RE: Odd results

[Guest guest]

Thanks for the update Shara.

I will pray for you next Tuesday and I hope the biopsy gives you some

answers.

[Guest guest]

Shara, Best of luck on your biopsy. I'm really glad they are going to do it

sooner rather than later. I know I was truely a worry wort before mine. I

procrastinated for over a year, It wasn't the anticipation of pain that bothered

me (cause I have an incredibly high pain threshold), it's just the " not knowing "

that is so hard. It really didn't bother me at all, I had no premedication, and

borrowed my son's MC2 (?) player, just listened to music and asked Dr. H if I

could just block him and the rest of his crew out.... He laughed wholeheartedly

and said " Sure, just so you can hear me when I ask you to take the deep breaths "

I listened to the best of jazz, and all was over before I knew it. Anyway, best

of luck. It will feel really good to have an answer regarding your renal

function. Bonnie

sl_piercetx wrote:I saw my doctor today at the clinic. He

said that the Creatinine

clearance of 189 indicated that my kidneys are going through

hyperfiltration. He said this is a common thing in pregnant women

and diabetics and can cause kidney burn out. As far as I know I'm

not pregnant or shouldn't be. I'm going to take a test just in case,

but it's not likely. What is strange is that they seemed to have

never slowed down after I had my son. He said my results are not

evident of IgA, but he really has no idea what is going on...So, I

asked him when I might be able to have the biopsy done and he

said " how about next Tuesday. " So that's when I am tenatively

scheduled for it. It's always a strange thing to have the doctor

say...umm yeah this is weird I don't know what's going on. - Shara

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Visit our companion website at www.igan.ca. The site is entirely supported by

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Thank you

[Guest guest]

Don't worry, there's nothing to it, really. And then you will know exactly

what's going on in those kidneys.

Hyperfiltration is what the kidneys do when they start losing kidney function.

It just means that the good nephrons take on more work to compensate for the bad

ones. It restores some degree of kidney function, but in the long run, it wears

out the remaining nephrons faster. Hyperfiltration is why sometimes significant

loss of kidney function is not immediately apparent and can go completely

unnoticed.

Good luck. You're lucky to get in to have it done so fast. When mine was

ordered, it was a number of months before I actually had it, and another 6 weeks

after that for the results.

Pierre

Odd results

I saw my doctor today at the clinic. He said that the Creatinine

clearance of 189 indicated that my kidneys are going through

hyperfiltration. He said this is a common thing in pregnant women

and diabetics and can cause kidney burn out. As far as I know I'm

not pregnant or shouldn't be. I'm going to take a test just in case,

but it's not likely. What is strange is that they seemed to have

never slowed down after I had my son. He said my results are not

evident of IgA, but he really has no idea what is going on...So, I

asked him when I might be able to have the biopsy done and he

said " how about next Tuesday. " So that's when I am tenatively

scheduled for it. It's always a strange thing to have the doctor

say...umm yeah this is weird I don't know what's going on. - Shara

[Guest guest]

Thanks for the comforting words. Dr. Hamner assured me that mine

would be quick and relatively painless. I had expected at least a

month wait to get it done, but I think he is concerned that someone

my age is having these kinds of problems already. I am very happy I

have a proactive doctor instead of one that says, see you in 6 months

for a check up. My son's first day of school is not exactly the day I

wanted to have it done on, but I'll take it especially since he's

working it out for me.

thank you for your prayers. I've been doing a lot of that

myself. Bonnie thank you as well. One more question...Dr. Hamner said

that the biopsy would be an overnight stay and that he would not let

me get out of bed until the next morning. He said he is over cautious

but I thought that was a normal procedure with kidney biopsies. Did

any of you get out of the hospital the same day and did you have any

pain in the days after? - Shara

> Don't worry, there's nothing to it, really. And then you will know

exactly what's going on in those kidneys.

>

> Hyperfiltration is what the kidneys do when they start losing

kidney function. It just means that the good nephrons take on more

work to compensate for the bad ones. It restores some degree of

kidney function, but in the long run, it wears out the remaining

nephrons faster. Hyperfiltration is why sometimes significant loss of

kidney function is not immediately apparent and can go completely

unnoticed.

>

> Good luck. You're lucky to get in to have it done so fast. When

mine was ordered, it was a number of months before I actually had it,

and another 6 weeks after that for the results.

