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RE: Kidneys > WAS > Prostate Cancer Gene breakthrough

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Hi ,

Re. your kidney ultrasound. Was your creatinine (part of renal blood test) elevated, or has something else prompted the u/s?

I've just been that route, so if your creatinine is elevated, I have a little recently aquired knowledge that might be of help.

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Prostate Cancer Gene breakthroughHullo allJust looking at Breakfast news on BBC1 television and Professor Colin was on talking about the work he has done on identifying the tigersfrom the pussy cats.They are sufficiently pleased with progress to publicise their work at theInstitute of Cancer Research Everyman Centre.They point to the E2F3 gene as the culprit - there is none in the normalhealthy prostate but research points to the fact that the percentageincreases with agressiveness. This I hope is the beginning of a new choicetechnique for the newly diagnosed and a prelude to open house screening inthe UK!Best wishesPS I have to have ultrasound to check my kidneys following my blood testsyesterday, the good news is this can be done at York! I was also offered acopy of the letter from the hospital to my urologist and GP!

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Possibly it was from the blood test yesterday - I'm sorry I didn't go into detail but anything that you can tell me about your experience would be good. Evidently this could be scarring n the urtethra that could be holding urine back.

Prostate Cancer Gene breakthroughHullo allJust looking at Breakfast news on BBC1 television and Professor Colin was on talking about the work he has done on identifying the tigersfrom the pussy cats.They are sufficiently pleased with progress to publicise their work at theInstitute of Cancer Research Everyman Centre.They point to the E2F3 gene as the culprit - there is none in the normalhealthy prostate but research points to the fact that the percentageincreases with agressiveness. This I hope is the beginning of a new choicetechnique for the newly diagnosed and a prelude to open house screening inthe UK!Best wishesPS I have to have ultrasound to check my kidneys following my blood testsyesterday, the good news is this can be done at York! I was also offered acopy of the letter from the hospital to my urologist and GP!

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Hi ,

If urine is being held back in volume, or if the outlet tube (ureter) from a kidney is (partially) blocked, then kidney function may be impaired. This shows in renal function blood tests as an elevated (and rising) creatinine level. The normal creatinine range is up to approx 124 umol/L. Urea is usually elevated too, normal range approx 2.5 - 6.6 mmol/L.

Ultrasound is used to check for kidney dilation and ureter dilation. If dilation is present and creatinine is raised, these indicate that back pressure of urine in the ureter(s) is causing the kidney(s) function to deteriorate. The ultrasound will also show residual urine volume in the bladder after peeing.

It is perfectly possible that your checks have nothing to do with kidney performance, but until you know what's going on, there are three simple things you could be doing, just in case.

1. If you have any influence over bringing the ultrasound and its conclusions forward, use it. Kidney function lost over time due to back pressure will recover to a degree, but not fully.

2. Have your blood pressure checked. Anything in the 120s over 80s is OK, but higher levels are likely to exacerbate declining kidney function.

3. If you take NSAIDs, for example ibuprofen, STOP (after early discussion with your doc, if they are prescribed). Chronic NSAID use can lead to impaired kidney function, and although stopping their use is usually followed by function return, permanent damage can be done. The use of NSAIDs if function is already impaired, risks further impairment.

Although my ultrasound was performed quickly when it was thought I had a partially blocked ureter (which I had), I didn't learn of points 2 & 3 until some time later despite a raised BP and NSAID use! Another piece of advice I was given was to drink a lot of water. I don't know if that advice applies in your situation.

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Prostate Cancer Gene breakthroughHullo allJust looking at Breakfast news on BBC1 television and Professor Colin was on talking about the work he has done on identifying the tigersfrom the pussy cats.They are sufficiently pleased with progress to publicise their work at theInstitute of Cancer Research Everyman Centre.They point to the E2F3 gene as the culprit - there is none in the normalhealthy prostate but research points to the fact that the percentageincreases with agressiveness. This I hope is the beginning of a new choicetechnique for the newly diagnosed and a prelude to open house screening inthe UK!Best wishesPS I have to have ultrasound to check my kidneys following my blood testsyesterday, the good news is this can be done at York! I was also offered acopy of the letter from the hospital to my urologist and GP!

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gave me lots of data about kidney ultrasound, I am very grateful for this.

I have noted some posts that came from new members that I haven't had chance to reply.

This doesn't mean that we don't appreciate hearing from you!

Best wishes to you all

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