Re: Questions- Just Wondering

[Guest guest]

No both were with 5FU Leucovorin.

" As long as I know the WHO

I can bear any HOW

even though I don't know WHY "

(Commentary on Job from Dialogue in Despair)

[Guest guest]

Naurice,

I've done both but never together nor alone. I had nausea and

other stuff (but not hives) when I did oxaliplatin (including the

neuropathy thing) and I had nausea and other stuff (but not hives),

not as bad, but mixed with some high blood pressure and hand and

foot syndrome when I was on Irinotecan and Avastin. Both times were

with 5FU and Leucovorin.

I think the 5FU is signficant - in many side effects perhaps the

most signficant. When you say " alone " , do you really mean " alone "

or was the oxaliplatin with 5FU - if so, there is a really good

possibility that those side effects were due either to the 5FU or to

the dynamic of mixing them with 5FU. In fact, Avastin has a very

slight side effect trail by itself; Oxaliplatin is hard to judge,

because studies that I'm familiar with where it was used by itself

were terminated early because another arm (namely one where it was

mixed with 5FU) were so much more successful that the alone arm was

terminated too early to glean much information.

Joe

> Those of you who have been on both Oxilaplatin and Avastin did you

have

> adverse reactions to the Oxilaplatin? Phil's been off Oxilaplatin

for about 4-5

> months now but I am wondering if this was just Phil's experience

or if

> Oxilaplatin and Avastin might simply be a bad mix for everyone.

>

> Phil didn't have the reactions (severe nausea, pain, hives) when

he was on

> Oxilaplatin alone and doesn't have them now with Avastin alone.

>

> Just wondering what your experience has been.

> Narice

>

>

>

>

[Guest guest]

Narice, I think you already know my answer to this one but just in

case, Bert was on 5fu/leuc/oxal and in all honesty, the only side

effects he experienced were very dry skin, watery/tearing eyes, and

doable neuropathy for a couple of days following each treatment to

hands and feet. He's been off chemo now since July 2003 and so far,

so good with everything.

Hugs,

Monika

> Those of you who have been on both Oxilaplatin and Avastin did you

have

> adverse reactions to the Oxilaplatin? Phil's been off Oxilaplatin

for about 4-5

> months now but I am wondering if this was just Phil's experience or

if

> Oxilaplatin and Avastin might simply be a bad mix for everyone.

>

> Phil didn't have the reactions (severe nausea, pain, hives) when he

was on

> Oxilaplatin alone and doesn't have them now with Avastin alone.

>

> Just wondering what your experience has been.

> Narice

>

>

>

>

[Guest guest]

Hello Narice,

I am on the mix of Oxaliplatin and Xeloda and have neuropathy (sensitivity to

cold - even have gloves for the refrig; and bad nausea. I am off it now for six

weeks, the ox not the xel, and then back on the ox for tow or three rounds, then

I go for reverse surgery. The nausea was bad; my doc came me special meds for

it Emend (I am told they are $300 a pill. ) You take three at for one a day at

the beginning of the week. It works pretty well.

Stay well.

Karima

" Do all you have

with what you have

in the time you have "

in the place you are. "

Anonymous

Questions- Just Wondering

Those of you who have been on both Oxilaplatin and Avastin did you have

adverse reactions to the Oxilaplatin? Phil's been off Oxilaplatin for about

4-5

months now but I am wondering if this was just Phil's experience or if

Oxilaplatin and Avastin might simply be a bad mix for everyone.

Phil didn't have the reactions (severe nausea, pain, hives) when he was on

Oxilaplatin alone and doesn't have them now with Avastin alone.

Just wondering what your experience has been.

Narice