Guest guest Posted September 8, 2011 Report Share Posted September 8, 2011 Hi Pamela, Here's an extract from an email I received from Dr Zagon, hope this helps:- Once one realizes that LDN is nothing more than an instrument to evoke the opioids (and receptors), and these opioids/receptors are what is really doing the good things, then they start to realize that less is more. It is interesting that the 4.5 mg story came out of the Bihari era. When I first recommended 3-10 mg to him, I suggested he take a 50 mg tablet and take 1/5 or less. The next day he called me and said that it worked splendidly in the sense he felt wonderful when he arose in the morning. After that I lost touch for a while, and only when patients were not responding to LDN did he send them my way. The vast majority needed to reduce their 4.5 mg to 3 mg. Some had to take 3 mg every other day - or every 3rd day. Again, this was counter to these folks thinking that it was LDN that did the trick. So, keep spreading the real story. And that includes the myth that LDN needs to be taken in the evening. I told Bihari this because I reasoned that for 4-6 hr the patient would be without endorphins that would work (the naltrexone would interfere with function in making one feel good). So I advised him to take this in the evening and sleep through the possible uncomfortable feeling of endorphin deprivation. This led Bihari and followers to a story about circadian rhythm as the reason. Nonsense, the endorphins - and especially OGF (met-enkephalin) does not have a circadian rhythm. And people who took my advice and used it in the morning found out that they did just as well. Best, Jayne Crocker LDNNow logo the one to use www.LDNNow.com LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. < Dr Steele MBE, talking about LDN <http://www.ipetitions.com/petition/ldnnow/> Important! Please sign our LDN petition to the European Parliament by clicking here Quote Link to comment Share on other sites More sharing options...
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