Re: B-12

October 10, 2006

Are you experiencing fatigue or lack of energy?

Now there is an easy and effective solution.

The Vitamin B-12 Patch is a revolutionary product developed to supply the body

with vitamin B12 needed for:

Increased energy

Restored mental clarity

Help with memory loss

Reduced daily stress and irritability

Absorbing vitamin B12 in your body is not easy. Until now.

Most multivitamin pills only contain 100-200 mcg of the cyanocobalamin form of

B12. This must then be converted to methylcobalamin or adenosylcobalamin before

it can be used by the body. The actual absorption of B12 is a serious problem

with oral supplements. Swallowing 500 mcg of Vitamin B12 can result in

absorption of as little as 1.8 mcg, so most oral supplements do not provide an

adequate daily intake! Sublingual forms of vitamin B12 are available, but there

is no proof (nor is there any reason to expect) that they offer any advantage to

oral supplements (i.e. a sublingual preparation is eventually swallowed). The

Vitamin B-12 Patch is the most effective solution.

Doctors know the health benefits of the B vitamin family and have administered

vitamin B12 shots to patients for years and they've seen remarkable results.

However the shots require a prescription and can be painful and expensive. With

the Vitamin B-12 Patch, you simply put a small patch on once per week for up to

24 hours. This patent pending system helps your body get the maximum absorption

of the vitamin B12 nutrients into your system—effective as the shot and without

the pain.

The Vitamin B-12 Patch is safe, efficient and inexpensive. No more feeling

sluggish, tired, down, or forgetful. The Vitamin B-12 Patch gives you the

increased energy and stamina you need to do the things you want to do. Order

the Vitamin B-12 Patch today and help:

Regain the energy of your youth

Free yourself of daily stress and anxiety

Live a happier, more productive life

Restore your mental clarity and avoid memory loss

Read what customers are saying...

" I have a chronic b12 deficiency and must take supplements to avoid the

problems that arise from deficiency of that vitamin. I tried your product and I

can say it is the best I've ever tried, far exceeding sublingual tablets (which

I do not like due to their artificial sweeteners) or even intranasal gel. In

fact you receive the benefits of injections without the problems encountered

using that system. I saw a great effect within about 24 hours. I am going to

order a much larger supply. Thank you for your brilliant innovation! " -

from Easton, Pennsylvania

Pugh wrote: Rethinking & Clarifying the

B12 Issue

by Dr. Vivian V. Vetrano

[vetrano.cjb.net]

There is no such thing as a deficiency of vitamin B12, even in 100%

raw vegans. They do not have to eat dirt, animal products, or take

pills to secure coenzymes of B12. Bacteria in the intestinal tract

make it for us, and the metabolically usable and necessary forms of

coenzyme B12 are contained in unprocessed, fresh natural plant

foods, particularly in nuts and seeds. The real problem in so-called

B12 deficiency is a failure of digestion and absorption of foods,

rather than a deficiency of the vitamin itself.

Vitamin B12 coenzymes are found in nuts and seeds as well as in many

common greens, fruits, and many vegetables. If we ate 100 grams of

green beans, beets, carrots, and peas we would have half of our so-

called daily minimum requirement of Vitamin B12 coenzymes, provided

that our digestion and absorption are normal. From Rodale's The

Complete Book of Vitamins, page 236 we find the following

clarification: " As you know, the B complex of vitamins is called

a `complex' because, instead of being one vitamin, it has turned out

to be a large number of related vitamins, which appear generally in

the same foods. "

A little publicized source of active Vitamin B12 coenzymes is from

bacteria in the mouth, around the teeth, in the nasopharynx, around

the tonsils and in the tonsilar crypts, in the folds at the base of

the tongue, and in the upper bronchial tree. This source alone will

supply sufficient quantities of Vitamin B12 coenzymes for the very

small requirement of total vegetarians, especially considering that

their needs for this vitamin are not as great as for those on

conventional diets.