>

> Pierre

> Odd results

>

>

> I saw my doctor today at the clinic. He said that the Creatinine

> clearance of 189 indicated that my kidneys are going through

> hyperfiltration. He said this is a common thing in pregnant women

> and diabetics and can cause kidney burn out. As far as I know I'm

> not pregnant or shouldn't be. I'm going to take a test just in

case,

> but it's not likely. What is strange is that they seemed to have

> never slowed down after I had my son. He said my results are not

> evident of IgA, but he really has no idea what is going on...So,

I

> asked him when I might be able to have the biopsy done and he

> said " how about next Tuesday. " So that's when I am tenatively

> scheduled for it. It's always a strange thing to have the doctor

> say...umm yeah this is weird I don't know what's going on. - Shara

>

>

>

>

>

>

>

[Guest guest]

A kidney biopsy is a day procedure for most people. When I had mine, in 1993, I

had an overnight stay in the hospital. Back then, they thought it was important

to monitor vitals, check for bleeding, etc.

Pierre

Re: Odd results

Thanks for the comforting words. Dr. Hamner assured me that mine

would be quick and relatively painless. I had expected at least a

month wait to get it done, but I think he is concerned that someone

my age is having these kinds of problems already. I am very happy I

have a proactive doctor instead of one that says, see you in 6 months

for a check up. My son's first day of school is not exactly the day I

wanted to have it done on, but I'll take it especially since he's

working it out for me.

thank you for your prayers. I've been doing a lot of that

myself. Bonnie thank you as well. One more question...Dr. Hamner said

that the biopsy would be an overnight stay and that he would not let

me get out of bed until the next morning. He said he is over cautious

but I thought that was a normal procedure with kidney biopsies. Did

any of you get out of the hospital the same day and did you have any

pain in the days after? - Shara

[Guest guest]

Shara, I had my biopsy and was released about 8 hours later...after a

lot of observation. I also experienced a complication with a small

bleed or bruise on the kidney during the biopsy. Then I experienced

some very strange sharp pains in my left side, when I tried to move for

the next couple of days. They believe it was due to the bruising as it

was very deep. The observations were basically BP, pulse etc...urine

colour, just to make sure everything was ok.

Good luck with your biopsy, I am sure it will be fine. Having mine was

very frustrating initially, but somewhat of a relief once they had the

results and could confirm the diagnosis. Now I just need to figure out

what I need to do from here. I see my neph on the 13th and believe me I

am really anxious to sit with her and ask a ton of questions.

S - Vancouver, BC Canada

________________________________

From: sl_piercetx

Sent: Wednesday, September 01, 2004 6:38 AM

To: iga-nephropathy

Subject: Re: Odd results

Thanks for the comforting words. Dr. Hamner assured me that mine

would be quick and relatively painless. I had expected at least a

month wait to get it done, but I think he is concerned that someone

my age is having these kinds of problems already. I am very happy I

have a proactive doctor instead of one that says, see you in 6 months

for a check up. My son's first day of school is not exactly the day I

wanted to have it done on, but I'll take it especially since he's

working it out for me.

thank you for your prayers. I've been doing a lot of that

myself. Bonnie thank you as well. One more question...Dr. Hamner said

that the biopsy would be an overnight stay and that he would not let

me get out of bed until the next morning. He said he is over cautious

but I thought that was a normal procedure with kidney biopsies. Did

any of you get out of the hospital the same day and did you have any

pain in the days after? - Shara

> Don't worry, there's nothing to it, really. And then you will know

exactly what's going on in those kidneys.

>

> Hyperfiltration is what the kidneys do when they start losing

kidney function. It just means that the good nephrons take on more

work to compensate for the bad ones. It restores some degree of

kidney function, but in the long run, it wears out the remaining

nephrons faster. Hyperfiltration is why sometimes significant loss of

kidney function is not immediately apparent and can go completely

unnoticed.

>

> Good luck. You're lucky to get in to have it done so fast. When

mine was ordered, it was a number of months before I actually had it,

and another 6 weeks after that for the results.

