Re: Genetics/Heredity

[Guest guest]

,

I'm so sorry to hear that your brother is also having problems. It is so

frustrating isn't it? I hope that he can find some way to deal with this

terrible news.

Because I have been affected by DES, hypospadius in any sons I might have is a

concern for me. A study was done that noted a far higher incidence of

hypospadius in DES grandsons than in the general population. The link is below:

http://www.cdc.gov/DES/consumers/research/recent_hypospadias.html

Yes, DES can cause BU, SU and a whole range of other MAs besides the notorious

t-shaped uterus (which I have). They are still doing studies on the effects of

grandchildren of those who took DES. It is possible that if your grandmother

had complications during pregnancy (such as bleeding or multiple miscarriages)

that she was given DES. It was given in pill form, by injection, and in

prenatal vitamins.

I'm so sorry that you are having to deal with so much heartache in your family.

I hope you can find the answers to your questions.

Mikell, 32

t-shaped due to DES

1 m/c

ttc #1 17 months

I'm waiting to hear

from my grandmother whether or not she took DES while pregnant, but

is DES linked to BU or SU, and in grandchildren? Thanks for any

answers you all might have. I respect your opinions.

, 24, BU/SU?, 1 m/c

[Guest guest]

,

I have been wondering about the genetics aspect of all of

this also. My brother has one testical, one kidney, and

is sterile also. Wondering how it all fits in?

UU, TTC

[Guest guest]

I agree with the gentics idea. My sister had PCOS. I don't know if she had

any other problems, she recently died without children. I also have an aunt

who had 1 fallopian tube. Go figure- LIz

>

>Reply-To: MullerianAnomalies

>To: MullerianAnomalies

>Subject: Re: Genetics/Heredity

>Date: Mon, 26 Jul 2004 09:08:51 -0400

>

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[Guest guest]

Hey .

I don't know a ton about DES or the genetics of MAs, but I do know

that my grandmother took DES while she was pregnant, my mom had an

ectopic pregnancy, and I am UD. Seems a little too coincidental to

me.

> Hey all,

> I just found out some sad news. My brother (27) just found out he

is

> infertile (they don't think he is producing sperm). When he was

like

> five, he had surgery for hypospadius. His doctor told him that

> hypospadius was not the reason he is infertile. Does anyone know

> more on this? I have been reading on some websites and some say

that

> hypospadius can be a cause of infertility. Could his problems be

> similar/related to mine (BU/SU)? Also, I just found out that my

> paternal grandmother had a tipped uterus. What is a tipped

uterus?

> She said her doctor said he was suprised she was even able to get

> pregnant. And then, on my mother's side, my grandpa has a pelvic

> kidney (which I also have). Also, on my father's side there is a

> history of Stickler's syndrome. Anyone know anything about it?

From

> what I read, it could be a cause of hypospadius. I just wonder how

> far all of this stuff can go back, and I feel destined to pass on

> these sucky traits to my children. My twin sister already found

out

> her soon to be born son has a pelvic kidney. I'm waiting to hear

> from my grandmother whether or not she took DES while pregnant, but

> is DES linked to BU or SU, and in grandchildren? Thanks for any

> answers you all might have. I respect your opinions.

>

> , 24, BU/SU?, 1 m/c