I have studied this issue thoroughly, and have learned that

biochemists, neutraceutical scientists, and many writers mistakenly

use the term Vitamin B12 for cyanocobalamin, which is not usable by

the body but is included in all vitamin B12 supplements. When

speaking of Vitamin B12 they are referring to the semisynthetic

Vitamin B12 (cyanocobalamin) that initially was contaminated with

poisonous cyanide during its chemical extraction from animal

tissues. Carbon columns are used during the extraction process and

the carbon combines with nitrogen from the medium forming the

poisonous cyanocobalamin, that scientists insist on calling Vitamin

B12. The original method used to extract Vitamin B12 from its

sources included heating the medium in a weak acid, the addition of

cyanide ion, and exposure to light. In this process the coenzymes

were converted to cyanocobalamin, yet this was overlooked. (Review

of Physiological Chemistry, Harper, Harold A., Lange Medical

Publications, New York, 1977, page l81. Also refer to Cobalamin:

Biochemistry and Pathophysiology, Wiley. N. and F. Sicuteri, New

York, 1972.) Moreover, in the manufacture of vitamin supplements,

cyanide is added to the medium because the carbon and nitrogen are

needed to form large molecules as are found in vitamins; and,

additionally, they need it to extract the B12 from fermentation

liquors and liver homogenates. Carbon is needed in great quantities

when making vitamins or any other manufactured vitamin or substance

that mimics the natural vitamin that normally contains a lot of

carbon.

The two Vitamin B12 coenzymes known to be metabolically active in

mammalian tissues are 5-deoxyadenosylcobalamin and methylcobalamin

(methyl-B12). When extracted in light, these two coenzymes undergo

photolysis and are destroyed. Natural B12 is found solely in plants

and animals, and that is the only form that can be called " coenzyme

B12. "

If an animal or individual is given cyanocobalamin the body removes

the cyanide because it is not usable as a coenzyme and it is toxic.

Then the cobalt of the former cyanocobalamin can combine with other

nontoxic substances and actually form Vitamin B12 coenzymes that are

usable by the body. These normally existing Vitamin B12 coenzymes

are labile and break down easily unless inside living tissue.

Potassium in the body can react with the cyanide found in

cyanocobalamin – the " Vitamin B12 " – and form toxic potassium

cyanide (KCN). Potassium cyanide is a poisonous compound used as a

fumigant. This is one reason why the body jettisons the " Vitamin

B12 " (i.e., cyanocobalamin) injections so rapidly. Within 24 hours

most (about 90%) of the cyanocobalamin in supplements has been

eliminated.

The names of cobalamins formed by the body or in a laboratory are:

l. hydroxocobalamin if it combines with a hydroxyl ion (OH), and 2.

aquocobalamin, when it combines with water. Cobalamin also combines

with anions such as nitrite a form of nitrogen, chloride, and

sulfur. These are not usable by the body. The two active coenzymes

that can be formed in the body after stripping off the cyanide are

5'deoxyadenosylcobalamin, or adenosylcobalamin for short, and

methylcobalamin. The problem is that the cyanide is toxic and makes

many people sicker than they were before taking the supplement.

Cyanocobalamin is in every vitamin B12 supplement known because it

is stable and less costly to manufacture. But it is not usable in

the body. If the body has sufficient energy it may be able to

offload the cyanide and benefit from the useful component. Mainly,

what people experience after taking cyanocobalamin supplements is

stimulation. The toxic effect of the cyanide triggers a rush of

energy as the body works hard to excrete the poison, and this fools

people into believing that the supplement has " worked " to heal them.

Meanwhile, if their blood tests show an increase in B12, it mainly

reflects the amount of the cyanocobalamin in the blood stream. The

usable forms are carried into the cells and can't be discovered by

testing the blood as is the current practice. Blood tests are often

inaccurate and, as previously stated, in the case of cyanocobalamin

supplementation and B12 injections, about 90 % of it has been

eliminated from the body in 24 hours.