>

> Pierre

> Odd results

>

>

> I saw my doctor today at the clinic. He said that the Creatinine

> clearance of 189 indicated that my kidneys are going through

> hyperfiltration. He said this is a common thing in pregnant women

> and diabetics and can cause kidney burn out. As far as I know I'm

> not pregnant or shouldn't be. I'm going to take a test just in

case,

> but it's not likely. What is strange is that they seemed to have

> never slowed down after I had my son. He said my results are not

> evident of IgA, but he really has no idea what is going on...So,

I

> asked him when I might be able to have the biopsy done and he

> said " how about next Tuesday. " So that's when I am tenatively

> scheduled for it. It's always a strange thing to have the doctor

> say...umm yeah this is weird I don't know what's going on. - Shara

>

>

>

>

>

>

>

[Guest guest]

Hi Shara,

I had to stay overnight with both my kidney biopsies. On the first one, I had

to stay in bed until the next morning, but on the second one, I begged them

to let me use the restroom and my Neph conceded after a couple of hours.

I had a very mild discomfort for a few days afterwards, but nothing bad at

all. I think I took Tylenol a couple of times, but that was it.

It won't be bad. I am just sorry you will have to miss the first day of your

son's school, but at least you will get it over with pretty quickly.

In a message dated 9/1/2004 7:17:03 AM Pacific Daylight Time,

sharareece@... writes:

> One more question...Dr. Hamner said

> that the biopsy would be an overnight stay and that he would not let

> me get out of bed until the next morning. He said he is over cautious

> but I thought that was a normal procedure with kidney biopsies. Did

> any of you get out of the hospital the same day and did you have any

> pain in the days after? - Shara

>

[Guest guest]

Shara, My biopsy was in March and I had to stay overnight. Also had

to stay absolute prone for 6 hours with no bathroom privileges to

avoid clots. I had no after effects nor pain. Everything went

smoothly with the team.

Good Luck! Gloria

> > Don't worry, there's nothing to it, really. And then you will

know

> exactly what's going on in those kidneys.

> >

> > Hyperfiltration is what the kidneys do when they start losing

> kidney function. It just means that the good nephrons take on more

> work to compensate for the bad ones. It restores some degree of

> kidney function, but in the long run, it wears out the remaining

> nephrons faster. Hyperfiltration is why sometimes significant loss

of

> kidney function is not immediately apparent and can go completely

> unnoticed.

> >

> > Good luck. You're lucky to get in to have it done so fast. When

> mine was ordered, it was a number of months before I actually had

it,

> and another 6 weeks after that for the results.

> >

> > Pierre

> > Odd results

> >

> >

> > I saw my doctor today at the clinic. He said that the

Creatinine

> > clearance of 189 indicated that my kidneys are going through

> > hyperfiltration. He said this is a common thing in pregnant

women

> > and diabetics and can cause kidney burn out. As far as I know

I'm

> > not pregnant or shouldn't be. I'm going to take a test just in

> case,

> > but it's not likely. What is strange is that they seemed to

have

> > never slowed down after I had my son. He said my results are

not

> > evident of IgA, but he really has no idea what is going

on...So,

> I

> > asked him when I might be able to have the biopsy done and he

> > said " how about next Tuesday. " So that's when I am tenatively

> > scheduled for it. It's always a strange thing to have the

doctor

> > say...umm yeah this is weird I don't know what's going on. -

Shara

> >

> >

> >

> >

> >

> >

> >

[Guest guest]

Shara,

I was in overnight too. My b/p was still not controlled well at the time so

that was the " reason " I was kept overnight. The other more important one is my

neph didn't believe I would lay in bed for the 24 hours since I homeschool my

two kids.....so he kept me overnight. ) I still thank him for that. I had

some mild pain in the days following. What you have to remember is even though

you might be feeling fine you must follow the no heavy lifting restrictions for

as long as your neph tells you to. After all you are having a thing stuck thru

muscle tissue and into a major organ in your body....it needs time to heal even

if it doesn't feel sore. I also had some residual tightness in the area of my

biopsy for about 6 months afterwards. If I turned a certain way it felt like

things were pulling " funny " inside. Exercise and stretching helped to alleviate

that.

Good luck with yours!

