Guest guest Posted September 10, 1999 Report Share Posted September 10, 1999 Jacquelyn, I know, it does seem a bit weird. But after a tx you have a healthy liver and it's able to handle the tylenol. Other otc pain meds may interfere with the other drugs we take post tx. Tim --- JQS2@... wrote: > Dear Biddy, > Just thought y'all would get a kick out of this > one....upon discharge > from the hospital following the tx...my docs only advice for > pain relief WAS > TYLENOL!!! How crazy is that??!! Or maybe I should say...how > crazy are > they??!! > Take care, > Jacquelyn __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 1999 Report Share Posted September 12, 1999 I've seen Biddy's post about no Tylenol. It's strange - - 10 different doctors, 10 different opinions. My Mayo dr. had no problem with my taking it occasionally and my GI dr in the tx clinic in Omaha didn't either. In fact, I told him I took Tylenol PM when needed for sleep and he said it was ok as long as it wasn't every night or excessive. I'm also now taking it for shoulder pain - I'll take that until the shoulder pain lets up. Don't know what's causing that--it's actually just under the shoulder blade - maybe too much time at computer at work? Everyone take care & hang in there. laurie, PSC, dx 3/87 (liver problems back to 1980) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 1999 Report Share Posted September 12, 1999 Dear Tim, Yes! You are absolutely right. They told me that if I take Advil or Aspirin that I would " immediately require a kidney tx " . I don't know how much faith I put into that one sentence, but trust me, I won't be taking any Advil or Aspirin.....since I'm no doctor. After your tx did you have problems with your other organs? My liver enzymes are perfectly normal (Praise the Lord), but I am having problems such as a collapsed inferior vena cava that causes tremendous pain, swelling and discoloration in the legs upon standing....And the doctors say that it is way too risky of a surgery to do so they say I'll just have to live with it. Also, I have been having recurrent kidney infections...I am now on Levaquin (the 4th antibiotic for this one infection) and I'm on Day 4 and am still in so much pain. Also, ever since about a month before tx I've been having severe GI problems (at the time we just thought it was the PSC), anyway, I won't go into much detail except to say that I'm getting so dehydrated at times that my Prograf levels are through the roof sometimes and other times hit the floor. My blood pressure is doing the same. Also I've been running a fever b/t 99-100 for over a month now. (Normal for me is 96-97) I'm so sorry to have complained so much, but I'm just curious if this is normal post tx and it just takes the body a while to recuperate...or if I need to keep prodding the doctors to get me an answer for all of this. I was admitted just recently for 10 days and they couldn't give us one good reason for the symptoms. My husband and I feel like a lot of it is due to the vena cava, but that the docs don't want to admit that b/c that was an error on their part. And we don't care about that....we just want everything fixed. Anyway, I have been so very blessed with a precious wonderful husband and two miracle babies ( 4 and Calvin 2)...both of which are sick today...so Mommy is a little stressed to say the least. Daddy's (Luke) out fishing a tournament today so I'm praying he brings home the big bucks!!!ha!! Again, I didn't mean for this letter to sound like I'm throwing myself a pity party...because I'm not...I am so very thankful for the blessings I've been given. And most of all the blessing of the Gift of Life....here on earth and eternally with Christ!!!! I guess I will close for now, but if you have time to just let me know if you've dealt with some of the same scenerios, please let me know. I'm just playing a guessing game every day it seems like!! Take care and thank you for your time. God Bless! Jacquelyn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 1999 Report Share Posted September 12, 1999 Jacquelyn, Do you think it is possible that your normal temperature should be higher (like normal people) post transplant whereas most PSCer's temps are usually below other peoples? I'm not saying that you aren't sick but I wonder if you normal temp might be higher post tx? That would be a good question for Tim or Dave. Just curious. We prayed for you in Sunday school class again today. Hope it helps. I know the prayers help us and I always appreciate how hard you pray for all of us. Love, Peg JQS2@... wrote: > Dear Tim, > Yes! You are absolutely right. They told me that if I take Advil or > Aspirin that I would " immediately require a kidney tx " . I don't know how > much faith I put into that one sentence, but trust me, I won't be taking any > Advil or Aspirin.....since I'm no doctor. > After your tx did you have problems with your other organs? My liver > enzymes are perfectly normal (Praise the Lord), but I am having problems such > as a collapsed inferior vena cava that causes tremendous pain, swelling and > discoloration in the legs upon standing....And the doctors say that it is way > too risky of a surgery to do so they say I'll just have to live with it. > Also, I