Looking at it Hygienically, no Vitamin B12 therapy can cause a

recovery from any so-called deficiency disease. It may only hide the

symptoms and cannot promote health. When people report that their

apparent B12 deficiency symptoms have been relieved by

cyanocobalamin supplementation, they are mistaken. They are not

getting usable Vitamin B12 coenzymes, and their bodies are forced to

convert the cyanide form into the active forms, methylcobalamin, and

adenosylcobalamin. This extra function stimulates but wastes nerve

energy, and they are are actually getting worse, not better. They

have not addressed the cause of their troubles.

In summary, vegans and raw fooders all have sufficient amounts of

coenzyme B12 in their diets, and from that produced in their bodies.

The most common basic cause of a natural cobalamin deficiency is a

failure to digest, absorb and utilize the various cobalamins from

food and from the intestinal tract as in the case of gastritis or

gastroenteritis. The cause of malabsorption is commonly a

gastrointestinal disorder and this was known by pathologists way

back in the l800s. In this case, one's lifestyle must be assessed

and brought into unison with the needs of the living organism.

Furthermore, absorption of the natural B12 coenzymes can take place

in the mouth, throat, esophagus, bronchial tubes and even in the

upper small intestines, as well as all along the intestinal tract.

This does not involve the complex enzyme mechanism for absorption

(intrinsic factor) in the small intestine as required by

cyanocobalamin. The coenzymes are absorbed by diffusion through

mucous membranes.

---------------------------------

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October 11, 2006

From http://www.strokedoctor.com/vitamin_b12.htm

" Vitamin B12: All Cobalamins are not Equal

Look at your multiple vitamin or B complex bottle. You're probably

taking cyanocobalamin, the stable and less expensive form of vitamin

B12. Because it is stable, it has a longer shelf life. However, the

active form of B12 is methylcobalamin and the two are NOT equal in

effectiveness. If you have symptoms of GI disorders, lethargy,

confusion, slow thought processes, heart rate variability,

atherosclerosis, sleep disorders, or immune dysfunction, you may

need the methyl as well as the cobalamin component.

The two vitamin B12 coenzymes known to be metabolically active in

humans are methylcobalamin and adenosylcobalamin. Vitamin B12 is

usually absorbed from the gut from the fermentation of intrinsic

factor by intestinal flora. However, production can be disturbed by

nutritional deficiencies, intrinsic factor deficiency, bacterial

overgrowth, malabsorption, alcohol, and antibiotics. Nitrous oxide

anesthesia in surgery and nitric acid from normal metabolism and

inflammation also reduce our vitamin B12 levels.

Cobalamins are destroyed by heavy metals and strong oxidizing or

reducing agents. (take at different times than vit c). Vitamin B12

deficiency generally increases with age and is common in the elderly.

(2)

Both vitamin B12 and folic acid are required for the synthesis of

thymidylate, a component of DNA. Lack of adequate DNA synthesis

causes many red blood cell precursors (hematopoietic cells) to die

in the bone marrow. The development of epithelial cells is also

disturbed by thymidylate deficiency. Gut changes due to vitamin B12

deficiency are often related to constipation whereas a folic acid

deficiency is generally related to diarrhea. In the brain, the

arrest of cell replication due to vitamin B12 deficiency disrupts

myelin synthesis, resulting in neural damage in the brain, spinal

cord and/or peripheral nerves. Vitamin B12 deficiency can include

the following neurological symptoms: numbness and tingling in the

hands and feet, unsteadiness, poor muscular coordination, moodiness,

mental slowness, poor memory, confusion, agitation, and/or

depression.

Vitamin B12 is involved in fat and carbohydrate metabolism. It is

required in the synthesis of the amino acid methionine, which is

involved in choline and betaine utilization. B12 assists in

maintaining sulfhydryl (SH) groups in their reduced form for enzyme

activity. Vitamin B12 deficiency is associated with a decrease of

reduced glutathione, needed for cell defense against pathogens

(viruses, bacteria, fungi) and toxins.