Amy

Re: Odd results

Thanks for the comforting words. Dr. Hamner assured me that mine

would be quick and relatively painless. I had expected at least a

month wait to get it done, but I think he is concerned that someone

my age is having these kinds of problems already. I am very happy I

have a proactive doctor instead of one that says, see you in 6 months

for a check up. My son's first day of school is not exactly the day I

wanted to have it done on, but I'll take it especially since he's

working it out for me.

thank you for your prayers. I've been doing a lot of that

myself. Bonnie thank you as well. One more question...Dr. Hamner said

that the biopsy would be an overnight stay and that he would not let

me get out of bed until the next morning. He said he is over cautious

but I thought that was a normal procedure with kidney biopsies. Did

any of you get out of the hospital the same day and did you have any

pain in the days after? - Shara

[Guest guest]

Shara,

Mine was a quickie. I was in and out within a few hours. It didn't hurt.

The only complication was when I bled all over the hospital bed. They hadn'

t applied pressure to the right spot!

The regular radiologist was out and I felt like I was the first kidney

biopsy the other radiologist had ever done. The technician kept telling him

how to do it. I think he had out an instruction manual too!

IgA was a positive diagnosis for me. My mistaken Neph at the time kept

saying it was diabetic kidney disease. I am grateful to have IgA, the

alternative was much worse!

Good Luck! I shall send positive vibes from Austin!

Cyndi

Re: Odd results

Shara,

I was in overnight too. My b/p was still not controlled well at the

time so that was the " reason " I was kept overnight. The other more

important one is my neph didn't believe I would lay in bed for the 24 hours

since I homeschool my two kids.....so he kept me overnight. ) I still

thank him for that. I had some mild pain in the days following. What you

have to remember is even though you might be feeling fine you must follow

the no heavy lifting restrictions for as long as your neph tells you to.

After all you are having a thing stuck thru muscle tissue and into a major

organ in your body....it needs time to heal even if it doesn't feel sore. I

also had some residual tightness in the area of my biopsy for about 6 months

afterwards. If I turned a certain way it felt like things were pulling

" funny " inside. Exercise and stretching helped to alleviate that.

Good luck with yours!

Amy

Re: Odd results

Thanks for the comforting words. Dr. Hamner assured me that mine

would be quick and relatively painless. I had expected at least a

month wait to get it done, but I think he is concerned that someone

my age is having these kinds of problems already. I am very happy I

have a proactive doctor instead of one that says, see you in 6 months

for a check up. My son's first day of school is not exactly the day I

wanted to have it done on, but I'll take it especially since he's

working it out for me.

thank you for your prayers. I've been doing a lot of that

myself. Bonnie thank you as well. One more question...Dr. Hamner said

that the biopsy would be an overnight stay and that he would not let

me get out of bed until the next morning. He said he is over cautious

but I thought that was a normal procedure with kidney biopsies. Did

any of you get out of the hospital the same day and did you have any

pain in the days after? - Shara

[Guest guest]

When I had my biopsy, the radiologist had a new pistol-style biopsy needle. He

said I was the first patient he actually used it on, but not to worry, he had

been practising on fruit all week

Pierre

RE: Odd results

Shara,

Mine was a quickie. I was in and out within a few hours. It didn't hurt.

The only complication was when I bled all over the hospital bed. They hadn'

t applied pressure to the right spot!

The regular radiologist was out and I felt like I was the first kidney

biopsy the other radiologist had ever done. The technician kept telling him

how to do it. I think he had out an instruction manual too!

IgA was a positive diagnosis for me. My mistaken Neph at the time kept

saying it was diabetic kidney disease. I am grateful to have IgA, the

alternative was much worse!

Good Luck! I shall send positive vibes from Austin!

Cyndi

[Guest guest]

Shara,

With my biopsy, most of my fears came from the use of needles, since they freak

me

out so. I was in the hospital over night and confined to bed for the first 8 or

10 hours,

I can't recall. When I insisted on getting out of bed to use the bathroom around

2 am

(girls and bed pans don't mix well) I passed out and was promptly told to stay

in bed

till release.

Depending on how fast I got up or out of bed, I did have some pain for about two

weeks after. It's important to remember not everyone respond to an injury or

even to

pain the same way. I wish you luck. Getting it done and getting to a diagnosis

is

important in moving forward.

BTW, I found it helpful to practice holding my breath to the same level for

brief

periods the night before biopsy.

peace,

[Guest guest]

Wow, thank you for all of the responses. I've got to remember:

practice holding breath, no lifting, pee before arrival and limit

fluids so I wont have to later. Thank you for the great advice. I'll

let you all know how it goes. - Shara

> Shara,

> With my biopsy, most of my fears came from the use of needles,

since they freak me

> out so. I was in the hospital over night and confined to bed for

the first 8 or 10 hours,

> I can't recall. When I insisted on getting out of bed to use the

bathroom around 2 am

> (girls and bed pans don't mix well) I passed out and was promptly

told to stay in bed

> till release.