have been having recurrent kidney infections...I am now on Levaquin > (the 4th antibiotic for this one infection) and I'm on Day 4 and am still in > so much pain. Also, ever since about a month before tx I've been having > severe GI problems (at the time we just thought it was the PSC), anyway, I > won't go into much detail except to say that I'm getting so dehydrated at > times that my Prograf levels are through the roof sometimes and other times > hit the floor. My blood pressure is doing the same. Also I've been running > a fever b/t 99-100 for over a month now. (Normal for me is 96-97) > I'm so sorry to have complained so much, but I'm just curious if this is > normal post tx and it just takes the body a while to recuperate...or if I > need to keep prodding the doctors to get me an answer for all of this. I was > admitted just recently for 10 days and they couldn't give us one good reason > for the symptoms. My husband and I feel like a lot of it is due to the vena > cava, but that the docs don't want to admit that b/c that was an error on > their part. And we don't care about that....we just want everything fixed. > Anyway, I have been so very blessed with a precious wonderful husband and > two miracle babies ( 4 and Calvin 2)...both of which are sick > today...so Mommy is a little stressed to say the least. Daddy's (Luke) out > fishing a tournament today so I'm praying he brings home the big bucks!!!ha!! > Again, I didn't mean for this letter to sound like I'm throwing myself a > pity party...because I'm not...I am so very thankful for the blessings I've > been given. And most of all the blessing of the Gift of Life....here on > earth and eternally with Christ!!!! > I guess I will close for now, but if you have time to just let me know if > you've dealt with some of the same scenerios, please let me know. I'm just > playing a guessing game every day it seems like!! > Take care and thank you for your time. > God Bless! > Jacquelyn > > ------------------------------------------------------------------------ > MyPoints-Free Rewards When You're Online. > Start with up to 150 Points for joining! > http://clickhere./click/805 > > eGroups.com home: /group/ > - Simplifying group communications Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 1999 Report Share Posted September 12, 1999 Hi Laurie! I think this Tylenol thing is just one of the things about this " devil " disease that is so confusing to the sufferers! Mayo says OK, another doc says OK, another says what is the problem with Tylenol, etc., etc., etc. Since your post I know that Tylenol is the only thing that will touch a headache for me and it helps with the arthritis. I take Percoset and I know it has Tylenol in it, but the doctors don't seem to worry that much about this -- go figure!! I have so many ulcers now and I know I can never take aspirin (I haven't taken this for years because I have had an ulcer (one) before). I am so totally confused about this horrible disease it is so very frustrating. Hugs, Biddy Re: Tylenol >I've seen Biddy's post about no Tylenol. It's strange - - 10 different >doctors, 10 different opinions. My Mayo dr. had no problem with my taking it >occasionally and my GI dr in the tx clinic in Omaha didn't either. In fact, >I told him I took Tylenol PM when needed for sleep and he said it was ok as >long as it wasn't every night or excessive. I'm also now taking it for >shoulder pain - I'll take that until the shoulder pain lets up. Don't know >what's causing that--it's actually just under the shoulder blade - maybe too >much time at computer at work? > >Everyone take care & hang in there. > >laurie, PSC, dx 3/87 (liver problems back to 1980) > >------------------------------------------------------------------------ >MyPoints-Free Rewards When You're Online. >Start with up to 150 Points for joining! >http://clickhere./click/805 > > >eGroups.com home: /group/ > - Simplifying group communications > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 1999 Report Share Posted September 12, 1999 Jacquelyn, Because cyclosporin and tacrolimus (Neoral and Prograf) are toxic to kidneys, one post tx concern is to limit kidney damage. Tylenol is easy on kidneys the others stress the kidneys. The statement you report sounds like a scare tactic to me, but it does happen that years after a liver tx a kidney tx is needed. Tim ltx 4/4/98 --- JQS2@... wrote: > Dear Tim, > Yes! You are absolutely right. They told me that if I > take Advil or > Aspirin that I would " immediately require a kidney tx " . I > don't know how > much faith I put into that one sentence, but trust me, I won't > be taking any > Advil or Aspirin.....since I'm no doctor. __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 Peg, Even as a child my temp was always much lower than normal. When I was about 7, my temp got up to 100. ? and I started to have hallucinations. But, I suppose I did have health problems at that time also. My " soft spot " wasn't completely healed up, my lungs weren't fully developed, and my bones were 3-4 years behind in growth. Strange considering my mother carried me to full term. I don't think they ever checked my liver at that time, so I wouldn't know if my liver enzymes were elevated or not. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 So your saying that some of us that have a liver tx will alsohave to have a kidney tx someday? What is the reason for that? Thanks Vicki 38 dx PSC 6/99 Ohio Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 Laurie, I've had chronic right shoulder pain for over 10 years. I initially associated it with bicycle riding (preparing for a 100 mile ride), but now wondering if it has anything to do with PSC based on an article on pain mentioned previously in the group. Dan > Re: Tylenol > > I've seen Biddy's post about no Tylenol. It's strange - - 10 different > doctors, 10 different opinions. My Mayo dr. had no problem with my taking > it > occasionally and my GI dr in the tx clinic in Omaha didn't either. In > fact, > I told him I took Tylenol PM when needed for sleep and he said it was ok > as > long as it wasn't every night or excessive. I'm also now taking it for > shoulder pain - I'll take that until the shoulder pain lets up. Don't > know > what's causing that--it's actually just under the shoulder blade - maybe > too > much time at computer at work? > > Everyone take care & hang in there. > > laurie, PSC, dx 3/87 (liver problems back to 1980) > > ------------------------------------------------------------------------ > MyPoints-Free Rewards When You're Online. > Start with up to 150 Points for joining! > http://clickhere./click/805 > > > eGroups.com home: /group/ > - Simplifying group communications > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 I just reread my post because I post both from work and home and I noticed my first sentence. I didn't mean to infer that PSCer's were not normal people :-) Phil & Peggy Alfeld wrote: > Jacquelyn, > Do you think it is possible that your normal temperature should be higher (like > normal people) post transplant whereas most PSCer's temps are usually below other > peoples? I'm not saying that you aren't sick but I wonder if you normal temp > might be higher post tx? That would be a good question for Tim or Dave. Just > curious. > > We prayed for you in Sunday school class again today. Hope it helps. I know the > prayers help us and I always appreciate how hard you pray for all of us. > > Love, > Peg > > JQS2@... wrote: > > > Dear Tim, > > Yes! You are absolutely right. They told me that if I take Advil or > > Aspirin that I would " immediately require a kidney tx " . I don't know how > > much faith I put into that one sentence, but trust me, I won't be taking any > > Advil or Aspirin.....since I'm no doctor. > > After your tx did you have problems with your other organs? My liver > > enzymes are perfectly normal (Praise the Lord), but I am having problems such > > as a collapsed inferior vena cava that causes tremendous pain, swelling and > > discoloration in the legs upon standing....And the doctors say that it is way > > too risky of a surgery to do so they say I'll just have to live with it. > > Also, I have been having recurrent kidney infections...I am now on Levaquin > > (the 4th antibiotic for this one infection) and I'm on Day 4 and am still in > > so much pain. Also, ever since about a month before tx I've been having > > severe GI problems (at the time we just thought it was the PSC), anyway, I > > won't go into much detail except to say that I'm getting so dehydrated at > > times that my Prograf levels are through the roof sometimes and other times > > hit the floor. My blood pressure is doing the same. Also I've been running > > a fever b/t 99-100 for over a month now. (Normal for me is 96-97) > > I'm so sorry to have complained so much, but I'm just curious if this is > > normal post tx and it just takes the body a while to recuperate...or if I > > need to keep prodding the doctors to get me an answer for all of this. I was > > admitted just recently for 10 days and they couldn't give us one good reason > > for the symptoms. My husband and I feel like a lot of it is due to the vena > > cava, but that the docs don't want to admit that b/c that was an error on > > their part. And we don't care about that....we just want everything fixed. > > Anyway, I have been so very blessed with a precious wonderful husband and > > two miracle babies ( 4 and Calvin 2)...both of which are sick > > today...so Mommy is a little stressed to say the least. Daddy's (Luke) out > > fishing a tournament today so I'm praying he brings home the big bucks!!!ha!! > > Again, I didn't mean for this letter to sound like I'm throwing myself a > > pity party...because I'm not...I am so very thankful for the blessings I've > > been given. And most of all the blessing of the Gift of Life....here on > > earth and eternally with Christ!!!! > > I guess I will close for now, but if you have time to just let me know if > > you've dealt with some of the same scenerios, please let me know. I'm just > > playing a guessing game every day it seems like!! > > Take care and thank you for your time. > > God Bless! > > Jacquelyn > > > > ------------------------------------------------------------------------ > > MyPoints-Free Rewards When You're Online. > > Start with up to 150 Points for joining! > > http://clickhere./click/805 > > > > eGroups.com home: /group/ > > - Simplifying group communications > > ------------------------------------------------------------------------ > MyPoints-Free Rewards When You're Online. > Start with up to 150 Points for joining! > http://clickhere./click/805 > > eGroups.com home: /group/ > - Simplifying group communications Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 Peg, Who says we're normal? : ) Dan > Re: Tylenol > > I just reread my post because I post both from work and home and I noticed > my first > sentence. I didn't mean to infer that PSCer's were not normal people :-) > > Phil & Peggy Alfeld wrote: > > > Jacquelyn, > > Do you think it is possible that your normal temperature should be > higher (like > > normal people) post transplant whereas most PSCer's temps are usually > below other > > peoples? I'm not saying that you aren't sick but I wonder if you normal > temp > > might be higher post tx? That would be a good question for Tim or Dave. > Just > > curious. > > > > We prayed for you in Sunday school class again today. Hope it helps. I > know the > > prayers help us and I always appreciate how hard you pray for all of us. > > > > Love, > > Peg > > > > JQS2@... wrote: > > > > > Dear Tim, > > > Yes! You are absolutely right. They told me that if I take Advil > or > > > Aspirin that I would " immediately require a kidney tx " . I don't know > how > > > much faith I put into that one sentence, but trust me, I won't be > taking any > > > Advil or Aspirin.....since I'm no doctor. > > > After your tx did you have problems with your other organs? My > liver > > > enzymes are perfectly normal (Praise the Lord), but I am having > problems such > > > as a collapsed inferior vena cava that causes tremendous pain, > swelling and > > > discoloration in the legs upon standing....And the doctors say that it > is way > > > too risky of a surgery to do so they say I'll just have to live with > it. > > > Also, I have been having recurrent kidney infections...I am now on > Levaquin > > > (the 4th antibiotic for this one infection) and I'm on Day 4 and am > still in > > > so much pain. Also, ever since about a month before tx I've been > having > > > severe GI problems (at the time we just thought it was the PSC), > anyway, I > > > won't go into much detail except to say that I'm getting so dehydrated > at > > > times that my Prograf levels are through the roof sometimes and other > times > > > hit the floor. My blood pressure is doing the same. Also I've been > running > > > a fever b/t 99-100 for over a month now. (Normal for me is 96-97) > > > I'm so sorry to have complained so much, but I'm just curious if > this is > > > normal post tx and it just takes the body a while to recuperate...or > if I > > > need to keep prodding the doctors to get me an answer for all of this. > I was > > > admitted just recently for 10 days and they couldn't give us one good > reason > > > for the symptoms. My husband and I feel like a lot of it is due to > the vena > > > cava, but that the docs don't want to admit that b/c that was an error > on > > > their part. And we don't care about that....we just want everything > fixed. > > > Anyway, I have been so very blessed with a precious wonderful > husband and > > > two miracle babies ( 4 and Calvin 2)...both of which are sick > > > today...so Mommy is a little stressed to say the least. Daddy's > (Luke) out > > > fishing a tournament today so I'm praying he brings home the big > bucks!!!ha!! > > > Again, I didn't mean for this letter to sound like I'm throwing > myself a > > > pity party...because I'm not...I am so very thankful for the blessings > I've > > > been given. And most of all the blessing of the Gift of Life....here > on > > > earth and eternally with Christ!!!! > > > I guess I will close for now, but if you have time to just let me > know if > > > you've dealt with some of the same scenerios, please let me know. I'm > just > > > playing a guessing game every day it seems like!! > > > Take care and thank you for your time. > > > God Bless! > > > Jacquelyn > > > > > > > ------------------------------------------------------------------------ > > > MyPoints-Free Rewards When You're Online. > > > Start with up to 150 Points for joining! > > > http://clickhere./click/805 > > > > > > eGroups.com home: /group/ > > > - Simplifying group communications > > > > ------------------------------------------------------------------------ > > MyPoints-Free Rewards When You're Online. > > Start with up to 150 Points for joining! > > http://clickhere./click/805 > > > > eGroups.com home: /group/ > > - Simplifying group communications > > > > > ------------------------------------------------------------------------ > MyPoints-Free Rewards When You're Online. > Start with up to 150 Points for joining! > http://clickhere./click/805 > > > eGroups.com home: /group/ > - Simplifying group communications > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 1999 Report Share Posted September 13, 1999 --- Sleepy5916@... wrote: > So your saying that some of us that have a liver tx will > also have to have a kidney tx someday? That is probably true without any reasoning to back it up. > What is the reason for that? > Thanks Vicki 38 dx PSC 6/99 Ohio The reason for a lot of transplant related kidney failure is the toxicity to the kidneys of the drugs that are given to keep the transplant from being rejected. Of course the object is to keep the transplant without harming other organs, but sometimes a drug level which doen't harm the kidneys allows rejection, so a compromise dose is given in the hope that something better will come along and allow a better treatment. Drug companies are constantly running studies to try to find effective drugs that are not as toxic. The reason tylenol is allowed post transplant is that it is processed in the liver. Other pain meds are processed by the kidneys, putting more stress on the already stressed kidneys. Tim ltx 4/4/98 __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 So that would be all the better if a bone marrow transplant could be given with the liver to avoid the post transplant drugs. Peg Romlein wrote: > --- Sleepy5916@... wrote: > > So your saying that some of us that have a liver tx will > > also have to have a kidney tx someday? > > That is probably true without any reasoning to back it up. > > > What is the reason for that? > > Thanks Vicki 38 dx PSC 6/99 Ohio > > The reason for a lot of transplant related kidney failure is the > toxicity to the kidneys of the drugs that are given to keep the > transplant from being rejected. Of course the object is to keep > the transplant without harming other organs, but sometimes a > drug level which doen't harm the kidneys allows rejection, so a > compromise dose is given in the hope that something better will > come along and allow a better treatment. Drug companies are > constantly running studies to try to find effective drugs that > are not as toxic. > > The reason tylenol is allowed post transplant is that it is > processed in the liver. Other pain meds are processed by the > kidneys, putting more stress on the already stressed kidneys. > > Tim ltx 4/4/98 > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 After my last liver biopsy, they told me I'd probably have pain in my right shoulder, and sure enough I did! They said that it was pretty common for pain in that area to cause shoulder pain, so it's at least possible that the chronic shoulder pain could be caused by the PSC. athan Dan Bertles wrote: > > Laurie, > > I've had chronic right shoulder pain for over 10 years. I initially > associated it with bicycle riding (preparing for a 100 mile ride), but now > wondering if it has anything to do with PSC based on an article on pain > mentioned previously in the group. > > Dan > > > Re: Tylenol > > > > I've seen Biddy's post about no Tylenol. It's strange - - 10 different > > doctors, 10 different opinions. My Mayo dr. had no problem with my taking > > it > > occasionally and my GI dr in the tx clinic in Omaha didn't either. In > > fact, > > I told him I took Tylenol PM when needed for sleep and he said it was ok > > as > > long as it wasn't every night or excessive. I'm also now taking it for > > shoulder pain - I'll take that until the shoulder pain lets up. Don't > > know > > what's causing that--it's actually just under the shoulder blade - maybe > > too > > much time at computer at work? > > > > Everyone take care & hang in there. > > > > laurie, PSC, dx 3/87 (liver problems back to 1980) > > > > ------------------------------------------------------------------------ > > MyPoints-Free Rewards When You're Online. > > Start with up to 150 Points for joining! > > http://clickhere./click/805 > > > > > > eGroups.com home: /group/ > > - Simplifying group communications > > > > > > > > ---------------------------------------------------------------------- > [click here] > Click Here! > eGroups.com home: /group/ > www. - Simplifying group communications Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 Maybe. There have been trials of taking transplant patients off of immune suppressant drugs where their original autoimmune disease (PBC) returned and caused failure in the transplant. So it might depend on the original cause of liver failure. In general it's better to wait and get your transplant far in the future when more is known. Tim --- Peggy Alfeld wrote: > So that would be all the better if a bone marrow transplant > could be given > with the liver to avoid the post transplant drugs. > Peg > __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 Tim, thank you for the explanation. I was told by my transplant surgeon that drinking at least one gallon of water each day post-transplant would keep my system flushed to protect the kidneys from the transplant drugs. I have enjoyed all your very informed info related to our conditions. Thanks Tom PSC 1987 Ltx 1995 Re: Tylenol >--- Sleepy5916@... wrote: >> So your saying that some of us that have a liver tx will >> also have to have a kidney tx someday? > >That is probably true without any reasoning to back it up. > >> What is the reason for that? >> Thanks Vicki 38 dx PSC 6/99 Ohio > >The reason for a lot of transplant related kidney failure is the >toxicity to the kidneys of the drugs that are given to keep the >transplant from being rejected. Of course the object is to keep >the transplant without harming other organs, but sometimes a >drug level which doen't harm the kidneys allows rejection, so a >compromise dose is given in the hope that something