Methylcobalamin is a co-factor of methionine synthase, an enzyme

that transfers methyl groups to homocysteine to regenerate

methionine. Elevated homocysteine levels are a risk factor for

coronary artery disease. (11) Methionine can be transformed to S-

adenoxylmethionine (SAM) that is involved in a variety of

methylation reactions in the body, one of which is alleviating

depression.(13)

Methylcobalamin also plays a role in cell-mediated and humoral

immune function in rats. In vitamin B12 deficient rats, serum C3,

IgM and Ig G factors were found to be lower. There was also an

elevation of the ratio of CD4+ CD8- to DC4- CD8+, which reduces the

ability to fight off pathogens.(12)

Cyanocobalamin is not biologically active until converted to

methylcobalamin, which also means releasing its cyanide. Cyanide can

be toxic because it binds the iron (F3+) portion of cytochrome

oxidases, preventing its reduction. This binding blocks electron

transport and interrupts cellular respiration. Symptoms of sublethal

cyanide toxicity include hypotension, tachypnea, and tachycardia.(4)

Cobalamin can bind with cyanide and is therefore effective in

reducing cyanide toxicity. However cyanocobalamin is not effective

in removing cyanide because the cobalamin is already bound. (3)

Since nitroprusside can induce cyanide toxicity, other cobalamins

such as hydroxocobalamin should be used to bind with cyanide.

Nitroprusside therapies should be minimized in critically ill

patients and those with liver or kidney dysfunction.

Large amounts of cyanocobalamin can exacerbate preexisting cyanide

toxicity that can result from smoking tobacco, sodium nitroprusside

therapy, and phagocytosis. Steve Roach, M.D. writes that " it seems

wise to avoid a potentially harmful form of a drug when the more

physiologic variety is available and is excreted at a more desirable

rate.(7)

Foods fortified with vitamin B12 (as cyanocobalamin) may be a

potential problem if cooked. The highest mutation activity in cooked

(pyrolysate) vitamins was found in cyanocobalamin (3220 revertants

at .025 mumole of cyanocobalamin).(5)

In a comparison of cobalamins against cancer, adenoxylcobalamin was

effective against fast-growing malignant cells. Methylcobalamin was

effective at elevated concentrations and cyanocobalamin had no

effect in slowing the growth of any of the tumor cell lines studied.

(6) In studies that show that vitamin B12 has no effect on cancer

growth, we need to look closer at whether cyanocobalamin was used

instead of the natural coenzyme forms (adenoxylcobalamin and

methylcobalamin).

Methylcobalamin enhances synaptic transmission in learning and

memory. Ikeuchi and associates studied the effects of methyl-B12 on

the electrical activity in hippocampal neurons and found that methyl-

B12 increased post-synaptic field potential which lasted more than

an hour and increased the electrical currents elicited by N-methyl-D-

aspartate (NMDA). Cyanocobalamin had no effect.(13)

Methylcobalamin plays a role in modulating human circadian rhythms.

It accelerates re-entrainment of the activity rhythm to the

environmental light-dark cycle. The suprachiasmatic nucleus (SCN) is

involved in relaying photic information to the pineal gland.

Methylcobalamin enhanced the field potential in the SCN that lasted

an hour. In contrast, cyanocobalamin showed no effect.(16)

Methylcobalamin is also required in donating a methyl group for the

synthesis of melatonin. Methylcobalamin supplementation can assist

in modulating melatonin secretion, enhancing light-sensitivity,

normalizing circadian rhythms and improving sleep-wake cycles. (17)

Methylcobalamin also helps improve heart rate variability,

suggesting that it is involved in balancing sympathetic and

parasympathetic nervous system function,(18) perhaps through its

involvement with light entrainment and melatonin synthesis. Since

circadian rhythm and melatonin synthesis are key factors in health

maintenance, the use of cyanocobalamin rather than methylcobalamin

is undermining our health as individuals as well as a nation.