>

> Depending on how fast I got up or out of bed, I did have some pain

for about two

> weeks after. It's important to remember not everyone respond to an

injury or even to

> pain the same way. I wish you luck. Getting it done and getting to

a diagnosis is

> important in moving forward.

>

> BTW, I found it helpful to practice holding my breath to the same

level for brief

> periods the night before biopsy.

>

> peace,

>

[Guest guest]

Pierre, Way too funny!!!!!! I bet this made you feel REAL comfortable huh! I

also had this type of pistol style biopsy, but my neph said he tried it out on

Pierre first, and tons of fruit, so should be OK. Bonnie

Pierre Lachaine wrote:When I had my biopsy, the

radiologist had a new pistol-style biopsy needle. He said I was the first

patient he actually used it on, but not to worry, he had been practising on

fruit all week

Pierre

RE: Odd results

Shara,

Mine was a quickie. I was in and out within a few hours. It didn't hurt.

The only complication was when I bled all over the hospital bed. They hadn'

t applied pressure to the right spot!

The regular radiologist was out and I felt like I was the first kidney

biopsy the other radiologist had ever done. The technician kept telling him

how to do it. I think he had out an instruction manual too!

IgA was a positive diagnosis for me. My mistaken Neph at the time kept

saying it was diabetic kidney disease. I am grateful to have IgA, the

alternative was much worse!

Good Luck! I shall send positive vibes from Austin!

Cyndi

[Guest guest]

Hi Shara,

The key thing for us wasn't so much the biopsy procedure which was

relatively easy, but rather getting the results. Like you, my son also went

into it with depressed C3. We had the light microscopy results back the

next day -- and the immunoflourescence and electron microscopy results back

within a couple of weeks. Fortunately, you can get a lot of information

from the light microsopy studies. In the case of MPGN, the light microscopy

is sufficient to provide an initial diagnosis. The immunoflourescence and

electron microscopy studies add more information - such as what type of MPGN

it is.

Cy

Re: Odd results

> Wow, thank you for all of the responses. I've got to remember:

> practice holding breath, no lifting, pee before arrival and limit

> fluids so I wont have to later. Thank you for the great advice. I'll

> let you all know how it goes. - Shara

>

>

> > Shara,

> > With my biopsy, most of my fears came from the use of needles,

> since they freak me

> > out so. I was in the hospital over night and confined to bed for

> the first 8 or 10 hours,

> > I can't recall. When I insisted on getting out of bed to use the

> bathroom around 2 am

> > (girls and bed pans don't mix well) I passed out and was promptly

> told to stay in bed

> > till release.

> >

> > Depending on how fast I got up or out of bed, I did have some pain

> for about two

> > weeks after. It's important to remember not everyone respond to an

> injury or even to

> > pain the same way. I wish you luck. Getting it done and getting to

> a diagnosis is

> > important in moving forward.

> >

> > BTW, I found it helpful to practice holding my breath to the same

> level for brief

> > periods the night before biopsy.

> >

> > peace,

> >

>

>

>

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

>

> To unsubcribe via email,

> iga-nephropathy-unsubscribe

> Visit our companion website at www.igan.ca. The site is entirely supported

by donations. If you would like to help, go to:

> http://www.igan.ca/id62.htm

>

> Thank you

>

[Guest guest]

Yeah I know what you mean. I already have a hard time waiting for

things. Hopefully my doctor will work as quickly with that as he did

with getting the biopsy set up. Thank you for the reassurance. -

Shara

> > > Shara,

> > > With my biopsy, most of my fears came from the use of needles,

> > since they freak me

> > > out so. I was in the hospital over night and confined to bed

for

> > the first 8 or 10 hours,

> > > I can't recall. When I insisted on getting out of bed to use

the

> > bathroom around 2 am

> > > (girls and bed pans don't mix well) I passed out and was

promptly

> > told to stay in bed

> > > till release.

> > >

> > > Depending on how fast I got up or out of bed, I did have some

pain

> > for about two

> > > weeks after. It's important to remember not everyone respond

to an

> > injury or even to

> > > pain the same way. I wish you luck. Getting it done and

getting to

> > a diagnosis is

> > > important in moving forward.

