Guest guest Posted October 15, 2004 Report Share Posted October 15, 2004 Dear ; Here's my son's blood work (stage II PSC) for comparison with yours: Albumin: 4.2 (5/04); 4.0 (7/04) Total Bilirubin: 1.7 (5/04); 1.2 (7/04) ALT: 113 (5/04); 98 (7/04) AST: 51 (5/04); 73 (7/04) ALK: 371 (5/04); 293 (7/04) He did not have prothrombin time (INR) run in these blood tests. In the long run, I think it is albumin and prothombin time (INR) that are the most important measures of liver function. Best regards, Dave (father of (19); PSC 07/03; UC 08/03) > Hey everyone, > > I just a received the latest copy of my blood tests and was wondering just really how high things truly were. Yes I know what the normal levels are but if some of you who are close to transplant or have had transplant could let me know kinda what your range is to give me some idea of maybe how I am progressing. I would really appreciate it. > > Here are my results: > > Bilirubin: 1.7 > Alkaline Phosphate Serun: 444 > AST: 84 > ALT: 123 > > > Thank You, > > 25, Alabama, Diagnosed with PSC at age 16 > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2004 Report Share Posted October 15, 2004 , question. As PSC progresses will the albumin get high or low? Bill's is low.I know that the other numbers climb. Also is the only way to know what stage you are in by the liver biopsy? Thanks Lee > > > Dear ; > > Here's my son's blood work (stage II PSC) for comparison with yours: > > Albumin: 4.2 (5/04); 4.0 (7/04) > Total Bilirubin: 1.7 (5/04); 1.2 (7/04) > ALT: 113 (5/04); 98 (7/04) > AST: 51 (5/04); 73 (7/04) > ALK: 371 (5/04); 293 (7/04) > > He did not have prothrombin time (INR) run in these blood tests. In > the long run, I think it is albumin and prothombin time (INR) that > are the most important measures of liver function. > > Best regards, > > Dave > (father of (19); PSC 07/03; UC 08/03) > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2004 Report Share Posted October 15, 2004 Hi Lee; Good questions. As PSC progresses serum albumin gets lower. http://www.nlm.nih.gov/medlineplus/ency/article/003480.htm " Albumin is the protein of the highest concentration in plasma. Albumin transports many small molecules in the blood (for example, bilirubin, calcium, progesterone, and drugs). It is also of prime importance in maintaining the oncotic pressure of the blood (that is, keeping the fluid from leaking out into the tissues). This is because, unlike small molecules such as sodium and chloride, the concentration of albumin in the blood is much greater than it is in the extracellular fluid. Because albumin is synthesized by the liver, decreased serum albumin may result from liver disease. It can also result from kidney disease, which allows albumin to escape into the urine. Decreased albumin may also be explained by malnutrition or a low protein diet. " " The normal range is 3.4 to 5.4 g/dL. " It is possible that 's low albumin is related to the malnutrition that he has been experiencing because of UC. I hope that is doing better this week. I believe that the only way to stage PSC is by biopsy, but some groups are better at this than others. For instance, when had a liver biopsy they were unable to determine whether he had PSC (or stage it) at IU. However, when we had the biopsy slides sent to Mayo, they were able to stage it at stage II. Best regards; Dave (father of (19); PSC 07/03; UC 08/03) > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2004 Report Share Posted October 16, 2004 Thanks Dave, you are a fountain of information as usual. It's funny but I find it easier to ask you while I am thinking of it at the computer than to ask my husband later. I think this is because I am afraid of getting us both upset just by talking about it. It's like we need a mental rest after all that we went through this summer. I will hope that Bill's low albumin is from the nutrition issue. Bill has started his decline on the prednisone and I am hoping that his increased appetite will remain. My best to you as always. Lee I hope survived all his midterms! > > > Hi Lee; > > Good questions. As PSC progresses serum albumin gets lower. > > http://www.nlm.nih.gov/medlineplus/ency/article/003480.htm > > " Albumin is the protein of the highest concentration in plasma. > Albumin transports many small molecules in the blood (for example, > bilirubin, calcium, progesterone, and drugs). It is also of prime > importance in maintaining the oncotic pressure of the blood (that is, > keeping the fluid from leaking out into the tissues). This is > because, unlike small molecules such as sodium and chloride, the > concentration of albumin in the blood is much greater than it is in > the extracellular fluid. > > Because albumin is synthesized by the liver, decreased serum albumin > may result from liver disease. It can also result from kidney > disease, which allows albumin to escape into the urine. Decreased > albumin may also be explained by malnutrition or a low protein diet. " > > " The normal range is 3.4 to 5.4 g/dL. " > > It is possible that 's low albumin is related to the > malnutrition that he has been experiencing because of UC. I hope that > is doing better this week. > > I believe that the only way to stage PSC is by biopsy, but some > groups are better at this than others. For instance, when had > a liver biopsy they were unable to determine whether he had PSC (or > stage it) at IU. However, when we had the biopsy slides sent to Mayo, > they were able to stage it at stage II. > > Best regards; > > Dave > (father of (19); PSC 07/03; UC 08/03) > > > > >> > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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