Another study found a correlation between serum vitamin B12 in women

and their breast milk. When a group of lactating women were injected

with cyanocobalamin, there was also an increase of cyanocobalamin in

their breast milk.

As early as 1970, Dr. A.G. Freeman protested against the use of

cyanocobalamin in The Lancet. He again wrote a letter in 1978,

entitled " Why Has Cyanocobalamin Not Been Withdrawn? " to The Lancet

and to the British Committee on Safety of Drugs. Dr. Freeman voiced

the concern that even if hydroxocobalamin is prescribed,

cyanocobalamin is administered in its place. They wrote

that " because doctors are still confused about the differences

between various forms of vitamin B12 commercially available and

about their possible adverse effects, manufacturers should withdraw

cyanocobalamin in favor of hydroxocobalamin for therapeutic use. " (8)

A letter from Dr. Terry was published in the October, 1978 issue of

The Lancet. He wrote that " the lead for improved prescribing must

come form compilers of formularies that are highly regarded. In this

respect it is disappointing to find that the W.H.O. expert committee

on the selection of essentiald rugs lists only cyanocobalamin,

placing an incalculable number of patients with optic neuropathy in

pernicious anemia or tobacco and tropical amblyopia at risk. " (9)

In the November 1978 issue, the Lancet published a letter by

J.C.Linnell and associates entitled " Therapeutic Misuse of

Cyanocobalamin. " The authors state that cyanocobalamin itself has no

known biochemical function. Only trace amounts of cyanocobalmin are

normally detectable in the human body, while significant amounts

occur in patients with optic neuropathies, inborn errors of

cobalamin metabolism and pernicious anemia. Cyanocobalamin must

first undergo conversion to the physiological forms of cobalamin

before being effective against pernicious anemia. However

hydroxocobalamin (a precursor to methyl and andenoxylcobalamin) " has

the additional advantage of therapeutic efficacy in certain

neuropathies and some cases of inborn errors of cobalamin

metabolism. " The authors further write that " it is lamentable that

an extensive demand for cyanocobalamin as a therapeutic agent should

persist. There seems to be no place for the continued therapeutic

use of cyanocobalamin. " (10)

Vitamin B12 is found in algae, peas, clover, alfalfa, mustard, egg

yolk, chedder cheese, sardines, herring, anchovies, calve's liver,

haddock, salmon, and cow's milk. Plants containing S-

methylmethionine include cabbage, kohlrabi, turnip, tomatoes,

celery, leeks, garlic, beets, raspberries and strawberries (14).

Cyanocobalamin is in haddock and cassava root. Elevated amounts of

cyanocobalamin have been found in smokers and cases of amyotrophic

lateral sclerosis and optic atrophy.

Clinical doses of methylcobalamin are 1500-6000 mcg per day and can

be administered orally, intramuscularly or intravenously with

positive clinical results. Methylcobalamin is well tolerated and has

no known toxicity. B complex (riboflavin, folic acid, pyridoxine,

and choline), and zinc assist methylcobalamin effectiveness. It is

important that physicians giving injections check the source of

their vitamin B12. Not only can it be cyano rather than

methylcobalamin, but the shot gun approach of giving liver extract

can include allergenics. One report states that 10-30% of

pharmaceutical preparations may be noncobalamin analogues, that are

either inactive or cause allergic reactions. (1)

In conclusion, methylcobalamin can be effective in cases of

neuropathy, depression, cancer, optic atrophy, heart rate

variability, homocysteinemia, and sleep disturbances. However, all

cobalamin analogues are not equal and taking cyanocobalamin with

already elevated levels of cyanide can actually be harmful. It has

been thirty years since Dr. Freeman first published a letter in The

Lancet about the risks of using cyanocobalamin. How much longer can

we afford to allow ignorance and profit motives to undermine our

nation's health?

REFERENCES:

(1) Herbert, Victor and Neville Colman. " Folic Acid and Vitamin B12 "

in Shils, Maurice and Vernon R. Young, " Modern Nutrition in Health

and Disease. " Lea & Febinger, Philadelphia, PA, 1988, pg. 388-416.