> > >

> > > BTW, I found it helpful to practice holding my breath to the

same

> > level for brief

> > > periods the night before biopsy.

> > >

> > > peace,

> > >

> >

> >

> >

> >

> > To edit your settings for the group, go to our Yahoo Group

> > home page:

> > http://groups.yahoo.com/group/iga-nephropathy/

> >

> > To unsubcribe via email,

> > iga-nephropathy-unsubscribe

> > Visit our companion website at www.igan.ca. The site is entirely

supported

> by donations. If you would like to help, go to:

> > http://www.igan.ca/id62.htm

> >

> > Thank you

> >

[Guest guest]

--Hi Shara,

Iwas diagnosed with IGA at age 31-I am 34 now. My sister had visible

blood in her urine and has also been seeing a nephrologist-her Dr

states that her kidney's are hyperfiltrating now also and told her

she probably doesn't have IGA. my dr says she probably does. her

creatine is normal so they won't do a biopsy. now I am worried after

reading pierre's reply about it being a sign her kidney's are

deteriorating. she doesn't take any meds but has stopped eating meat

and takes fish oil. please let me know how your biopsy turns out.

thanks,

christine

- In iga-nephropathy , " sl_piercetx " <sharareece@g...>

wrote:

> I saw my doctor today at the clinic. He said that the Creatinine

> clearance of 189 indicated that my kidneys are going through

> hyperfiltration. He said this is a common thing in pregnant women

> and diabetics and can cause kidney burn out. As far as I know I'm

> not pregnant or shouldn't be. I'm going to take a test just in

case,

> but it's not likely. What is strange is that they seemed to have

> never slowed down after I had my son. He said my results are not

> evident of IgA, but he really has no idea what is going on...So, I

> asked him when I might be able to have the biopsy done and he

> said " how about next Tuesday. " So that's when I am tenatively

> scheduled for it. It's always a strange thing to have the doctor

> say...umm yeah this is weird I don't know what's going on. - Shara

[Guest guest]

, yeah that sounds a lot like me. I don't know how they

tell your kidneys are hyperfiltrating... Has she had the

comprehensive tests done? (24 hour urine, complement components or

whatever?) I'll will post after I get the results...I am looking

forward to what my doctor says especially since the last thing he

said is, " I have no idea what is going on. " - Shara

> > I saw my doctor today at the clinic. He said that the Creatinine

> > clearance of 189 indicated that my kidneys are going through

> > hyperfiltration. He said this is a common thing in pregnant

women

> > and diabetics and can cause kidney burn out. As far as I know

I'm

> > not pregnant or shouldn't be. I'm going to take a test just in

> case,

> > but it's not likely. What is strange is that they seemed to have

> > never slowed down after I had my son. He said my results are not

> > evident of IgA, but he really has no idea what is going on...So,

I

> > asked him when I might be able to have the biopsy done and he

> > said " how about next Tuesday. " So that's when I am tenatively

> > scheduled for it. It's always a strange thing to have the doctor

> > say...umm yeah this is weird I don't know what's going on. -

Shara

[Guest guest]

, just an FYI regarding your sister and her " normal creatinine " . I

hope her neph is watching her closely regarding proteinuria and urine pro/creat

ratio, as well as tight B/P control. I also have a " normal " serum creatinine

(0.9 to 1.0) but have several markers for progression of Ig A to end stage renal

disease (I have 5 out of 9 markers: hypertension, moderate proteinuria (was

around 3 grams per day), glomerular sclerosis, interstitial fibrosis, and Ig A

deposits in the periphery of the glomerular basement membrane. My neph was

really glad he did the biopsy, because there was no way to determine otherwise

that I had about 33% dead kidney cells without the biopsy. Morale of the story:

" normal creatinine " is not always a true picture of renal function. GFR is

fairly good. Even a creatinine clearance is not always the best to determine

renal function. I also had hyperfiltration in the beginning of work up for

renal disease (but certainly not now). In my case renal

biopsy was indicated due to worsening proteinuria, and declining urine

pro/creat ratio, and a positive lupus test. They wanted to esp. see if was

related to lupus nephritis or Ig A, or something else. Technically, " renal

biopsy is indicated when all three of the following conditions are met: (1) the

cause cannot be determined or adequately predicted by less invasive diagnostic

procedures, (2) the signs and symptoms suggest parenchymal disease that can be

diagnosed by patholoci evaluation, and (3) the differential diagnosis includes

different diseases that have different treatments, different prognoses or both. "

