Guest guest Posted February 11, 2004 Report Share Posted February 11, 2004 Hi *~, Wednesday, February 11, 2004, 6:33:26 PM, you wrote: ~O~> However that being so does not change the meaning of the study which found ~O~> that the combination T4,T3 was of much greater benefit than the T4 alone as ~O~> shown on a series of tests the participants took on each. They especially ~O~> mentioned the need for T3 by the brain. Surprise, Surprise:-)) If you took the NEJM study to any mainstream endocrinologist worth his salt, she/he would point to the two recent studies in The Journal of Clinical Endocrinology & Metabolism to refute its conclusions. (Be prepared!!!) I have read that T3 does *not* cross the blood-brain barrier (at least not in rats), and thus, if you wanted to increase the T3 concentration in the brain that you would have to take more T4. However, T3 is used to augment antidepressants in treatment-resistant depression. I suspect that there must be some difference between rat brains and human brains. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2004 Report Share Posted February 11, 2004 > > If you took the NEJM study to any mainstream endocrinologist worth his > salt, she/he would point to the two recent studies in The Journal of > Clinical Endocrinology & Metabolism to refute its conclusions. (Be > prepared!!!) > > > I have read that T3 does *not* cross the blood-brain barrier (at least > not in rats), and thus, if you wanted to increase the T3 concentration > in the brain that you would have to take more T4. However, T3 is used > to augment antidepressants in treatment-resistant depression. I > suspect that there must be some difference between rat brains and > human brains. Wow! This is good stuff! I wonder if patients reporting they feel better on T-3 are experiencing a placebo effect. I'm always worried about that in myself. I feel great right now, but I'm thinking, what if it's just placebo effect and it goes away? I know for a fact that my body does the placebo effect thing because whenever I take an antihistamine for an allergy attack (sneezing, itchy eyes, etc.) I immediately stop sneezing the minute I take the pill. It could not have gotten into my system in that fraction of a second while I swallowed it, so my only explanation is placebo response. I guess placebo effect isn't all bad. Whatever works, works. I just can't stop being afraid this good feeling, this feeling of being free of depression, free of aches and pains etc., is going to be taken away from me. I just don't know right now if it's placebo effect or not. Some of the things - body temp, pulse rate - seem to not be subjective, but I know the mind can influence the body. I got really mad at doctors telling me my symptoms were all in my head because my TSH was normal. The truth is, though, they might have all been in my head - my subconscious might have even been controlling my pulse rate and temp and causing the ulcers in my bladder - it's possible - but even if it WAS all in my head, the psychiatrists and antidepressants and pain pills weren't fixing anything so it was time to try something else. Oh, man, I am so sleepy, I want to go to bed but I'm so excited by this information, this discussion, I don't want to miss anything! P.S. I wrote to Dr. Mercola (well, to his support staff really) and tried to tactfully ask if there had been an editing error. I told them that I really enjoyed his website and found it helpful and was worried an editing error might damage his credibility and thus his ability to reach and help audiences. Don't know if they will reply or fix it, guess we can wait and see. Gentle Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2004 Report Share Posted February 11, 2004 Very well put ~OM~ very well put..... HUgs...PattiSue NEJM Study Hi EveryOne, is right the NEJM study that Dr. Mercola quoted and from whom I took the information did not specify " Armour " or " Synthroid " . That was evidently Dr. Mercola's interpretation of it. I got what I had on my webpage from Dr. Mercola not from the original study. I just looked up the original study and actually they used two look alike drugs made for the study one containing just T4 (like Synthroid does) and one containing T4 plus T3 (like Armour does). However that being so does not change the meaning of the study which found that the combination T4,T3 was of much greater benefit than the T4 alone as shown on a series of tests the participants took on each. They especially mentioned the need for T3 by the brain. Surprise, Surprise:-)) Peace, Love and Harmony, Bev Thyroid-Adrenal Connection: Information and Resources http://www.bestweb.net/~om/thyroid Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2004 Report Share Posted February 11, 2004 Gee, I would hope my brain is different than a rats LOL Hugs...PattiSue Re: NEJM Study Hi *~, Wednesday, February 11, 2004, 6:33:26 PM, you wrote: ~O~> However that being so does not change the meaning of the study which found ~O~> that the combination T4,T3 was of much greater benefit than the T4 alone as ~O~> shown on a series of tests the participants took on each. They especially ~O~> mentioned the need for T3 by the brain. Surprise, Surprise:-)) If you took the NEJM study to any mainstream endocrinologist worth his salt, she/he would point to the two recent studies in The Journal of Clinical Endocrinology & Metabolism to refute its conclusions. (Be prepared!!!) I have read that T3 does *not* cross the blood-brain barrier (at least not in rats), and thus, if you wanted to increase the T3 concentration in the brain that you would have to take more T4. However, T3 is used to augment antidepressants in treatment-resistant depression. I suspect that there must be some difference between rat brains and human brains. Quote Link to comment Share on other sites More sharing options...
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