(2) Watt, D.T. " Vitamin B12 replacement therapy: how much is

enough? " Wisconsin Medical Journal, 1994, 93(5): 203- 5.

(3) Zerbe, N.F. et al. " Use of vitamin B12 in the treatment and

prevention of nitroprusside-induced cyanide toxicity. " Critical Care

Medicine, 1993, 21(3): 465-7.

(4) , H.L. et al. " Studies of cobalamin vehicle for the

renal excretion of cyanide anion. " Journal of Laboratoyr and

Clinical Medicine, 1990, 116(1): 37-44.

(5) Demura, R. et al. " Mutagenic activity of pyrolysate of

cyanocobalamin and some other soluble vitamins in the model system

with the Salmonella/mammalian microsomes. " Mutation Research, 1990,

244(1): 37-42.

(6) Tsao, C.S. et al. " Cytotoxic activity of cobalamin in cultured

malignant and nonmalignant cells. " Pathobiology, 1990, 58(5): 292-6.

(7) Sawyer, D.R. " Cyanocobalmin and cyanide toxicity (letter). "

American Family Physician, 1982, 26(1): 48.50,55.

(8) Freeman, A.G. et al. " Why has cyanocobalamin not been

withdrawn? " The Lancet, April 8, 1978; pg. 777-778.

(9) Terry, S.I. et al. " Survival of Cyanocobalmin. " The Lancet,

October 14, 1978, pg. 848.

(10) Linnell, J.C. et al. " Therapeutic Misuse of Cyanocobalamin " .

Lancet, November 11, 1978; pg 1053-1054.

(11) Brown, C.A. et al. " A Common Polymorphism in Methionine

Synthase Reductase Increases Risk of Premature Coronary Artery

Disease. " J Cardiovasc Risk 2000, 7(3): 197-200.

(12) Funada, U. et al. " Changes in CD4+ CD8-/CD4- CD8+ ratio and

humoral immune functions in vitamin B12-deficient rats. " Int J Vitam

Nutr Res, 2000, 70(4): 167-71.

(13) Ikeuchi, Youji et al. " Methylcobalamin induces a long-lasting

enhancement of the postsynaptic field potential in hippocampal

slices of the guinea pig. " Neuroscience Leters, 1995, 192: 113-116.

(14) Kovatscheva, E.G. et al. " S-methylmethionine content in plant

and animal tissues and stability during storage. " Nahrung, 1977, 21

(6): 465-72.

(15) Schneider, Z. " Comprehensive B12. " Walter de Gruyter, New York,

New York, 1987.

(16) Nishikawa, Yukiko et al. " Methylcobalamin induces a long-

lasting enhancement of the field potential in rat suprachiasmatic

nucleus slices. " Neuroscience Letters, 1996: 220: 199-202.

(17) Mayer, G. et al. " Effects of vitamin B12 on performance and

circadian rhythm in normal subjects. " Neuropsychopharmacology, 1996;

15: 456-464.

(18) Yoshioka, K. et al. " Effect of methylcobalamin on diabetic

autonomic neuropathy as assessed by power spectral analysis of heart

rate variations. " Horm Metab Res, 1995, 27: 43-44 "

October 11, 2006

The first three patch sites talk about needing methylcobalamin but

list cyanocobalamin as the primary ingredient! Do you know of a better

brand?

>

> YOU CAN PULL B12 PATCHES UP ON THE WEB.

>

October 11, 2006

,

I would check to see if they give a money back guarantee, most

companies do, VivaTRU does. It certainly wouldn't hurt to ask, so

fish that bottle out of the garbage, and see if you can get your

money back before you toss it.

