Re: Metformin and Glyburide

[Guest guest]

The metformin help the cell to abosrb insulin. In other words, metformin

tackle the porblem of the cells being insulin resistant. I advise taking

the metformin at night to keep a steady sugar level throu the night.

Victor

ð\-

Metformin and Glyburide

> To anyone on the group that takes both these meds, I'm curious if your

> experience is similar to mine. I take Metformin with each meal and am

> supposed to take a Glyburide tab in the morning, and also take one with

the

> evening meal, unless I notice a pattern where sugars drop too low with the

> Glyburide, in which case I skip that med for the night dose.

>

> In my experience with these two meds, Metformin seems to be OK except I

hate

> taking it three times a day, and Glyburide is rather fast-acting but when

I

> take it in the evening my sugar can dive sometimes way too low, requiring

me

> to bounce back half a glucose tablet. It's like I'm constantly playing

> tug-o-war where some days control is easy and other days it almost seems

> like I have a hard time keeping the sugar up enough before it b ottoms

out,

> usually during things like a long workday or when it gets really hot.

>

> And remember not too long ago I wrote about my experience where I'd be out

> somewhere and my sugar would just suddenly drop for no reason, and I'd

solve

> it by taking half a glucose tablet? It turns out that yes, as I suspected,

> the sugar would actually drop rather suddenly down to levels between 45-55

> and a glucose tablet rescued me. But one time when this happened I took a

> Metform pill instead just to see if this made any direct difference rather

> than the glucose tablet, and same thing, my sugar level ROSE just enough

to

> be out of harm's way. I have not seen my doc since that episode yet but

> intend to bring this up to him. What does the Metformin actually do here

in

> order to balance out the sugar problem? I would have thought it just

helped

> to lower the sugar but was surprised it had the opposite effect when I

> substituted it for the glucose tablet. It gave me a nice reading of 78

after

> less than 15 minutes and 90 before half an hour. I don't get that one.

>

> When I switched from Actos to Glyburide/Metformin, I was hoping this would

> help me lose weight and keep good control of my sugars but it's a lot more

> work keeping control with these two meds than with Actos. But of course

> Actos isn't fully covered by Medicare Part D as you pay a high copay for

it.

> Back to square one.

>

> Now I should point out one thing I do like about Metformin is that if I go

> out for a late-night snack with friends, I do know that would up my sugar

> too much come morning time but if I do take a snack, then take a

Metformin,

> my morning fasting sugar is normal at 100 or below.

>

> Any thoughts on this?

>

> Thanks,

>

> Mister Bill

>

>

>