(Primer on Kidney Diseases, 3rd ed.Arthur Greenberg et. al National Kidney

Foundation). (An awesome book for anyone interested, but written in medical

terminology). Anyway, better run, I'm having way too much fun talking to all of

you on site, and not getting my buns to work. Hope that gives you perhaps

another perspective on serum creatinines and the potential need to

pursue renal biopsy. I unfortunately had procrasinated mine, cause I did not

want anyone poking a needle into my kidney, but now wish I had pursued this a

little earlier, may have preserved a little more renal function over the long

haul. Talk to you later. Bonnie

gncclevenger wrote:

--Hi Shara,

Iwas diagnosed with IGA at age 31-I am 34 now. My sister had visible

blood in her urine and has also been seeing a nephrologist-her Dr

states that her kidney's are hyperfiltrating now also and told her

she probably doesn't have IGA. my dr says she probably does. her

creatine is normal so they won't do a biopsy. now I am worried after

reading pierre's reply about it being a sign her kidney's are

deteriorating. she doesn't take any meds but has stopped eating meat

and takes fish oil. please let me know how your biopsy turns out.

thanks,

christine

- In iga-nephropathy , " sl_piercetx " <sharareece@g...>

wrote:

> I saw my doctor today at the clinic. He said that the Creatinine

> clearance of 189 indicated that my kidneys are going through

> hyperfiltration. He said this is a common thing in pregnant women

> and diabetics and can cause kidney burn out. As far as I know I'm

> not pregnant or shouldn't be. I'm going to take a test just in

case,

> but it's not likely. What is strange is that they seemed to have

> never slowed down after I had my son. He said my results are not

> evident of IgA, but he really has no idea what is going on...So, I

> asked him when I might be able to have the biopsy done and he

> said " how about next Tuesday. " So that's when I am tenatively

> scheduled for it. It's always a strange thing to have the doctor

> say...umm yeah this is weird I don't know what's going on. - Shara

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[Guest guest]

Hi Bonnie,

Do you know if it is possible to do a protein/creatinine ratio if all you

have is a random sample and not a 24-hour one? I picked up a copy of my labs

yesterday and it said protein was 4mg and creatinine was 32mg and I'm trying to

figure out what that means. Can you figure out GFR from that ratio? Thanks

for the info on when a biopsy is needed. My serum creatinine is the same as

yours and I would really like to have a biopsy done to get a better idea of what

my kidney function is really like. But now I better understand why my neph is

holding off on it. Take care.

Cheryl

[Guest guest]

Hi Cheryl,

My doctor does a protein/creatinine ratio off of a random sample, but it will

not give you GFR or Creatinine clearance. The only way to get those is with

a 24 hour clearance, although GFR can be estimated from the MDRD equation. I

will put the link here for you.

http://nephron.com/mdrd/default.html

In a message dated 9/4/2004 2:41:13 PM Pacific Daylight Time,

Chucktkn@... writes:

> Hi Bonnie,

> Do you know if it is possible to do a protein/creatinine ratio if all you

> have is a random sample and not a 24-hour one? I picked up a copy of my

> labs

> yesterday and it said protein was 4mg and creatinine was 32mg and I'm trying

> to

> figure out what that means. Can you figure out GFR from that ratio? Thanks

>

> for the info on when a biopsy is needed. My serum creatinine is the same as

>

> yours and I would really like to have a biopsy done to get a better idea of

> what

> my kidney function is really like. But now I better understand why my neph

> is

> holding off on it. Take care.

> Cheryl

[Guest guest]

Hi ,

That gives me so much encouragement that your creatinine has held steady at

4.5 for so long! I hope your sister can get a second opinion and protect her

renal function.

In a message dated 9/4/2004 5:19:21 PM Pacific Daylight Time,

GNCCLEVENGER@... writes:

> Oh, My creatine has

> stayed 4.5 since I was diagnosed-I am sure due to the zestril.

>

> thanks for listening,

> chrisitine

>

> and I hope you are feeling better.