Cara

> Hi ,

> When I first got MS back in the 70', Gp's could prescribe vitamins

and the

> B12 was issued under the phama name Cytagon or Cemac. Shortly

after, my then

> Gp went to Sweden on a seminar for MS, he came back and

immediately put me

> on a twice a month 1000mg injection. Which in his words was worth

more than

> a bucket full of tablets. This continued till I went to see a

Naturopath and

> he checked not only my health also my ancestors health history. He

decided

> that B12 should be increased even more and that is the quantity

that I'm

> still taking 13 years later. I've told you that so you can see

both a medic

> and a Naturopath have both great believe in Vitamin B12. I can say

with

> great certainty because of Vit. B12, I do not suffer from the

dreaded MS

> fatigue. No injection sight problems, with the quantity that I

have now if

> there was any side effects my body would surely had suffered at

least one of

> them. As such I doubt the authenticity of the article.

> I don't take drugs only alternatives. Only one blip, IV steroids

which

> caused septicaemia, took my legs and bladder. To this I know I'm

not unique,

> I know others that have also lost the use of their legs. All books

I've read

> on MS alternative treatments, all state that Vitamin B12 is an

essential

> This is my believe.

> Re: Re: B-12

>

> ---------------------------------

> All-new Yahoo! Mail - Fire up a more powerful email and get

things done faster.

>

October 13, 2006

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The Science of the Vitamin B-12 Patch

Here is why you might not be getting your B12 with those other vitamins! When

the B-12 vitamin enters your body in the stomach (through food or oral pills),

acids in the stomach separate the B-12 from its protein source. It then must

combine with intrinsic factor cells in the stomach. This B12/intrinsic factor

complex travels to your intestine, where it is absorbed in the terminal ileum.

The absorbed complex is then transported via blood plasma and stored in the

liver. The interruption of any of these steps affects your body’s ability to

absorb B12.

Common B12 absorption problems

As you age (over 45) or become overly reliant on acid suppressing agents like

antacids, your ability to produce gastric acids in the stomach decreases,

meaning that the B12 is less likely to be released from its food source. An

autoimmune or other disease reduces the production or blocks the action of

intrinsic factor, resulting in intestinal malabsorption. People with pernicious

anemia have decreased production of intrinsic factor. Abdominal surgery reduces

B12 absorption. Gastrectomy eliminates the site of intrinsic factor production.

Blind loop syndrome results in competition for vitamin B12 by bacterial

overgrowth in the lumen of the small intestine. Surgical resection of the ileum

eliminates the site of vitamin B12 absorption. Pancreatic insufficiency such as

fish tapeworm infection and severe Crohn's disease affect absorption.

With the B12 Patch you can now have confidence knowing that

your body is getting the B12 it needs!

Not all substances are easily absorbed transdermally. A substance’s ability to

be absorbed is affected by its molecular stucture and molecular weight of the

substance. Our extensive background in biochemistry and nutrition, along with

years of study, make the Vitamin B-12 Patch second to none. Studies show that

blood levels of B-12 increase by only 1.2% when taken orally. While Vitamin B-12

Patch is readily absorbed into the bloodstream, raising blood levels up to 90%.

The Vitamin B-12 patch is completely safe and one of the most effective

patches available on the market today. Each Vitamin B-12 Patch is made under

the strictest quality controls in the industry. All manufacturing and laboratory

processes meet or exceed the most current Good Manufacturing Practices (GMP) as

published by the Food and Drug Administration.

The greatest thing about the Vitamin B-12 Patch is that it is so easy to take!

Place the patch (size of a dime) on your neck behind your earlobe for up to 24

hours. No more swallowing large, uncomfortable pills each day or cleaning up

messy powders. No more visits to the doctor for painful intramuscular B12 shots.

When you take the Vitamin B-12 Patch you can feel confident in knowing that your

body is getting the best source of vitamin B12 available.

tbayuk wrote: Would this be a good Vit. B-12 ??

Thank you.

What type of B-12 does your product contain?

The source for TriVita's patented Sublingual B-12 is cyanocobalamin, which is

derived through a fermentation process of cane molasses.

Regards,

Tom

October 13, 2006

The Vitamin B-12 Patch is a revolutionary product

developed to supply the body with vitamin B12 needed for: