Guest guest Posted March 24, 2004 Report Share Posted March 24, 2004 Namenda (brand name) (memantine is the generic name) (amantadine is a distant " cousin " ) is newly FDA approved and manufactured here in the US by Forest Labs. It is available in 5 mg and 10 mg tablets, so that indicates to me that your father received Namenda (amantadine comes in 100 mg strength). Excellent studies have been done with Namenda in combination with Aricept, so the Namenda is usually begun in addition to the usual dose of Aricept without alteration. (My mother takes both with good results.) They complement each other, but the addition of Namenda should be slowly titrated upward to a maximum dose of 10 mg morning and evening. I encourage you to look at the www.namenda.com webpage and www.memantine.com webpage to learn about it. It takes time to notice the possible effect - at least 3 weeks for my mother - and longer to notice the full effect. Her muscles became rigid as her dose increased so we lowered it back down to the initial dose and raised her by 2.5 mg (1/2 tablet) increments more slowly than the weekly dosage increase. I encourage p-a-t-i-e-n-c-e. One of the researchers, neurologist Dr. Farlowe at the Indiana University School of Medicine in Indianapolis, evaluated my mother last June and determined that she in fact suffers from LBD and that she was an appropriate patient to be given Namenda along with her Aricept. (She was not part of a study group.) She has been on it since July and maintains a good response to it. The only medication adjustment that Dr. Farlowe recommended was to decrease her Sinemet (carbidopa/levodopa combination) dosage and allowing her to stabilize at that level before adding the Namenda. I chose to jump the gun on US availability because my mother was readily declining in to late stage, so I arranged with her family physician to prescribe it so that I could procure it from the Netherlands until it was available here. A side note...this is a very expensive medication in both the 5 and 10 mg tablets. Because these patients can be so dosage sensitive I requested that my mother receive 5 mg tablets and take 1 tablet in the morning and two in the evening - as opposed to having the 10 mg tablet cut for her morning dose, in case the tablet isn't cut evenly (which is difficult to do with many tablets). My mother is covered by an excellent prescription benefit plan (much better than mine!)so she is very fortunate in that respect. Tablet splitting is a factor you may want to weigh carefully if you are faced with different morning and evening dosages. So many drug names are so similar and are easily confused in charting. Hospitals and nursing homes have pharmacists available to them (wherever the pharmacy source of their medications is)and you can certainly feel free call and discuss medications with those pharmacists. Given the HIPAA regulations in place, the pharmacist may be reluctant to discuss a particular patient's medication profile unless you are listed on a release of information form, but the pharmacist is free to discuss the medication in general and how it might interact with a list of medications your loved one is taking. You might consider offering a list and giving him or her time to do some research for you and calling you back at the pharmacist's convenience. If all of your loved one's medications are dispensed from the same pharmacy the pharmacist(s) are more likely to spot a possible drug interaction. Hoping this information helps- Deb > > > Well Dad has been out of it for the last few days at the rehab place - so I went to bug the nurses to see if they had given him any > sleep aid or something. > > In going through the chart I see he was on 5 mg of Namentadine ? What the heck is that ... no-one knew - couldn't find it in the PDR > etc ! But he's been getting it for 4 days so its pretty suspicious to me that he's been out of it for 3 ! > > SO I come home do an internet search and come up with this: > > Memantine - which is the new Alz drug - Nemanda - which I know some LBD folks try - so that might be OK - but if that's what it is - > its not helping dad thats for sure. > > OR > > Amantadine (no N and there is a second a) ... which is > For Parkinsonism, drug induced extrapyramidal reactions, prophylaxis of Influenza A and treatment of Influenza if > seen < than 20hrs after onset of illness; has ability to release dopamine; > > My theory is the doc called in Memantine and in the transciption it became Nemantadine and then Amantadine ant thats; what he is > getting ??? > > Let me know if you know anything about either of these two drugs > > thanks > > donna Quote Link to comment Share on other sites More sharing options...
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