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Re: C. Glabrata

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> My GYN wanted to try me on Lamasil (orally) just incase in had a

hard to get rid of fungus. I couldnt take it since no insurance and

cash would have been over $300 for 30.

> I wonder if it would kill off C. Glabrata. Anyone know?

> Candi~

>

Nizoral works for C. Glabrata. Diflucan WILL work but because

glabrata is resistant, you have to take higher doses for longer

periods of time.

http://www.angelfire.com/hi/HeidiHomePage/index11.html

Here is one former members success story with C. Glabrata/Nizoral

Lynn

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> I was just wondering if Lamisil would be another option for C.

>Glabrata. Since its new and may not be resistant to it yet.

I found this...Lynn

http://www.thevbook.com/chapter10.html

Boric acid has to be used as directed. It is not to be taken by

mouth; the capsules must be kept out of reach of children. Its safety

in pregnancy has not been studied, and so its use in pregnancy is not

recommended. High dosages can lead to severe burns. It is absorbed

through damaged skin and wounds but does not penetrate intact skin.

When used vaginally, it stays there and does not travel through the

body.43 When boric acid fails, flucytosine (Ancobon) cream or

amphotericin cream may be used for a fourteen-day regimen. These are

antifungals that are not commonly used, so they have to be made up by

a special compounding pharmacy. When all else has failed against

Candida glabrata, terbinafine (Lamisil), a new drug out for the

treatment of the fungus that invades nails, is occasionally used; it

may work, not because it is a great treatment for C. glabrata but

because it is a new molecular structure that the yeast has not yet

encountered.

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>I know Nizoral will work. I took that, dont know if I had C. G. or not. I think

Maureen used Nizoral as well. I felt some better after using it for 2 weeks

though. thats why I am cleansing now. She wanted me to take Lamisil though in

case it was a stubborn strain of fungus. She wasnt specific on which strain

though. I was just wondering if Lamisil would be another option for C. Glabrata.

Since its new and may not be resistant to it yet.

It is not advisable to take an anti-fungal just in case it is fungus. Some of

those antifungals just make the situation worse. Be sure you need it before

you take it.

Ora

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>I put my faith in my GYN. She agrees that you can have fungal problems and that

they can cause vulvar problems even if a vaginal culture is negative.

http://www.ichelp.com/FeatureArticles/YeastInfectionAreYouSure.html

A frequently misdiagnosed, little known, yet apparently quite

common condition, called cytolytic vaginosis (CV), is often confused

with a true yeast infection. However, the two actually share almost

nothing in common, except for symptoms. Like a yeast infection,

cytolytic vaginosis is characterized by itching and burning, painful

intercourse and a slight discharge. It also tends to become more

symptomatic premenstrually. Since the symptoms are so similar,

physicians often mistake cytolytic vaginosis for a yeast infection.

To distinguish CV from other conditions, the physician must rule out

other possible causes of symptoms, such as vulvodynia, bacterial

vaginosis (an infection of the vagina caused by the bacterium

gardnerella) and trichomonas. This can be done with a high-powered

microscopic examination of vaginal secretions. Herein lies the biggest

clue to differentiate between a yeast infection and CV: Under a

microscope, candida has a distinctive appearance—abundant yeast-like

fungal growth, and a low number of lactobacilli (the so-called " good

bacteria " ). CV, on the other hand, presents with an overabundance of

lactobacilli, few yeast-like growths, and few white cells. It is thought

that CV is an overgrowth of normal vaginal bacteria (lactobacilli). The

vagina has both lactobacilli and candida (as well as many other

organisms) as part of its normal, healthy flora. It is all a matter of

keeping the proper balance between these....which involves pH.

The overgrowth of organisms that occurs with CV causes the vaginal

environment to become too acidic (low pH). This damages the epithelial

cells of the vagina, and can cause itching, burning and irritation.

Candida overgrowth tends to occur in an alkaline environment (high pH).

This, too, can result in pain, itching and burning.

Management of CV consists of stopping all antifungal treatments (oral

and intravaginal), using pads instead of tampons so that menstrual blood

can flow unimpeded and re-balance the pH of the vagina, and taking

baking soda sitz baths. It may also be a good idea to stop taking any

probiotic supplements that you may be using, such as lactobacillus

acidophilus. Yogurt has also been found to exacerbate CV. In other

words, everything you have been told to do to treat a yeast infection is

the wrong approach for CV!

The vaginal flora is a complex ecosystem that requires checks and

balances. Many different things, from birth control pills and

antibiotics, to diet, can have an effect on the environment of the

vagina. If you think you may have CV, please consult a physician

knowledgeable about this condition (as well as about IC) before

undertaking any new course of therapy.

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