better will >come along and allow a better treatment. Drug companies are >constantly running studies to try to find effective drugs that >are not as toxic. > >The reason tylenol is allowed post transplant is that it is >processed in the liver. Other pain meds are processed by the >kidneys, putting more stress on the already stressed kidneys. > >Tim ltx 4/4/98 >__________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 Tom, You're right - by drinking and making plenty of water available, the kidneys are not " asked " to reduce water loss by concentrating the urine. Thus they have less work to do, and lower concentrations of drugs to deal with (because the urine stays dilute) thus less toxicity. A gallon is a lot though - I'm sure I rarely drink that much! Tim ltx 4/4/98 --- " G. Black " wrote: > Tim, thank you for the explanation. I was told by my > transplant surgeon > that drinking at least one gallon of water each day > post-transplant would > keep my system flushed to protect the kidneys from the > transplant drugs. I > have enjoyed all your very informed info related to our > conditions. Thanks > > Tom PSC 1987 Ltx 1995 __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 1999 Report Share Posted September 14, 1999 Tom, I've been polling some info and I see you have been transplanted, would you please tell me your age and city and state where you live. Thanks Peg " G. Black " wrote: > Tim, thank you for the explanation. I was told by my transplant surgeon > that drinking at least one gallon of water each day post-transplant would > keep my system flushed to protect the kidneys from the transplant drugs. I > have enjoyed all your very informed info related to our conditions. Thanks > > Tom PSC 1987 Ltx 1995 > Re: Tylenol > > >--- Sleepy5916@... wrote: > >> So your saying that some of us that have a liver tx will > >> also have to have a kidney tx someday? > > > >That is probably true without any reasoning to back it up. > > > >> What is the reason for that? > >> Thanks Vicki 38 dx PSC 6/99 Ohio > > > >The reason for a lot of transplant related kidney failure is the > >toxicity to the kidneys of the drugs that are given to keep the > >transplant from being rejected. Of course the object is to keep > >the transplant without harming other organs, but sometimes a > >drug level which doen't harm the kidneys allows rejection, so a > >compromise dose is given in the hope that something better will > >come along and allow a better treatment. Drug companies are > >constantly running studies to try to find effective drugs that > >are not as toxic. > > > >The reason tylenol is allowed post transplant is that it is > >processed in the liver. Other pain meds are processed by the > >kidneys, putting more stress on the already stressed kidneys. > > > >Tim ltx 4/4/98 > >__________________________________________________ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 16, 1999 Report Share Posted September 16, 1999 Some additional comment on cyclosporine (Neoral) from Dr. Punch: >>[Doctors] say that cyclosporine has a narrow therapeutic window, meaning that the difference between a dose that causes side effects, and the dose that is necessary for an immuno- suppressive effect is small. Yes, cyclosporines can cause problems with kidney functions, particularly when the blood level is too high. Transplanters are interested in combinations of drugs that do not cause kidney function problems, and research into which combinations are optimal is occurring continually. Jeff Punch jpunch@... << original article:/group//?start=4337 > --- Sleepy5916@... wrote: > > So your saying that some of us that have a liver tx will need > > a kidney tx? > > Thanks Vicki 38 dx PSC 6/99 Ohio > > The reason for a lot of transplant related kidney failure is the > toxicity to the kidneys of the drugs that are given to keep the > transplant from being rejected. Of course the object is to keep > the transplant without harming other organs, but sometimes a > drug level which doen't harm the kidneys allows rejection, so a > compromise dose is given in the hope that something better will > come along and allow a better treatment. Drug companies are > constantly running studies to try to find effective drugs that > are not as toxic. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 1999 Report Share Posted September 21, 1999 Dear , I do agree with you....they're really quick to hand out those scare tactics!!! Take care, Jacquelyn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 1999 Report Share Posted September 21, 1999 Dear Vicki, I am so sorry if I said anything about liver tx patients needing kidney txs later on down the line....That is not my place to say that. I am not a doctor and as I've said...God is in control. It's just that some of the antirejection drugs are toxic to the kidneys and have caused a little trouble with my kidneys, but certainly nothing life threatening. So please please forget that I ever mentioned kidney txs!!! I am soooo sorry to have alarmed anyone!!!! We will all be fine and none of us will need additional txs!!!!! Trusting in God!!! Love, Jacquelyn Quote Link to comment Share on other sites More sharing options...
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