>

[Guest guest]

Hi ,

Thanks for giving me the link to the GFR calculator. I just had one question

about it. When I used the regular version and punched in my serum creatinine

of 1.0, it said I had 66% function. But when I used the extended version and

added my serum urea nitrogen value of .9, it said I had 107.8 function. Does

the BUN value really make that much of a difference in your GFR? I'm just

confused in how one number can make that much difference. Thanks for helping me

try to understand this.

Cheryl

[Guest guest]

---

Hi Shara,

My sister is 21 now and has had blood and or protein found by

urinalysis for approx 2 yrs now. She also was peeing blood

originally. I never had that happen to me. I've had blood microscopic

in my urine since I was 20-Iwas diagnosed 3yrs ago and am 34 now. I

was told at age 20 some women have bllod-don't woory, so I never

followed up and when I was diagnosed I had had headaches and my BP

was high and my creatine was 4.5. I told my sister what pierre said

about hyperfiltration. Her nephrologist at first said she probably

has IGA then said maybe FSGS but won't do a biopsy because her

creatine is normal. I know she has had a 24hr urine and her

filtration rate was 180. She is going to see if she can get a second

opinion at my nephrologist at university of MD. I only hope that she

can prevent kidney function from declining. Oh, My creatine has

stayed 4.5 since I was diagnosed-I am sure due to the zestril.

thanks for listening,

chrisitine

and I hope you are feeling better.

In iga-nephropathy , " sl_piercetx " <sharareece@g...>

wrote:

> , yeah that sounds a lot like me. I don't know how they

> tell your kidneys are hyperfiltrating... Has she had the

> comprehensive tests done? (24 hour urine, complement components or

> whatever?) I'll will post after I get the results...I am looking

> forward to what my doctor says especially since the last thing he

> said is, " I have no idea what is going on. " - Shara

>

> > > I saw my doctor today at the clinic. He said that the

Creatinine

> > > clearance of 189 indicated that my kidneys are going through

> > > hyperfiltration. He said this is a common thing in pregnant

> women

> > > and diabetics and can cause kidney burn out. As far as I know

> I'm

> > > not pregnant or shouldn't be. I'm going to take a test just in

> > case,

> > > but it's not likely. What is strange is that they seemed to

have

> > > never slowed down after I had my son. He said my results are

not

> > > evident of IgA, but he really has no idea what is going

on...So,

> I

> > > asked him when I might be able to have the biopsy done and he

> > > said " how about next Tuesday. " So that's when I am tenatively

> > > scheduled for it. It's always a strange thing to have the

doctor

> > > say...umm yeah this is weird I don't know what's going on. -

> Shara

[Guest guest]

I had been seeing a urologist for this problem until I took it upon

myself to move things along. When I told the dietitian and some of

the nurses at the clinic where I work what was going on they said I

might just mention it to the Medical Director (my neph) and see what

he says (he likes to answer people's questions even if they aren't

patients). So I mentioned it to him and he asked me to get all my

records and make an appointment with him...and that's where I am at

this point. I know all doctors are different but I can't imagine one

nephrologist taking this so seriously and the other not. Of course I

told my neph that I plan on having more children in the future and

that if this is something that might progress I need to know about

it now. That may have aided his decision. He did mention in his new

patient eval. that " as she is considering more pregnancies, then it

may beome more important to perform a biopsy of the kidney to

establish diagnosis, but I am not sure that would be necessary on an

immediate basis. " Maybe your sister could tell them she wants to get

pregnant....I am really anxious to see what he has to say. - Shara

> > > > I saw my doctor today at the clinic. He said that the

> Creatinine

> > > > clearance of 189 indicated that my kidneys are going through

> > > > hyperfiltration. He said this is a common thing in pregnant

> > women

> > > > and diabetics and can cause kidney burn out. As far as I

know

> > I'm

> > > > not pregnant or shouldn't be. I'm going to take a test just

in

> > > case,

> > > > but it's not likely. What is strange is that they seemed to

> have

> > > > never slowed down after I had my son. He said my results are

> not

> > > > evident of IgA, but he really has no idea what is going

> on...So,

> > I

> > > > asked him when I might be able to have the biopsy done and

he

> > > > said " how about next Tuesday. " So that's when I am

tenatively

> > > > scheduled for it. It's always a strange thing to have the

> doctor

> > > > say...umm yeah this is weird I don't know what's going on. -

> > Shara