Guest guest Posted February 12, 2004 Report Share Posted February 12, 2004 Hi EveryOne, I just checked and ZRT has Free T4 and Free T3 spot tests for $60.00 each. About Thyroid Hormones and Testing http://www.bloodspottest.com/thyroid_test.html More than 10 million Americans have been diagnosed with thyroid disease, and another 13 million people are estimated to have undiagnosed thyroid problems in the U.S. alone. A February, 2000 research study found that the estimated number of people with undiagnosed thyroid disease may be 10 percent – a level that is double to what was previously thought. Hypothyroidism, or low thyroid, is a very common condition. It is estimated that 3 to 5% of the population has some form of hypothyroidism. Women are at greatest risk, developing thyroid problems seven times more often than men. Low thyroid increases with age and in fact, hypothyroidism is most common in women during the menopausal years; approximately 26% of women in or near menopause are diagnosed with hypothyroidism. Notes: In a recent study among patients taking thyroid medication, only 60% were within the normal range for TSH. The fact that 40% of patients, a number that translates to millions of Americans, are already taking thyroid hormone and being treated by a doctor but are still not within the expected normal TSH range is of great concern. Not only does this show the need for more frequent monitoring and adjustment of dosages -- versus the standard recommendation of maximum yearly testing – but may in fact suggest that there are serious inadequacies in the current therapies, which primarily rely on synthetic thyroid hormone replacement known as levothyroxine (brandnames Synthroid, Levoxyl, Levothyroid, Eltroxin). The inadequacy of the standard therapy in relieving symptoms is addressed in the February 11, 1999 New England Journal of Medicine landmark T3 Thyroid Drug Study which found that the majority of patients studied felt better on a combination of two drugs, including levothyroxine (T4) and T3, and NOT solely levothyroxine/T4 (i.e., Synthroid or Levoxyl) alone. The addition of T3 was found to help relieve depression, brain fog, fatigue and other symptoms. The thyroid gland produces 2 hormones: T4 (80%) and T3 (20%). Each thyroid hormone is made up of a tyrosine (protein) surrounded by four (T4) or three (T3) iodines. T4 is the “inactive,” while T3 is the “active” component. Thyroid hormones set metabolic activity and are thus responsible for the speed at which every enzyme action in the body takes place. When the thyroid gland produces T4, it is taken up by every cell in the body, and converted into T3 which produces activity within the cell. When thyroid hormones are transported in the blood they are “bound” to a protein, Thyroid Binding Globulin (TBG), that temporarily holds them inactive. This protein may be manipulated by many illnesses and medications. Therefore, the measurement of the unbound, “free” levels of T3 and T4 thyroid hormones as conducted in blood spot testing at ZRT Laboratory is the most accurate. Functional Thyroid Deficiency when free T3, free T4, and TSH are within normal range but symptoms (particularly a low basal temperature) are consistent with a hypothyroid state, a functional thyroid deficiency may exist. In this case, adequate thyroid is present but the tissues fail to respond. This functional thyroid deficiency or “thyroid resistance” is often caused by autoimmune thyroiditis (Hashimoto’s), which can be identified using Thyroid Peroxidase Antibody – TPO testing—available as part of the blood spot thyroid panel at ZRT Laboratory. Other causes of functional thyroid deficiency are estrogen dominance (excessive estrogens in the absence of adequate progesterone), low anabolic steroids (testosterone and DHEAS), and/or adrenal imbalance (low or high cortisol). If thyroid resistance is suspected (i.e. thyroid tests are normal but symptoms indicate hypothyroidism), saliva testing) for estradiol, progesterone, testosterone, DHEAS and am/pm cortisol is strongly recommended. For more information visit www.salivatest.com Quote Link to comment Share on other sites More sharing options...
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