Re: Tegafur-Uracil, or Uftoral, also called UFT

[Guest guest]

Thanks,Ed!!

I,too was wondering what UFT is.

>

> UFT (Uftoral)

>

> How is it given?

> Uftoral is taken as white capsules three times a day at regular

> intervals. It is usually taken for four weeks, followed by a seven

> day break. The cycle is then repeated.

>

> A tablet called calcium leucovorin (folinic acid) is given with

> Uftoral. This is thought to increase its effectiveness.

> How it works: Uftoral is a combination of two chemotherapy drugs:

> tegafur and uracil. When the capsules are taken, the tegafur is

taken

> up by the cancer cells and slowly develops into what is known as

the

> active drug 5 fluorouracil (5FU). The uracil interacts with the

> tegafur and stops the breakdown of 5FU. This means that there is a

> higher concentration of 5FU in the tumour cells than when tegafur

is

> given alone, or when the same dose of 5FU is given into a vein. 5FU

> itself has been used as a drug treatment for bowel cancer for

almost

> 50 years.

[Guest guest]

Thanks,Ed!!

I,too was wondering what UFT is.

>

> UFT (Uftoral)

>

> How is it given?

> Uftoral is taken as white capsules three times a day at regular

> intervals. It is usually taken for four weeks, followed by a seven

> day break. The cycle is then repeated.

>

> A tablet called calcium leucovorin (folinic acid) is given with

> Uftoral. This is thought to increase its effectiveness.

> How it works: Uftoral is a combination of two chemotherapy drugs:

> tegafur and uracil. When the capsules are taken, the tegafur is

taken

> up by the cancer cells and slowly develops into what is known as

the

> active drug 5 fluorouracil (5FU). The uracil interacts with the

> tegafur and stops the breakdown of 5FU. This means that there is a

> higher concentration of 5FU in the tumour cells than when tegafur

is

> given alone, or when the same dose of 5FU is given into a vein. 5FU

> itself has been used as a drug treatment for bowel cancer for

almost

> 50 years.

[Guest guest]

..

> It this just a UK treatment, or its it avaiable here in the states

as well ?

> a

I first heard of UFT from Priscilla Savary's message #10388, where

she says " I believe you also have UFT which in the States we will

never have (not for good reasons) "

Then I looked it up on a search engine and pasted in the snippet

in my post. Sounds like it might compete with Xeloda, I dunno.

Best

Ed

[Guest guest]

THANK YOU