activity of matrix metalloproteinases. It is> not known which of these properties may explain the modest benefit for> patients with rheumatoid arthritis. " >> To learn more, I did a www.google.com search for " Dr Neil McHugh " and> found the second web page http://www.infotech.demon.co.uk/Mino.htm, which> is slightly longer than the first. It was printed in Lupus UK News & Views,> Spring 2000 Number 60. Key sentences include the following:>> " Minocycline is an antibiotic used most commonly for the treatment ofyoung> people with troublesome acne... In the U.K. there were an estimated800,000> prescriptions for minocycline in 1993, and 188,000 individuals werestarted> on minocycline for acne in 1995. However use dropped to about 70% of> previous levels following a report from Leeds in 1996 of the occurrence of> lupus and hepatitis in some individuals with acne on minocycline. About 50> cases of lupus associated with the use of minocycline have been reportedin> the literature, and of course there will be many times that number that go> unreported... A common pattern of presentation of the syndrome is theonset> of swollen painful joints and in some cases a skin rash. Other symptomsmay> include a fever, sore throat, flu-like symptoms, headache anddepression...> There is no doubt that minocycline is a useful agent for treating acnethat> can be a worrying condition especially in young people. Its use will nowbe> tempered with the knowledge that certain side effects including lupus can> occur with prolonged use, and appropriate monitoring is required. the> question whether the tetracycline antibiotics including minocycline as a> group are safe studies to go by, and at least alternative antibiotics are> generally available. " >> I cannot assess the significance of the above information and don't wantto> be an alarmist. The limited quantitative information presented would> indicate that only approximately 100 out of 50,000 users are affected, or> 0.2%. What they could be experiencing is a Herxheimer reaction to a latent> RA condition which has not yet produced any visible symptoms.>> Sincerely, Harald>> At 09:44 AM 07/07/2001 -0400, Roseanne wrote:> >Hello Harald and group. This is in reply to your concern about> >Minocycline causing autoimmune diseases. The passage you quoted was> >specifically talking about those who have Lupus, having taken> >Minocycline. Some Lupus patients have noticed an increase in autoimmune> >symptoms when taking Minocycline which is why they should consideranother> >tetracycline. Some doctors prescribe only doxycycline to Lupus patients> >as a preventative measure...> >~Roseanne~>> ++++++++++++++++++++++++++++++++++++++++++++++++++> INCREASING SALES THROUGH IMPROVED MARKETING> Harald Weiss, Technical Marketing Group> 4911 Royce Road, Irvine, CA 92612, USA> Phone: (949) 786-1403, Fax: (949) 786-1403> http://www.tmgp.com, hw@...> ++++++++++++++++++++++++++++++++++++++++++++++++++>> To unsubscribe, email: rheumatic-unsubscribeegroups>>>